Ground Ivy Interactions Overview

Check For Interactions With Ground Ivy

Ground Ivy

Also known as
  • Alehoffs
  • Alehoof
  • Catsfoot
  • Cat's-Paw
  • Couronne de Terre
  • Courroie de Terre
  • Courroie de la Saint-Jean
  • Creeping Charlie
  • Gill-Go-By-The-Hedge
  • Gill-Go-Over-The-Ground
  • Glécome Lierre
  • Haymaids
  • Hedgemaids
  • Herbe de Saint-Jean
  • Lierre Terrestre
  • Lizzy-Run-Up-The-Hedge
Ground Ivy Ground ivy is a plant found in Europe, Asia, and North America and traditionally used for gallstones, gastrointestinal complaints, kidney and bladder complaints, menstrual irregularities, upper respiratory complaints, and arthritis.
There are 0 drugs known to interact with Ground Ivy

Additional Details

Is Ground Ivy Safe? Are There Any Warnings?

Ground ivy is considered safe when consumed in amounts found in foods. It is commonly used as a food flavoring. However, there is insufficient information available regarding its safety when used medicinally in oral form. It is advised to avoid using ground ivy during pregnancy due to its potential abortifacient activity. There is also limited information about its safety during lactation, so it is best to avoid its use at this time.

How Is Ground Ivy Thought To Work? What Is the Mechanism of Action?

Ground ivy is a plant that is rich in potassium, iron, phenols, triterpenoids (such as ursolic acid and oleanic acid), polyunsaturated fatty acids, rosmarinic acid, and flavonoids. Research suggests that ground ivy has several potential mechanisms of action:

1. Anticancer effects: Ursolic acid and oleanolic acid found in ground ivy have shown to inhibit the activation of Epstein Barr virus and tumor promotion in animal studies.

2. Anti-inflammatory effects: Ground ivy has been found to inhibit the release of interferon-gamma and lipopolysaccharide-stimulated macrophages, reducing the release of nitric oxide. It also inhibits the production of pro-inflammatory cytokines, IL-12 and TNF-alpha.

3. Anti-lithogenic effects: Animal research indicates that ground ivy extract can reduce the production of gallstones by influencing bile acid composition and exhibiting antioxidant activity.

4. Dermatologic effects: Ground ivy may have potential benefits for UV-induced radiation and pigmentation. It may suppress the inflammatory response and reduce melanin stimulating factors in keratinocytes. However, it does not directly inhibit the melanin producing activities of melanocytes.

Pharmacokinetics

Currently, there is limited information available about the pharmacokinetics of ground ivy. Further research is needed in this area.

Interaction Overview (See Below For Full List)

Ground ivy does not appear to have any known drug interactions. However, there is a theoretical potential for hepatotoxic effects if it is taken along with pennyroyal.

Common Side Effects To Watch For

When applied topically, ground ivy may cause itching and stinging. As for oral use, there is insufficient reliable information available to determine the potential side effects.

Are Supplements Standardized?

There is insufficient reliable information available regarding the standardization of ground ivy supplements. It is important to choose reputable brands that ensure safety and quality.

What Is Ground Ivy Typically Used For?

Traditionally, ground ivy has been used for various purposes including gastrointestinal, kidney, and bladder complaints, menstrual irregularities, upper respiratory issues, arthritis, as well as for skin conditions and wound healing. However, there is limited evidence available to rate its effectiveness for these uses, and further research is needed to establish its therapeutic potential.

Drugs that interact with Ground Ivy

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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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