Arnica Drug Interactions, Uses, Effectiveness, Safety & More
What is this page for?
First and foremost: how Arnica interacts with medications. The heart of this page is the interaction list — every drug Arnica is known to interact with, and how serious each one is.
But these pages have grown well beyond that into a full monograph — what Arnica is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy
Check Arnica against your medication
Add one medicationArnica Drug Interactions: The Bottom Line
From the HelloPharmacist Editorial Team · Updated July 2026Based on the available evidence, the overall risk of a clinically significant Arnica drug interaction appears low for most people. None of the listed interactions are rated major, and the single concern behind them rests on lab findings that have not been seen in people.
The one area we watch is anticoagulant and antiplatelet drugs, the blood thinners. Lab studies suggest compounds in arnica flowers could reduce platelet clumping, which in theory could add to a blood thinner's effect on bleeding. That said, this effect has not been reported in humans, and homeopathic arnica preparations are unlikely to cause it at all. Since bleeding risk is closely monitored with these medicines, it still deserves a mention.
Although arnica appears alongside a long list of medications, nearly all of those entries trace back to this one theoretical bleeding concern applied across many individual blood thinners. A large number of listed interactions does not mean each combination is harmful; here, the prediction comes from lab research rather than from problems observed in people taking these medicines together.
Based on HelloPharmacist’s Arnica interaction data and reviewed under our editorial standards.
Drugs that interact with Arnica
122 medications have a known interaction with Arnica, graded by severity. Select any drug for the full evidence-based detail.
Don’t want to scroll the list? Just ask.
Tell us the medications you take and we’ll check each one against Arnica using our pharmacist-reviewed interaction data.
AI summaries are generated from our Arnica interaction data for education only — always confirm with your pharmacist. How we use AI
No drugs match “”.
AbciximabReoPro
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Abciximab interactionAbrocitinibCibinqo
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Abrocitinib interaction Abrocitinib drug page: uses, dosage & side effectsAcenocoumarolSintrom
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Acetaminophen, Ibuprofen interactionAcetylsalicylic AcidEntrophen
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Acetylsalicylic Acid interaction Acetylsalicylic Acid drug page: uses, dosage & side effectsAlteplase, TpaActilyse, Activase
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interaction Aluminum Hydroxide, Aspirin, Magnesium Hydroxide drug page: uses, dosage & side effectsAnacaulase-bcdbNexoBrid
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Anacaulase-bcdb interactionAnagrelideAgrylin
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Anagrelide interaction Anagrelide drug page: uses, dosage & side effectsAnisindioneMiradon
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Anisindione interactionAntithrombin IiiThrombate III
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Antithrombin Iii interactionApixabanEliquis
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Apixaban interaction Apixaban drug page: uses, dosage & side effectsArgatrobanArgatroban
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Argatroban interactionAspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin interaction Aspirin drug page: uses, dosage & side effectsAspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionAspirin, ButalbitalAxotal
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Butalbital interactionAspirin, Butalbital, CaffeineFiorinal
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Butalbital, Caffeine interaction Aspirin, Butalbital, Caffeine drug page: uses, dosage & side effectsAspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionAspirin, Butalbital, Caffeine, PhenacetinMarnal
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Butalbital, Caffeine, Phenacetin interactionAspirin, CaffeineAnacin
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Caffeine interactionAspirin, Caffeine, Codeine PhosphateAnacin w/ Codeine
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Caffeine, Codeine Phosphate interactionAspirin, Caffeine, Dihydrocodeine BitartrateSynalgos DC
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAspirin, Caffeine, Dover's PwdAcedoval, Dovacet
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Caffeine, Dover's Pwd interactionAspirin, Caffeine, HydrocodoneDamason-P
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Caffeine, Hydrocodone interactionAspirin, Caffeine, Isobutylallylbarbituric Acid, PhenacetinLanorinal
