Autumn Crocus Interactions Overview

Autumn crocus, a perennial herb native to Europe and North Africa, grows from an underground corm and has been known for over 2000 years as a poisonous plant. It contains colchicine and resembles onion, wild garlic, and wild leek, leading to accidental ingestion and colchicine poisoning. Historically, extracts have been used to treat gout and rheumatoid arthritis. However, it is considered unsafe for oral consumption due to its toxicity, causing adverse effects such as agranulocytosis, aplastic anemia, and peripheral neuritis. Topical exposure can cause finger numbness. Due to these risks, it is recommended to use the standardized, FDA-approved prescription form of colchicine for treating conditions like gout and familial Mediterranean fever, under the supervision of a medical professional.