Interaction Details

Digoxin is classified as belonging to the following category: Digoxin (Lanoxin)

It has been suggested that taking apple cider vinegar and digoxin at the same time may increase the likelihood of cardiac toxicity. One case report reported an instance of low potassium levels caused by long-term use of apple cider vinegar has been recorded. Excessive consumption of apple cider vinegar could potentially lead to a drop in potassium levels, heightening the danger of toxicity when taking digoxin.

Interaction Rating

Moderate

Likelihood of Occurrence

Possible

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists

Pharmacist Analysis

The supposed interaction between apple cider vinegar and digoxin, which is commonly mentioned in various online sources, is largely based on a single, isolated case documented in a 1998 issue of the journal Nephron.

The case involved a 28-year-old woman who consumed 250 ml of cider vinegar daily for a period of six years, leading to adverse health effects such as muscle cramps and hypokalemia.

The root cause of her symptoms was identified as excessive intake of acetic acid and its effect on renal excretion of bicarbonate, sodium, and potassium, causing depletion of arterial blood volume and mild hypokalemia.

It's important to note that this was an unusual situation where the individual consumed amounts of ACV far beyond normal levels and the information is only derived from a single case report, which is among the lowest level of evidence in medical literature. Case reports typically describe the experience of a single individual, and while they can provide valuable information about unusual or rare conditions, they cannot be used to establish cause-and-effect relationships or to make generalizations about a population.

Further research is required to validate the findings.

Source: Hypokalemia, Hyperreninemia and Osteoporosis in a Patient Ingesting Large Amounts of Cider Vinegar. Nephron. 1998 Oct;80(2):242-3.

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Goli Apple Cider Vinegar Gummies Overview

Goli Apple Cider Vinegar Gummies Goli ACV (apple cider vinegar) is a product manufactured by Goli Nutrition. Its main ingredient is apple cider vinegar, which is the fermented juice of crushed apples. The main component of apple cider vinegar is acetic acid, but it also contains small amounts of other organic acids, such as malic acid and citric acid, as well as water and trace minerals and vitamins, such as potassium, magnesium, calcium, and vitamins B1, B2, and B6. Goli ACV, in addition to apple cider vinegar, contains a blend of other ingredients, such as beetroot and pomegranate. It is marketed as a dietary supplement helping to support energy metabolism, a healthy immune system, heart health, and overall well-being. Each gummy contains 500mg of apple cider vinegar.
See More Information Regarding Goli Apple Cider Vinegar Gummies

Digoxin Overview

  • Digoxin is used to treat heart failure and abnormal heart rhythms (arrhythmias). It helps the heart work better and it helps control your heart rate.

See More Information Regarding Digoxin

Goli Apple Cider Vinegar Gummies - More Interactions

Goli Apple Cider Vinegar Gummies interacts with 85 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.

Major The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur.
Moderate Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur.
Minor Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction.
Unknown No interactions have been reported or no interaction data is currently available.

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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Drug descriptions are provided by MedlinePlus.

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