Herb & supplement monograph

White Mulberry Drug Interactions, Uses, Effectiveness, Safety & More

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Reviewed by licensed pharmacists Sourced from Natural Medicines

White Mulberry Drug Interactions: The Bottom Line

From the HelloPharmacist Editorial Team · Updated July 2026

Based on the available evidence, the overall risk of a clinically significant White Mulberry drug interaction appears low for most people, though it deserves real attention if you take medicines for blood sugar. None of the listed interactions are rated major, and the concerns behind them rest mostly on theoretical or animal research rather than well-documented human studies.

Interactions deserving the most attention

The interaction that stands out most involves diabetes medications. Clinical research shows white mulberry leaf can lower blood glucose on its own, so combining it with drugs that do the same thing could push blood sugar lower than intended, which matters for anyone whose glucose is closely managed. The other concern involves medicines the kidneys clear through a transporter, such as metformin; animal research suggests white mulberry may slow how quickly the body removes these drugs, which could raise their levels.

What the rest of the list means

The long list of interacting medications largely traces back to those two effects, especially the kidney transporter one, which is predicted rather than proven in people. In other words, most listed combinations reflect what could theoretically happen, not what has been shown to cause meaningful problems in humans.

Check your medications against White Mulberry

Based on HelloPharmacist’s White Mulberry interaction data and reviewed under our editorial standards.

Interaction report

Drugs that interact with White Mulberry

87 medications have a known interaction with White Mulberry, graded by severity. Select any drug for the full evidence-based detail.

2,830 drugs
AcarboseGlucobay, Prandase, Precose
Moderate Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full White Mulberry + Acarbose interaction Acarbose drug page: uses, dosage & side effects
AcetohexamideDymelor
Moderate Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full White Mulberry + Acetohexamide interaction
AlbiglutideTanzeum
Moderate Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full White Mulberry + Albiglutide interaction
AlogliptinNesina
Moderate Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full White Mulberry + Alogliptin interaction Alogliptin drug page: uses, dosage & side effects
Alogliptin, MetforminKazano
Moderate Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full White Mulberry + Alogliptin, Metformin interaction
Alogliptin, PioglitazoneOseni
Moderate Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full White Mulberry + Alogliptin, Pioglitazone interaction
Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
Moderate Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full White Mulberry + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interaction
CanagliflozinInvokana
Moderate Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full White Mulberry + Canagliflozin interaction Canagliflozin drug page: uses, dosage & side effects
Canagliflozin, MetforminInvokamet
Moderate Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full White Mulberry + Canagliflozin, Metformin interaction
Canagliflozin, Metformin HydrochlorideInvokamet XR
Moderate Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full White Mulberry + Canagliflozin, Metformin Hydrochloride interaction
ChlorpropamideChlorpropam, Diabinese
Moderate Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full White Mulberry + Chlorpropamide interaction
DapagliflozinFarxiga
Moderate Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full White Mulberry + Dapagliflozin interaction Dapagliflozin drug page: uses, dosage & side effects
Dapagliflozin Propanediol, MetforminXigduo XR
Moderate Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full White Mulberry + Dapagliflozin Propanediol, Metformin interaction
Dapagliflozin Propanediol, Saxagliptin HydrochlorideQtern
Moderate Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full White Mulberry + Dapagliflozin Propanediol, Saxagliptin Hydrochloride interaction
Dapagliflozin, Metformin Hydrochloride, Saxagliptin HydrochlorideQternmet XR
Moderate Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full White Mulberry + Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interaction
Dasiglucagon HydrochlorideZegalogue
Moderate Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full White Mulberry + Dasiglucagon Hydrochloride interaction Dasiglucagon Hydrochloride drug page: uses, dosage & side effects
DulaglutideTrulicity
Moderate Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full White Mulberry + Dulaglutide interaction Dulaglutide drug page: uses, dosage & side effects
EmpagliflozinJardiance
Moderate Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full White Mulberry + Empagliflozin interaction Empagliflozin drug page: uses, dosage & side effects
Empagliflozin, Linagliptin, Metformin HydrochlorideTrijardy XR
Moderate Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full White Mulberry + Empagliflozin, Linagliptin, Metformin Hydrochloride interaction
Empagliflozin, MetforminSynjardy
Moderate Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full White Mulberry + Empagliflozin, Metformin interaction
Empagliflozin, Metformin HydrochlorideSynjardy XR
Moderate Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full White Mulberry + Empagliflozin, Metformin Hydrochloride interaction
ErtugliflozinSteglatro
Moderate Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full White Mulberry + Ertugliflozin interaction Ertugliflozin drug page: uses, dosage & side effects
Ertugliflozin, Metformin HydrochlorideSegluromet
Moderate Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full White Mulberry + Ertugliflozin, Metformin Hydrochloride interaction
ExenatideBydureon, Byetta
Moderate Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full White Mulberry + Exenatide interaction Exenatide drug page: uses, dosage & side effects
Exenatide SyntheticBydureon BCISE
Moderate Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full White Mulberry + Exenatide Synthetic interaction Exenatide Synthetic drug page: uses, dosage & side effects
GliclazideDiamicron
Moderate Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full White Mulberry + Gliclazide interaction
GlimepirideAmaryl
Moderate Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full White Mulberry + Glimepiride interaction Glimepiride drug page: uses, dosage & side effects
GlipizideGlucotrol, Glucotrol XL
Moderate Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full White Mulberry + Glipizide interaction Glipizide drug page: uses, dosage & side effects
Glipizide, MetforminMetaglip
Moderate Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full White Mulberry + Glipizide, Metformin interaction
GlucagonBaqsimi, Glucagon
Moderate Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full White Mulberry + Glucagon interaction Glucagon drug page: uses, dosage & side effects
Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact White Mulberry combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
The big picture

