Panax Notoginseng - Ruxolitinib Interaction
Herbal: Panax Notoginseng
Also Known As: Panax notoginseng, Field Seven, Noto-Gin, Notoginseng, Samch'il, Sanchitongtshu, San Qi, San Qui, Sanchi, Sanchi Ginseng, Sanqi, Sanqi Powder, Sanshichi, Three Seven, Tian Qi, Tian San Qi, Tienchi, Tienchi Ginseng
Drug: Ruxolitinib
Brand names:
Jakafi, Opzelura
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 26, 2024
Interaction Details
There were no interactions found between Ruxolitinib and Panax Notoginseng. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Panax Notoginseng Overview
Panax notoginseng, also known as sanqi or tienchi ginseng, is a herb that is native to China, Vietnam, and Thailand. It is a member of the Panax genus, which also includes other well-known herbs such as ginseng and red ginseng.
Panax notoginseng has been used in traditional Chinese medicine to treat a variety of conditions and is believed to have anti-inflammatory as well as blood-stopping properties, It is most often used to treat internal and external bleeding, including nosebleeds, menstrual cramps, and blood in the urine. It is also used to treat hypertension, angina, and heart disease.
Although most parts of Panax notoginseng plant can be used commercially, the root is most commonly used in dietary supplements.
Ruxolitinib Overview
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Ruxolitinib is used to treat myelofibrosis (a cancer of the bone marrow in which the bone marrow is replaced by scar tissue and causes decreased blood cell production). It is also used to treat polycythemia vera (PV; a slow growing cancer of the blood in which the bone marrow makes too many red blood cells) in people who were not able to be treated successfully with hydroxyurea. Ruxolitinib is also used to treat acute graft versus host disease (aGVHD; a complication of hematopoietic stem-cell transplant [HSCT; a procedure that replaces diseased bone marrow with healthy bone marrow] that usually develops within the first months after HSCT) in adults and children 12 years of age and older who were treated unsuccessfully with steroid medications. It is also used to treat chronic GVHD (cGVHD; a complication of HSCT that usually develops at least 3 months after HSCT) in adults and children 12 years of age and older who were treated unsuccessfully with 1 or 2 other treatments. Ruxolitinib is in a class of medications called kinase inhibitors. It works to treat myelofibrosis and PV by blocking the signals that cause cancer cells to multiply. This helps to stop the spread of cancer cells. It works to treat GVHD by blocking the signals of the cells that cause GVHD.
Panax Notoginseng - More Interactions
Panax Notoginseng interacts with 205 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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