Equol - Phexxi (Lactic Acid, Citric Acid, Potassium Bitartrate) Interaction

Interaction Details

Lactic Acid, Citric Acid, Potassium Bitartrate is classified as belonging to the following category: Contraceptive Drugs

Theoretically, equol might increase the levels and clinical effects of ethinyl estradiol found in contraceptive drugs.
In vitro research shows that equol inhibits the binding of estradiol to serum proteins. Theoretically, this might increase the concentration of free, bioactive estradiol, thereby increasing the risk of adverse effects from ethinyl estradiol, including headaches, breast tenderness, dysmenorrhea, and weight gain.

Interaction Rating

Likelihood of Occurrence

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists

References

• Martin ME, Haouriqui M, Pelissero C, et al. Interactions between phytoestrogens and human sex steroid binding protein. Life Sci 1996;58:429-36.

Lactic Acid, Citric Acid, Potassium Bitartrate Overview

• The combination of lactic acid, citric acid, and potassium bitartrate is used to prevent pregnancy when used just before vaginal sex in women who can become pregnant. It does not prevent pregnancy when used after vaginal sex. The combination of lactic acid, citric acid, and potassium bitartrate is in a class of medications called non-hormonal contraceptives. It works by lowering the pH of the vagina and reducing sperm motility. Lactic acid, citric acid, and potassium bitartrate may prevent pregnancy, but this medication will not prevent the spread of human immunodeficiency virus (HIV, the virus that causes acquired immunodeficiency syndrome [AIDS]) and other sexually transmitted diseases.

Equol - More Interactions

Equol interacts with 133 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.