The kinds of drugs White Mulberry affects

Every type of medication (drug category) White Mulberry is known to interact with. Open any category for the detail — or search your exact drug in the checker above.

All 2 drug categories White Mulberry interacts with
Antidiabetes DrugsOrganic Cation Transporter 2 (oct2) Substrates
Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Clinical research shows that white mulberry leaf can lower blood glucose levels. Advise patients to monitor glucose levels closely.

Likelihood Possible Evidence D
Organic Cation Transporter 2 (Oct2) Substrates

Theoretically, white mulberry leaf might slow the elimination and increase the adverse effects of drugs which are OCT2 substrates.
Animal research shows that coadministration of white mulberry leaf extract with metformin, an OCT2 substrate, slows the renal elimination of metformin via inhibition of OCT2 activity. OCT2 is expressed in the kidneys and is responsible for transporting cationic drugs into tubular epithelial cells in order to be excreted in the urine.

Likelihood Possible Evidence D
Monograph

White Mulberry: Uses, Safety & Side Effects

The bottom line

White mulberry leaf is most studied for helping blunt the rise in blood sugar after meals, but the human evidence is limited and not strong. It is generally well tolerated as a food and tea, but talk to your pharmacist or doctor before using concentrated supplements, especially if you take diabetes medicine.

White Mulberry
Scientific name
Morus alba
Family
Moraceae
Part used
Leaves, fruit (berries), root bark, and twigs
Common forms
Capsules, tablets, leaf tea, powdered leaf extract, dried fruit, liquid extracts
People commonly use it for
  • Blood sugar support
  • High cholesterol
  • Weight management
  • Antioxidant support
  • High blood pressure (traditional use)

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallUse caution

Likely safe as a food, but concentrated supplements are less studied and may lower blood sugar.

PregnancyInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full pregnancy detail
BreastfeedingInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Jump to a section

Overview

White mulberry (Morus alba) is a deciduous tree that is native to China but now grows in many parts of the world, including Europe, the United States, and the Middle East. It has long been important in silk farming because silkworms feed on its leaves.

People eat the sweet white-to-pinkish berries fresh or dried, and the leaves, root bark, and twigs have a long history in traditional Chinese and other folk medicine systems. Today, white mulberry leaf is commonly sold as a capsule, tablet, powder, or tea, often marketed for blood sugar and weight support.

