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Quinidine

Quinidine is an antiarrhythmic medicine (it steadies the heart's rhythm) used for atrial fibrillation/flutter and life-threatening ventricular arrhythmias, and, in the sulfate tablet, for life-threatening malaria.

Brand names CardioquinCin-QuinDuraquinQuinactQuinaglute +5 more
Drug classes Antiarrhythmic
Rx Forms 2
Dr. Brian Staiger, PharmD, BCPS
Reviewed by Last reviewed Jul 10, 2026 Content updated Oct 2, 2026
🧬 Where this information comes from Click to expand

The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 4 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →

✓No current FDA shortage listed · checked Oct 7, 2026
Quinidine at a glance The quick version — the full detail is in the Patient Information Guide below.
Dr. Brian Staiger, PharmD, BCPS
The Pharmacist’s Take By · Clinical pharmacist · Written

Quinidine is an older antiarrhythmic, a heart-rhythm medicine that slows the heart's electrical signals and makes heart cells slower to re-fire, used for atrial fibrillation/flutter and life-threatening ventricular arrhythmias; it has been on the U.S. market since about 1950, is available as a generic, and is now usually reserved for when other options fall short. Many people find it hard on the stomach, with diarrhea, nausea and heartburn the effects most often noticed. Its boxed warning links it to a higher risk of death, especially with structural heart disease, and it can trigger torsades de pointes, a dangerous rhythm, so get help right away for fainting or a racing, irregular heartbeat.

Clinical pearls

  • Ringing in the ears, blurred vision, vertigo or confusion can signal quinidine toxicity (cinchonism), so call your prescriber promptly.
  • Quinidine can roughly double digoxin levels and strengthen warfarin, so tell whoever manages those medicines when you start it.
  • Food boosts absorption, so take it the same way with meals each time, skip grapefruit juice, and avoid big swings in salt.
  • The extended-release gluconate tablet can be broken in half but should never be crushed or chewed.
How we write & review this content — our editorial policy →
⚠️ FDA Boxed Warning — the FDA’s strongest safety alert ▾

Antiarrhythmic drugs like quinidine have been linked to a higher risk of death, especially in people with structural heart disease.

In studies of people using quinidine to prevent atrial fibrillation or flutter from coming back, deaths were more than three times as high as with placebo. In people with non-life-threatening ventricular arrhythmias, deaths were consistently higher than with other antiarrhythmic drugs. Discuss this risk with your prescriber.

Read the full warning on DailyMed →
How you get itPrescription only
Comes asExtended-release tablet, Tablet
Earliest FDA record1950
Companies listing it with the FDA4
FDA label last updatedFeb 1, 2018
FDA’s strongest warning (boxed)Yes, read the warning

Patient information guide A plain-language walkthrough of Quinidine, written from its FDA label.

What Quinidine is used for

▾

Quinidine is used for heart rhythm problems and, in one form, malaria.

  • Restoring normal rhythm in symptomatic atrial fibrillation/flutter when rate control has not worked (Quinidine Sulfate tablets and Quinidine Gluconate extended-release tablets).
  • Reducing relapses of atrial fibrillation/flutter in some high-risk patients (both products).
  • Suppressing recurrent, life-threatening ventricular arrhythmias such as sustained ventricular tachycardia (both products).
  • Treating life-threatening P. falciparum malaria (Quinidine Sulfate tablets only).

How Quinidine works

▾

In the heart, quinidine blocks sodium channels, which slows electrical conduction and makes heart tissue slower to fire again. This can interrupt or prevent abnormal rhythms like atrial fibrillation and flutter. In malaria, it acts on the parasite inside red blood cells.

Quinidine dosage

▾

Quinidine is taken by mouth several times a day, on a schedule your prescriber sets. Starting or adjusting treatment may happen where your heart can be monitored.

  • Quinidine Gluconate extended-release tablets can be split in half but must not be crushed or chewed.
  • Quinidine Sulfate tablets for malaria are part of a regimen built around Quinidine Gluconate Injection.
  • Food increases absorption, and grapefruit juice should be avoided.

Dosing details from the FDA-approved label

From the Quinidine prescribing information (“Dosage and Administration”). Doses are set by your prescriber for your product, condition, kidney function and age — never change a dose on your own.

