White Mulberry Interactions Overview

Check For Interactions With White Mulberry

White Mulberry

Also known as
  • Morus alba
  • Chinese White Mulberry
  • Chin Sang
  • Common Mulberry
  • Egyptian Mulberry
  • Mora
  • Moral Blanco
  • Morera Blanca
  • Morin
  • Russian Mulberry
  • Silkworm Mulberry
White Mulberry White mulberry (Morus alba) is a small to medium-sized deciduous tree that is native to China but has been introduced to many other regions of the world. It is widely cultivated for its sweet and juicy berries, which are a rich source of vitamins and minerals. In traditional medicine, white mulberry fruit, leaves, and bark have been used for a variety of purposes, including treating high blood pressure, high cholesterol, and diabetes. It is important to note that white mulberry and black mulberry are different species of the same genus (Morus). White mulberry (Morus alba) is the most common type of mulberry, and it is native to China. Black mulberry (Morus nigra) is native to western Asia and has a darker fruit.
There are 85 drugs known to interact with White Mulberry

What Is White Mulberry Used For?

White mulberry is used medicinally for a variety of purposes, including:

  • Lowering blood sugar levels: White mulberry leaves contain compounds that may help regulate blood sugar levels. These compounds can inhibit the enzymes (such as alpha-glucosidase) that break down carbohydrates into glucose, thus reducing the amount of glucose that enters the bloodstream. 
  • Lowering cholesterol levels: White mulberry leaves contain compounds that may help reduce levels of LDL (bad) cholesterol in the blood. These compounds can bind to bile acids in the intestines, preventing them from being reabsorbed and causing the liver to produce more bile acids from cholesterol, thereby reducing cholesterol levels.
  • Improving heart health: White mulberry contains flavonoids and other compounds that may help improve heart health. These compounds can help reduce inflammation, prevent the oxidation of LDL cholesterol, and lower blood pressure, all of which can contribute to a healthier cardiovascular system.
  • Boosting the immune system: White mulberry fruit contains vitamins C and K, as well as other antioxidants that may help boost the immune system and reduce the risk of infection.
  • Promoting weight loss: Some studies suggest that white mulberry leaf extract may help promote weight loss by reducing the absorption of carbohydrates and preventing the accumulation of fat in the body.

Are White Mulberry Supplements Standardized?

White mulberry supplements are often standardized for their content of a compound called 1-deoxynojirimycin (DNJ). DNJ is believed to be one of the main active compounds in white mulberry leaves that contributes to their potential health benefits, particularly in regulating blood sugar levels.

Most white mulberry supplements are standardized to contain between 1.5% to 5.5% DNJ.

Does White Mulberry Interact With Any Drugs?

Although research is scarce, there are theoretical interactions between white mulberry and drugs used to treat diabetes.

As white mulberry may decrease blood glucose levels, when combined with antidiabetic drugs, there is a risk of blood sugar dropping too low (hypoglycemia).

This interaction is theoretically based on the antidiabetic effects of white mulberry, but more studies are needed to understand if it is clinically significant.

Additionally, studies show that white mulberry may interfere with a protein known as OCT2 (Organic Cation Transporter 2). OCT2 helps move certain types of drugs, such as metformin, out of the body through urine. Preliminaty studies show that white mulberry leaf may slow down the activity of OCT2, causing some drugs to be eliminated more slowly.

Please see the individual drug detail pages for more information.

Drugs that interact with White Mulberry

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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC