Kaolin - Quinidine Interaction
Herbal: Kaolin
Also Known As: Hydrated aluminum silicate, White Bole
Drug: Quinidine
Brand names:
Quinaglute Duratabs, Quinaglute, Duraquin, Cardioquin, Cin-Quin, Quinora, Lin-Qin, Quinova, Quinidex Extentabs
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jul 22, 2023
Interaction Details
Quinidine is classified as belonging to the following category: Quinidine
Preliminary evidence suggests that kaolin might decrease quinidine absorption. To avoid a potential interaction, separate quinidine and kaolin doses by at least 3 hours.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Bucci AJ, Myre SA, Tan HS, Shenouda LS. In vitro interaction of quinidine with kaolin and pectin. J Pharm Sci 1981;70:999-1002.
- Electronic Code of Federal Regulations. Title 21. Part 335 - Antidiarrheal drug products for over-the-counter human use. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=335.50
Kaolin Overview
Kaolin is a soft, white, clay mineral composed of aluminum silicate. It is also known as china clay. Kaolin is widely used in a variety of industries, including paper manufacturing, ceramics, and pharmaceuticals. In the pharmaceutical industry, it is used as an ingredient in some antidiarrheal medications due to its ability to absorb water and prevent fluid loss. Kaolin is also used in cosmetics as a gentle, natural ingredient in facial masks and other skincare products due to its absorbent properties. It has also traditionally been used to treat nausea, abdominal pain, diarrhea, and excessive salivation.
Quinidine Overview
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Quinidine is used to treat certain types of irregular heartbeats. Quinidine is in a class of medications called antiarrhythmic medications. It works by making your heart more resistant to abnormal activity.
Kaolin - More Interactions
Kaolin interacts with 6 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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