Glyburide

Glyburide is used along with diet and exercise, and sometimes with other medications, to treat type 2 diabetes (condition in which the body does not use insulin normally and, therefore, cannot control the amount of sugar in the blood). Glyburide is in a class of medications called sulfonylureas. Glyburide lowers blood sugar by causing the pancreas to produce insulin (a natural substance that is needed to break down sugar in the body) and helping the body use insulin efficiently. This medication will only help lower blood sugar in people whose bodies produce insulin naturally. Glyburide is not used to treat type 1 diabetes (condition in which the body does not produce insulin and, therefore, cannot control the amount of sugar in the blood) or diabetic ketoacidosis (a serious condition that may occur if high blood sugar is not treated).

Over time, people who have diabetes and high blood sugar can develop serious or life-threatening complications, including heart disease, stroke, kidney problems, nerve damage, and eye problems. Taking medication(s), making lifestyle changes (e.g., diet, exercise, quitting smoking), and regularly checking your blood sugar may help to manage your diabetes and improve your health. This therapy may also decrease your chances of having a heart attack, stroke, or other diabetes-related complications such as kidney failure, nerve damage (numb, cold legs or feet; decreased sexual ability in men and women), eye problems, including changes or loss of vision, or gum disease. Your doctor and other healthcare providers will talk to you about the best way to manage your diabetes.

Glyburide comes as a tablet to take by mouth. It is usually taken once a day with breakfast or the first main meal of the day. However, in some cases your doctor may tell you to take glyburide twice a day. To help you remember to take glyburide, take it at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take glyburide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor will probably start you on a low dose of glyburide and gradually increase your dose if needed. After you have taken glyburide for some time, glyburide may not control your blood sugar as well as it did at the beginning of your treatment. Your doctor may adjust the dose of your medication as needed so that the medication will work best for you. Be sure to tell your doctor how you are feeling and if your blood sugar test results have been higher or lower than normal at any time during your treatment.

Glyburide helps control blood sugar but does not cure diabetes. Continue to take glyburide even if you feel well. Do not stop taking glyburide without talking to your doctor.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking glyburide,

• tell your doctor and pharmacist if you are allergic to glyburide, any other medications, or any of the ingredients in glyburide. Ask your pharmacist for a list of the ingredients.

• tell your doctor if you are taking bosentan (Tracleer). Your doctor may tell you not to take glyburide if you are taking this medication.

• tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril, (Aceon), quinapril (Accupril), ramipril (Altace), and trandolapril (Mavik); anticoagulants ('blood thinners') such as warfarin (Coumadin); aspirin and other nonsteroidal anti-inflammatory medications (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn); beta blockers such as atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), and propranolol (Inderal); calcium channel blockers such as amlodipine (Norvasc), diltiazem (Cardizem, Dilacor, Tiazac, others), felodipine (Plendil), isradipine (DynaCirc), nicardipine (Cardene), nifedipine (Adalat, Procardia), nimodipine (Nimotop), nisoldipine (Sular), and verapamil (Calan, Isoptin, Verelan); chloramphenicol; clarithromycin (Biaxin); cyclosporine (Neoral, Sandimmune); disopyramide (Norpace); diuretics ('water pills'); fluconazole (Diflucan), fluoxetine (Prozac, Sarafem); gemfibrozil (Lopid), hormone replacement therapy and hormonal contraceptives (birth control pills, patches, rings, implants, and injections); insulin or other medications to treat high blood sugar or diabetes; isoniazid (INH); MAO inhibitors such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate); medications for asthma and colds; medications for mental illness and nausea; miconazole (Monistat); niacin; oral steroids such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), and prednisone (Deltasone); phenytoin (Dilantin); probenecid (Benemid); quinolone and fluoroquinolone antibiotics such as cinoxacin (Cinobac), ciprofloxacin (Cipro), enoxacin (Penetrex), gatifloxacin (Tequin), levofloxacin (Levaquin), lomefloxacin (Maxaquin), moxifloxacin (Avelox), nalidixic acid (NegGram), norfloxacin (Noroxin), ofloxacin (Floxin), sparfloxacin (Zagam), trovafloxacin and alatrofloxacin combination (Trovan); rifampin; salicylate pain relievers such as choline magnesium trisalicylate, choline salicylate (Arthropan), diflunisal (Dolobid), magnesium salicylate (Doan's, others), and salsalate (Argesic, Disalcid, Salgesic); sulfa antibiotics such as co-trimoxazole (Bactrim, Septra); sulfasalazine (Azulfidine); and thyroid medications. Also be sure to tell your doctor or pharmacist if you stop taking any medications while taking glyburide. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

• tell your doctor if you have or have ever had G6PD deficiency (an inherited condition causing premature destruction of red blood cells or hemolytic anemia); if you have hormone disorders involving the adrenal, pituitary, or thyroid gland; or if you have heart, kidney, or liver disease.

• tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking glyburide, call your doctor.

• talk to your doctor about the risks and benefits of taking glyburide if you are 65 years of age or older. Older adults should not usually take glyburide because it is not as safe or effective as other medications that can be used to treat the same condition.

• if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking glyburide.

• ask your doctor about the safe use of alcoholic beverages while you are taking glyburide. Alcohol can make the side effects from glyburide worse. Consuming alcohol while taking glyburide also rarely may cause symptoms such as flushing (reddening of the face), headache, nausea, vomiting, chest pain, weakness, blurred vision, mental confusion, sweating, choking, breathing difficulty, and anxiety.

• plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Glyburide may make your skin sensitive to sunlight.

• ask your doctor what to do if you get sick, develop an infection or fever, experience unusual stress, or are injured. These conditions can affect your blood sugar and the amount of glyburide you may need.

Be sure to follow all exercise and dietary recommendations made by your doctor or dietitian. It is important to eat a healthy diet, exercise regularly, and lose weight if necessary.

Before you start to take glyburide, ask you doctor what you should do if you forget to take a dose. Write these directions down so that you can refer to them later.

As a general rule, take the missed dose as soon as you remember it. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

This medication may cause changes in your blood sugar. You should know the symptoms of low and high blood sugar and what to do if you have these symptoms.

• Glyburide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • nausea

  • upper abdominal fullness

  • heartburn

  • rash

• Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:

  • yellowing of the skin or eyes

  • light-colored stools

  • dark urine

  • pain in the upper right part of the stomach

  • unusual bruising or bleeding

  • diarrhea

  • fever

  • sore throat

  • swelling of the eyes, face, lips, tongue, or throat

• Glyburide may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

• If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

• In one study, people who took a medication similar to glyburide to treat their diabetes were more likely to die of heart problems than people who were treated with insulin and diet changes. Talk to your doctor about the risks of taking glyburide.

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include hypoglycemia symptoms as well as the following:

• seizures

• loss of consciousness

Keep all appointments with your doctor and the laboratory. Your fasting blood sugar levels and glycosylated hemoglobin (HbA1c) should be checked regularly to determine your response to glyburide. Your doctor may order other lab tests to check your response to glyburide. Your doctor will also tell you how to check your response to this medication by measuring your blood sugar levels at home. Follow these instructions carefully.

You should always wear a diabetic identification bracelet to be sure you get proper treatment in an emergency.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug	Interaction
Moxifloxacin	Moxifloxacin The therapeutic efficacy of Glyburide can be increased when used in combination with Moxifloxacin.
Repaglinide	Repaglinide Glyburide may decrease the excretion rate of Repaglinide which could result in a higher serum level.
Montelukast	Montelukast The metabolism of Montelukast can be decreased when combined with Glyburide.
Insulin Glargine (rDNA origin) Injection	Insulin Glargine (rDNA origin) Injection The risk or severity of hypoglycemia can be increased when Insulin glargine is combined with Glyburide.
Leflunomide	Leflunomide The metabolism of Leflunomide can be decreased when combined with Glyburide.
Delavirdine	Delavirdine The metabolism of Glyburide can be decreased when combined with Delavirdine.
Nevirapine	Nevirapine The metabolism of Glyburide can be decreased when combined with Nevirapine.
Atorvastatin	Atorvastatin The metabolism of Atorvastatin can be decreased when combined with Glyburide.
Aminophylline	Aminophylline The metabolism of Aminophylline can be decreased when combined with Glyburide.
Candesartan	Candesartan The metabolism of Candesartan can be decreased when combined with Glyburide.
Cilostazol	Cilostazol The metabolism of Cilostazol can be decreased when combined with Glyburide.
Clopidogrel	Clopidogrel The metabolism of Glyburide can be decreased when combined with Clopidogrel.
Erythromycin and Sulfisoxazole	Erythromycin and Sulfisoxazole The risk or severity of liver damage can be increased when Erythromycin is combined with Glyburide.
Estrogen and Progestin (Oral Contraceptives)	Estrogen and Progestin (Oral Contraceptives) The therapeutic efficacy of Conjugated estrogens can be decreased when used in combination with Glyburide.
Fenofibrate	Fenofibrate Glyburide may decrease the excretion rate of Fenofibrate which could result in a higher serum level.
Miglitol	Miglitol The risk or severity of hypoglycemia can be increased when Miglitol is combined with Glyburide.
Olsalazine	Olsalazine Olsalazine may increase the hypoglycemic activities of Glyburide.
Penbutolol	Penbutolol The therapeutic efficacy of Glyburide can be decreased when used in combination with Acebutolol.
Prednisone	Prednisone The risk or severity of hyperglycemia can be increased when Glyburide is combined with Prednisone.
Ranitidine	Ranitidine The serum concentration of Glyburide can be increased when it is combined with Ranitidine.
Reserpine	Reserpine The risk or severity of liver damage can be increased when Reserpine is combined with Glyburide.
Sumatriptan	Sumatriptan The therapeutic efficacy of Glyburide can be increased when used in combination with Sumatriptan.
Tacrolimus	Tacrolimus The serum concentration of Tacrolimus can be increased when it is combined with Glyburide.
Triamcinolone	Triamcinolone The risk or severity of hyperglycemia can be increased when Triamcinolone is combined with Glyburide.
Fluconazole Injection	Fluconazole Injection The serum concentration of Glyburide can be increased when it is combined with Fluconazole.
Hydromorphone Injection	Hydromorphone Injection The metabolism of Hydromorphone can be decreased when combined with Glyburide.
Levofloxacin Injection	Levofloxacin Injection The therapeutic efficacy of Glyburide can be increased when used in combination with Levofloxacin.
Meperidine Injection	Meperidine Injection The metabolism of Meperidine can be decreased when combined with Glyburide.
Methylprednisolone Injection	Methylprednisolone Injection The risk or severity of hyperglycemia can be increased when Glyburide is combined with Methylprednisolone.
Metronidazole Injection	Metronidazole Injection The metabolism of Glyburide can be decreased when combined with Metronidazole.
Zidovudine Injection	Zidovudine Injection The metabolism of Zidovudine can be decreased when combined with Glyburide.
Altretamine	Altretamine The therapeutic efficacy of Glyburide can be decreased when used in combination with Amphetamine.
Cyclosporine	Cyclosporine The therapeutic efficacy of Glyburide can be decreased when used in combination with Cyclosporine.
Ondansetron	Ondansetron The metabolism of Ondansetron can be decreased when combined with Glyburide.
Olanzapine	Olanzapine The metabolism of Glyburide can be decreased when combined with Olanzapine.
Alosetron	Alosetron The metabolism of Alosetron can be decreased when combined with Glyburide.
Dofetilide	Dofetilide The metabolism of Dofetilide can be decreased when combined with Glyburide.
Hydroxychloroquine	Hydroxychloroquine The therapeutic efficacy of Hydroxychloroquine can be increased when used in combination with Glyburide.
Meloxicam	Meloxicam The protein binding of Glyburide can be decreased when combined with Meloxicam.
Oxcarbazepine	Oxcarbazepine The metabolism of Glyburide can be increased when combined with Oxcarbazepine.
Pantoprazole	Pantoprazole Pantoprazole may decrease the excretion rate of Glyburide which could result in a higher serum level.
Telmisartan	Telmisartan Glyburide may decrease the excretion rate of Telmisartan which could result in a higher serum level.
Zaleplon	Zaleplon The metabolism of Glyburide can be decreased when combined with Zaleplon.
Anakinra	Anakinra The metabolism of Glyburide can be increased when combined with Anakinra.
Linezolid	Linezolid Linezolid may increase the hypoglycemic activities of Glyburide.
Trimipramine	Trimipramine The metabolism of Trimipramine can be decreased when combined with Glyburide.
Etanercept Injection	Etanercept Injection The metabolism of Glyburide can be increased when combined with Etanercept.
Modafinil	Modafinil The metabolism of Glyburide can be decreased when combined with Modafinil.
Tenofovir	Tenofovir The metabolism of Tenofovir can be decreased when combined with Glyburide.
Choline Magnesium Trisalicylate	Choline Magnesium Trisalicylate The protein binding of Glyburide can be decreased when combined with Choline magnesium trisalicylate.
Sirolimus	Sirolimus The metabolism of Sirolimus can be decreased when combined with Glyburide.
Dutasteride	Dutasteride The metabolism of Dutasteride can be decreased when combined with Glyburide.
Epinephrine Injection	Epinephrine Injection The therapeutic efficacy of Glyburide can be decreased when used in combination with Epinephrine.
Eplerenone	Eplerenone The metabolism of Glyburide can be decreased when combined with Eplerenone.
Escitalopram	Escitalopram The risk or severity of hypoglycemia can be increased when Glyburide is combined with Escitalopram.
Olmesartan	Olmesartan Glyburide may decrease the excretion rate of Olmesartan which could result in a higher serum level.
Zonisamide	Zonisamide The therapeutic efficacy of Glyburide can be increased when used in combination with Zonisamide.
Adalimumab Injection	Adalimumab Injection The metabolism of Glyburide can be increased when combined with Adalimumab.
Aripiprazole	Aripiprazole The metabolism of Aripiprazole can be decreased when combined with Glyburide.
Ezetimibe	Ezetimibe Glyburide may decrease the excretion rate of Ezetimibe which could result in a higher serum level.
Teriparatide Injection	Teriparatide Injection The therapeutic efficacy of Glyburide can be decreased when used in combination with Teriparatide.
Atazanavir	Atazanavir The metabolism of Atazanavir can be decreased when combined with Glyburide.
Eletriptan	Eletriptan The metabolism of Eletriptan can be decreased when combined with Glyburide.
Rosuvastatin	Rosuvastatin Glyburide may decrease the excretion rate of Rosuvastatin which could result in a higher serum level.
Vardenafil	Vardenafil The metabolism of Vardenafil can be decreased when combined with Glyburide.
Alfuzosin	Alfuzosin The metabolism of Alfuzosin can be decreased when combined with Glyburide.
Aprepitant	Aprepitant The metabolism of Glyburide can be decreased when combined with Aprepitant.
Memantine	Memantine The metabolism of Glyburide can be decreased when combined with Memantine.
Tadalafil	Tadalafil The metabolism of Glyburide can be decreased when combined with Tadalafil.
Fosamprenavir	Fosamprenavir The therapeutic efficacy of Glyburide can be decreased when used in combination with Fosamprenavir.
Gemifloxacin	Gemifloxacin The therapeutic efficacy of Glyburide can be increased when used in combination with Gemifloxacin.
Progesterone	Progesterone The therapeutic efficacy of Glyburide can be decreased when used in combination with Progesterone.
Apomorphine Injection	Apomorphine Injection The metabolism of Glyburide can be decreased when combined with Apomorphine.
Infliximab Injection	Infliximab Injection The metabolism of Glyburide can be increased when combined with Infliximab.
Oxandrolone	Oxandrolone The metabolism of Glyburide can be decreased when combined with Oxandrolone.
Protriptyline	Protriptyline Protriptyline may decrease the hypoglycemic activities of Glyburide.
Rifaximin	Rifaximin The metabolism of Glyburide can be increased when combined with Rifaximin.
Duloxetine	Duloxetine The metabolism of Duloxetine can be decreased when combined with Glyburide.
Norethindrone	Norethindrone The therapeutic efficacy of Glyburide can be decreased when used in combination with Norethisterone.
Tinidazole	Tinidazole Glyburide may decrease the excretion rate of Tinidazole which could result in a higher serum level.
Bosentan	Bosentan Glyburide may increase the hepatotoxic activities of Bosentan.
Cefditoren	Cefditoren The excretion of Cefdinir can be decreased when combined with Glyburide.
Erlotinib	Erlotinib The metabolism of Glyburide can be decreased when combined with Erlotinib.
Eszopiclone	Eszopiclone The metabolism of Eszopiclone can be decreased when combined with Glyburide.
Insulin Aspart (rDNA Origin) Injection	Insulin Aspart (rDNA Origin) Injection The risk or severity of hypoglycemia can be increased when Glyburide is combined with Insulin aspart.
Voriconazole	Voriconazole The serum concentration of Glyburide can be increased when it is combined with Voriconazole.
Dextroamphetamine	Dextroamphetamine The therapeutic efficacy of Glyburide can be decreased when used in combination with Amphetamine.
Peginterferon Alfa-2b (PEG-Intron)	Peginterferon Alfa-2b (PEG-Intron) The metabolism of Glyburide can be increased when combined with Peginterferon alfa-2b.
Pramlintide Injection	Pramlintide Injection The risk or severity of hypoglycemia can be increased when Glyburide is combined with Pramlintide.
Exenatide Injection	Exenatide Injection Exenatide may increase the hypoglycemic activities of Glyburide.
Isocarboxazid	Isocarboxazid Isocarboxazid may increase the hypoglycemic activities of Glyburide.
Ramelteon	Ramelteon The metabolism of Ramelteon can be decreased when combined with Glyburide.
Fentanyl	Fentanyl The metabolism of Fentanyl can be decreased when combined with Glyburide.
Pregabalin	Pregabalin The risk or severity of hypoglycemia can be increased when Pregabalin is combined with Glyburide.
Phenylephrine	Phenylephrine The therapeutic efficacy of Glyburide can be decreased when used in combination with Phenylephrine.
Tipranavir	Tipranavir The metabolism of Glyburide can be decreased when combined with Tipranavir.
Felbamate	Felbamate The metabolism of Glyburide can be decreased when combined with Felbamate.
Insulin Detemir (rDNA Origin) Injection	Insulin Detemir (rDNA Origin) Injection The risk or severity of hypoglycemia can be increased when Glyburide is combined with Insulin detemir.
Ranolazine	Ranolazine Glyburide may decrease the excretion rate of Ranolazine which could result in a higher serum level.
Abatacept Injection	Abatacept Injection The metabolism of Glyburide can be increased when combined with Abatacept.
Rasagiline	Rasagiline Rasagiline may increase the hypoglycemic activities of Glyburide.
Imatinib	Imatinib The metabolism of Glyburide can be decreased when combined with Imatinib.
Sitagliptin	Sitagliptin The risk or severity of hypoglycemia can be increased when Glyburide is combined with Sitagliptin.
Gefitinib	Gefitinib Gefitinib may decrease the excretion rate of Glyburide which could result in a higher serum level.
Paliperidone	Paliperidone The therapeutic efficacy of Paliperidone can be decreased when used in combination with Glyburide.
Bortezomib	Bortezomib The metabolism of Glyburide can be decreased when combined with Bortezomib.
Insulin Glulisine (rDNA origin) Injection	Insulin Glulisine (rDNA origin) Injection The risk or severity of hypoglycemia can be increased when Glyburide is combined with Insulin glulisine.
Bismuth Subsalicylate	Bismuth Subsalicylate Bismuth subsalicylate may increase the hypoglycemic activities of Glyburide.
Darunavir	Darunavir The therapeutic efficacy of Glyburide can be decreased when used in combination with Darunavir.
Lisdexamfetamine	Lisdexamfetamine The therapeutic efficacy of Glyburide can be decreased when used in combination with Lisdexamfetamine.
Nabilone	Nabilone The metabolism of Glyburide can be decreased when combined with Nabilone.
Retapamulin	Retapamulin The metabolism of Retapamulin can be decreased when combined with Glyburide.
Vorinostat	Vorinostat The therapeutic efficacy of Glyburide can be decreased when used in combination with Vorinostat.
Sorafenib	Sorafenib The metabolism of Glyburide can be decreased when combined with Sorafenib.
Sunitinib	Sunitinib The metabolism of Glyburide can be decreased when combined with Sunitinib.
Dronabinol	Dronabinol Dronabinol may decrease the excretion rate of Glyburide which could result in a higher serum level.
Lapatinib	Lapatinib The metabolism of Lapatinib can be decreased when combined with Glyburide.
Dasatinib	Dasatinib The metabolism of Dasatinib can be decreased when combined with Glyburide.
Armodafinil	Armodafinil The metabolism of Glyburide can be decreased when combined with Armodafinil.
Temsirolimus	Temsirolimus The metabolism of Temsirolimus can be decreased when combined with Glyburide.
Nilotinib	Nilotinib The metabolism of Glyburide can be decreased when combined with Nilotinib.
Bexarotene	Bexarotene The metabolism of Bexarotene can be decreased when combined with Glyburide.
Budesonide	Budesonide The risk or severity of hyperglycemia can be increased when Glyburide is combined with Budesonide.
Chloramphenicol Injection	Chloramphenicol Injection The metabolism of Glyburide can be decreased when combined with Chloramphenicol.
Etravirine	Etravirine The metabolism of Etravirine can be decreased when combined with Glyburide.
Arsenic Trioxide Injection	Arsenic Trioxide Injection The therapeutic efficacy of Glyburide can be decreased when used in combination with Arsenic trioxide.
Desvenlafaxine	Desvenlafaxine The risk or severity of hypoglycemia can be increased when Glyburide is combined with Desvenlafaxine.
Nebivolol	Nebivolol The therapeutic efficacy of Glyburide can be increased when used in combination with Nebivolol.
Tretinoin	Tretinoin The metabolism of Tretinoin can be decreased when combined with Glyburide.
Flecainide	Flecainide The metabolism of Glyburide can be decreased when combined with Flecainide.
Certolizumab Injection	Certolizumab Injection The metabolism of Glyburide can be increased when combined with Certolizumab pegol.
Ixabepilone Injection	Ixabepilone Injection The metabolism of Ixabepilone can be decreased when combined with Glyburide.
Irinotecan Injection	Irinotecan Injection The metabolism of Glyburide can be decreased when combined with Irinotecan.
Praziquantel	Praziquantel The metabolism of Praziquantel can be decreased when combined with Glyburide.
Rufinamide	Rufinamide The metabolism of Rufinamide can be decreased when combined with Glyburide.
Midazolam	Midazolam The serum concentration of Midazolam can be increased when it is combined with Glyburide.
Eltrombopag	Eltrombopag Eltrombopag may decrease the excretion rate of Glyburide which could result in a higher serum level.
Milnacipran	Milnacipran The risk or severity of hypoglycemia can be increased when Glyburide is combined with Milnacipran.
Dexlansoprazole	Dexlansoprazole The metabolism of Glyburide can be decreased when combined with Dexlansoprazole.
Betaxolol	Betaxolol The therapeutic efficacy of Glyburide can be increased when used in combination with Betaxolol.
Iloperidone	Iloperidone The metabolism of Iloperidone can be decreased when combined with Glyburide.
Prasugrel	Prasugrel The metabolism of Prasugrel can be decreased when combined with Glyburide.
Lacosamide	Lacosamide The metabolism of Lacosamide can be decreased when combined with Glyburide.
Everolimus	Everolimus The metabolism of Everolimus can be decreased when combined with Glyburide.
Tolvaptan (low blood sodium)	Tolvaptan (low blood sodium) The metabolism of Tolvaptan can be decreased when combined with Glyburide.
Dronedarone	Dronedarone The metabolism of Glyburide can be decreased when combined with Dronedarone.
Saxagliptin	Saxagliptin Saxagliptin may increase the hypoglycemic activities of Glyburide.
Romidepsin Injection	Romidepsin Injection The metabolism of Romidepsin can be decreased when combined with Glyburide.
Tapentadol	Tapentadol The metabolism of Tapentadol can be decreased when combined with Glyburide.
Golimumab Injection	Golimumab Injection The metabolism of Glyburide can be increased when combined with Golimumab.
Pazopanib	Pazopanib The metabolism of Pazopanib can be decreased when combined with Glyburide.
Asenapine	Asenapine The therapeutic efficacy of Glyburide can be decreased when used in combination with Asenapine.
Pitavastatin	Pitavastatin Glyburide may decrease the excretion rate of Pitavastatin which could result in a higher serum level.
Albendazole	Albendazole The metabolism of Glyburide can be decreased when combined with Albendazole.
Ulipristal	Ulipristal The therapeutic efficacy of Ulipristal can be decreased when used in combination with Glyburide.
Levonorgestrel	Levonorgestrel The therapeutic efficacy of Glyburide can be decreased when used in combination with Levonorgestrel.
Liraglutide Injection	Liraglutide Injection Liraglutide may increase the hypoglycemic activities of Glyburide.
Tocilizumab Injection	Tocilizumab Injection The metabolism of Glyburide can be increased when combined with Tocilizumab.
Cabazitaxel Injection	Cabazitaxel Injection The metabolism of Glyburide can be decreased when combined with Cabazitaxel.
Lurasidone	Lurasidone The therapeutic efficacy of Glyburide can be decreased when used in combination with Lurasidone.
Vilazodone	Vilazodone The metabolism of Vilazodone can be decreased when combined with Glyburide.
Terbutaline Injection	Terbutaline Injection The therapeutic efficacy of Glyburide can be decreased when used in combination with Terbutaline.
Busulfan Injection	Busulfan Injection The metabolism of Busulfan can be decreased when combined with Glyburide.
Roflumilast	Roflumilast The metabolism of Roflumilast can be decreased when combined with Glyburide.
Linagliptin	Linagliptin The risk or severity of hypoglycemia can be increased when Glyburide is combined with Linagliptin.
Rilpivirine	Rilpivirine Rilpivirine may decrease the excretion rate of Glyburide which could result in a higher serum level.
Telaprevir	Telaprevir Glecaprevir may decrease the excretion rate of Glyburide which could result in a higher serum level.
Potassium Iodide	Potassium Iodide The therapeutic efficacy of Glyburide can be decreased when used in combination with Potassium Iodide.
Cyclophosphamide Injection	Cyclophosphamide Injection The metabolism of Cyclophosphamide can be decreased when combined with Glyburide.
Abiraterone	Abiraterone The metabolism of Glyburide can be decreased when combined with Abiraterone.
Triptorelin Injection	Triptorelin Injection The therapeutic efficacy of Glyburide can be decreased when used in combination with Triptorelin.
Rivaroxaban	Rivaroxaban The metabolism of Rivaroxaban can be decreased when combined with Glyburide.
Ticagrelor	Ticagrelor The metabolism of Glyburide can be decreased when combined with Ticagrelor.
Brentuximab Vedotin Injection	Brentuximab Vedotin Injection The metabolism of Brentuximab vedotin can be decreased when combined with Glyburide.
Ruxolitinib	Ruxolitinib The metabolism of Ruxolitinib can be decreased when combined with Glyburide.
Vandetanib	Vandetanib The metabolism of Glyburide can be decreased when combined with Vandetanib.
Clobazam	Clobazam The metabolism of Glyburide can be decreased when combined with Clobazam.
Vemurafenib	Vemurafenib The metabolism of Glyburide can be decreased when combined with Vemurafenib.
Vismodegib	Vismodegib Vismodegib may decrease the excretion rate of Glyburide which could result in a higher serum level.
Ivacaftor	Ivacaftor The metabolism of Ivacaftor can be decreased when combined with Glyburide.
Axitinib	Axitinib The metabolism of Axitinib can be decreased when combined with Glyburide.
Crizotinib	Crizotinib The metabolism of Glyburide can be decreased when combined with Crizotinib.
Cabergoline	Cabergoline The metabolism of Cabergoline can be decreased when combined with Glyburide.
Ambrisentan	Ambrisentan The metabolism of Ambrisentan can be decreased when combined with Glyburide.
Enzalutamide	Enzalutamide The metabolism of Enzalutamide can be decreased when combined with Glyburide.
Regorafenib	Regorafenib The metabolism of Glyburide can be decreased when combined with Regorafenib.
Bosutinib	Bosutinib The metabolism of Bosutinib can be decreased when combined with Glyburide.
Corticotropin, Repository Injection	Corticotropin, Repository Injection The risk or severity of hyperglycemia can be increased when Corticotropin is combined with Glyburide.
Teriflunomide	Teriflunomide Teriflunomide may decrease the excretion rate of Glyburide which could result in a higher serum level.
Lorcaserin	Lorcaserin The risk or severity of hypoglycemia can be increased when Glyburide is combined with Mecasermin.
Cabozantinib (thyroid cancer)	Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be decreased when combined with Glyburide.
Tofacitinib	Tofacitinib The metabolism of Tofacitinib can be decreased when combined with Glyburide.
Alogliptin	Alogliptin Alogliptin may increase the hypoglycemic activities of Glyburide.
Ponatinib	Ponatinib The metabolism of Glyburide can be decreased when combined with Ponatinib.
Pomalidomide	Pomalidomide The metabolism of Pomalidomide can be decreased when combined with Glyburide.
Ado-trastuzumab Emtansine Injection	Ado-trastuzumab Emtansine Injection The metabolism of Trastuzumab emtansine can be decreased when combined with Glyburide.
Apixaban	Apixaban The metabolism of Apixaban can be decreased when combined with Glyburide.
Canagliflozin	Canagliflozin Canagliflozin may increase the hypoglycemic activities of Glyburide.
Methazolamide	Methazolamide The therapeutic efficacy of Glyburide can be increased when used in combination with Methazolamide.
Dabrafenib	Dabrafenib The serum concentration of Glyburide can be decreased when it is combined with Dabrafenib.
Ospemifene	Ospemifene The metabolism of Ospemifene can be decreased when combined with Glyburide.
Afatinib	Afatinib Afatinib may decrease the excretion rate of Glyburide which could result in a higher serum level.
Levomilnacipran	Levomilnacipran The risk or severity of hypoglycemia can be increased when Levomilnacipran is combined with Glyburide.
Vortioxetine	Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Glyburide.
Perampanel	Perampanel The metabolism of Perampanel can be decreased when combined with Glyburide.
Ibrutinib	Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Glyburide.
Lomitapide	Lomitapide The metabolism of Lomitapide can be decreased when combined with Glyburide.
Ketorolac Injection	Ketorolac Injection The protein binding of Glyburide can be decreased when combined with Ketorolac.
Simeprevir	Simeprevir The risk or severity of liver damage can be increased when Glyburide is combined with Simeprevir.
Dapagliflozin	Dapagliflozin The metabolism of Dapagliflozin can be decreased when combined with Glyburide.
Apremilast	Apremilast The metabolism of Glyburide can be increased when combined with Apremilast.
Ceritinib	Ceritinib The metabolism of Glyburide can be decreased when combined with Ceritinib.
Siltuximab Injection	Siltuximab Injection The metabolism of Glyburide can be increased when combined with Siltuximab.
Albiglutide Injection	Albiglutide Injection Albiglutide may increase the hypoglycemic activities of Glyburide.
Eslicarbazepine	Eslicarbazepine The metabolism of Glyburide can be decreased when combined with Eslicarbazepine.
Idelalisib	Idelalisib The metabolism of Idelalisib can be decreased when combined with Glyburide.
Testosterone Injection	Testosterone Injection The metabolism of Testosterone can be decreased when combined with Glyburide.
Oritavancin Injection	Oritavancin Injection The metabolism of Glyburide can be decreased when combined with Oritavancin.
Empagliflozin	Empagliflozin The risk or severity of hypoglycemia can be increased when Glyburide is combined with Empagliflozin.
Vorapaxar	Vorapaxar The metabolism of Vorapaxar can be decreased when combined with Glyburide.
Suvorexant	Suvorexant The metabolism of Suvorexant can be decreased when combined with Glyburide.
Dulaglutide Injection	Dulaglutide Injection Dulaglutide may increase the hypoglycemic activities of Glyburide.
Olaparib	Olaparib The metabolism of Glyburide can be decreased when combined with Olaparib.
Methamphetamine	Methamphetamine The therapeutic efficacy of Glyburide can be decreased when used in combination with Metamfetamine.
Tasimelteon	Tasimelteon The metabolism of Tasimelteon can be decreased when combined with Glyburide.
Lanreotide Injection	Lanreotide Injection The therapeutic efficacy of Glyburide can be decreased when used in combination with Lanreotide.
Nintedanib	Nintedanib The metabolism of Nintedanib can be decreased when combined with Glyburide.
Secukinumab Injection	Secukinumab Injection The metabolism of Glyburide can be increased when combined with Secukinumab.
Risperidone Injection	Risperidone Injection The therapeutic efficacy of Glyburide can be decreased when used in combination with Risperidone.
Palbociclib	Palbociclib The metabolism of Glyburide can be decreased when combined with Palbociclib.
Insulin Human Inhalation	Insulin Human Inhalation The risk or severity of hypoglycemia can be increased when Insulin human is combined with Glyburide.
Lenvatinib	Lenvatinib The risk or severity of liver damage can be increased when Glyburide is combined with Lenvatinib.
Naloxegol	Naloxegol The metabolism of Glyburide can be decreased when combined with Naloxegol.
Panobinostat	Panobinostat The metabolism of Panobinostat can be decreased when combined with Glyburide.
Haloperidol Injection	Haloperidol Injection The serum concentration of Haloperidol can be increased when it is combined with Glyburide.
Deoxycholic Acid Injection	Deoxycholic Acid Injection Deoxycholic acid may increase the excretion rate of Glyburide which could result in a lower serum level and potentially a reduction in efficacy.
Sonidegib	Sonidegib The metabolism of Sonidegib can be decreased when combined with Glyburide.
Rolapitant	Rolapitant Rolapitant may decrease the excretion rate of Glyburide which could result in a higher serum level.
Prednisolone	Prednisolone The risk or severity of hyperglycemia can be increased when Glyburide is combined with Prednisolone.
Daclatasvir	Daclatasvir Daclatasvir may decrease the excretion rate of Glyburide which could result in a higher serum level.
Brexpiprazole	Brexpiprazole The therapeutic efficacy of Glyburide can be decreased when used in combination with Brexpiprazole.
Ziprasidone Injection	Ziprasidone Injection The therapeutic efficacy of Glyburide can be decreased when used in combination with Ziprasidone.
Insulin Degludec (rDNA Origin) Injection	Insulin Degludec (rDNA Origin) Injection The risk or severity of hypoglycemia can be increased when Glyburide is combined with Insulin degludec.
Cobimetinib	Cobimetinib The metabolism of Cobimetinib can be decreased when combined with Glyburide.
Trabectedin Injection	Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Glyburide.
Osimertinib	Osimertinib The metabolism of Osimertinib can be decreased when combined with Glyburide.
Alectinib	Alectinib The metabolism of Glyburide can be decreased when combined with Alectinib.
Ixazomib	Ixazomib The metabolism of Ixazomib can be decreased when combined with Glyburide.
