Avocado Soy Unsaponifiables (asu) Interactions Overview

Avocado-soy-unsaponifiables (ASU) are a natural extract made from avocado and soybean oils. They are known for their anti-inflammatory properties and are commonly used to manage symptoms of osteoarthritis. ASU is believed to help reduce pain and improve joint function by inhibiting the breakdown of cartilage and promoting its repair. Additionally, ASU may have a protective effect on joint structures and help reduce the need for nonsteroidal anti-inflammatory drugs (NSAIDs). ASU contains tocopherols, phytosterols, triterpene alcohols, and other constituents, although the exact composition can vary between products. Some products may contain citrostadienol from avocado unsaponifiables, while others may contain brassicasterol, which is not common in avocado or soy. Differences in constituents between products may be due to variations in methods of analysis or preparation. ASU has demonstrated its anti-inflammatory effects by reducing inflammatory cytokines like interleukin-17 and tumor necrosis factor-alpha, while increasing anti-inflammatory cytokines such as interleukin-4 and interleukin-10. It also decreases levels of inflammatory mediators like prostaglandin E2 and metalloproteinase.