Dimethylsulfoxide (dmso) - Symdeko (Tezacaftor, Ivacaftor) Interaction
Herbal: Dimethylsulfoxide (dmso)
Also Known As: Dimethyl Sulfoxide, Dimethyl Sulphoxide, Dimethylis Sulfoxidum
Drug: Tezacaftor, Ivacaftor
Brand names:
Symdeko
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 26, 2024
Interaction Details
There were no interactions found between Tezacaftor, Ivacaftor and Dimethylsulfoxide (dmso). This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Dimethylsulfoxide (dmso) Overview
Dimethylsulfoxide (DMSO) is a colorless, odorless liquid that has a number of industrial and medical uses.
In a medicinal sense, DMSO is most commonly used as a topical pain reliever and anti-inflammatory agent. It is applied to the skin as a cream or gel, and is sometimes used to treat conditions such as muscle strains, sprains, and arthritis. DMSO is also an FDA-approved treatment for interstitial cystitis, a condition that causes bladder pain and frequent urination, when given via intravesical instillation (administration directly into the bladder).
DMSO is often added to topical preparations to increase the skin penetration of some medications.
Tezacaftor, Ivacaftor Overview
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The combination of tezacaftor and ivacaftor is used along with ivacaftor to treat certain types of cystic fibrosis (an inborn disease that causes problems with breathing, digestion, and reproduction) in adults and children 6 years of age and older. Tezacaftor and ivacaftor should be used only in people with a certain genetic make-up. Your doctor may order a blood test to help decide if this medication is right for you. Tezacaftor is in a class of medications called cystic fibrosis transmembrane conductance regulator (CFTR) correctors. Ivacaftor is in a class of medications called cystic fibrosis transmembrane conductance regulator (CFTR) potentiators. Both of these medications work by improving the function of a protein in the body to decrease the build-up of thick mucus in the lungs and improve other cystic fibrosis symptoms.
Dimethylsulfoxide (dmso) - More Interactions
Dimethylsulfoxide (dmso) interacts with 326 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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