Verbena Interactions Overview

Additional Details

Is Verbena Safe? Are There Any Warnings?

While the oral consumption of verbena in amounts commonly found in foods is likely safe, there is insufficient reliable information available about the safety of verbena when used orally or topically in medicinal amounts. It is advisable to avoid using vervain during pregnancy and lactation due to the lack of reliable data on its safety in these situations.

How Is Verbena Thought To Work? What Is the Mechanism of Action?

Verbena, specifically its above ground parts, contains various constituents such as verbascoside (acetoside), verbenalin, hastatoside, beta-sitosterol, ursolic acid, oleanolic acid, citral, and other terpenoids and iridoids. These compounds contribute to the medicinal properties of verbena.

The traditionally ascribed antibacterial effects of verbena are attributed to the presence of flavonoids in its extracts, although these effects are relatively weak according to laboratory research. Verbena is also known for its anti-inflammatory properties, as observed in animal studies where verbena extracts demonstrate anti-inflammatory activity.

Pharmacokinetics

Currently, there is insufficient reliable information available about the pharmacokinetics of verbena. More research is needed to understand how the body processes and metabolizes the compounds present in verbena.

Interaction Overview (See Bottom of Page For Full List)

There are potential interactions to consider between verbena and certain drugs or supplements. Notably, verbena may moderately inhibit the activity of cytochrome P450 2B1 (CYP2B1) enzyme. Additionally, polyphenolic compounds from verbena can inhibit iron absorption. It is important to exercise caution and consult with a healthcare professional before combining verbena with any medications or supplements.

Common Side Effects To Watch For

No common side effects of verbena have been reported when used orally in amounts commonly found in foods. However, when used in medicinal amounts and in combination with other herbs, gastrointestinal adverse effects and allergic skin reactions can occur. Topically, verbena can cause contact dermatitis.

Are Supplements Standardized?

Insufficient reliable information is available regarding the standardization of verbena supplements. Standardization is crucial for ensuring consistent quality and efficacy of these products. Further research and standardization efforts are necessary to establish reliable formulations of verbena supplements.

What Is Verbena Typically Used For?

Verbena has a long history of traditional use. Orally, it has been used for various purposes including sore throats, oral and pharyngeal inflammation, respiratory tract diseases, angina, depression, fevers, pain, spasms, digestion disorders, liver and gallbladder diseases, urinary tract disorders, menopausal complaints, and more. Topically, it has been used for poorly healing wounds, abscesses, burns, arthritis, itching, and minor burns. However, the effectiveness of verbena for these conditions lacks sufficient reliable evidence. It is advisable to consult with a healthcare professional for specific health concerns before using verbena or any herbal remedy.

Drugs that interact with Verbena