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interaction Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin drug page: uses, dosage & side effectsAspirin, Caffeine, OrphenadrineInvagesic, Invagesic Forte, Norgesic, Norgesic Forte, Orphengesic, Orphengesic Forte
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Caffeine, Orphenadrine interactionAspirin, Caffeine, Phenacetin, PropoxypheneMargesic Comp. 65
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Caffeine, Phenacetin, Propoxyphene interactionAspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium OxideBufferin
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide interaction Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide drug page: uses, dosage & side effectsAspirin, CarisoprodolSoma Compound
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Carisoprodol interactionAspirin, Carisoprodol, Codeine PhosphateSoma Compound w/ Codeine
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Carisoprodol, Codeine Phosphate interactionAspirin, Chlorpheniramine, PhenylpropanolamineAlka-Seltzer Plus Cold
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Chlorpheniramine, Phenylpropanolamine interactionAspirin, Citric Acid, Sodium BicarbonateAlka-Seltzer Pain Reliever and Antacid
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Citric Acid, Sodium Bicarbonate interactionAspirin, Codeine PhosphateAspirin w/ Codeine
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Codeine Phosphate interactionAspirin, Codeine Phosphate, MethocarbamolRobaxisal C
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Codeine Phosphate, Methocarbamol interactionAspirin, Codeine Phosphate, PhenobarbitalPhenaphen
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Codeine Phosphate, Phenobarbital interactionAspirin, Diphenhydramine, PhenylpropanolamineAlka Seltzer Plus Night Time Effervescent
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Diphenhydramine, Phenylpropanolamine interactionAspirin, DipyridamoleAggrenox, Asasantin Retard
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Dipyridamole interactionAspirin, Ethoheptazine, MeprobamateEquagesic
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Ethoheptazine, Meprobamate interactionAspirin, HydrocodoneAlor 5 500, Lortab ASA
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Hydrocodone interactionAspirin, MeprobamateMicrainin
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Meprobamate interactionAspirin, MethocarbamolRobaxisal
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Methocarbamol interactionAspirin, OmeprazoleYosprala
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Omeprazole interactionAspirin, OxycodonePercodan
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Oxycodone interactionAspirin, PentazocineTalwin Compound
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Aspirin, Pentazocine interactionBetrixabanBevyxxa
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Betrixaban interactionBivalirudinAngiomax, Angiomax Rtu, Angiox
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Bivalirudin interactionBromfenac SodiumBromsite, Prolensa
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Bromfenac Sodium interaction Bromfenac Sodium drug page: uses, dosage & side effectsCabliviCablivi
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Cablivi interaction Cablivi drug page: uses, dosage & side effectsCangrelorKengreal
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Cangrelor interactionCilostazolPletal
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Cilostazol interaction Cilostazol drug page: uses, dosage & side effectsClopidogrelPlavix
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Clopidogrel interaction Clopidogrel drug page: uses, dosage & side effectsDalteparinFragmin
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Dalteparin interaction Dalteparin drug page: uses, dosage & side effectsDanaparoidOrgaran
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Danaparoid interactionDefibrotide SodiumDefitelio
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Defibrotide Sodium interaction Defibrotide Sodium drug page: uses, dosage & side effectsDiclofenacZorvolex
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Diclofenac interaction Diclofenac drug page: uses, dosage & side effectsDiclofenac PotassiumCambia, Cataflam, Cataflam IR, Voltaren Rapide, Voltarol Rapid
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Diclofenac Potassium interaction Diclofenac Potassium drug page: uses, dosage & side effectsDiclofenac SodiumAcoflam, Acoflam 75 SR, Acoflam Retard, Defenac, Defenac Retard, Defenac SR +40 more
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Diclofenac Sodium interaction Diclofenac Sodium drug page: uses, dosage & side effectsDiclofenac Sodium, MisoprostolArthrotec 50, Arthrotec 75
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Diclofenac Sodium, Misoprostol interactionDiclofenac EpolamineFlector, Licart
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Diclofenac Epolamine interactionDicumarolDicumarol
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Dicumarol interactionDiphenhydramine Hydrochloride, Naproxen SodiumAleve PM
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Diphenhydramine Hydrochloride, Naproxen Sodium interactionDipyridamoleDipyridamole, Persantin, Persantin Injection, Persantin Retard, Persantine
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Dipyridamole interaction Dipyridamole drug page: uses, dosage & side effectsEdoxabanSavaysa
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Edoxaban interaction Edoxaban drug page: uses, dosage & side effectsEffientPrasugrel
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Effient interaction Effient drug page: uses, dosage & side effectsEnoxaparinLovenox
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Enoxaparin interaction Enoxaparin drug page: uses, dosage & side effectsEptifibatideIntegrilin
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Eptifibatide interactionEsomeprazole, NaproxenVimovo
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Esomeprazole, Naproxen interactionFamotidine, IbuprofenDuexis
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Famotidine, Ibuprofen interactionFish Oil TriglyceridesOmegaven
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Fish Oil Triglycerides interactionFondaparinuxArixtra
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Fondaparinux interaction Fondaparinux drug page: uses, dosage & side effectsHeparinHeparin
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Heparin interaction Heparin drug page: uses, dosage & side effectsHydrocodone, IbuprofenVicoprofen
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Hydrocodone, Ibuprofen interactionIbrutinibImbruvica
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Ibrutinib interaction Ibrutinib drug page: uses, dosage & side effectsIbuprofenAdvil, Arthrofen, Brufen, Brufen Retard, Calodor, Calprofen +14 more
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Ibuprofen interaction Ibuprofen drug page: uses, dosage & side effectsIbuprofen LysineNeoProfen
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Ibuprofen Lysine interaction Ibuprofen Lysine drug page: uses, dosage & side effectsIbuprofen, AcetaminophenAdvil Dual Action
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Ibuprofen, Acetaminophen interactionIbuprofen, HydrocodoneIbucodone
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Ibuprofen, Hydrocodone interactionIbuprofen, OxycodoneCombunox
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Ibuprofen, Oxycodone interactionIbuprofen, PseudoephedrineDristan
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Ibuprofen, Pseudoephedrine interactionIcosapent Ethyl (prescription Drug)Vascepa
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Icosapent Ethyl (prescription Drug) interaction Icosapent Ethyl (prescription Drug) drug page: uses, dosage & side effectsIloprostAurlumyn, Ventavis
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Iloprost interaction Iloprost drug page: uses, dosage & side effectsInotersenTegsedi
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Inotersen interactionKetoprofenOrudis, Oruvail Gel, Oruvail Injection, Powergel
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Ketoprofen interaction Ketoprofen drug page: uses, dosage & side effectsLepirudinRefludan
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Lepirudin interactionMinocyclineAcnamino MR, Aknemin, Amzeeq, Arestin Miscrosperes, Dynacin, Minocin +6 more
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Minocycline interaction Minocycline drug page: uses, dosage & side effectsNadroparinFraxiparine
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Nadroparin interactionNaproxenAleve, Anaprox, Anaprox DS, Arthroxen, EC-Naprosyn, Naprelan +7 more
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Naproxen interaction Naproxen drug page: uses, dosage & side effectsNaproxen SodiumMidol Extended Relief
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Naproxen Sodium interactionNaproxen, PseudoephedrineAleve Cold and Sinus
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Naproxen, Pseudoephedrine interactionNaproxen, SumatriptanTreximet
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Naproxen, Sumatriptan interactionNintedanib EsylateOfev
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Nintedanib Esylate interaction Nintedanib Esylate drug page: uses, dosage & side effectsNusinersen SodiumSpinraza
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Nusinersen Sodium interaction Nusinersen Sodium drug page: uses, dosage & side effectsOmega-3 Fatty Acids (prescription Drug)Lovaza
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Omega-3 Fatty Acids (prescription Drug) interactionPazopanibVotrient
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Pazopanib interaction Pazopanib drug page: uses, dosage & side effectsPentoxifyllineTrental
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Pentoxifylline interaction Pentoxifylline drug page: uses, dosage & side effectsPhenprocoumonLiquamar
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Phenprocoumon interactionPiroxicamFeldene, Feldene Gel
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Piroxicam interaction Piroxicam drug page: uses, dosage & side effectsRivaroxabanXarelto
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Rivaroxaban interaction Rivaroxaban drug page: uses, dosage & side effectsSelexipagUptravi
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Selexipag interaction Selexipag drug page: uses, dosage & side effectsSelumetinib SulfateKoselugo
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Selumetinib Sulfate interaction Selumetinib Sulfate drug page: uses, dosage & side effectsSorafenibNexavar
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Sorafenib interaction Sorafenib drug page: uses, dosage & side effectsStreptokinaseKabikinase, Streptase
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Streptokinase interactionTenecteplaseTNKase
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Tenecteplase interactionTicagrelorBrilinta
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Ticagrelor interaction Ticagrelor drug page: uses, dosage & side effectsTiclopidineTiclid, Ticlopidine
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Ticlopidine interaction Ticlopidine drug page: uses, dosage & side effectsTinzaparinInnohep
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Tinzaparin interactionTirofibanAggrastat
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Tirofiban interaction Tirofiban drug page: uses, dosage & side effectsTivozanib HydrochlorideFotivda
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Tivozanib Hydrochloride interaction Tivozanib Hydrochloride drug page: uses, dosage & side effectsTreprostinil
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Treprostinil interaction Treprostinil drug page: uses, dosage & side effectsTreprostinil (iv)Remodulin
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Treprostinil (iv) interaction Treprostinil (iv) drug page: uses, dosage & side effectsTreprostinil (inh)Tyvaso
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Treprostinil (inh) interaction Treprostinil (inh) drug page: uses, dosage & side effectsTreprostinil (oral)Orenitram, Remodulin
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Treprostinil (oral) interaction Treprostinil (oral) drug page: uses, dosage & side effectsUrokinaseAbbokinase
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Urokinase interactionVorapaxarZontivity
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Vorapaxar interaction Vorapaxar drug page: uses, dosage & side effectsWarfarinWarfarin
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Warfarin interaction Warfarin drug page: uses, dosage & side effectsWarfarin SodiumCoumadin, Panwarfin, Sofarin
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Warfarin Sodium interaction Warfarin Sodium drug page: uses, dosage & side effectsAnistreplase, ApsacEminase
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Anistreplase, Apsac interactionDabigatranPradax, Pradaxa
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Dabigatran interaction Dabigatran drug page: uses, dosage & side effectsReteplaseRetevase
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs.
Read the full Arnica + Reteplase interactionWhat Severity, Likelihood & Evidence Mean
Severity — How Serious It Can Be
- Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
- Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
- Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
- No known interaction. Checked against our sources with nothing documented — not the same as proven safety.
Likelihood — How Well It’s Documented
- Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
- Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
- Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Where This Data Comes From
- Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
- Each drug listed above links to the full report for that exact Arnica combination — clinical detail, likelihood, evidence level, and citations.
- Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
The kinds of drugs Arnica affects
Every type of medication (drug category) Arnica is known to interact with. Open any category for the detail — or search your exact drug in the checker above.
Anticoagulant/Antiplatelet Drugs
Theoretically, arnica might have additive effects with anticoagulant and antiplatelet drugs. Homeopathic arnica preparations are unlikely to have this interaction.
In vitro evidence shows that sesquiterpene lactones in arnica flowers can decrease platelet aggregation. However, this effect has not been reported in humans.
Arnica: Uses, Safety & Side Effects
Arnica is a daisy-family plant used mainly in topical and homeopathic products for bruising, muscle soreness, and pain. The evidence is mixed and mostly weak, and undiluted arnica taken by mouth can be toxic, so it should only be used on unbroken skin or in heavily diluted homeopathic forms. Talk to your pharmacist or doctor before using it.

- Scientific name
- Arnica montana
- Family
- Asteraceae
- Part used
- Flowers (and sometimes roots)
- Common forms
- Topical creams, gels, ointments, oils, and homeopathic tablets or pellets
- Bruising
- Muscle soreness
- Joint pain (osteoarthritis)
- Swelling after injury or surgery
- Sprains and minor aches
Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.
Topical and homeopathic forms are generally well tolerated, but undiluted arnica should never be swallowed.
When used orally or topically; avoid using.
Read the full breastfeeding detailPregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Overview
Arnica is a flowering plant in the daisy (Asteraceae) family. It is best known as Arnica montana, a species that grows in the mountains and meadows of Europe, though related arnica species also grow in North America. It produces bright yellow, daisy-like flowers, and these flowers are the part most often used to make medicine.
People have used arnica for centuries in folk and homeopathic medicine. Today it is most commonly found in topical products such as creams, gels, and ointments applied to the skin, as well as in homeopathic tablets or pellets that contain extremely tiny, diluted amounts of the plant.
How it works
Arnica flowers contain compounds called sesquiterpene lactones (such as helenalin), along with flavonoids and volatile oils. In laboratory and animal research, these compounds appear to have anti-inflammatory effects and may affect how the body responds to injury and swelling.
It is important to know that much of this evidence comes from lab and animal studies, not from large human trials. In homeopathic arnica, the plant is diluted so much that little or no measurable active compound usually remains, so any effect is thought to be very different from that of a topical herbal preparation.
Does Arnica work?
How to read these evidence grades
Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.
Possibly Effective Osteoarthritis
Topical arnica gel might reduce osteoarthritis pain.
Also studied for 12 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Acne
Although there is interest in using topical arnica for acne, there is insufficient reliable information about the clinical effects of arnica for this purpose.
Insufficient Reliable Evidence To Rate Bleeding
It is unclear if oral arnica reduces bleeding after surgery.
Insufficient Reliable Evidence To Rate Breast cancer-related hot flashes
Oral homeopathic arnica has only been evaluated in combination with other ingredients; its effect when used alone is unclear.
Insufficient Reliable Evidence To Rate Bruises
Most small clinical trials show that neither topical nor oral arnica reduces postoperative bruising.
Insufficient Reliable Evidence To Rate Diabetic retinopathy
Small clinical studies suggest that oral homeopathic arnica may reduce symptoms of diabetic retinopathy.
Insufficient Reliable Evidence To Rate Dry eye
It is unclear if eye drops containing arnica extract can improve dry eye in children.
Insufficient Reliable Evidence To Rate Exercise-induced muscle soreness
Small studies suggest that oral homeopathic arnica does not reduce muscle soreness after exercise. It is unclear if topical arnica is beneficial.
Insufficient Reliable Evidence To Rate Postoperative pain
Findings related to the use of oral homeopathic arnica are mixed; most studies utilizing a placebo control have yielded negative results.
Insufficient Reliable Evidence To Rate Postoperative recovery
It is unclear if oral homeopathic arnica is beneficial for postoperative recovery.
Insufficient Reliable Evidence To Rate Postoperative swelling
It is unclear if topical arnica reduces swelling after surgery.
Insufficient Reliable Evidence To Rate Stroke
A small study suggests that oral homeopathic arnica does not improve outcomes after stroke.
Insufficient Reliable Evidence To Rate Tooth extraction
It is unclear if oral homeopathic arnica improves symptoms after tooth extraction in adults or children.
Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.
Safety & precautions
Arnica applied to unbroken skin is generally well tolerated for short periods. Homeopathic arnica, because it is so diluted, is also usually considered low risk. However, undiluted arnica taken by mouth can be poisonous and may cause serious effects on the heart, stomach, and nervous system. It should never be swallowed unless it is a properly prepared homeopathic dilution.
Do not apply arnica to broken skin, open wounds, or near the eyes or mouth. People who are allergic to plants in the daisy family (such as ragweed, marigolds, or chamomile) may react to arnica and should avoid it.