It is worth noting that white mulberry (Morus alba) is a different species from black mulberry (Morus nigra), even though both belong to the same plant genus.

How it works

White mulberry leaf contains a compound called 1-deoxynojirimycin (DNJ), which can block enzymes in the gut that break down complex sugars. By slowing this process, less sugar is absorbed quickly, which may lessen the rise in blood sugar after eating.

The plant also contains flavonoids, polyphenols, and anthocyanins (especially in the fruit) that act as antioxidants in laboratory tests. Researchers have studied these compounds for possible effects on cholesterol and inflammation.

Most of these mechanisms come from test-tube and animal studies, so it is not certain how strongly they apply to people taking supplements.

Effectiveness

Does White Mulberry work?

Evidence overview · 9 uses evaluated
9 Insufficient evidence
How to read these evidence grades

Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.

1EffectiveStrong, consistent evidence it works.
2Likely EffectiveGood evidence, though not yet conclusive.
3Possibly EffectiveSome evidence suggests a benefit.
4Possibly IneffectiveSome evidence it may not help.
5Likely IneffectiveFairly strong evidence it doesn’t help.
6IneffectiveStrong evidence it doesn’t work.
7Insufficient Reliable Evidence to RateToo little research to say either way.

For White Mulberry, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.

Also studied for 9 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Androgenic alopecia
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral white mulberry for androgenic alopecia, there is insufficient reliable evidence about the clinical effects of white mulberry for this purpose.

Insufficient Reliable Evidence To Rate Common cold
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral white mulberry for symptoms of the common cold, including cough and sore throat, there is insufficient reliable evidence about the clinical effects of white mulberry for this purpose.

Insufficient Reliable Evidence To Rate Diabetes
Rating & evidence shown verbatim from Natural Medicines

While research is mixed, most small clinical studies suggest that oral white mulberry does not reduce fasting blood glucose or glycated hemoglobin (HbA1c) in patients with type 2 diabetes; however, it does seem to improve insulin resistance and postprandial blood glucose in these patients.

Insufficient Reliable Evidence To Rate Hyperlipidemia
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral white mulberry is beneficial in patients with hyperlipidemia; the available research has mixed results.

Insufficient Reliable Evidence To Rate Hypertension
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral white mulberry for hypertension, there is insufficient reliable evidence about the clinical effects of white mulberry for this purpose.

Insufficient Reliable Evidence To Rate Impaired glucose tolerance (prediabetes)
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral white mulberry is beneficial in patients with impaired glucose tolerance.

Insufficient Reliable Evidence To Rate Joint pain
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral white mulberry for joint pain, including joint pain associated with osteoarthritis and rheumatoid arthritis (RA), there is insufficient reliable information about the clinical effects of white mulberry for these conditions.

Insufficient Reliable Evidence To Rate Obesity
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral white mulberry can reduce body weight in patients who are obese or overweight.

Insufficient Reliable Evidence To Rate Osteoporosis
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral white mulberry for osteoporosis, there is insufficient reliable evidence about the clinical effects of white mulberry for this purpose.

Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.

Safety & precautions

White mulberry fruit is widely eaten as a food and is generally considered safe in normal food amounts. Leaf supplements and teas appear to be well tolerated by most healthy adults in the short term, but long-term safety has not been well studied.

Because white mulberry may lower blood sugar, people with diabetes or those taking blood-sugar-lowering medicines should use caution and monitor their blood sugar, since levels could drop too low. If you are scheduled for surgery, it may be wise to stop using it beforehand because of possible blood sugar effects.

For pregnancy and breastfeeding, there is not enough reliable safety information. To be safe, avoid medicinal or supplement amounts during these times and stick to ordinary food amounts of the berries only if your doctor agrees.

Always talk with your pharmacist or doctor before starting white mulberry, especially if you have a medical condition or take prescription medicine.