  • Conversion of atrial fibrillation/flutter to sinus rhythm (quinidine gluconate extended-release tablets)
    • In one reported regimen, two tablets (648 mg
    • 403 mg of quinidine base) every eight hours
    • If no conversion after 3 or 4 doses, the dose is cautiously increased
    • In another regimen, one tablet (324 mg
    • 202 mg of quinidine base) every eight hours for two days
    • Then two tablets every twelve hours for two days
    • And finally two tablets every eight hours for up t
    • Discontinue if QRS widens to 130% of pre-treatment duration, QTc widens to 130% and is then longer than 500 ms, P waves disappear, or significant tachycardia, symptomatic bradycardia or hypotension develops; tablets may be broken in half but not crushed or chewed
  • Reduction in the frequency of relapse into atrial fibrillation/flutter (quinidine gluconate extended-release tablets)
    • Begin with one tablet (324 mg
    • 202 mg of quinidine base) every eight or twelve hours
    • If well tolerated, serum level well within the therapeutic range and time between episodes not satisfactorily increased, the dose may be cautiously raised
    • Reduce total daily dosage if QRS widens to 130% of pre-treatment duration, QTc widens to 130% and is then longer than 500 ms, P waves disappear, or significant tachycardia, symptomatic bradycardia or hypotension develops
  • Suppression of life-threatening ventricular arrhythmias (quinidine gluconate extended-release tablets)
    • Dosing regimens have not been adequately studied
    • Described regimens have generally been similar to the regimen for prophylaxis of symptomatic atrial fibrillation/flutter
    • Where possible, guide therapy by programmed electrical stimulation and/or Holter monitoring with exercise
  • Treatment of P. falciparum malaria (quinidine sulfate tablets)
    • Tablets are used in one of the approved regimens for life-threatening P. falciparum malaria
    • The central component is Quinidine Gluconate Injection, described in its package insert
  • Conversion of atrial fibrillation/flutter to sinus rhythm (quinidine sulfate tablets)
    • In one reported regimen, two tablets (400 mg
    • 332 mg of quinidine base) every six hours
    • If no conversion after 4 or 5 doses, the dose is cautiously increased
    • Discontinue if QRS widens to 130% of pre-treatment duration, QTc widens to 130% and is then longer than 500 ms, P waves disappear, or significant tachycardia, symptomatic bradycardia or hypotension develops
  • Reduction of frequency of relapse into atrial fibrillation/flutter (quinidine sulfate tablets)
    • Begin with 200 mg (equivalent to 166 mg of quinidine base) every six hours
    • If well tolerated, serum level well within the therapeutic range and time between episodes not satisfactorily increased, the dose may be cautiously raised
    • Reduce total daily dosage if QRS widens to 130% of pretreatment duration, QTc widens to 130% and is then longer than 500 ms, P waves disappear, or significant tachycardia, symptomatic bradycardia or hypotension develops
  • Suppression of ventricular arrhythmias (quinidine sulfate tablets)
    • Dosing regimens for life-threatening ventricular arrhythmias have not been adequately studied
    • Described regimens have generally been similar to the regimen for prophylaxis of symptomatic atrial fibrillation/flutter
    • Where possible, guide therapy by programmed electrical stimulation and/or Holter monitoring with exercise
Read the label’s full dosing text

DOSAGE AND ADMINISTRATION The dose of quinidine delivered by quinidine gluconate extended-release tablets may be titrated by breaking a tablet in half. If tablets are crushed or chewed, their extended-release properties will be lost. The dosage of quinidine varies considerably depending upon the general condition and the cardiovascular state of the patient. Conversion of atrial fibrillation/flutter to sinus rhythm Especially in patients with known structural heart disease or other risk factors for toxicity, initiation or dose-adjustment of treatment with quinidine gluconate should generally be performed in a setting where facilities and personnel for monitoring and resuscitation are continuously available. Patients with symptomatic atrial fibrillation/flutter should be treated with quinidine gluconate only after ventricular rate control (e.g., with digitalis or β-blockers) has failed to provide satisfactory control of symptoms. Adequate trials have not identified an optimal regimen of quinidine gluconate for conversion of atrial fibrillation/flutter to sinus rhythm. In one reported regimen, the patient first receives two tablets (648 mg; 403 mg of quinidine base) of quinidine gluconate every eight hours. If this regimen has not resulted in conversion after 3 or 4 doses, then the dose is cautiously increased. If, at any point during administration, the QRS complex widens to 130% of its pre-treatment duration; the QT c interval widens to 130% of its pre-treatment duration and is then longer than 500 ms; P waves disappear; or the patient develops significant tachycardia, symptomatic bradycardia, or hypotension, then quinidine gluconate is discontinued, and other means of conversion (e.g., direct-current cardioversion) are considered. In another regimen sometimes used, the patient receives one tablet (324 mg; 202 mg of quinidine base) every eight hours for two days; then two tablets every twelve hours for two days; and finally two tablets every eight hours for up to four days. The four-day stretch may come at one of the lower doses if, in the judgment of the physician, the lower dose is the highest one that will be tolerated. The criteria for discontinuation of treatment with quinidine gluconate are the same as in the other regimen.

Excerpted — the section continues on the label. Read the full Dosage and Administration section on DailyMed →

Quinidine side effects

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Stomach upset is the most commonly reported problem.

Common side effects

  • Diarrhea
  • Nausea and vomiting
  • Heartburn or esophagitis
  • Fever
  • Rash
  • Dizziness
  • Headache
  • Weakness

When to get medical help

  • Fainting, a racing or irregular heartbeat, or a very slow heartbeat
  • Ringing in the ears, hearing loss, vertigo, blurred or double vision, confusion (possible signs of cinchonism, quinidine toxicity)
  • Unusual bruising or bleeding, which can be a sign of low platelets
  • Yellowing of the skin or eyes, or other signs of liver problems, especially in the first weeks
  • Hives, swelling, wheezing, or severe rash (allergic or immune reactions)
  • Persistent vomiting or diarrhea, which can be early signs of toxicity

Quinidine warnings and precautions

▾
  • Higher risk of death seen with antiarrhythmic drugs including quinidine, especially with structural heart disease.
  • It can prolong the QT interval and cause torsades de pointes, a life-threatening rhythm.
  • It may rarely cause a very fast ventricular rate in atrial fibrillation/flutter.
  • It can cause severe slow heartbeat in sick sinus syndrome.
  • It can cause immune-mediated low platelets; anyone with quinidine-dependent antibodies should not take it again.
  • Kidney or liver problems and heart failure can cause toxicity if the dose is not reduced.
  • Liver inflammation has been reported, mostly in the first few weeks.

Quinidine interactions

▾

Quinidine interacts with many medicines and some foods.

  • Digoxin: levels may double.
  • Warfarin: stronger blood-thinning effect.
  • Diltiazem, verapamil, amiodarone, cimetidine, ketoconazole: raise quinidine levels.
  • Phenobarbital, phenytoin, rifampin: speed its breakdown.
  • Thiazide diuretics, sodium bicarbonate, carbonic-anhydrase inhibitors: slow its removal.
  • CYP2D6-dependent drugs such as codeine and hydrocodone: effects can change.
  • Grapefruit juice: avoid.

Interactions listed in the FDA-approved label

From the Quinidine prescribing information (“Drug Interactions”): what the manufacturer studied or reported to the FDA.

  • Diltiazem: Diltiazem significantly decreases the clearance and increases the half-life of quinidine, but quinidine does not alter the kinetics of diltiazem.
  • Urine-alkalinizing drugs (carbonic-anhydrase inhibitors, sodium bicarbonate, thiazide diuretics): They reduce renal elimination of quinidine.
  • Amiodarone or cimetidine: Quinidine levels are increased by coadministration.
  • Phenobarbital, phenytoin, rifampin: Hepatic elimination of quinidine may be accelerated by these inducers of cytochrome P450 IIIA4.
  • Verapamil: Hepatic clearance of quinidine is significantly reduced, with increases in serum levels and half-life; hypotension from additive peripheral α-blockade is sometimes reported.
  • Grapefruit juice: Grapefruit juice inhibits P450 3A4-mediated metabolism of quinidine to 3-hydroxyquinidine. Grapefruit juice should be avoided.
  • Digoxin: Quinidine slows elimination of digoxin and reduces its apparent volume of distribution, so serum digoxin levels may be as much as doubled. Digoxin doses usually need to be reduced.
  • Warfarin: Quinidine potentiates the anticoagulatory action of warfarin. The anticoagulant dosage may need to be reduced.
  • Drugs metabolized by cytochrome P450 IID6 (e.g., mexiletine, some phenothiazines, most polycyclic antidepressants, codeine, hydrocodone): Therapeutic quinidine levels inhibit P450 IID6, effectively converting extensive metabolizers into poor metabolizers. Caution must be exercised whenever quinidine is prescribed together with drugs metabolized by cytochrome P450 IID6.
  • Neuromuscular blocking agents (succinylcholine, decamethonium, d-tubocurarine, pancuronium): Quinidine potentiates the actions of depolarizing and non-depolarizing neuromuscular blocking agents.
Read the label’s full interactions text

Drug and Diet Interactions Altered pharmacokinetics of quinidine: Diltiazem significantly decreases the clearance and increases the t 1/2 of quinidine, but quinidine does not alter the kinetics of diltiazem. Drugs that alkalinize the urine ( carbonic-anhydrase inhibitors, sodium bicarbonate, thiazide diuretics ) reduce renal elimination of quinidine. By pharmacokinetic mechanisms that are not well understood, quinidine levels are increased by coadministration of amiodarone or cimetidine . Very rarely, and again by mechanisms not understood, quinidine levels are decreased by coadministration of nifedipine . Hepatic elimination of quinidine may be accelerated by coadministration of drugs ( phenobarbital, phenytoin, rifampin ) that induce production of cytochrome P450 IIIA4 . Perhaps because of competition for the P450 IIIA4 metabolic pathway, quinidine levels rise when ketoconazole is coadministered. Coadministration of propranolol usually does not affect quinidine pharmacokinetics, but in some studies the β-blocker appeared to cause increases in the peak serum levels of quinidine, decreases in quinidine's volume of distribution, and decreases in total quinidine clearance. The effects (if any) of coadministration of other β-blockers on quinidine pharmacokinetics have not been adequately studied. Hepatic clearance of quinidine is significantly reduced during coadministration of verapamil , with corresponding increases in serum levels and half-life. Grapefruit juice: Grapefruit juice inhibits P450 3A4-mediated metabolism of quinidine to 3-hydroxyquinidine. Although the clinical significance of this interaction is unknown, grapefruit juice should be avoided. Dietary salt: The rate and extent of quinidine absorption may be affected by changes in dietary salt intake; a decrease in dietary salt intake may lead to an increase in plasma quinidine concentrations.

Excerpted — the section continues on the label. Read the full Drug Interactions section on DailyMed →

Not a complete list. The label covers the interactions the manufacturer studied or reported, and our own interaction database does not cover every medicine either. Bring your full medication list, including vitamins and herbal products, to your pharmacist.

🌿207 supplements and herbs with documented Quinidine interactions, ranked by severity Check Quinidine against a supplement or herb →

Before taking Quinidine

▾
  • Allergy to quinidine, or prior low platelets from quinidine or quinine.
  • Complete heart block or pacemaker-dependent rhythm without a working pacemaker.
  • Myasthenia gravis or similar conditions.
  • Long-QT syndrome, past torsades, slow heartbeat, or low potassium or magnesium.
  • Heart failure, sick sinus syndrome, or kidney or liver disease.

Quinidine overdose

▾

Overdose can cause dangerous heart rhythms and low blood pressure. It may also cause vomiting, diarrhea, ringing in the ears, vision changes, confusion, and delirium. Deaths have been reported, including in a toddler. Call a poison control center or seek emergency care right away.

What Quinidine does in the body

▾

Quinidine slows electrical conduction and reduces automaticity in the heart. It lengthens the refractory period (the pause before heart cells can fire again). It prolongs the QT interval in a dose-related way. It also has anticholinergic, vasodilating, and heart-weakening (negative inotropic) effects.

How your body processes Quinidine

▾

Quinidine gluconate is about 70 to 80% absorbed, with peak levels in 3 to 5 hours. Food increases absorption. The half-life is 6 to 8 hours in adults and 3 to 4 hours in children. The liver breaks most of it down using CYP3A4, and one metabolite, 3-hydroxyquinidine, is also active. Some is cleared unchanged by the kidneys, more when urine is acidic.

How to store Quinidine

▾

Store at 20° to 25°C (68° to 77°F). DISPENSE IN TIGHT, LIGHT-RESISTANT CONTAINER.

Written from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →

207

Supplements & herbs that interact with Quinidine

207 supplements and herbal products have documented interactions with Quinidine in the licensed clinical database we use. Most are manageable — but your pharmacist should know about everything you take, including vitamins and herbals.

