Methylsynephrine - Fluticasone Furoate, Umeclidinium, Vilanterol Interaction Details

Interaction Details

Fluticasone Furoate, Umeclidinium, Vilanterol is classified as belonging to the following category: Beta-Adrenergic Agonists

Methylsynephrine has beta agonist activity. Theoretically, concomitant use of large amounts of methylsynephrine might increase the cardiac inotropic effects of beta-agonists. Beta-adrenergic agonists include albuterol (Ventolin, Proventil), metaproterenol (Alupent), terbutaline (Brethine, Bricanyl), and isoproterenol (Isuprel).

Interaction Rating

Moderate

Likelihood of Occurrence

Possible

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists

References

Pawar RS, Grundel E. Overview of regulation of dietary supplements in the USA and issues of adulteration with phenethylamines (PEAs). Drug Test Anal 2017;9:500-517.
Cohen PA, Avula B, Venhuis B, Travis JC, Wang YH, Khan IA. Pharmaceutical doses of the banned stimulant oxilofrine found in dietary supplements sold in the USA. Drug Test Anal. 2017;9(1):135-142.

Fluticasone Furoate, Umeclidinium, Vilanterol Overview

The combination of fluticasone, umeclidinium, and vilanterol is used to control wheezing, shortness of breath, coughing, and chest tightness caused by chronic obstructive pulmonary (COPD; a group of diseases that affect the lungs and airways, that includes chronic bronchitis and emphysema). It is also used in adults to control wheezing, shortness of breath, coughing, and chest tightness caused by asthma. Fluticasone is in a class of medications called steroids. Umeclidinium is in a class of medication called anticholinergics. Vilanterol is in a class of medications called long-acting beta-agonists (LABAs). The combination of fluticasone, umeclidinium, and vilanterol works by relaxing and opening air passages in the lungs, making it easier to breathe.

See More Information Regarding Fluticasone, Umeclidinium, and Vilanterol Oral Inhalation

Methylsynephrine - More Interactions

Methylsynephrine interacts with 190 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.

Major	The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur.
Moderate	Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur.
Minor	Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction.
Unknown	No interactions have been reported or no interaction data is currently available.