Side effects

White mulberry is usually well tolerated. The most common side effects are mild and digestive, such as bloating, gas, loose stools, nausea, or stomach upset, especially with the leaf or concentrated extracts.

Because it may lower blood sugar, watch for symptoms of low blood sugar such as dizziness, shakiness, sweating, or confusion, particularly if you also take diabetes medicine.

Allergic reactions are possible but uncommon. Stop use and seek medical care if you notice rash, itching, swelling, or trouble breathing.

White Mulberry: Reported Adverse Effects

Documented safety reports on White Mulberry from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.

Orally, white mulberry leaf seems to be well tolerated.

Most Common Adverse Effects:

Orally: Transient bloating, constipation, flatulence, and loose stools.

Reports by condition
Constipation Gastrointestinal

Orally, white mulberry leaf powder 4.6 grams three times daily for 4 weeks was associated with bloating and flatulence in 50% of patients, loose stools in 25% of patients, and constipation in 21% of patients in one clinical study. However, reports of these adverse effects decreased over the course of the 12-week study, suggesting that for some patients the adverse effects may be transient in nature.

  1. Thaipitakwong T, Supasyndh O, Rasmi Y, Aramwit P. A randomized controlled study of dose-finding, efficacy, and safety of mulberry leaves on glycemic profiles in obese persons with borderline diabetes. Complement Ther Med. 2020;49:102292.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

Adverse-effects data: Natural Medicines, Therapeutic Research Center

Dosing

There is no officially established standard dose for white mulberry supplements. Doses used in studies have varied widely depending on the plant part and extract, and there is not enough consistent research to recommend a specific milligram amount.

If you choose to use it, follow the directions on the product label and do not exceed the suggested amount. White mulberry leaf is often taken with or just before a meal when used for blood sugar support.

Because product strength and quality can vary a lot, choose a reputable brand and check with your pharmacist or doctor about whether it is appropriate for you and what dose makes sense.

Pregnancy & Breastfeeding

White Mulberry & Pregnancy

Insufficient reliable information

Insufficient reliable information available; avoid using.

White Mulberry & Breastfeeding

Insufficient reliable information

Insufficient reliable information available; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 6 references that drive our White Mulberry monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Andallu B, Suryakantham V, Lakshmi Srikanthi B, Reddy GK. Effect of mulberry (Morus indica L.) therapy on plasma and erythrocyte membrane lipids in patients with type 2 diabetes. Clin Chim Acta 2001;314:47-53. PubMed
  2. Mudra M, Ercan-Fang N, Zhong L, et al. Influence of mulberry leaf extract on the blood glucose and breath hydrogen response to ingestion of 75 g sucrose by type 2 diabetic and control subjects. Diabetes Care 2007;30:1272-4. PubMed
  3. Kimura T, Nakagawa K, Kubota H, et al. Food-grade mulberry powder enriched with 1-deoxynojirimycin suppresses the elevation of postprandial blood glucose in humans. J Agric Food Chem 2007;55:5869-74. PubMed
  4. Huh HW, Na YG, Bang KH, et al. Extended intake of mulberry leaf extract delayed metformin elimination via inhibiting the organic cation transporter 2. Pharmaceutics. 2020;12(1):49. PubMed
  5. Thaipitakwong T, Supasyndh O, Rasmi Y, Aramwit P. A randomized controlled study of dose-finding, efficacy, and safety of mulberry leaves on glycemic profiles in obese persons with borderline diabetes. Complement Ther Med. 2020;49:102292. PubMed
  6. Thondre PS, Lightowler H, Ahlstrom L, Gallagher A. Mulberry leaf extract improves glycaemic response and insulaemic response to sucrose in healthy subjects: results of a randomized, double blind, placebo-controlled study. Nutr Metab (Lond) 2021;18(1):41. PubMed
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Product directory

Supplement products with White Mulberry

282 products in our database contain White Mulberry. Open any to see its full ingredient list and every drug interaction we check.

