Adenosine Interactions Overview

Check For Interactions With Adenosine

Adenosine

Also known as
  • Adenosine
  • Adenosine Monophosphate (AMP)
  • Adenosine-5-monophosphate (A5MP)
  • Adenosine Diphosphate (ADP)
  • Adenosine Triphosphate (ATP)
Adenosine Adenosine, a purine nucleoside, is naturally present in all human cells. The US Food and Drug Administration has approved an injectable form of adenosine as a prescription medication. Adenosine's monophosphate and triphosphate salt forms are occasionally included in supplement products. In supplements, these forms of adenosine are typically used to support energy production and other cellular functions.
There are 47 drugs known to interact with Adenosine

Overview Of Adenosine Drug Interactions

Adenosine, when combined with certain medications, can lead to interactions that should be carefully considered.

When used with Carbamazepine (Tegretol), there is a moderate interaction risk, as both drugs can independently cause heart block, potentially amplifying this effect when used together.

Dipyridamole (Persantine) is another medication that interacts significantly with adenosine, leading to a major interaction risk. Dipyridamole can increase both the therapeutic and toxic effects of adenosine by reducing its metabolism, which can result in dizziness, bradycardia, and syncope when adenosine is administered intravenously to patients taking dipyridamole.

Finally, methylxanthines such as aminophylline, caffeine, and theophylline can also interact with adenosine, albeit with a minor risk. These methylxanthines act as competitive antagonists at adenosine cell surface receptors, potentially blocking its pharmacological effects. It is advised to avoid methylxanthines for 24 hours before cardiac stress tests involving adenosine.

Drugs that interact with Adenosine

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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC