Dulse Interactions Overview
Check For Interactions With Dulse
Dulse
- Palmaria palmata
- Rhodymenia palmata
Dulse, a red seaweed found along the rocky coasts of northern Europe, northern Japan, and North America, is not only a part of various cuisines but is also gaining attention for potential health benefits. While generally considered safe in normal food amounts, caution is advised when considering medicinal use, especially during pregnancy or lactation, as there is limited safety information available. Dulse contains relatively high levels of potassium, iodine, protein, and various polyphenols. Some research suggests it may have anti-inflammatory effects, though its impact on lipid levels is still under investigation.
Additional Details
Is Dulse Safe? Are There Any Warnings?
Dulse, a type of red seaweed, is generally considered safe when consumed as part of food in moderate amounts. It has a long history of being used in various cuisines worldwide. However, there is limited information about the safety of using dulse in medicinal amounts during pregnancy or lactation. It's advisable to avoid excessive amounts beyond those commonly found in foods.
How Is Dulse Thought To Work? What Is the Mechanism of Action?
Dulse, rich in potassium, iodine, and protein, has a diverse composition influenced by factors like growing conditions. Potassium concentrations vary, ranging from 22.2-122 mg/gram dry weight. Iodine levels may depend on factors such as season and water conditions. Dulse also contains proteins like phycoerythrin, polyphenols, fatty acids, and fiber.
In terms of effects, dulse's anti-inflammatory properties, attributed to phenolic constituents, have shown promise in inhibiting neutrophil overstimulation in vitro. However, human studies on inflammatory markers are inconclusive. While dulse is of interest for lipid regulation, research indicates no significant impact on cholesterol levels, and there are even suggestions of potential increases in triglyceride levels.
Pharmacokinetics
After consuming dulse, urinary iodine levels increase, indicating its influence on iodine excretion. The mechanism behind this process involves the absorption and elimination of dulse components by the body.
Interaction Overview
ACE Inhibitors (ACEIs): Dulse, rich in potassium, may interact with ACEIs, potentially affecting potassium levels and the renin-angiotensin-aldosterone system.
Angiotensin Receptor Blockers (ARBs): Similar to ACEIs, dulse's potassium content may interact with ARBs, affecting potassium levels and the renin-angiotensin-aldosterone system.
Digoxin: Due to its potassium richness, dulse may moderately interact with digoxin, possibly increasing the risk of hyperkalemia.
Potassium-Sparing Diuretics: Dulse's potassium content may lead to a mild interaction with potassium-sparing diuretics, potentially increasing the risk of hyperkalemia.
Thyroid Hormone: Dulse's iodine content raises a moderate caution regarding potential interactions with drugs used to treat thyroid dysfunction.
Common Side Effects To Watch For
Orally, dulse appears well-tolerated, with no reported adverse effects. However, a comprehensive safety evaluation is lacking, emphasizing the need for caution, especially when considering medicinal use or in pregnancy and lactation.
Are Supplements Standardized?
There is no established standard dosage for dulse supplements. In clinical trials, it has been provided in various forms, including capsules or incorporated into food like bread. Standardization practices may vary, and caution is advised in the absence of specific dosage recommendations.
What Is Dulse Typically Used For?
Orally, dulse is commonly used for managing hypercholesterolemia and preventing iodine deficiency. As a food, it is consumed fresh or dried, adding a nutritional element to various dishes.
Drugs that interact with Dulse
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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