Active Hexose Correlated Compound (ahcc) Interactions Overview
Check For Interactions With Active Hexose Correlated Compound (ahcc)
Active Hexose Correlated Compound (ahcc)
Active Hexose Correlated Compound (AHCC) is a proprietary dietary supplement recognized for its potential immune-boosting properties, derived from the mycelia of Basidiomycota mushrooms, including shiitake (Lentinula edodes). Rich in alpha-glucans, AHCC is soluble in water and remains stable, with the additional advantage of enhanced intestinal solubility through micro-coating with candelilla wax. Within Traditional Chinese medicine (TCM), AHCC has found extensive application for various health conditions, particularly in addressing liver damage. Research and traditional usage suggest AHCC may support immune function and mitigate chemotherapy-related side effects, prompting further investigations into its mechanisms and potential benefits.
Additional Details
Is AHCC Safe? Are There Any Warnings?
Active hexose correlated compound (AHCC), extracted from Basidiomycota mushrooms like shiitake, is generally considered safe for oral consumption within appropriate amounts. Extensive clinical trials lasting up to six months have administered daily doses of 4.5-6 grams without indicating any apparent safety concerns. However, caution is advised during pregnancy and lactation due to insufficient data on its safety in these critical periods.
How Does AHCC Work? What Is the Mechanism of Action?
AHCC, an alpha-glucan-rich compound derived from fungi, is believed to modulate biological responses, presenting antioxidant properties and augmenting the activity of natural killer (NK) cells, particularly beneficial for individuals dealing with cancer. The complex mechanism of action encompasses cell cycle regulation, apoptosis induction, immunomodulation, and impacts on specific signaling pathways. Additionally, it displays antimetastatic and antiviral effects.
Comprising approximately 74% oligosaccharides, with 20% being alpha-1,4-glucans, AHCC also contains beta-glucans, glycoproteins, amino acids, lipids, and minerals, contributing to its overall health benefits.
Pharmacokinetics
AHCC's water solubility and micro-coating with candelilla wax ensure optimal absorption in the intestines, enhancing its bioavailability and, consequently, its effectiveness as a dietary supplement.
Interaction Overview
AHCC has the potential to interact with certain drugs, influencing their levels or efficacy. It's crucial to exercise caution, especially with medications metabolized by the CYP2D6 enzyme and immunosuppressants. When combined with drugs metabolized by CYP2D6, AHCC may theoretically increase their levels due to its potential to affect the metabolism of these drugs. Additionally, AHCC may interact with immunosuppressant drugs, potentially reducing their effects. It's highly advisable to consult a healthcare professional before combining AHCC with any medications to ensure its safe usage.
Common Side Effects to Watch For
When taken orally, AHCC may cause mild and manageable side effects like bloating, diarrhea, fatigue, foot cramps, headache, and nausea. Generally, these effects are well-tolerated and not considered severe.
Are Supplements Standardized?
Information regarding the standardization of AHCC is limited, highlighting the necessity for further research and guidelines to establish standardized production and usage protocols for this supplement.
What Is AHCC Typically Used For?
AHCC exhibits promise as a versatile supplement with potential applications in various health conditions. Research suggests its potential efficacy in cancer, diabetes, fungal infections, inflammation, high cholesterol, liver conditions, and immune system enhancement. However, extensive research and clinical trials are necessary to validate and ascertain its effectiveness for these specific purposes.
Drugs that interact with Active Hexose Correlated Compound (ahcc)
Return to the main herbal interaction checker page
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC