Goli Apple Cider Vinegar Gummies - Invokamet (Canagliflozin, Metformin) Interaction
Herbal: Goli Apple Cider Vinegar Gummies
Also Known As: Apple cider vinegar, ACV
Drug: Canagliflozin, Metformin
Brand names:
Invokamet
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Feb 11, 2023
Interaction Details
Canagliflozin, Metformin is classified as belonging to the following category: Antidiabetes Drugs
Theoretically, taking apple cider vinegar, which is contained in Goli ACV, with antidiabetes drugs might increase the risk of hypoglycemia (i.e., low blood sugar). Apple cider vinegar might reduce fasting and postprandial blood glucose levels and decrease gastric emptying in people with diabetes, which could theoretically, have additive effects on glucose levels when used with antidiabetes drugs.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
Pharmacist Analysis
Evidence suggests that the risk of experiencing low blood sugar (hypoglycemia) as a result of consuming apple cider vinegar is low.
It appears that the antidiabetic effects of ACV are largely due to it causing a decrease in post-meal glucose and insulin levels, and an increase in feelings of fullness.
Studies have shown that there is a correlation between the amount of acetic acid consumed and glucose and insulin responses, with a higher amount of acetic acid leading to greater reductions in these levels. This may be due to changes in our bodies' sensitivity to glucose and insulin when ACV is consumed.
Additionally, there seems to be a direct relationship between the amount of acetic acid consumed and feelings of fullness, with higher doses resulting in higher levels of satiety (feeling full).
While there still is a theoretical interaction with antidiabetic drugs, there is no published evidence that apple cider vinegar increases the risk of hypoglycemia in humans.
- Dr. Brian Staiger, PharmDGoli Apple Cider Vinegar Gummies Overview
Goli ACV (apple cider vinegar) is a product manufactured by Goli Nutrition. Its main ingredient is apple cider vinegar, which is the fermented juice of crushed apples. The main component of apple cider vinegar is acetic acid, but it also contains small amounts of other organic acids, such as malic acid and citric acid, as well as water and trace minerals and vitamins, such as potassium, magnesium, calcium, and vitamins B1, B2, and B6. Goli ACV, in addition to apple cider vinegar, contains a blend of other ingredients, such as beetroot and pomegranate. It is marketed as a dietary supplement helping to support energy metabolism, a healthy immune system, heart health, and overall well-being. Each gummy contains 500mg of apple cider vinegar.
Goli Apple Cider Vinegar Gummies - More Interactions
Goli Apple Cider Vinegar Gummies interacts with 85 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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