Severity mix
  • Major · 15
  • Moderate · 157
  • Minor · 35
ACTIVATED CHARCOAL Major AMERICAN HELLEBORE Major ARSENIC Major BEER Major CESIUM Major CINCHONA Major EPHEDRA Major GRAPEFRUIT Major +199 more
Every supplement checked against Quinidine — ranked by severity The full interaction hub: 15 major · 157 moderate · 35 minor · every one linked to its full report. Check Quinidine against your exact supplements

Educational information from a licensed clinical database (Natural Medicines) — see our data sources & update cadence. Not medical advice: an interaction being documented does not mean it will happen to you; do not start or stop medications or supplements without professional guidance.

Quinidine: pharmacist answers to common questions

Quick, plain-English answers to the questions patients ask most about Quinidine — the kind of thing our pharmacy team would talk through with you at the counter.

What is quinidine for?

▾
It treats certain heart rhythm problems, like atrial fibrillation/flutter and life-threatening ventricular arrhythmias. The sulfate tablet is also used for life-threatening falciparum malaria. It's usually reserved for cases where other options haven't worked well enough.

How should I take it?

▾
Take it by mouth exactly as your prescriber directs. If you have the Quinidine Gluconate extended-release tablet, don't crush or chew it, though it can be split in half if told to. Avoid grapefruit juice.

What side effects should I expect?

▾
Stomach upset is most common, especially diarrhea, nausea, vomiting and heartburn. Some people get rash, fever, dizziness or headache. Call your doctor if you have ringing in the ears, vision changes, confusion, or fainting.

Is quinidine safe for my heart?

▾
It can help control rhythm, but it also carries a boxed warning for a higher risk of death, especially with structural heart disease. It can also cause dangerous rhythm changes. That's why your doctor may monitor you closely, especially when starting.

Do I need to worry about other medicines?

▾
Yes, quinidine interacts with many drugs. Digoxin and warfarin are important ones, because quinidine can raise their effects. Always tell me or your doctor before starting anything new, including over-the-counter products.

Is Quinidine available over the counter?

▾
No. Quinidine is a prescription medicine: every Quinidine product listed with the FDA is prescription only, so it is not sold over the counter. Your prescriber decides whether it is appropriate for you, and your pharmacist dispenses it.

When was Quinidine first available?

▾
The earliest FDA record we hold for Quinidine is from 1950: its first approval in Drugs@FDA or its earliest product listing in the NDC Directory, whichever is older. Many older medicines were in use before their first formal FDA approval, so this is the earliest date on record, not necessarily when Quinidine was first used.

Who makes Quinidine?

▾
4 companies currently list Quinidine products in the FDA's NDC Directory, including Epic Pharma, Llc, Eywa Pharma Inc, Golden State Medical Supply. That count includes repackagers and distributors as well as manufacturers (companies that sell only the raw ingredient are not counted), so fewer companies actually make it; the label on your bottle names the one that supplied yours.

Answers drafted from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →

More about Quinidine on HelloPharmacist

📊Quinidine supplement interactions207 checked — ranked by severity 🌿Drug & Supplement CheckerQuinidine vs. vitamins & herbs 💬Ask a PharmacistFree answer, usually < 24h 🔎NDC & pricing lookupFind Quinidine NDCs & costs 🅰️Browse Drugs A–ZLook up any medication
Detailed data & references for Quinidine Forms & strengths, pricing, billing codes, manufacturers, safety reports and sourcing — the data behind the page. Most people can stop here. Each section below opens on a tap.

Quinidine forms and strengths (how it comes)

Quinidine is available in 2 forms. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.

Need a version that does not list lactose, a gluten source, a dye or gelatin? Inactive ingredients differ by manufacturer: see Quinidine inactive ingredients by manufacturer.

