Black Alder Interactions Overview

Additional Details

Is Black Alder Safe? Are There Any Warnings?

There is insufficient reliable information available about the safety of black alder. It is important to consult with a healthcare professional before using black alder, especially during pregnancy and lactation due to the limited safety information available.

How Is Black Alder Thought To Work? What Is the Mechanism of Action?

The bark and leaves of black alder contain diarylheptanoid compounds, including hirsutanone. These compounds have been studied for their potential anti-cancer effects in laboratory research. Hirsutanone, specifically isolated from black alder leaves, has demonstrated activity against human colon cancer cells by inducing oxidative stress and DNA strand breaks. However, other diarylheptanoids found in the bark of black alder seem to reduce oxidative stress. The effects of these compounds on cancer cells may depend on their concentration.

Pharmacokinetics

There is insufficient reliable information available about the pharmacokinetics of black alder. More research is needed to understand how black alder is metabolized, absorbed, and eliminated in the body.

Interaction Overview

There are limited known interactions with drugs, supplements, or conditions associated with black alder. However, laboratory research suggests that black alder bark extracts may antagonize the effects of certain chemotherapy drugs, such as cisplatin and doxorubicin. It is important to use caution when combining black alder with these medications until more is known.

Common Side Effects To Watch For

No adverse effects have been reported with the use of black alder. However, due to limited information, it is important to monitor for any unexpected reactions and seek medical attention if necessary.

Standardization & Formulation

There is insufficient reliable information available about the standardization of black alder. The potency and composition of different black alder products may vary. It is important to follow product labeling and consult with healthcare professionals to ensure the use of standardized and appropriate formulations.

What Is Black Alder Typically Used For?

Black alder is traditionally used orally to reduce fever, bleeding, and swelling. It has also been used for various conditions, such as pharyngitis, constipation, rheumatoid arthritis, and cancer. Topically, black alder is used for streptococcal sore throat. However, there is currently insufficient reliable evidence to establish the effectiveness of black alder for these uses. Further research is needed to determine its potential therapeutic benefits.

Drugs that interact with Black Alder