1-androsterone Interactions Overview
Check For Interactions With 1-androsterone
1-androsterone
1-Androsterone, also known as 1-DHEA or 1-Andro, is a synthetic prohormone that converts into the steroid 1-testosterone in the body. Prohormones are compounds that are converted into active hormones once ingested, and they are often used by bodybuilders and athletes to enhance muscle growth and performance.
1-Androsterone is believed to have anabolic (muscle-building) and androgenic (male sex hormone-related) effects, similar to testosterone. It's often used as a supplement to potentially increase muscle mass, strength, and overall athletic performance. However, it's important to note that the legality and regulations surrounding prohormones can vary from country to country, and their use may come with risks and potential side effects.
Additional Details
Is 1-Androsterone Safe? Are There Any Warnings?
1-Androsterone, a prohormone found in various supplements targeting athletes and bodybuilders, might cause serious side effects akin to anabolic steroids, including stroke, kidney failure, and liver injury. It is used orally to enhance athletic performance. However, caution is advised due to potential adverse cardiovascular, liver, and kidney effects. Some preliminary research even found unfavorable changes in cholesterol levels, liver enzymes, and kidney function after 4 weeks of use. Pregnant or breastfeeding individuals should avoid it due to potential adverse effects on pregnancy or nursing infants.
How Does 1-Androsterone Work? What Is the Mechanism of Action?
1-Androsterone is a prohormone that converts enzymatically into 1-androstenediol, 1-androstenedione, and 1-testosterone upon ingestion. This conversion is responsible for its effects on body composition and muscle strength. 1-Testosterone, an anabolic steroid twice as potent as natural testosterone, contributes to 1-androsterone's physiological effects. Other byproducts of its metabolism, such as androsterone, epiandrosterone, 3alpha-androstanediol, and 3beta-androstanediol, might also play a role.
Pharmacokinetics
1-Androsterone gets metabolized into its active forms, including 1-testosterone, within the body. Metabolites of 1-androsterone can be detected in urine for up to 7 days after ingestion, including 1-testosterone, 1-androstenedione, and 1-androstenediol.
Interaction Overview
There might be a moderate interaction between 1-androsterone and testosterone, potentially leading to mood disturbances and various adverse effects on cardiovascular, kidney, or liver health. No known interactions with supplements are reported.
Common Side Effects To Watch For
Limited research means a lack of reliable information on side effects, but preliminary studies suggest 1-androsterone might impact cholesterol levels and liver and kidney function.
Are Supplements Standardized?
Currently, there is insufficient information available about the standardization of 1-androsterone in supplements.
What Is 1-Androsterone Typically Used For?
1-Androsterone is used to enhance athletic performance. Some preliminary clinical studies indicate improvements in fat mass reduction and lean body mass increase when taken alongside resistance training. However, more evidence is needed to fully establish its effectiveness in this area.
Drugs that interact with 1-androsterone
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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