Extended-release tablet

By mouth
Brands Quinidine Gluconate
How this form is used
What it may be used for
  • Quinidine Gluconate is used to restore normal rhythm in symptomatic atrial fibrillation/flutter.
  • Quinidine Gluconate is used to reduce relapses of atrial fibrillation/flutter in some high-risk patients.
  • Quinidine Gluconate is used for life-threatening recurrent ventricular arrhythmias.
Important instructions
  • Quinidine Gluconate extended-release tablets may be broken in half to adjust the dose.
  • Do not crush or chew Quinidine Gluconate tablets, as the extended-release effect is lost.
  • Quinidine Gluconate starts or dose changes are often done where heart monitoring is available.
Available strengths 1 strength
324 mg
4 FDA-listed product records ⓘ

Tablet

By mouth
How this form is used
What it may be used for
  • Quinidine Sulfate is used to restore normal rhythm in symptomatic atrial fibrillation/flutter.
  • Quinidine Sulfate is used to reduce relapses of atrial fibrillation/flutter in some high-risk patients.
  • Quinidine Sulfate is used for life-threatening recurrent ventricular arrhythmias.
  • Quinidine Sulfate is used as part of a regimen for life-threatening P. falciparum malaria.
Important instructions
  • Quinidine Sulfate tablets for malaria are part of a regimen built around Quinidine Gluconate Injection.
  • Quinidine Sulfate starts or dose changes are often done where heart monitoring is available.
Available strengths 2 strengths
200 mg 300 mg
4 FDA-listed product records ⓘ

Quinidine on the U.S. market: products, makers and brands

How Quinidine appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.

4 companies list 5 Quinidine product records with the FDA, mostly as extended-release tablet, tablet; the earliest marketing or approval year on record is 1950. Brand names on the directory include Cardioquin, Cin-Quin, Duraquin and 7 more; the rest are generics.

2
Dose forms ⓘ
4
Labelers (makers, repackagers, distributors)
2
Brand names
5
FDA-listed product records ⓘ
1950
Earliest FDA record ⓘ

FDA-listed product records by dose form (tablet variants merged) — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

Also listed with the FDA, not a patient dose form: Powder (4) — bulk drug substance sold to compounders/manufacturers and multi-item kits. These aren’t counted in the dose-form total above.

Epic Pharma, Llc40%
Eywa Pharma Inc20%
Golden State Medical Supply20%
Sun Pharmaceutical Industries, Inc.20%

Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

How widely Quinidine is used (Medicaid data)

A general measure of how commonly Quinidine is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.

Think of this as a proxy for how widely Quinidine is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.

185
Medicaid prescriptions filled (Q1–Q4 2025)
$98,977 gross Medicaid reimbursement (before mandatory rebates — net cost is lower)

How commonly is Quinidine prescribed? Of the 1,601 medications we measure, Quinidine ranks #1,457 by Medicaid prescriptions — more than 9% of them.

Where Quinidine ranks among the drugs we measure · Q1–Q4 2025 · neighbors ±5
Total prescriptions — #1,457 of 1,601
#1,452 Coal Tar 193 Rx #1,453 Ethacrynic Acid 192 Rx #1,454 Belinostat Injection 190 Rx #1,455 Danazol 190 Rx #1,456 Sirolimus (with albumi... 187 Rx #1,457 Quinidine 185 Rx #1,458 Tacrolimus Injection 184 Rx #1,459 Naxitamab-gqgk Injecti... 181 Rx #1,460 Nivolumab and relatlim... 177 Rx #1,461 Pexidartinib 175 Rx #1,462 RimabotulinumtoxinB In... 172 Rx

Utilization by Quinidine product

Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.

quinidine gluconate 324 MG Extended Release Oral Tablet

185 Medicaid prescriptions (Q1–Q4 2025) 100% of Quinidine prescriptions shown $98,977 gross reimbursement (before rebates) ≈ $535 per prescription (gross)

Summed across the 1 of 13 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 852920

Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.

Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Quinidine, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 1 of 13 listed Quinidine NDCs with Medicaid activity.

Compare Quinidine products

A representative set of FDA-listed product records for Quinidine — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)

Strength Route Manufacturer / Labeler Category ⓘ Details
💊Extended-release tablet
324 mg Oral Eywa Pharma Inc ANDA View NDC →
324 mg Oral Golden State Medical Supply ANDA View NDC →
324 mg Oral Sun Pharmaceutical Industries, Inc. ANDA View NDC →
💊Tablet
200 mg Oral Epic Pharma, Llc ANDA View NDC →
300 mg Oral Epic Pharma, Llc ANDA View NDC →

Showing 5 of 5 products — FDA National Drug Code Directory. See every product, package size and price: browse all 5 Quinidine NDCs →

Quinidine recall history

A recall is when a specific batch of a medicine is pulled from the market — usually a manufacturing issue, not a problem with the drug itself. Class I is most serious, Class III least.

The FDA’s enforcement reports list no Quinidine recalls since July 2021.

✅No Quinidine recalls on record since July 2021

Source: FDA enforcement (recall) reports, via openFDA; our copy was last updated Sep 24, 2026.

RxNorm Concept Web — From Ingredient to Every Form and Strength

This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.

Ingredient (IN) Quinidine RxCUI 9068 2 dose forms · 4 strengths
  1. Dose form (SCDF) Extended Release Oral Tablet RxCUI 373738 In current FDA listings
    Clinical drug / strength (SCD) gluconate 324 MG RxCUI 852920
  2. Dose form (SCDF) Oral Tablet RxCUI 373737 In current FDA listings
    Clinical drug / strength (SCD) polygalacturonate 275 MG RxCUI 852891 sulfate 200 MG RxCUI 852877 sulfate 300 MG RxCUI 852913

Look up RxCUI 9068 in the RxCUI Atlas →

RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.

💵 What Quinidine costs pharmacies (NADAC benchmark)

The national average invoice price pharmacies pay for the drug itself, from CMS's NADAC survey (data as of Aug 12, 2026). This is a supply-cost benchmark — not a retail price and not what you'd pay at the counter.

FormStrengthPharmacy acquisition benchmark
Tablet · Oral 200 mg $10.88 per tablet NDC details & price history
Why show this? Your out-of-pocket cost depends on insurance, pharmacy markup, and discounts — but the acquisition benchmark tells you whether the medication itself is inexpensive or costly, which strengths cost more per dose, and whether a cash-price quote is in a reasonable range. Each row links to the NDC-level record with its full price history.

Source: CMS National Average Drug Acquisition Cost (NADAC), a survey of retail pharmacy invoice prices. Benchmarks shown are the range across package sizes of a representative product for each form and strength — other manufacturers' products may differ.

Quinidine brand names

Quinidine is sold under 10 brand names in the FDA directory — Cardioquin, Cin-Quin, Duraquin, Quinact and others. A brand and its generic contain the same active ingredient; the brand name belongs to one company's product.

Cardioquin Cin-Quin Duraquin Quinact Quinaglute Quinalan Quinatime Quinidex Quinora Quinidine Gluconate

Who makes Quinidine: manufacturers and labelers

4 companies list Quinidine products with the FDA. By number of product records, the largest are Epic Pharma, Llc, Eywa Pharma Inc, Golden State Medical Supply. Labelers include manufacturers and repackagers; the product in your bottle depends on which one your pharmacy stocks.

Epic Pharma, Llc 2 Eywa Pharma Inc 1 Golden State Medical Supply 1 Sun Pharmaceutical Industries, Inc. 1

Sources for this Quinidine page

Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.

📄
FDA-filed drug labels (SPL) Uses, dosing, warnings & side effects from SPL records retrieved through openFDA; the linked representative set can be verified on DailyMed. ✓ Linked label effective Feb 1, 2018
🏭
Forms, brands & labelersAggregated from ingredient-matched FDA National Drug Code Directory product records for Quinidine.
📈
Real-world reportsThe FDA Adverse Event Reporting System (FAERS), served through openFDA.
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Recalls & shortagesopenFDA drug-enforcement reports and the FDA drug-shortage database.
🧾 Clinical label set — FDA-filed SPL labels retained for Quinidine after exact ingredient or ingredient-combination matching and applicable route/form matching
Clinical labels in scope
4
Finished products in the current FDA directory
5
Companies listing them (makers, repackagers, distributors)
4
FDA labeler codes behind them ⓘ
4
Linked representative label ⓘ
Sun Pharmaceutical Industries, Inc.
Linked label effective
Feb 1, 2018
Composite sections available
21
Linked SPL Set ID
5023f053-fcc4-4c2c-aa59-9ec198ad185e
Linked SPL Document ID
47cec250-341a-4694-a232-93106833a75e
Open the linked representative label on DailyMed ↗

How this page is built

HelloPharmacist combines public FDA and NLM records and does not author the underlying clinical facts. The plain-language sections are written with AI from the FDA-approved label text and reviewed by our pharmacy team before publication. Sun Pharmaceutical Industries, Inc. is the representative DailyMed label linked for verification and dates. This is general education, not medical advice: always talk to your doctor or pharmacist about your own medicines. How we build and review drug pages →