Interaction Details

There were no interactions found between Golimumab and Fenugreek. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.


Still looking for more information about combining Golimumab and Fenugreek? Ask Dr. Brian Staiger about it by contacting him directly.

Pharmacist Analysis

Fenugreek is generally considered relatively safe in regard to potential drug interactions.

Nevertheless, interactions are possible between fenugreek and:

  • 'Blood-thinning' drugs
  • Drugs that lower blood pressure
  • Drugs that low blood sugar

Fenugreek contains some components that can prevent blood from clotting. However, there is not enough research to confirm whether the amount of these components present in common fenugreek products can have a clinically significant effect.

Fenugreek may also have an additive effect with blood sugar-lowering medication and blood pressure-lowering medication.

All of these potential interactions are documented individually on our specific drug-herbal interaction pages.

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Fenugreek Overview

Fenugreek Fenugreek (Trigonella foenum-graecum) is a plant native to the Mediterranean region and western Asia. The seeds have a nutty, slightly bitter taste and are commonly used in different types of cuisine. The leaves, which are known as "methi," are used in cooking as well. In addition to its use as a spice and herb, fenugreek has a long history of use in traditional medicine. Some studies have suggested that fenugreek may have potential health benefits, including the ability to lower blood sugar levels in people with diabetes, improve cholesterol levels, and reduce inflammation. It may also have potential benefits for women who are breastfeeding, as it is thought to increase milk production and improve the quality of breast milk.
See More Information Regarding Fenugreek

Golimumab Overview

  • Golimumab injection (Simponi) is used to relieve the symptoms of certain autoimmune disorders (conditions in which the immune system attacks healthy parts of the body and causes pain, swelling, and damage) including:

    • rheumatoid arthritis (condition in which the body attacks its own joints causing pain, swelling, and loss of function) along with methotrexate (Otrexup, Rasuvo, Trexall) in adults,

    • ankylosing spondylitis (condition in which the body attacks the joints of the spine and other areas causing pain and joint damage) in adults,

    • psoriatic arthritis (condition that causes joint pain and swelling and scales on the skin) alone or in combination with methotrexate in adults, and

    • ulcerative colitis (a condition which causes swelling and sores in the lining of the colon [large intestine] and rectum) when other medications and treatments did not help or could not be tolerated.

  • Golimumab injection (Simponi Aria) is also used to relieve the symptoms of certain autoimmune disorders including:

    • rheumatoid arthritis (condition in which the body attacks its own joints causing pain, swelling, and loss of function) along with methotrexate (Otrexup, Rasuvo, Trexall) in adults,

    • ankylosing spondylitis (condition in which the body attacks the joints of the spine and other areas causing pain and joint damage) in adults,

    • psoriatic arthritis (condition that causes joint pain and swelling and scales on the skin) in adults and children 2 years of age and older,

    • polyarticular juvenile idiopathic arthritis (PJIA; a type of childhood arthritis that affects five or more joints during the first six months of the condition, causing pain, swelling, and loss of function) in children 2 years of age and older.

  • Golimumab is in a class of medications called tumor necrosis factor (TNF) inhibitors. It works by blocking the action of TNF, a substance in the body that causes inflammation.

See More Information Regarding Golimumab Injection

Fenugreek - More Interactions

Fenugreek interacts with 374 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.

Major The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur.
Moderate Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur.
Minor Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction.
Unknown No interactions have been reported or no interaction data is currently available.

Return to the main herbal interaction checker page

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Drug descriptions are provided by MedlinePlus.

Ask A Pharmacist About Your Herbal Questions!

Dr. Brian Staiger, PharmD

In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!

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