Garden Cress - Ephedrine, Hydroxyzine, Theophylline Interaction
Herbal: Garden Cress
Also Known As: Lepidium sativum, Berro Hortelano, Cresson Alénois, Cresson de Jardin, Lepidio, Mastuerzo
Drug: Ephedrine, Hydroxyzine, Theophylline
Brand names:
Marax, Ami Rax
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jun 16, 2024
Interaction Details
Ephedrine, Hydroxyzine, Theophylline is classified as belonging to the following category: Theophylline
Theoretically, concurrent use of sildenafil and theophylline might increase levels and adverse effects of theophylline.
Animal research shows that garden cress can increase theophylline concentrations by approximately 37%. It is hypothesized that this increase is due to possible inhibition of cytochrome P450 (CYP) 1A2. So far, this interaction has not been reported in humans.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Al-Jenoobi FI, Ahad A, Mahrous GM, Al-Mohizea AM, AlKharfy KM, Al-Suwayeh SA. Effects of fenugreek, garden cress, and black seed on theophylline pharmacokinetics in beagle dogs. Pharm Biol 2015;53(2):296-300.
Garden Cress Overview
Garden Cress - More Interactions
Garden Cress interacts with 392 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
Unknown | No interactions have been reported or no interaction data is currently available. |
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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Drug descriptions are provided by MedlinePlus.