Ruxolitinib

Generic name: Pronounced as (rux'' oh li' ti nib)
Brand names
  • Jakafi
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Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 12/15/2021

Ruxolitinib is used to treat myelofibrosis (a cancer of the bone marrow in which the bone marrow is replaced by scar tissue and causes decreased blood cell production). It is also used to treat polycythemia vera (PV; a slow growing cancer of the blood in which the bone marrow makes too many red blood cells) in people who were not able to be treated successfully with hydroxyurea. Ruxolitinib is also used to treat acute graft versus host disease (aGVHD; a complication of hematopoietic stem-cell transplant [HSCT; a procedure that replaces diseased bone marrow with healthy bone marrow] that usually develops within the first months after HSCT) in adults and children 12 years of age and older who were treated unsuccessfully with steroid medications. It is also used to treat chronic GVHD (cGVHD; a complication of HSCT that usually develops at least 3 months after HSCT) in adults and children 12 years of age and older who were treated unsuccessfully with 1 or 2 other treatments. Ruxolitinib is in a class of medications called kinase inhibitors. It works to treat myelofibrosis and PV by blocking the signals that cause cancer cells to multiply. This helps to stop the spread of cancer cells. It works to treat GVHD by blocking the signals of the cells that cause GVHD.

Ruxolitinib comes as a tablet to take by mouth. It is usually taken with or without food two times a day. Take ruxolitinib at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take ruxolitinib exactly as directed. Do not take more or less of it, or take it more often than prescribed by your doctor.

If you are being treated for myelofibrosis or PV your doctor may start you on a low dose of ruxolitinib for the first four weeks of treatment, and gradually increase your dose after that time, not more than once every 2 weeks. If you are being treated for acute GVHD your doctor may start you on a low dose of ruxolitinib and may increase your dose after at least 3 days of therapy. If you are being treated for acute or chronic GVHD your doctor may gradually lower your dose of ruxolitinib after at least 6 months of therapy.

Swallow the tablets whole; do not chew or crush them.

If you can not have food by mouth and have a nasogastric (NG) tube, your doctor may tell you to take ruxolitinib through the nasogastric (NG) tube. Your doctor or pharmacist will explain how to prepare ruxolitinib to give through an NG tube.

Your doctor will order blood tests before and during your treatment to see how you are affected by this medication. Your doctor may increase or decrease your dose of ruxolitinib during your treatment, or may tell you to stop taking ruxolitinib for awhile. This depends on how well the medication works for you, your lab test results, and if you experience side effects. Talk to your doctor about how you are feeling during your treatment. Continue to take ruxolitinib even if you feel well. Do not stop taking ruxolitinib without talking to your doctor. If your doctor decides to stop your treatment with ruxolitinib, your doctor may decrease your dose gradually.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking ruxolitinib,

  • tell your doctor and pharmacist if you are allergic to ruxolitinib, any other medications, or any of the ingredients in ruxolitinib. Ask your pharmacist for a list of the ingredients.

  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: antifungal medications including itraconazole (Sporanox), ketoconazole, and voriconazole (Vfend); carbamazepine (Carbatrol, Equetro, Tegretol, others); clarithromycin; efavirenz (Sustiva, in Atripla, Symfi); erythromycin (E.E.S, Eryc, Ery-tab); fluconazole (Diflucan); HIV protease inhibitors including indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, in Kaletra, Viekira Pak), and saquinavir (Invirase); nefazodone; nevirapine (Viramune); phenytoin (Dilantin, Phenytek); pioglitazone (Actos, in Oseni, Duetact); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, in Rifamate, Rifater); and telaprevir (Incivik). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with ruxolitinib, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

  • tell your doctor what herbal products you are taking, especially St. John's wort.

  • tell your doctor if you have anemia, an infection, if you are on dialysis, or if you were recently around someone who has tuberculosis (TB, a severe lung infection) or visited or lived where TB is common. Also tell your doctor if you are a current or past smoker; if you have or have ever had TB; high cholesterol or triglycerides; a blood clot, heart attack, stroke, or other heart problems; skin cancer; herpes zoster (shingles); hepatitis B or other liver disease; or kidney disease.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking ruxolitinib, call your doctor. You should not breast-feed while taking ruxolitinib and for 2 weeks after your final dose.

Unless your doctor tells you otherwise, continue your normal diet.

Skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Ruxolitinib may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • dizziness

    • headache

    • tiredness

    • shortness of breath

    • weight gain

    • gas

    • diarrhea

    • constipation

    • nausea

    • rash

    • muscle or joint pain

    • swelling of the arms, legs or other parts of the body

  • Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:

    • unusual or heavy bleeding or bruising

    • fever, sore throat, chills, cough, chest pain, night sweats, frequent, painful, urgent urination, and other signs of infection

    • burning, tingling, itching, or skin sensitivity on one side of the body or face with painful rash or blisters appearing several days later.

    • new sores, bumps, or discoloration or other changes to the skin

    • pale skin, tiredness, or shortness of breath (especially while exercising)

    • difficulty moving or keeping your balance, weakness of the legs or arms that keeps getting worse, difficulty understanding or speaking, loss of memory, vision problems, or changes in personality

    • swelling, pain, tenderness, warmth or redness in one or both legs

    • shortness of breath

    • difficulty breathing

    • pain in the chest, arms, back, neck, jaw, or stomach

    • breaking out in cold sweat

    • nausea or vomiting

    • lightheadedness

    • slow or difficult speech

    • numbness or weakness of the face, arm, or leg on one side of your body

  • Ruxolitinib may increase the risk that you will develop skin cancer or other cancers. Talk to your doctor about the risks of taking this medication.

  • Ruxolitinib may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include the following:

  • unusual bleeding or bruising

  • dizziness

  • headache

  • tiredness

  • fever, sore throat, chills, cough, and other signs of infection

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to ruxolitinib.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Leflunomide Leflunomide The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Leflunomide.
Delavirdine Delavirdine The metabolism of Ruxolitinib can be decreased when combined with Delavirdine.
Anagrelide Anagrelide The risk or severity of bleeding can be increased when Anagrelide is combined with Ruxolitinib.
Cilostazol Cilostazol Cilostazol may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Clopidogrel Clopidogrel The risk or severity of bleeding can be increased when Clopidogrel is combined with Ruxolitinib.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The metabolism of Ruxolitinib can be decreased when combined with Erythromycin.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) Conjugated estrogens may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Fenofibrate Fenofibrate The metabolism of Ruxolitinib can be decreased when combined with Fenofibrate.
Guanfacine Guanfacine Ruxolitinib may increase the bradycardic activities of Guanfacine.
Magnesium Hydroxide Magnesium Hydroxide Ruxolitinib may decrease the excretion rate of Magnesium hydroxide which could result in a higher serum level.
Methylergonovine Methylergonovine The metabolism of Ruxolitinib can be decreased when combined with Methylergometrine.
Mycophenolate Mycophenolate The risk or severity of adverse effects can be increased when Mycophenolic acid is combined with Ruxolitinib.
Olsalazine Olsalazine Olsalazine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Penbutolol Penbutolol Ruxolitinib may increase the bradycardic activities of Acebutolol.
Potassium Potassium Potassium cation may increase the excretion rate of Ruxolitinib which could result in a lower serum level and potentially a reduction in efficacy.
Prednisone Prednisone The risk or severity of adverse effects can be increased when Prednisone is combined with Ruxolitinib.
Ranitidine Ranitidine Ranitidine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Reserpine Reserpine Reserpine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Rizatriptan Rizatriptan Rizatriptan may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Sumatriptan Sumatriptan Sumatriptan may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Tacrolimus Tacrolimus Tacrolimus may increase the immunosuppressive activities of Ruxolitinib.
Tizanidine Tizanidine Ruxolitinib may increase the bradycardic activities of Tizanidine.
Triamcinolone Triamcinolone The metabolism of Ruxolitinib can be increased when combined with Triamcinolone.
Ampicillin Injection Ampicillin Injection Ampicillin may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Doxycycline Injection Doxycycline Injection The metabolism of Ruxolitinib can be decreased when combined with Doxycycline.
Fluconazole Injection Fluconazole Injection The serum concentration of Ruxolitinib can be increased when it is combined with Fluconazole.
Foscarnet Injection Foscarnet Injection Foscarnet may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Hydromorphone Injection Hydromorphone Injection Hydromorphone may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Interferon Beta-1b Injection Interferon Beta-1b Injection The risk or severity of adverse effects can be increased when Interferon beta-1b is combined with Ruxolitinib.
Interferon Gamma-1b Injection Interferon Gamma-1b Injection The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Ruxolitinib.
Levofloxacin Injection Levofloxacin Injection Levofloxacin may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Meperidine Injection Meperidine Injection The metabolism of Ruxolitinib can be increased when combined with Meperidine.
Methylprednisolone Injection Methylprednisolone Injection The metabolism of Ruxolitinib can be increased when combined with Methylprednisolone.
Metoclopramide Injection Metoclopramide Injection Metoclopramide may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Metronidazole Injection Metronidazole Injection The metabolism of Ruxolitinib can be decreased when combined with Metronidazole.
Pamidronate Injection Pamidronate Injection Pamidronic acid may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Vancomycin Injection Vancomycin Injection Ruxolitinib may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Zidovudine Injection Zidovudine Injection The risk or severity of adverse effects can be increased when Zidovudine is combined with Ruxolitinib.
Altretamine Altretamine Amphetamine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Cefuroxime Cefuroxime Cefuroxime may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Cyclosporine Cyclosporine Ruxolitinib may increase the immunosuppressive activities of Cyclosporine.
Enoxaparin Injection Enoxaparin Injection The risk or severity of bleeding can be increased when Enoxaparin is combined with Ruxolitinib.
Torsemide Torsemide Torasemide may increase the excretion rate of Ruxolitinib which could result in a lower serum level and potentially a reduction in efficacy.
Hydroxychloroquine Hydroxychloroquine The risk or severity of adverse effects can be increased when Hydroxychloroquine is combined with Ruxolitinib.
Meloxicam Meloxicam Meloxicam may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Orlistat Orlistat The metabolism of Ruxolitinib can be increased when combined with Orlistat.
Oxcarbazepine Oxcarbazepine The metabolism of Ruxolitinib can be increased when combined with Oxcarbazepine.
Pantoprazole Pantoprazole Pantoprazole may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Temozolomide Temozolomide The risk or severity of adverse effects can be increased when Temozolomide is combined with Ruxolitinib.
Zaleplon Zaleplon Zaleplon may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Anakinra Anakinra The metabolism of Ruxolitinib can be increased when combined with Anakinra.
Linezolid Linezolid The risk or severity of adverse effects can be increased when Linezolid is combined with Ruxolitinib.
Pentosan Polysulfate Pentosan Polysulfate The risk or severity of bleeding can be increased when Pentosan polysulfate is combined with Ruxolitinib.
Rivastigmine Rivastigmine Ruxolitinib may increase the bradycardic activities of Rivastigmine.
Etanercept Injection Etanercept Injection The metabolism of Ruxolitinib can be increased when combined with Etanercept.
Modafinil Modafinil The metabolism of Ruxolitinib can be increased when combined with Modafinil.
Perindopril Perindopril Perindopril may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Tenofovir Tenofovir The metabolism of Ruxolitinib can be decreased when combined with Tenofovir.
Choline Magnesium Trisalicylate Choline Magnesium Trisalicylate Choline magnesium trisalicylate may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Sirolimus Sirolimus The risk or severity of adverse effects can be increased when Sirolimus is combined with Ruxolitinib.
Epinephrine Injection Epinephrine Injection The metabolism of Ruxolitinib can be decreased when combined with Epinephrine.
Epirubicin Epirubicin The risk or severity of adverse effects can be increased when Epirubicin is combined with Ruxolitinib.
Eplerenone Eplerenone Eplerenone may increase the excretion rate of Ruxolitinib which could result in a lower serum level and potentially a reduction in efficacy.
Zonisamide Zonisamide Ruxolitinib may increase the bradycardic activities of Zonisamide.
Adalimumab Injection Adalimumab Injection The metabolism of Ruxolitinib can be increased when combined with Adalimumab.
Atomoxetine Atomoxetine Atomoxetine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Glatiramer Injection Glatiramer Injection The risk or severity of adverse effects can be increased when Glatiramer is combined with Ruxolitinib.
Teriparatide Injection Teriparatide Injection The therapeutic efficacy of Teriparatide can be decreased when used in combination with Ruxolitinib.
Atazanavir Atazanavir The metabolism of Ruxolitinib can be decreased when combined with Atazanavir.
Almotriptan Almotriptan Almotriptan may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Mefloquine Mefloquine The metabolism of Ruxolitinib can be decreased when combined with Mefloquine.
Rosuvastatin Rosuvastatin The metabolism of Ruxolitinib can be decreased when combined with Rosuvastatin.
Aprepitant Aprepitant The metabolism of Ruxolitinib can be decreased when combined with Aprepitant.
Emtricitabine Emtricitabine Emtricitabine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Memantine Memantine Memantine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Tadalafil Tadalafil Tadalafil may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Progesterone Progesterone The metabolism of Ruxolitinib can be increased when combined with Progesterone.
Darbepoetin Alfa Injection Darbepoetin Alfa Injection The risk or severity of Thrombosis can be increased when Darbepoetin alfa is combined with Ruxolitinib.
Infliximab Injection Infliximab Injection The metabolism of Ruxolitinib can be increased when combined with Infliximab.
Rifaximin Rifaximin The metabolism of Ruxolitinib can be increased when combined with Rifaximin.
Duloxetine Duloxetine The metabolism of Ruxolitinib can be decreased when combined with Duloxetine.
Norethindrone Norethindrone The metabolism of Ruxolitinib can be decreased when combined with Norethisterone.
Tinidazole Tinidazole Tinidazole may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Bosentan Bosentan The metabolism of Ruxolitinib can be increased when combined with Bosentan.
Cefditoren Cefditoren Cefdinir may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Natalizumab Injection Natalizumab Injection The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Natalizumab.
Cyanocobalamin Injection Cyanocobalamin Injection Hydroxocobalamin may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Erlotinib Erlotinib The metabolism of Ruxolitinib can be decreased when combined with Erlotinib.
Eszopiclone Eszopiclone Eszopiclone may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Ganciclovir Ganciclovir Ganciclovir may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Palifermin Palifermin The therapeutic efficacy of Palifermin can be decreased when used in combination with Ruxolitinib.
Ribavirin Ribavirin Ribavirin may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Valganciclovir Valganciclovir Valganciclovir may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Voriconazole Voriconazole The metabolism of Ruxolitinib can be decreased when combined with Voriconazole.
Adefovir Adefovir Adefovir may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Dextroamphetamine Dextroamphetamine Amphetamine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Peginterferon Alfa-2a Injection Peginterferon Alfa-2a Injection The risk or severity of adverse effects can be increased when Peginterferon alfa-2a is combined with Ruxolitinib.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The risk or severity of adverse effects can be increased when Peginterferon alfa-2b is combined with Ruxolitinib.
Ramelteon Ramelteon Ramelteon may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Fentanyl Fentanyl Ruxolitinib may increase the bradycardic activities of Fentanyl.
Pregabalin Pregabalin Ruxolitinib may increase the bradycardic activities of Pregabalin.
Deferasirox Deferasirox The metabolism of Ruxolitinib can be increased when combined with Deferasirox.
Tipranavir Tipranavir The metabolism of Tipranavir can be decreased when combined with Ruxolitinib.
Felbamate Felbamate The metabolism of Ruxolitinib can be increased when combined with Felbamate.
Ranolazine Ranolazine The metabolism of Ruxolitinib can be decreased when combined with Ranolazine.
Abatacept Injection Abatacept Injection The metabolism of Ruxolitinib can be increased when combined with Abatacept.
Rasagiline Rasagiline Rasagiline may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Imatinib Imatinib The metabolism of Ruxolitinib can be decreased when combined with Imatinib.
Sitagliptin Sitagliptin Sitagliptin may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Varenicline Varenicline Varenicline may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Bevacizumab Injection Bevacizumab Injection The risk or severity of adverse effects can be increased when Bevacizumab is combined with Ruxolitinib.
Gefitinib Gefitinib The metabolism of Ruxolitinib can be decreased when combined with Gefitinib.
Albuterol Albuterol Salbutamol may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Paliperidone Paliperidone Paliperidone may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Bortezomib Bortezomib The risk or severity of adverse effects can be increased when Bortezomib is combined with Ruxolitinib.
Clofarabine Injection Clofarabine Injection The risk or severity of adverse effects can be increased when Clofarabine is combined with Ruxolitinib.
Hepatitis B Vaccine Hepatitis B Vaccine The therapeutic efficacy of Hepatitis B Vaccine (Recombinant) can be decreased when used in combination with Ruxolitinib.
Influenza Vaccine, Inactivated or Recombinant Influenza Vaccine, Inactivated or Recombinant The therapeutic efficacy of Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) can be decreased when used in combination with Ruxolitinib.
Influenza Vaccine, Live Intranasal Influenza Vaccine, Live Intranasal The risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Ruxolitinib.
Live Shingles (Zoster) Vaccine (ZVL) Live Shingles (Zoster) Vaccine (ZVL) The risk or severity of infection can be increased when Varicella Zoster Vaccine (Live/attenuated) is combined with Ruxolitinib.
Lubiprostone Lubiprostone Lubiprostone may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Oxaliplatin Injection Oxaliplatin Injection The risk or severity of adverse effects can be increased when Oxaliplatin is combined with Ruxolitinib.
Posaconazole Posaconazole The metabolism of Ruxolitinib can be decreased when combined with Posaconazole.
Primaquine Primaquine The metabolism of Ruxolitinib can be decreased when combined with Primaquine.
Rituximab Injection Rituximab Injection The risk or severity of adverse effects can be increased when Rituximab is combined with Ruxolitinib.
Darunavir Darunavir The serum concentration of Darunavir can be increased when it is combined with Ruxolitinib.
Pemetrexed Injection Pemetrexed Injection The risk or severity of adverse effects can be increased when Pemetrexed is combined with Ruxolitinib.
Vorinostat Vorinostat The risk or severity of adverse effects can be increased when Vorinostat is combined with Ruxolitinib.
Sorafenib Sorafenib The metabolism of Ruxolitinib can be decreased when combined with Sorafenib.
Sunitinib Sunitinib The metabolism of Ruxolitinib can be decreased when combined with Sunitinib.
Lapatinib Lapatinib The metabolism of Ruxolitinib can be decreased when combined with Lapatinib.
Levocetirizine Levocetirizine Levocetirizine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Pegaptanib Injection Pegaptanib Injection Pegaptanib may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Dasatinib Dasatinib The metabolism of Ruxolitinib can be decreased when combined with Dasatinib.
Armodafinil Armodafinil The metabolism of Ruxolitinib can be increased when combined with Armodafinil.
Azacitidine Injection Azacitidine Injection The risk or severity of adverse effects can be increased when Azacitidine is combined with Ruxolitinib.
Ivermectin Ivermectin The metabolism of Ruxolitinib can be increased when combined with Ivermectin.
Temsirolimus Temsirolimus The risk or severity of adverse effects can be increased when Temsirolimus is combined with Ruxolitinib.
Nelarabine Injection Nelarabine Injection The risk or severity of adverse effects can be increased when Nelarabine is combined with Ruxolitinib.
Lenalidomide Lenalidomide The risk or severity of adverse effects can be increased when Lenalidomide is combined with Ruxolitinib.
Nilotinib Nilotinib The metabolism of Ruxolitinib can be decreased when combined with Nilotinib.
Bexarotene Bexarotene The metabolism of Ruxolitinib can be increased when combined with Bexarotene.
Budesonide Budesonide The metabolism of Ruxolitinib can be increased when combined with Budesonide.
Chloramphenicol Injection Chloramphenicol Injection The metabolism of Ruxolitinib can be decreased when combined with Chloramphenicol.
Decitabine Injection Decitabine Injection The risk or severity of adverse effects can be increased when Decitabine is combined with Ruxolitinib.
Desmopressin Desmopressin Desmopressin may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Doripenem Injection Doripenem Injection Doripenem may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Etravirine Etravirine The metabolism of Ruxolitinib can be increased when combined with Etravirine.
Arsenic Trioxide Injection Arsenic Trioxide Injection The risk or severity of adverse effects can be increased when Arsenic trioxide is combined with Ruxolitinib.
Mitoxantrone Injection Mitoxantrone Injection The metabolism of Ruxolitinib can be decreased when combined with Mitoxantrone.
Desvenlafaxine Desvenlafaxine The metabolism of Ruxolitinib can be decreased when combined with Desvenlafaxine.
Cevimeline Cevimeline Cevimeline may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Nebivolol Nebivolol Ruxolitinib may increase the bradycardic activities of Nebivolol.
Tretinoin Tretinoin The risk or severity of adverse effects can be increased when Tretinoin is combined with Ruxolitinib.
Bendamustine Injection Bendamustine Injection The risk or severity of adverse effects can be increased when Bendamustine is combined with Ruxolitinib.
Pilocarpine Pilocarpine The metabolism of Ruxolitinib can be decreased when combined with Pilocarpine.
Certolizumab Injection Certolizumab Injection The metabolism of Certolizumab pegol can be increased when combined with Ruxolitinib.
Ixabepilone Injection Ixabepilone Injection The risk or severity of adverse effects can be increased when Ixabepilone is combined with Ruxolitinib.
Irinotecan Injection Irinotecan Injection The risk or severity of adverse effects can be increased when Irinotecan is combined with Ruxolitinib.
Daptomycin Injection Daptomycin Injection Daptomycin may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Estramustine Estramustine The risk or severity of adverse effects can be increased when Estramustine is combined with Ruxolitinib.
Mitotane Mitotane The metabolism of Ruxolitinib can be increased when combined with Mitotane.
Methylnaltrexone Injection Methylnaltrexone Injection Methylnaltrexone may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Alemtuzumab Injection (Chronic Lymphocytic Leukemia) Alemtuzumab Injection (Chronic Lymphocytic Leukemia) The risk or severity of adverse effects can be increased when Alemtuzumab is combined with Ruxolitinib.
Rufinamide Rufinamide The metabolism of Ruxolitinib can be increased when combined with Rufinamide.
Midazolam Midazolam The metabolism of Ruxolitinib can be decreased when combined with Midazolam.
Dexrazoxane Injection Dexrazoxane Injection The risk or severity of adverse effects can be increased when Dexrazoxane is combined with Ruxolitinib.
Ibritumomab Injection Ibritumomab Injection The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with Ruxolitinib.
Milnacipran Milnacipran The metabolism of Ruxolitinib can be decreased when combined with Milnacipran.
Plerixafor Injection Plerixafor Injection Plerixafor may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Fesoterodine Fesoterodine Fesoterodine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Betaxolol Betaxolol Ruxolitinib may increase the bradycardic activities of Betaxolol.
Prasugrel Prasugrel Prasugrel may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Lacosamide Lacosamide Ruxolitinib may increase the bradycardic activities of Lacosamide.
Everolimus Everolimus The risk or severity of adverse effects can be increased when Everolimus is combined with Ruxolitinib.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) Tolvaptan may increase the excretion rate of Ruxolitinib which could result in a lower serum level and potentially a reduction in efficacy.
Dronedarone Dronedarone The serum concentration of Dronedarone can be increased when it is combined with Ruxolitinib.
Pralatrexate Injection Pralatrexate Injection The risk or severity of adverse effects can be increased when Pralatrexate is combined with Ruxolitinib.
Palonosetron Injection Palonosetron Injection Palonosetron may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Saxagliptin Saxagliptin Saxagliptin may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Telavancin Injection Telavancin Injection Telavancin may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Topotecan Topotecan The metabolism of Ruxolitinib can be increased when combined with Topotecan.
Golimumab Injection Golimumab Injection The metabolism of Ruxolitinib can be increased when combined with Golimumab.
Pazopanib Pazopanib The metabolism of Ruxolitinib can be decreased when combined with Pazopanib.
Albendazole Albendazole The metabolism of Ruxolitinib can be decreased when combined with Albendazole.
Denosumab Injection Denosumab Injection The risk or severity of adverse effects can be increased when Denosumab is combined with Ruxolitinib.
Dabigatran Dabigatran The risk or severity of bleeding can be increased when Dabigatran is combined with Ruxolitinib.
Tocilizumab Injection Tocilizumab Injection The metabolism of Ruxolitinib can be increased when combined with Tocilizumab.
Dalfampridine Dalfampridine Dalfampridine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Fingolimod Fingolimod Ruxolitinib may increase the bradycardic activities of Fingolimod.
Eribulin Injection Eribulin Injection The risk or severity of adverse effects can be increased when Eribulin is combined with Ruxolitinib.
Cabazitaxel Injection Cabazitaxel Injection The risk or severity of adverse effects can be increased when Cabazitaxel is combined with Ruxolitinib.
Ceftaroline Injection Ceftaroline Injection Ceftaroline fosamil may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Acetaminophen Injection Acetaminophen Injection The metabolism of Acetaminophen can be increased when combined with Ruxolitinib.
Ipilimumab Injection Ipilimumab Injection Ipilimumab may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Denileukin Diftitox Injection Denileukin Diftitox Injection The metabolism of Ruxolitinib can be decreased when combined with Aldesleukin.
Sipuleucel-T Injection Sipuleucel-T Injection The therapeutic efficacy of Sipuleucel-T can be decreased when used in combination with Ruxolitinib.
Terbutaline Injection Terbutaline Injection Terbutaline may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Belimumab Injection Belimumab Injection The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Belimumab.
Busulfan Injection Busulfan Injection The risk or severity of adverse effects can be increased when Busulfan is combined with Ruxolitinib.
Roflumilast Roflumilast Roflumilast may increase the immunosuppressive activities of Ruxolitinib.
Linagliptin Linagliptin The metabolism of Ruxolitinib can be decreased when combined with Linagliptin.
Rilpivirine Rilpivirine The metabolism of Ruxolitinib can be decreased when combined with Rilpivirine.
Telaprevir Telaprevir The metabolism of Ruxolitinib can be decreased when combined with Glecaprevir.
Potassium Iodide Potassium Iodide The therapeutic efficacy of Potassium Iodide can be decreased when used in combination with Ruxolitinib.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Ruxolitinib can be increased when combined with Cyclophosphamide.
Rivaroxaban Rivaroxaban Rivaroxaban may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Ticagrelor Ticagrelor The metabolism of Ruxolitinib can be decreased when combined with Ticagrelor.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The metabolism of Ruxolitinib can be decreased when combined with Brentuximab vedotin.
Clobazam Clobazam The metabolism of Ruxolitinib can be increased when combined with Clobazam.
Vemurafenib Vemurafenib The metabolism of Ruxolitinib can be increased when combined with Vemurafenib.
Belatacept Injection Belatacept Injection The risk or severity of adverse effects can be increased when Belatacept is combined with Ruxolitinib.
Ivacaftor Ivacaftor The metabolism of Ruxolitinib can be decreased when combined with Ivacaftor.
Basiliximab Injection Basiliximab Injection The risk or severity of adverse effects can be increased when Basiliximab is combined with Ruxolitinib.
Deferiprone Deferiprone Deferiprone may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Crizotinib Crizotinib The metabolism of Crizotinib can be decreased when combined with Ruxolitinib.
Melphalan Injection Melphalan Injection The risk or severity of adverse effects can be increased when Melphalan is combined with Ruxolitinib.
Cabergoline Cabergoline The metabolism of Ruxolitinib can be decreased when combined with Cabergoline.
Naloxone Injection Naloxone Injection The metabolism of Ruxolitinib can be decreased when combined with Naloxone.
Eculizumab Injection Eculizumab Injection The risk or severity of adverse effects can be increased when Eculizumab is combined with Ruxolitinib.
Fondaparinux Injection Fondaparinux Injection Fondaparinux may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Carfilzomib Injection Carfilzomib Injection The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Carfilzomib.
Iloprost Iloprost The risk or severity of bleeding can be increased when Iloprost is combined with Ruxolitinib.
Enzalutamide Enzalutamide The metabolism of Enzalutamide can be increased when combined with Ruxolitinib.
Mirabegron Mirabegron Ruxolitinib may decrease the excretion rate of Mirabegron which could result in a higher serum level.
Regorafenib Regorafenib Ruxolitinib may increase the bradycardic activities of Regorafenib.
Bosutinib Bosutinib The metabolism of Ruxolitinib can be decreased when combined with Bosutinib.
Corticotropin, Repository Injection Corticotropin, Repository Injection The metabolism of Ruxolitinib can be increased when combined with Corticotropin.
Teriflunomide Teriflunomide The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Teriflunomide.
Teduglutide Injection Teduglutide Injection Ruxolitinib may decrease the excretion rate of Teduglutide which could result in a higher serum level.
Icosapent Ethyl Icosapent Ethyl The risk or severity of bleeding can be increased when Icosapent ethyl is combined with Ruxolitinib.
Tofacitinib Tofacitinib Ruxolitinib may increase the immunosuppressive activities of Tofacitinib.
Alogliptin Alogliptin Alogliptin may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Dimethyl Fumarate Dimethyl Fumarate The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Dimethyl fumarate.
Ponatinib Ponatinib The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Ponatinib.
Pomalidomide Pomalidomide The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Pomalidomide.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The metabolism of Ruxolitinib can be decreased when combined with Trastuzumab emtansine.
Apixaban Apixaban The risk or severity of bleeding can be increased when Apixaban is combined with Ruxolitinib.
Canagliflozin Canagliflozin Ruxolitinib may increase the excretion rate of Canagliflozin which could result in a lower serum level and potentially a reduction in efficacy.
Methazolamide Methazolamide Methazolamide may increase the excretion rate of Ruxolitinib which could result in a lower serum level and potentially a reduction in efficacy.
Dabrafenib Dabrafenib The metabolism of Ruxolitinib can be increased when combined with Dabrafenib.
Trametinib Trametinib The metabolism of Trametinib can be increased when combined with Ruxolitinib.
Levomilnacipran Levomilnacipran Ruxolitinib may decrease the excretion rate of Levomilnacipran which could result in a higher serum level.
Ertapenem Injection Ertapenem Injection Ertapenem may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Vortioxetine Vortioxetine Ruxolitinib may decrease the excretion rate of Vortioxetine which could result in a higher serum level.
Perampanel Perampanel The metabolism of Ruxolitinib can be increased when combined with Perampanel.
Ibrutinib Ibrutinib The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Ibrutinib.
Lomitapide Lomitapide The metabolism of Ruxolitinib can be decreased when combined with Lomitapide.
Ketorolac Injection Ketorolac Injection Ketorolac may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Obinutuzumab Injection Obinutuzumab Injection The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Obinutuzumab.
Simeprevir Simeprevir The metabolism of Ruxolitinib can be decreased when combined with Simeprevir.
Sofosbuvir Sofosbuvir Ruxolitinib may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Dapagliflozin Dapagliflozin Dapagliflozin may increase the excretion rate of Ruxolitinib which could result in a lower serum level and potentially a reduction in efficacy.
Apremilast Apremilast The metabolism of Ruxolitinib can be increased when combined with Apremilast.
Droxidopa Droxidopa Droxidopa may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Ceritinib Ceritinib Ruxolitinib may increase the bradycardic activities of Ceritinib.
Siltuximab Injection Siltuximab Injection The metabolism of Siltuximab can be increased when combined with Ruxolitinib.
Eslicarbazepine Eslicarbazepine The metabolism of Ruxolitinib can be increased when combined with Eslicarbazepine.
Vedolizumab Injection Vedolizumab Injection The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Vedolizumab.
Belinostat Injection Belinostat Injection The risk or severity of adverse effects can be increased when Belinostat is combined with Ruxolitinib.
Idelalisib Idelalisib The risk or severity of adverse effects can be increased when Idelalisib is combined with Ruxolitinib.
Testosterone Injection Testosterone Injection The metabolism of Ruxolitinib can be increased when combined with Testosterone.
Oritavancin Injection Oritavancin Injection The metabolism of Ruxolitinib can be increased when combined with Oritavancin.
Vorapaxar Vorapaxar The metabolism of Ruxolitinib can be decreased when combined with Vorapaxar.
Suvorexant Suvorexant The metabolism of Ruxolitinib can be decreased when combined with Suvorexant.
Edoxaban Edoxaban Ruxolitinib may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Peginterferon Beta-1a Injection Peginterferon Beta-1a Injection The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Peginterferon beta-1a.
Olaparib Olaparib The metabolism of Olaparib can be decreased when combined with Ruxolitinib.
Blinatumomab Injection Blinatumomab Injection The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Blinatumomab.
Methamphetamine Methamphetamine Metamfetamine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Tasimelteon Tasimelteon The metabolism of Tasimelteon can be decreased when combined with Ruxolitinib.
Lanreotide Injection Lanreotide Injection Ruxolitinib may increase the bradycardic activities of Lanreotide.
Pirfenidone Pirfenidone The risk or severity of adverse effects can be increased when Pirfenidone is combined with Ruxolitinib.
Nintedanib Nintedanib The metabolism of Ruxolitinib can be decreased when combined with Nintedanib.
Secukinumab Injection Secukinumab Injection The metabolism of Secukinumab can be increased when combined with Ruxolitinib.
Palbociclib Palbociclib The metabolism of Palbociclib can be decreased when combined with Ruxolitinib.
Lenvatinib Lenvatinib The metabolism of Ruxolitinib can be increased when combined with Lenvatinib.
Panobinostat Panobinostat The risk or severity of adverse effects can be increased when Panobinostat is combined with Ruxolitinib.
Dinutuximab Injection Dinutuximab Injection The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Dinutuximab.
Haloperidol Injection Haloperidol Injection The serum concentration of Ruxolitinib can be increased when it is combined with Haloperidol.
Ivabradine Ivabradine Ruxolitinib may increase the bradycardic activities of Ivabradine.
Amiloride Amiloride Amiloride may increase the excretion rate of Ruxolitinib which could result in a lower serum level and potentially a reduction in efficacy.
Isavuconazonium Injection Isavuconazonium Injection The metabolism of Ruxolitinib can be increased when combined with Isavuconazonium.
Macitentan Macitentan Ruxolitinib may decrease the excretion rate of Macitentan which could result in a higher serum level.
Prednisolone Prednisolone The metabolism of Ruxolitinib can be increased when combined with Prednisolone.
Ziprasidone Injection Ziprasidone Injection The metabolism of Ruxolitinib can be decreased when combined with Ziprasidone.
Penicillin G Procaine Injection Penicillin G Procaine Injection Ruxolitinib may decrease the excretion rate of Procaine benzylpenicillin which could result in a higher serum level.
Cobimetinib Cobimetinib The metabolism of Ruxolitinib can be decreased when combined with Cobimetinib.
Mepolizumab Injection Mepolizumab Injection The risk or severity of adverse effects can be increased when Mepolizumab is combined with Ruxolitinib.
Trabectedin Injection Trabectedin Injection The risk or severity of adverse effects can be increased when Trabectedin is combined with Ruxolitinib.
Osimertinib Osimertinib The metabolism of Ruxolitinib can be increased when combined with Osimertinib.
Ixazomib Ixazomib Ruxolitinib may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Rifapentine Rifapentine The metabolism of Ruxolitinib can be increased when combined with Rifapentine.
Lesinurad Lesinurad The metabolism of Lesinurad can be increased when combined with Ruxolitinib.
Amphotericin B Liposomal Injection Amphotericin B Liposomal Injection The metabolism of Ruxolitinib can be decreased when combined with Amphotericin B.
Dexamethasone Injection Dexamethasone Injection The metabolism of Ruxolitinib can be increased when combined with Dexamethasone.
Defibrotide Injection Defibrotide Injection The risk or severity of bleeding can be increased when Defibrotide is combined with Ruxolitinib.
Ixekizumab Injection Ixekizumab Injection The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Ixekizumab.
Brivaracetam Injection Brivaracetam Injection Brivaracetam may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Venetoclax Venetoclax The metabolism of Ruxolitinib can be decreased when combined with Venetoclax.
Cobicistat Cobicistat The metabolism of Ruxolitinib can be decreased when combined with Cobicistat.
Midodrine Midodrine Ruxolitinib may increase the bradycardic activities of Midodrine.
Furosemide Injection Furosemide Injection Furosemide may increase the excretion rate of Ruxolitinib which could result in a lower serum level and potentially a reduction in efficacy.
Rucaparib Rucaparib The metabolism of Ruxolitinib can be decreased when combined with Rucaparib.
Lixisenatide Injection Lixisenatide Injection Ruxolitinib may decrease the excretion rate of Lixisenatide which could result in a higher serum level.
Ribociclib Ribociclib The metabolism of Ruxolitinib can be decreased when combined with Ribociclib.
Brodalumab Injection Brodalumab Injection The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Brodalumab.
Parathyroid Hormone Injection Parathyroid Hormone Injection The therapeutic efficacy of Parathyroid hormone can be decreased when used in combination with Ruxolitinib.
Brigatinib Brigatinib The metabolism of Ruxolitinib can be increased when combined with Brigatinib.
Doxepin (Insomnia) Doxepin (Insomnia) Doxepin may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Deutetrabenazine Deutetrabenazine Ruxolitinib may decrease the excretion rate of Deutetrabenazine which could result in a higher serum level.
Valbenazine Valbenazine Ruxolitinib may decrease the excretion rate of Valbenazine which could result in a higher serum level.
Deflazacort Deflazacort The metabolism of Deflazacort can be increased when combined with Ruxolitinib.
Ocrelizumab Injection Ocrelizumab Injection The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Ocrelizumab.
Naldemedine Naldemedine Ruxolitinib may decrease the excretion rate of Naldemedine which could result in a higher serum level.
Sarilumab Injection Sarilumab Injection The metabolism of Sarilumab can be increased when combined with Ruxolitinib.
Midostaurin Midostaurin The metabolism of Ruxolitinib can be decreased when combined with Midostaurin.
Guselkumab Injection Guselkumab Injection The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Guselkumab.
Abaloparatide Injection Abaloparatide Injection The therapeutic efficacy of Abaloparatide can be decreased when used in combination with Ruxolitinib.
Enasidenib Enasidenib The metabolism of Ruxolitinib can be increased when combined with Enasidenib.
Aprepitant/Fosaprepitant Injection Aprepitant/Fosaprepitant Injection The metabolism of Ruxolitinib can be increased when combined with Fosaprepitant.
Benznidazole Benznidazole Ruxolitinib may decrease the excretion rate of Benznidazole which could result in a higher serum level.
Delafloxacin Delafloxacin Ruxolitinib may decrease the excretion rate of Delafloxacin which could result in a higher serum level.
Betrixaban Betrixaban The risk or severity of bleeding can be increased when Betrixaban is combined with Ruxolitinib.
Acalabrutinib Acalabrutinib The metabolism of Ruxolitinib can be decreased when combined with Acalabrutinib.
Gemtuzumab Ozogamicin Injection Gemtuzumab Ozogamicin Injection The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Ruxolitinib.
Letermovir Letermovir The metabolism of Ruxolitinib can be decreased when combined with Letermovir.
Ertugliflozin Ertugliflozin Ertugliflozin may increase the excretion rate of Ruxolitinib which could result in a lower serum level and potentially a reduction in efficacy.
Buprenorphine Injection Buprenorphine Injection The metabolism of Ruxolitinib can be decreased when combined with Buprenorphine.
Apalutamide Apalutamide The metabolism of Apalutamide can be increased when combined with Ruxolitinib.
Penicillamine Penicillamine The risk or severity of adverse effects can be increased when Penicillamine is combined with Ruxolitinib.
Fostamatinib Fostamatinib The metabolism of Ruxolitinib can be decreased when combined with Fostamatinib.
Baricitinib Baricitinib The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Baricitinib.
Lofexidine Lofexidine Lofexidine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Plazomicin Injection Plazomicin Injection Ruxolitinib may decrease the excretion rate of Plazomicin which could result in a higher serum level.
Ivosidenib Ivosidenib The metabolism of Ruxolitinib can be increased when combined with Ivosidenib.
Dacomitinib Dacomitinib The metabolism of Ruxolitinib can be decreased when combined with Dacomitinib.
Duvelisib Duvelisib The metabolism of Ruxolitinib can be decreased when combined with Duvelisib.
Stiripentol Stiripentol The metabolism of Ruxolitinib can be decreased when combined with Stiripentol.
Gilteritinib Gilteritinib The metabolism of Ruxolitinib can be decreased when combined with Gilteritinib.
Methoxy Polyethylene Glycol-Epoetin Beta Injection Methoxy Polyethylene Glycol-Epoetin Beta Injection The risk or severity of Thrombosis can be increased when Methoxy polyethylene glycol-epoetin beta is combined with Ruxolitinib.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The metabolism of Ruxolitinib can be increased when combined with Paclitaxel.
Rifamycin Rifamycin The metabolism of Ruxolitinib can be increased when combined with Rifamycin.
Prucalopride Prucalopride The metabolism of Ruxolitinib can be decreased when combined with Prucalopride.
Ravulizumab-cwvz Injection Ravulizumab-cwvz Injection The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Ravulizumab.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Emapalumab can be increased when combined with Ruxolitinib.
Siponimod Siponimod The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Siponimod.
Acyclovir Ophthalmic Acyclovir Ophthalmic Acyclovir may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Caplacizumab-yhdp Injection Caplacizumab-yhdp Injection The risk or severity of bleeding can be increased when Caplacizumab is combined with Ruxolitinib.
Risankizumab-rzaa Injection Risankizumab-rzaa Injection The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Risankizumab.
Alpelisib Alpelisib The metabolism of Ruxolitinib can be increased when combined with Alpelisib.
Cladribine Cladribine The risk or severity of adverse effects can be increased when Cladribine is combined with Ruxolitinib.
Solriamfetol Solriamfetol Ruxolitinib may decrease the excretion rate of Solriamfetol which could result in a higher serum level.
Triclabendazole Triclabendazole The metabolism of Ruxolitinib can be decreased when combined with Triclabendazole.
Pitolisant Pitolisant The serum concentration of Ruxolitinib can be decreased when it is combined with Pitolisant.
Lefamulin Lefamulin The serum concentration of Ruxolitinib can be increased when it is combined with Lefamulin.
Phenytoin Injection Phenytoin Injection The metabolism of Ruxolitinib can be increased when combined with Phenytoin.
Fosphenytoin Injection Fosphenytoin Injection The metabolism of Ruxolitinib can be increased when combined with Fosphenytoin.
Voxelotor Voxelotor The serum concentration of Ruxolitinib can be increased when it is combined with Voxelotor.
Tazemetostat Tazemetostat The metabolism of Ruxolitinib can be decreased when combined with Tazemetostat.
Cenobamate Cenobamate The serum concentration of Ruxolitinib can be decreased when it is combined with Cenobamate.
Ozanimod Ozanimod The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Ozanimod.
Tucatinib Tucatinib The metabolism of Tucatinib can be decreased when combined with Ruxolitinib.
Octreotide Octreotide The serum concentration of Octreotide can be increased when it is combined with Ruxolitinib.
Pralsetinib Pralsetinib The metabolism of Ruxolitinib can be increased when combined with Pralsetinib.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Ruxolitinib can be decreased when it is combined with Satralizumab.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Ruxolitinib can be decreased when combined with Drospirenone.
Viloxazine Viloxazine Ruxolitinib may decrease the excretion rate of Viloxazine which could result in a higher serum level.
Vitamin E (Alpha-Tocopherol) Vitamin E (Alpha-Tocopherol) The metabolism of Ruxolitinib can be increased when combined with Vitamin E.
Tobramycin Injection Tobramycin Injection Tobramycin may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Fenoprofen Fenoprofen Fenoprofen may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Indomethacin Indomethacin The risk or severity of adverse effects can be increased when Indomethacin is combined with Ruxolitinib.
Mefenamic Acid Mefenamic Acid Mefenamic acid may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Naproxen Naproxen Naproxen may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Tolmetin Tolmetin Tolmetin may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Sulindac Sulindac Sulindac may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Isotretinoin Isotretinoin Isotretinoin may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Sucralfate Sucralfate Sucralfate may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Hydroxyurea Hydroxyurea The risk or severity of adverse effects can be increased when Hydroxyurea is combined with Ruxolitinib.
Floxuridine Floxuridine The risk or severity of adverse effects can be increased when Floxuridine is combined with Ruxolitinib.
Phenobarbital Phenobarbital The metabolism of Ruxolitinib can be increased when combined with Phenobarbital.
Metaxalone Metaxalone Metaxalone may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Methotrexate Injection Methotrexate Injection The risk or severity of adverse effects can be increased when Methotrexate is combined with Ruxolitinib.
Primidone Primidone The metabolism of Ruxolitinib can be increased when combined with Primidone.
Methsuximide Methsuximide Ruxolitinib may increase the bradycardic activities of Methsuximide.
Chlorpromazine Chlorpromazine The metabolism of Ruxolitinib can be increased when combined with Chlorpromazine.
Diazepam Diazepam The metabolism of Ruxolitinib can be decreased when combined with Diazepam.
Oxazepam Oxazepam Oxazepam may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Flurazepam Flurazepam Flurazepam may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Clorazepate Clorazepate Clorazepic acid may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Lorazepam Lorazepam The metabolism of Ruxolitinib can be decreased when combined with Lorazepam.
Carmustine Carmustine The risk or severity of adverse effects can be increased when Carmustine is combined with Ruxolitinib.
Amantadine Amantadine Amantadine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Codeine Codeine Codeine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Bromocriptine Bromocriptine The metabolism of Ruxolitinib can be decreased when combined with Bromocriptine.
Tranylcypromine Tranylcypromine The metabolism of Ruxolitinib can be decreased when combined with Tranylcypromine.
Phenelzine Phenelzine The metabolism of Ruxolitinib can be decreased when combined with Phenelzine.
Procarbazine Procarbazine The risk or severity of adverse effects can be increased when Procarbazine is combined with Ruxolitinib.
Tetracycline Tetracycline The metabolism of Ruxolitinib can be decreased when combined with Tetracycline.
Thioguanine Thioguanine The risk or severity of adverse effects can be increased when Tioguanine is combined with Ruxolitinib.
Prochlorperazine Prochlorperazine The metabolism of Ruxolitinib can be decreased when combined with Prochlorperazine.
Bleomycin Bleomycin The risk or severity of adverse effects can be increased when Bleomycin is combined with Ruxolitinib.
Sulfadiazine Sulfadiazine Sulfadiazine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Methadone Methadone The metabolism of Ruxolitinib can be increased when combined with Methadone.
Oxybutynin Oxybutynin The metabolism of Ruxolitinib can be decreased when combined with Oxybutynin.
Benztropine Benztropine Benzatropine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Maprotiline Maprotiline Maprotiline may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Ibuprofen Ibuprofen Ibuprofen may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Orphenadrine Orphenadrine The metabolism of Ruxolitinib can be decreased when combined with Orphenadrine.
Azathioprine Azathioprine The risk or severity of adverse effects can be increased when Azathioprine is combined with Ruxolitinib.
Phentermine Phentermine The metabolism of Ruxolitinib can be decreased when combined with Phentermine.
Methylphenidate Methylphenidate Methylphenidate may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Sulfasalazine Sulfasalazine The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Ruxolitinib.
Hydrocortisone Hydrocortisone The metabolism of Ruxolitinib can be increased when combined with Hydrocortisone.
Lomustine Lomustine The risk or severity of adverse effects can be increased when Lomustine is combined with Ruxolitinib.
Doxorubicin Doxorubicin The metabolism of Ruxolitinib can be decreased when combined with Doxorubicin.
Cytarabine Cytarabine The risk or severity of adverse effects can be increased when Cytarabine is combined with Ruxolitinib.
Mechlorethamine Mechlorethamine The risk or severity of adverse effects can be increased when Mechlorethamine is combined with Ruxolitinib.
Dactinomycin Dactinomycin The risk or severity of adverse effects can be increased when Dactinomycin is combined with Ruxolitinib.
Phenazopyridine Phenazopyridine Phenazopyridine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Carbamazepine Carbamazepine The metabolism of Ruxolitinib can be increased when combined with Carbamazepine.
Methyldopa Methyldopa Ruxolitinib may increase the bradycardic activities of Methyldopa.
Clonidine Clonidine Ruxolitinib may increase the bradycardic activities of Clonidine.
Hydralazine Hydralazine The metabolism of Ruxolitinib can be decreased when combined with Hydralazine.
Cimetidine Cimetidine The metabolism of Ruxolitinib can be decreased when combined with Cimetidine.
Gentamicin Injection Gentamicin Injection Gentamicin may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Warfarin Warfarin The metabolism of Ruxolitinib can be increased when combined with Warfarin.
Clonazepam Clonazepam Clonazepam may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Loperamide Loperamide The metabolism of Ruxolitinib can be decreased when combined with Loperamide.
Promethazine Promethazine Promethazine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Meclofenamate Meclofenamate Meclofenamic acid may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Daunorubicin Daunorubicin The metabolism of Ruxolitinib can be decreased when combined with Daunorubicin.
Nitrofurantoin Nitrofurantoin Nitrofurantoin may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Griseofulvin Griseofulvin The metabolism of Ruxolitinib can be increased when combined with Griseofulvin.
Digoxin Digoxin Ruxolitinib may increase the bradycardic activities of Digoxin.
Chloroquine Chloroquine Chloroquine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Quinine Quinine The metabolism of Ruxolitinib can be increased when combined with Quinine.
Ethosuximide Ethosuximide Ruxolitinib may increase the bradycardic activities of Ethosuximide.
Calcitriol Calcitriol The metabolism of Ruxolitinib can be increased when combined with Calcitriol.
Triamterene Triamterene Triamterene may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Sulfinpyrazone Sulfinpyrazone The metabolism of Ruxolitinib can be increased when combined with Sulfinpyrazone.
Chlorothiazide Chlorothiazide Chlorothiazide may increase the excretion rate of Ruxolitinib which could result in a lower serum level and potentially a reduction in efficacy.
Chlorthalidone Chlorthalidone Chlorthalidone may increase the excretion rate of Ruxolitinib which could result in a lower serum level and potentially a reduction in efficacy.
Metolazone Metolazone Metolazone may increase the excretion rate of Ruxolitinib which could result in a lower serum level and potentially a reduction in efficacy.
Isosorbide Isosorbide Isosorbide may increase the excretion rate of Ruxolitinib which could result in a lower serum level and potentially a reduction in efficacy.
Secobarbital Secobarbital The metabolism of Ruxolitinib can be increased when combined with Secobarbital.
Desipramine Desipramine The metabolism of Ruxolitinib can be decreased when combined with Desipramine.
Amitriptyline Amitriptyline Amitriptyline may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Imipramine Imipramine Imipramine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Probenecid Probenecid The metabolism of Ruxolitinib can be increased when combined with Probenecid.
Quinidine Quinidine The metabolism of Ruxolitinib can be decreased when combined with Quinidine.
Procainamide Procainamide Ruxolitinib may decrease the excretion rate of Procainamide which could result in a higher serum level.
Isoniazid Isoniazid The metabolism of Ruxolitinib can be decreased when combined with Isoniazid.
Pyrazinamide Pyrazinamide Pyrazinamide may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Rifampin Rifampin The metabolism of Ruxolitinib can be increased when combined with Rifampicin.
Disopyramide Disopyramide Disopyramide may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Valproic Acid Valproic Acid The metabolism of Ruxolitinib can be decreased when combined with Valproic acid.
Tamoxifen Tamoxifen The metabolism of Ruxolitinib can be increased when combined with Tamoxifen.
Mitomycin Mitomycin The risk or severity of adverse effects can be increased when Mitomycin is combined with Ruxolitinib.
Butabarbital Butabarbital Butabarbital may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Levothyroxine Levothyroxine The therapeutic efficacy of Levothyroxine can be decreased when used in combination with Ruxolitinib.
Liothyronine Liothyronine The therapeutic efficacy of Ruxolitinib can be decreased when used in combination with Liothyronine.
Methimazole Methimazole The metabolism of Ruxolitinib can be decreased when combined with Methimazole.
Propylthiouracil Propylthiouracil The therapeutic efficacy of Ruxolitinib can be decreased when used in combination with Propylthiouracil.
Chlorpropamide Chlorpropamide Chlorpropamide may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Tolbutamide Tolbutamide Tolbutamide may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Tolazamide Tolazamide Tolazamide may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Niacin Niacin The metabolism of Ruxolitinib can be decreased when combined with Niacin.
Baclofen Baclofen Baclofen may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Ethambutol Ethambutol Ethambutol may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Methyclothiazide Methyclothiazide Methyclothiazide may increase the excretion rate of Ruxolitinib which could result in a lower serum level and potentially a reduction in efficacy.
Hydrochlorothiazide Hydrochlorothiazide Hydrochlorothiazide may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Chlorzoxazone Chlorzoxazone Chlorzoxazone may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Pyridoxine Pyridoxine Pyridoxine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Folic Acid Folic Acid Folic acid may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Danazol Danazol The metabolism of Ruxolitinib can be decreased when combined with Danazol.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) Ruxolitinib may increase the bradycardic activities of Propranolol.
Spironolactone Spironolactone Spironolactone may increase the excretion rate of Ruxolitinib which could result in a lower serum level and potentially a reduction in efficacy.
Amphotericin B Injection Amphotericin B Injection The metabolism of Ruxolitinib can be decreased when combined with Amphotericin B.
Mercaptopurine Mercaptopurine The risk or severity of adverse effects can be increased when Mercaptopurine is combined with Ruxolitinib.
Phytonadione Phytonadione Phylloquinone may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Amikacin Injection Amikacin Injection Amikacin may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Nadolol Nadolol Ruxolitinib may increase the bradycardic activities of Nadolol.
Allopurinol Allopurinol The risk or severity of adverse effects can be increased when Allopurinol is combined with Ruxolitinib.
Flavoxate Flavoxate Flavoxate may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Fluorouracil Injection Fluorouracil Injection The risk or severity of adverse effects can be increased when Fluorouracil is combined with Ruxolitinib.
Colchicine Colchicine The metabolism of Ruxolitinib can be increased when combined with Colchicine.
Cefaclor Cefaclor Cefaclor may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Cefadroxil Cefadroxil Cefadroxil may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Cefazolin Injection Cefazolin Injection Cefazolin may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Cephalexin Cephalexin The metabolism of Ruxolitinib can be decreased when combined with Cephalexin.
Cefoxitin Injection Cefoxitin Injection Cefoxitin may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Dacarbazine Dacarbazine The risk or severity of adverse effects can be increased when Dacarbazine is combined with Ruxolitinib.
Acetazolamide Acetazolamide The metabolism of Ruxolitinib can be decreased when combined with Acetazolamide.
Cefotaxime Injection Cefotaxime Injection Cefotaxime may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Calcitonin Salmon Injection Calcitonin Salmon Injection The therapeutic efficacy of Ruxolitinib can be decreased when used in combination with Salmon calcitonin.
Bacillus Calmette-Guerin (BCG) Vaccine Bacillus Calmette-Guerin (BCG) Vaccine The risk or severity of infection can be increased when Bacillus calmette-guerin substrain tice live antigen is combined with Ruxolitinib.
Ketoconazole Ketoconazole The metabolism of Ruxolitinib can be decreased when combined with Ketoconazole.
Pyrantel Pyrantel Ruxolitinib may decrease the excretion rate of Pyrantel which could result in a higher serum level.
Thiotepa Injection Thiotepa Injection The risk or severity of adverse effects can be increased when Thiotepa is combined with Ruxolitinib.
Vincristine Injection Vincristine Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Ruxolitinib.
Dipyridamole Dipyridamole The risk or severity of bleeding can be increased when Dipyridamole is combined with Ruxolitinib.
Vinblastine Vinblastine The metabolism of Ruxolitinib can be increased when combined with Vinblastine.
Ethacrynic Acid Ethacrynic Acid Etacrynic acid may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Colistimethate Injection Colistimethate Injection Colistimethate may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Metoprolol Metoprolol Ruxolitinib may increase the bradycardic activities of Metoprolol.
Aspirin Aspirin Acetylsalicylic acid may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Salsalate Salsalate Salsalate may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Chlorambucil Chlorambucil The risk or severity of adverse effects can be increased when Chlorambucil is combined with Ruxolitinib.
Alprazolam Alprazolam Alprazolam may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Temazepam Temazepam Temazepam may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Triazolam Triazolam Triazolam may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Dicyclomine Dicyclomine Dicyclomine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Propantheline Propantheline Propantheline may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Trimethoprim Trimethoprim Trimethoprim may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Diltiazem Diltiazem Ruxolitinib may increase the bradycardic activities of Diltiazem.
Nifedipine Nifedipine Ruxolitinib may increase the bradycardic activities of Nifedipine.
Timolol Timolol Ruxolitinib may increase the bradycardic activities of Timolol.
Verapamil Verapamil Ruxolitinib may increase the bradycardic activities of Verapamil.
Atenolol Atenolol Ruxolitinib may increase the bradycardic activities of Atenolol.
Pindolol Pindolol Ruxolitinib may increase the bradycardic activities of Pindolol.
Cisplatin Injection Cisplatin Injection The risk or severity of adverse effects can be increased when Cisplatin is combined with Ruxolitinib.
Diflunisal Diflunisal Diflunisal may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Piroxicam Piroxicam Piroxicam may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Bumetanide Bumetanide Bumetanide may increase the excretion rate of Ruxolitinib which could result in a lower serum level and potentially a reduction in efficacy.
Streptozocin Streptozocin The risk or severity of adverse effects can be increased when Streptozocin is combined with Ruxolitinib.
Etoposide Etoposide The metabolism of Ruxolitinib can be increased when combined with Etoposide.
Glyburide Glyburide The metabolism of Ruxolitinib can be decreased when combined with Glyburide.
Glipizide Glipizide Glipizide may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Indapamide Indapamide Indapamide may increase the excretion rate of Ruxolitinib which could result in a lower serum level and potentially a reduction in efficacy.
Amoxicillin Amoxicillin Amoxicillin may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Dicloxacillin Dicloxacillin The metabolism of Ruxolitinib can be increased when combined with Dicloxacillin.
Nafcillin Injection Nafcillin Injection The metabolism of Ruxolitinib can be increased when combined with Nafcillin.
Oxacillin Injection Oxacillin Injection Oxacillin may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Pentoxifylline Pentoxifylline Pentoxifylline may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Pentamidine Injection Pentamidine Injection Pentamidine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Ceftriaxone Injection Ceftriaxone Injection Ceftriaxone may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Labetalol Labetalol Ruxolitinib may increase the bradycardic activities of Labetalol.
Auranofin Auranofin Auranofin may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Leuprolide Injection Leuprolide Injection Leuprolide may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Gemfibrozil Gemfibrozil Gemfibrozil may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Dipivefrin Ophthalmic Dipivefrin Ophthalmic Adefovir dipivoxil may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Ceftazidime Injection Ceftazidime Injection Ceftazidime may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Ketoprofen Ketoprofen Ketoprofen may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Cefotetan Injection Cefotetan Injection Cefotetan may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Pimozide Pimozide The metabolism of Ruxolitinib can be decreased when combined with Pimozide.