For pregnancy and breastfeeding, there is not enough reliable safety information, so it is best to avoid arnica during these times. Always check with your pharmacist or doctor before using it, especially if you have a health condition or take other medicines.
Side effects
When used on the skin, arnica may cause skin irritation, redness, itching, or allergic rashes (contact dermatitis), especially with long use or in people sensitive to daisy-family plants.
Swallowing undiluted arnica can cause serious problems, including nausea, vomiting, stomach pain, dizziness, irregular heartbeat, and in severe cases damage to the heart or other organs. If someone swallows a non-homeopathic arnica product, seek medical help or contact poison control right away.
Arnica: Reported Adverse Effects
Documented safety reports on Arnica from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.
Orally, arnica is unsafe and can cause toxicity. When used in homeopathic amounts, arnica seem to be generally well tolerated. Topically, arnica also seems to be generally well tolerated.
Most Common Adverse Effects:
Orally: Bleeding, gastroenteritis, hypertension, muscle paralysis, nausea and vomiting, shortness of breath.
Topically: Contact dermatitis and irritation.
Serious Adverse Effects (Rare):
Orally: Arrhythmia, coma, multi-organ failure, and death.
Cluster headache Neurologic/CNS
Orally, arnica may cause drowsiness, nervousness, and headache.
Diarrhea Gastrointestinal
Orally, arnica can cause stomach pain, nausea, vomiting, and diarrhea. Homeopathic arnica has been reported to cause dry mouth (30C) and sore tongue (6C). A 24-year-old female presented to the emergency department with palpitations and vomiting 24 hours after ingesting a cup of tea that reportedly contained arnica flowers picked from her local area of mountainous Southern California. The species was not specified in the article and there was no indication by the authors that any testing had been done to confirm the identity of the plant.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- Adkison JD, Bauer DW, Chang T. The effect of topical arnica on muscle pain. Ann Pharmacother 2010;44:1579-84.
- No authors listed. Final report on the safety assessment of Arnica montana extract and Arnica montana. Int.J.Toxicol. 2001;20:1-11.
- Karow JH, Abt HP, Frohling M, and Ackermann H. Efficacy of Arnica montana D4 for healing of wounds after Hallux valgus surgery compared to diclofenac. J Altern Complement Med 2008;14:17-25.
- Stevinson C, Devaraj VS, Fountain-Barber A, et al. Homeopathic arnica for prevention of pain and bruising: randomized placebo-controlled trial in hand surgery. J R Soc Med 2003;96:60-65.
- Canders CP, Stanford SR, Chiem AT. A dangerous cup of tea. Wilderness Environ Med. 2014 Mar;25(1):111-2.
Dry skin Dermatologic
Orally, arnica can cause irritation of mucous membranes. Topically, arnica can cause contact itchiness, dry skin, and rash. Oral lesions resulted in a woman who used a mouthwash incorrectly by not following dilution instructions. The mouthwash was 70% alcohol and contained arnica and oil of peppermint.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- Adkison JD, Bauer DW, Chang T. The effect of topical arnica on muscle pain. Ann Pharmacother 2010;44:1579-84.
- Moghadam BK, Gier R, and Thurlow T. Extensive oral mucosal ulcerations caused by misuse of a commercial mouthwash. Cutis 1999;64:131-134.
Nausea and vomiting Cardiovascular
Orally, arnica can cause tachycardia or a faster heart rate. A 24-year-old female presented to the emergency department with palpitations and vomiting 24 hours after ingesting a cup of tea that reportedly contained arnica flowers picked from her local area of mountainous Southern California. The species was not specified in the article and there was no indication by the authors that any testing had been done to confirm the identity of the plant.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- Adkison JD, Bauer DW, Chang T. The effect of topical arnica on muscle pain. Ann Pharmacother 2010;44:1579-84.
- No authors listed. Final report on the safety assessment of Arnica montana extract and Arnica montana. Int.J.Toxicol. 2001;20:1-11.