Andrographis Plus by Metagenics Tablet Or Pill 90 Tablet(s) View ingredients & interactions Andrographis Plus by Metagenics Tablet Or Pill 30 Tablet(s) View ingredients & interactions Andrographis Plus by Metagenics Tablet Or Pill 30 Tablet(s) View ingredients & interactions Andrographis Plus by Metagenics Tablet Or Pill 90 Tablet(s) View ingredients & interactions ArthroMax by Life Extension Capsule 60 Vegetarian Capsule(s) View ingredients & interactions ArthroMax Elite by Life Extension Tablet Or Pill 30 Vegetarian Tablet(s) View ingredients & interactions Astra Isatis by Health Concerns Capsule 90 Capsule(s) View ingredients & interactions Astra Isatis by Health Concerns Capsule 270 Capsule(s) View ingredients & interactions Astra Isatis by Health Concerns Capsule 90 Capsule(s) View ingredients & interactions Attack 1 by Pacific BioLogic Capsule 90 Vegetarian Capsule(s) View ingredients & interactions Attack 2 by Pacific BioLogic Capsule 90 Vegetarian Capsule(s) View ingredients & interactions Autumn Rain Teapills by Plum Flower Tablet Or Pill 1.2 oz. · 33 Gram(s) · 200 Pill(s) View ingredients & interactions Autumn Rain Teapills by Plum Flower Tablet Or Pill 1.2 Ounce(s) · 33 Gram(s) · 200 Pill(s) View ingredients & interactions Balance Blood Sugar by ANTIAGING Institute of California Capsule 60 Vegetarian Capsule(s) View ingredients & interactions Biotae by Merry Clinic Tablet Or Pill 150 Tablet(s) View ingredients & interactions Blood Sugar by Healths Harmony Capsule 120 Capsule(s) View ingredients & interactions Blood Sugar by Dr. Tobias Capsule 90 Capsule(s) View ingredients & interactions Blood Sugar by Healths Harmony Capsule 120 Capsule(s) View ingredients & interactions Blood Sugar by Healths Harmony Capsule 60 Capsule(s) View ingredients & interactions Blood Sugar by Healths Harmony Capsule 60 Capsule(s) View ingredients & interactions Blood Sugar 365 by Arazo Nutrition Capsule 120 Capsule(s) View ingredients & interactions Blood Sugar Balance by SkinnyBean Capsule 60 Capsule(s) View ingredients & interactions Blood Sugar Formula by Rise-N-Shine Capsule 60 Capsule(s) View ingredients & interactions Blood Sugar Formula by SigmaCeutical Capsule 60 Capsule(s) View ingredients & interactions
Pharmacist Counseling Corner

White Mulberry: Common Questions

What is White Mulberry used for, and does it work?
People use White Mulberry for a range of reasons, but according to the Natural Medicines database the current clinical evidence is insufficient to confirm it works for the specific conditions it has been studied for. See the graded list on this page, and talk to your pharmacist or doctor before relying on it for any condition.
Does White Mulberry interact with prescription medications?
Yes. We list 87 medications with a known interaction with White Mulberry. Use the checker above to see how White Mulberry interacts with a specific drug.
How are White Mulberry interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take White Mulberry with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this White Mulberry interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
What is White Mulberry used for?
It is most commonly used to help support healthy blood sugar after meals, and people also take it for cholesterol, weight management, and blood pressure. The strongest interest is in blood sugar, but the human evidence is still limited.
Is White Mulberry safe to take?
The fruit is a common food and is generally safe, and leaf supplements appear well tolerated short-term in healthy adults. Use caution if you have diabetes or take blood-sugar-lowering medicine, and check with your pharmacist first.
Can I take White Mulberry while pregnant or breastfeeding?
There is not enough reliable safety information, so it is best to avoid medicinal or supplement amounts during pregnancy and breastfeeding. Talk to your doctor before using it.
Does White Mulberry help with weight loss?
Some lab and animal research and a few small human studies suggest possible effects, but the evidence is weak and not convincing. It should not be relied on as a weight-loss treatment.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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