Flurbiprofen Flurbiprofen Flurbiprofen may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Amiodarone Amiodarone Ruxolitinib may increase the bradycardic activities of Amiodarone.
Aztreonam Injection Aztreonam Injection Aztreonam may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Buspirone Buspirone Buspirone may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Lovastatin Lovastatin The metabolism of Ruxolitinib can be decreased when combined with Lovastatin.
Ciprofloxacin Ciprofloxacin The metabolism of Ruxolitinib can be decreased when combined with Ciprofloxacin.
Mesalamine Mesalamine Mesalazine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Diclofenac Diclofenac Diclofenac may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Nimodipine Nimodipine Ruxolitinib may increase the bradycardic activities of Nimodipine.
Interferon Alfa-2b Injection Interferon Alfa-2b Injection The risk or severity of adverse effects can be increased when Interferon alfa-2b is combined with Ruxolitinib.
Clozapine Clozapine The risk or severity of neutropenia can be increased when Ruxolitinib is combined with Clozapine.
Estazolam Estazolam Estazolam may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Idarubicin Idarubicin The risk or severity of adverse effects can be increased when Idarubicin is combined with Ruxolitinib.
Didanosine Didanosine Didanosine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Fludarabine Injection Fludarabine Injection The risk or severity of adverse effects can be increased when Fludarabine is combined with Ruxolitinib.
Pentostatin Injection Pentostatin Injection The risk or severity of adverse effects can be increased when Pentostatin is combined with Ruxolitinib.
Clarithromycin Clarithromycin The metabolism of Ruxolitinib can be decreased when combined with Clarithromycin.
Etodolac Etodolac Etodolac may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Felodipine Felodipine Ruxolitinib may increase the bradycardic activities of Felodipine.
Fosinopril Fosinopril Fosinopril may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Nabumetone Nabumetone Nabumetone may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Epoetin Alfa, Injection Epoetin Alfa, Injection The risk or severity of Thrombosis can be increased when Erythropoietin is combined with Ruxolitinib.
Amlodipine Amlodipine Ruxolitinib may increase the bradycardic activities of Amlodipine.
Teniposide Injection Teniposide Injection The metabolism of Ruxolitinib can be decreased when combined with Teniposide.
Itraconazole Itraconazole The metabolism of Ruxolitinib can be decreased when combined with Itraconazole.
Lisinopril Lisinopril Lisinopril may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Oxaprozin Oxaprozin Oxaprozin may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Rifabutin Rifabutin The metabolism of Ruxolitinib can be increased when combined with Rifabutin.
Sotalol Sotalol Ruxolitinib may increase the bradycardic activities of Sotalol.
Bisoprolol Bisoprolol Ruxolitinib may increase the bradycardic activities of Bisoprolol.
Doxazosin Doxazosin The metabolism of Ruxolitinib can be decreased when combined with Doxazosin.
Isradipine Isradipine Ruxolitinib may increase the bradycardic activities of Isradipine.
Omeprazole Omeprazole The metabolism of Ruxolitinib can be increased when combined with Omeprazole.
Cisapride Cisapride The metabolism of Ruxolitinib can be decreased when combined with Cisapride.
Fluvastatin Fluvastatin The metabolism of Ruxolitinib can be decreased when combined with Fluvastatin.
Venlafaxine Venlafaxine Venlafaxine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Famciclovir Famciclovir The metabolism of Ruxolitinib can be decreased when combined with Famciclovir.
Fluvoxamine Fluvoxamine The metabolism of Ruxolitinib can be decreased when combined with Fluvoxamine.
Nefazodone Nefazodone The metabolism of Ruxolitinib can be decreased when combined with Nefazodone.
Lamotrigine Lamotrigine Ruxolitinib may increase the bradycardic activities of Lamotrigine.
Losartan Losartan The metabolism of Ruxolitinib can be decreased when combined with Losartan.
Valacyclovir Valacyclovir Valaciclovir may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Tramadol Tramadol Tramadol may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Vinorelbine Injection Vinorelbine Injection The risk or severity of adverse effects can be increased when Vinorelbine is combined with Ruxolitinib.
Carboplatin Injection Carboplatin Injection The risk or severity of adverse effects can be increased when Carboplatin is combined with Ruxolitinib.
Lansoprazole Lansoprazole The metabolism of Ruxolitinib can be increased when combined with Lansoprazole.
Ifosfamide Injection Ifosfamide Injection The metabolism of Ruxolitinib can be increased when combined with Ifosfamide.
Pegaspargase Injection Pegaspargase Injection The risk or severity of adverse effects can be increased when Pegaspargase is combined with Ruxolitinib.
Nicardipine Nicardipine Ruxolitinib may increase the bradycardic activities of Nicardipine.
Bupropion Bupropion Bupropion may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Ticlopidine Ticlopidine The metabolism of Ruxolitinib can be decreased when combined with Ticlopidine.
Saquinavir Saquinavir The metabolism of Saquinavir can be decreased when combined with Ruxolitinib.
Metformin Metformin Metformin may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Dalteparin Injection Dalteparin Injection The risk or severity of bleeding can be increased when Dalteparin is combined with Ruxolitinib.
Nisoldipine Nisoldipine Ruxolitinib may increase the bradycardic activities of Nisoldipine.
Lamivudine Lamivudine Lamivudine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Acarbose Acarbose Acarbose may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Gemcitabine Injection Gemcitabine Injection The risk or severity of adverse effects can be increased when Gemcitabine is combined with Ruxolitinib.
Ritonavir Ritonavir The metabolism of Ruxolitinib can be decreased when combined with Ritonavir.
Docetaxel Injection Docetaxel Injection The metabolism of Ruxolitinib can be decreased when combined with Docetaxel.
Cidofovir Injection Cidofovir Injection Cidofovir may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Meropenem Injection Meropenem Injection Meropenem may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Clomipramine Clomipramine Clomipramine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Zafirlukast Zafirlukast The metabolism of Ruxolitinib can be decreased when combined with Zafirlukast.
Fosfomycin Fosfomycin Fosfomycin may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Mirtazapine Mirtazapine The metabolism of Ruxolitinib can be decreased when combined with Mirtazapine.
Topiramate Topiramate The metabolism of Ruxolitinib can be increased when combined with Topiramate.
Pramipexole Pramipexole Pramipexole may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Donepezil Donepezil Ruxolitinib may increase the bradycardic activities of Donepezil.
Azithromycin Azithromycin The metabolism of Ruxolitinib can be decreased when combined with Azithromycin.
Carvedilol Carvedilol Ruxolitinib may increase the bradycardic activities of Carvedilol.
Nilutamide Nilutamide Nilutamide may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Flutamide Flutamide Flutamide may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Bicalutamide Bicalutamide The metabolism of Ruxolitinib can be decreased when combined with Bicalutamide.
Propafenone Propafenone Ruxolitinib may increase the bradycardic activities of Propafenone.
Raloxifene Raloxifene The metabolism of Ruxolitinib can be decreased when combined with Raloxifene.
Irbesartan Irbesartan The metabolism of Ruxolitinib can be decreased when combined with Irbesartan.
Tamsulosin Tamsulosin Tamsulosin may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Quetiapine Quetiapine Quetiapine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Cefepime Injection Cefepime Injection Cefepime may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Cefprozil Cefprozil Cefprozil may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Cefpodoxime Cefpodoxime Cefpodoxime may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Cetirizine Cetirizine Cetirizine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Paroxetine Paroxetine The metabolism of Ruxolitinib can be decreased when combined with Paroxetine.
Tolcapone Tolcapone Tolcapone may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Citalopram Citalopram The metabolism of Ruxolitinib can be decreased when combined with Citalopram.
Capecitabine Capecitabine The risk or severity of adverse effects can be increased when Capecitabine is combined with Ruxolitinib.
Efavirenz Efavirenz The metabolism of Ruxolitinib can be decreased when combined with Efavirenz.
Abacavir Abacavir Abacavir may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Trastuzumab Injection Trastuzumab Injection Trastuzumab may increase the neutropenic activities of Ruxolitinib.
Celecoxib Celecoxib Celecoxib may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Rosiglitazone Rosiglitazone Rosiglitazone may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Tolterodine Tolterodine Tolterodine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Thalidomide Thalidomide The risk or severity of adverse effects can be increased when Thalidomide is combined with Ruxolitinib.
Oseltamivir Oseltamivir Oseltamivir may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Balsalazide Balsalazide Balsalazide may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Nateglinide Nateglinide Nateglinide may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Galantamine Galantamine Ruxolitinib may increase the bradycardic activities of Galantamine.
Rabeprazole Rabeprazole The metabolism of Ruxolitinib can be decreased when combined with Rabeprazole.
Terbinafine Terbinafine The metabolism of Ruxolitinib can be increased when combined with Terbinafine.

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