- Karow JH, Abt HP, Frohling M, and Ackermann H. Efficacy of Arnica montana D4 for healing of wounds after Hallux valgus surgery compared to diclofenac. J Altern Complement Med 2008;14:17-25.
- Canders CP, Stanford SR, Chiem AT. A dangerous cup of tea. Wilderness Environ Med. 2014 Mar;25(1):111-2.
Neuropathic pain Ocular/Otic
In a case report, accidental intake of a large amount of a homeopathic Arnica-30 resulted in acute vision loss due to bilateral toxic optic neuropathy.
Adverse-effects data: Natural Medicines, Therapeutic Research Center
Dosing
There is no well-established standard dose for arnica. Topical products vary in strength, and homeopathic products are dosed according to the Homeopathic Pharmacopeia of the United States, which uses very high dilutions.
The safest approach is to follow the directions on the product label and use it only as intended. Do not take undiluted arnica by mouth. If you are unsure which product is appropriate or how to use it, ask your pharmacist or doctor for guidance.
Arnica & Pregnancy
Arnica & Breastfeeding
© 2026 Therapeutic Research Center
Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center
References & further reading
The 10 references that drive our Arnica monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Schroder H, Losche W, Strobach H, et al. Helenalin and 11 alpha, 13-dihydrohelenalin, two constituents from Arnica montana L., inhibit human platelet function via thiol-dependent pathways. Thromb Res 1990;57:839-45.
- Adkison JD, Bauer DW, Chang T. The effect of topical arnica on muscle pain. Ann Pharmacother 2010;44:1579-84. PubMed
- No authors listed. Final report on the safety assessment of Arnica montana extract and Arnica montana. Int.J.Toxicol. 2001;20:1-11. DOI
- Karow JH, Abt HP, Frohling M, and Ackermann H. Efficacy of Arnica montana D4 for healing of wounds after Hallux valgus surgery compared to diclofenac. J Altern Complement Med 2008;14:17-25.
- Venkatramani DV, Goel S, Ratra V, et al. Toxic optic neuropathy following ingestion of homeopathic medication Arnica-30. Cutan.Ocul.Toxicol. 2013;32:95-97. PubMed
- Moghadam BK, Gier R, and Thurlow T. Extensive oral mucosal ulcerations caused by misuse of a commercial mouthwash. Cutis 1999;64:131-134.
- Stevinson C, Devaraj VS, Fountain-Barber A, et al. Homeopathic arnica for prevention of pain and bruising: randomized placebo-controlled trial in hand surgery. J R Soc Med 2003;96:60-65. PubMed
- Canders CP, Stanford SR, Chiem AT. A dangerous cup of tea. Wilderness Environ Med. 2014 Mar;25(1):111-2. PubMed
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Brands that make products with Arnica
17 brands in our database make a supplement containing Arnica.
Supplement products with Arnica
45 products in our database contain Arnica. Open any to see its full ingredient list and every drug interaction we check.
Arnica: Common Questions
What is Arnica used for, and does it work?
Does Arnica interact with prescription medications?
How are Arnica interactions rated?
Is it safe to take Arnica with my medications?
Where does this Arnica interaction information come from?
What is Arnica used for?
Is Arnica safe to take by mouth?
Can I use Arnica during pregnancy or while breastfeeding?
Can Arnica cause an allergic reaction?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Products that contain Arnica
A rotating sample of real supplements in our database that list Arnica — open any to see its full ingredients and every drug interaction we check.
- Arnica Flower Powder by TerraVita Premium Collection
- Trauma Drops by Herb Pharm
- Arnica 450 mg 4:1 Extract by TerraVita Premium Collection
- Arnica 4:1 Extract Powder by TerraVita Premium Collection
- Painfree Chocolate Classic Chai Flavor by The Functional Chocolate Company
- Arnica Flower by TerraVita
- Arnica by Herb Pharm
- Arnica by Herbs Etc.
- CBD+13 by T-Relief
- Arnica by L.A. Naturals
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