Huperzine A - Razadyne ER (Galantamine Extended Release) Interaction
Herbal: Huperzine A
Also Known As: HupA, Huperzina A, Huperzine, Huperzine-A, Selagine, Sélagine
Drug: Galantamine Extended Release
Brand names:
Razadyne ER
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jul 22, 2023
Interaction Details
Galantamine Extended Release is classified as belonging to the following category: Cholinergic Drugs
Theoretically, concurrent use of huperzine A with cholinergic drugs might increase the effects and side effects of these medications.
Huperzine A can inhibit acetylcholinesterase (AChE) and might cause cumulative effects if used with cholinergic drugs.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Skolnick AA. Old Chinese herbal medicine used for fever yields possible new Alzheimer Disease therapy. JAMA 1997;277:776.
Huperzine A Overview
Huperzine A is a chemical compound extracted from the Chinese herb Huperzia serrata (toothed clubmoss). It is a type of acetylcholinesterase inhibitor that prevents the breakdown of the neurotransmitter acetylcholine. Acetylcholine is involved in a variety of processes, including learning and memory. Based on this mechanism of action, Huperzine A is sometimes marketed as a dietary supplement, with claims that it can improve cognitive function and treat conditions such as Alzheimer's disease and dementia.
Huperzine A - More Interactions
Huperzine A interacts with 216 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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