Datura Wrightii - Fluticasone Furoate, Umeclidinium, Vilanterol Interaction Details

Interaction Details

Fluticasone Furoate, Umeclidinium, Vilanterol is classified as belonging to the following category: Anticholinergic Drugs

Datura wrightii contains atropine and scopolamine, as well as other tropane alkaloids with anticholinergic activity. Concomitant use of Datura wrightii with anticholinergic drugs might increase anticholinergic effects and adverse effects. Some anticholinergic drugs include amantadine, atropine, belladonna alkaloids, phenothiazines, scopolamine, and tricyclic antidepressants.

Interaction Rating

Moderate

Likelihood of Occurrence

Probable

Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.

References

Adams, JD Jr, Garcia C. Spirit, Mind and Body in Chumash Healing. Evid Based Complement Alternat Med 2005;2(4):459-463.
Evans WC, Woolley JG. The alkaloids of Datura meteloides D.C. J Chem Soc Perkin 1. 1965;4936-4939.

Fluticasone Furoate, Umeclidinium, Vilanterol Overview

The combination of fluticasone, umeclidinium, and vilanterol is used to control wheezing, shortness of breath, coughing, and chest tightness caused by chronic obstructive pulmonary (COPD; a group of diseases that affect the lungs and airways, that includes chronic bronchitis and emphysema). It is also used in adults to control wheezing, shortness of breath, coughing, and chest tightness caused by asthma. Fluticasone is in a class of medications called steroids. Umeclidinium is in a class of medication called anticholinergics. Vilanterol is in a class of medications called long-acting beta-agonists (LABAs). The combination of fluticasone, umeclidinium, and vilanterol works by relaxing and opening air passages in the lungs, making it easier to breathe.

See More Information Regarding Fluticasone, Umeclidinium, and Vilanterol Oral Inhalation

Datura Wrightii - More Interactions

Datura Wrightii interacts with 224 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.

Major	The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur.
Moderate	Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur.
Minor	Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction.
Unknown	No interactions have been reported or no interaction data is currently available.