Rifapentine	Rifapentine The metabolism of Glyburide can be increased when combined with Rifapentine.
Lesinurad	Lesinurad The metabolism of Lesinurad can be decreased when combined with Glyburide.
Dexamethasone Injection	Dexamethasone Injection The risk or severity of hyperglycemia can be increased when Glyburide is combined with Dexamethasone.
Brivaracetam Injection	Brivaracetam Injection The metabolism of Brivaracetam can be decreased when combined with Glyburide.
Venetoclax	Venetoclax The metabolism of Glyburide can be decreased when combined with Venetoclax.
Cobicistat	Cobicistat The metabolism of Glyburide can be decreased when combined with Cobicistat.
Midodrine	Midodrine The therapeutic efficacy of Glyburide can be decreased when used in combination with Midodrine.
Obeticholic Acid	Obeticholic Acid The risk or severity of adverse effects can be increased when Glyburide is combined with Obeticholic acid.
Diphenhydramine Injection	Diphenhydramine Injection The metabolism of Diphenhydramine can be decreased when combined with Glyburide.
Furosemide Injection	Furosemide Injection The therapeutic efficacy of Glyburide can be increased when used in combination with Furosemide.
Rucaparib	Rucaparib Rucaparib may decrease the excretion rate of Glyburide which could result in a higher serum level.
Lixisenatide Injection	Lixisenatide Injection Lixisenatide may increase the hypoglycemic activities of Glyburide.
Ribociclib	Ribociclib The metabolism of Ribociclib can be decreased when combined with Glyburide.
Parathyroid Hormone Injection	Parathyroid Hormone Injection The therapeutic efficacy of Glyburide can be decreased when used in combination with Parathyroid hormone.
Brigatinib	Brigatinib The metabolism of Glyburide can be decreased when combined with Brigatinib.
Doxepin (Insomnia)	Doxepin (Insomnia) The metabolism of Doxepin can be decreased when combined with Glyburide.
Deutetrabenazine	Deutetrabenazine The metabolism of Deutetrabenazine can be decreased when combined with Glyburide.
Valbenazine	Valbenazine The metabolism of Valbenazine can be decreased when combined with Glyburide.
Deflazacort	Deflazacort The risk or severity of hyperglycemia can be increased when Deflazacort is combined with Glyburide.
Safinamide	Safinamide Safinamide may decrease the excretion rate of Glyburide which could result in a higher serum level.
Edaravone Injection	Edaravone Injection The excretion of Edaravone can be decreased when combined with Glyburide.
Midostaurin	Midostaurin The metabolism of Glyburide can be decreased when combined with Midostaurin.
Neratinib	Neratinib The metabolism of Neratinib can be decreased when combined with Glyburide.
Abaloparatide Injection	Abaloparatide Injection The therapeutic efficacy of Glyburide can be decreased when used in combination with Abaloparatide.
Enasidenib	Enasidenib The metabolism of Glyburide can be decreased when combined with Enasidenib.
Aprepitant/Fosaprepitant Injection	Aprepitant/Fosaprepitant Injection The metabolism of Fosaprepitant can be decreased when combined with Glyburide.
Copanlisib Injection	Copanlisib Injection The metabolism of Copanlisib can be decreased when combined with Glyburide.
Delafloxacin	Delafloxacin The therapeutic efficacy of Glyburide can be increased when used in combination with Delafloxacin.
Abemaciclib	Abemaciclib The metabolism of Glyburide can be decreased when combined with Abemaciclib.
Acalabrutinib	Acalabrutinib The metabolism of Glyburide can be decreased when combined with Acalabrutinib.
Letermovir	Letermovir The risk or severity of liver damage can be increased when Glyburide is combined with Letermovir.
Semaglutide Injection	Semaglutide Injection Semaglutide may increase the hypoglycemic activities of Glyburide.
Ertugliflozin	Ertugliflozin The therapeutic efficacy of Glyburide can be increased when used in combination with Ertugliflozin.
Buprenorphine Injection	Buprenorphine Injection Buprenorphine may decrease the excretion rate of Glyburide which could result in a higher serum level.
Apalutamide	Apalutamide The serum concentration of Glyburide can be increased when it is combined with Apalutamide.
Fostamatinib	Fostamatinib Fostamatinib may decrease the excretion rate of Glyburide which could result in a higher serum level.
Avatrombopag	Avatrombopag Avatrombopag may decrease the excretion rate of Glyburide which could result in a higher serum level.
Baricitinib	Baricitinib The metabolism of Glyburide can be decreased when combined with Baricitinib.
Eliglustat	Eliglustat The metabolism of Eliglustat can be decreased when combined with Glyburide.
Ivosidenib	Ivosidenib The metabolism of Ivosidenib can be decreased when combined with Glyburide.
Doravirine	Doravirine The metabolism of Doravirine can be decreased when combined with Glyburide.
Cannabidiol	Cannabidiol Cannabidiol may decrease the excretion rate of Glyburide which could result in a higher serum level.
Dacomitinib	Dacomitinib The metabolism of Glyburide can be decreased when combined with Dacomitinib.
Duvelisib	Duvelisib The metabolism of Duvelisib can be decreased when combined with Glyburide.
Stiripentol	Stiripentol The metabolism of Glyburide can be decreased when combined with Stiripentol.
Gilteritinib	Gilteritinib Gilteritinib may decrease the excretion rate of Glyburide which could result in a higher serum level.
Glasdegib	Glasdegib Glasdegib may decrease the excretion rate of Glyburide which could result in a higher serum level.
Lorlatinib	Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Glyburide.
Paclitaxel (with albumin) Injection	Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be decreased when combined with Glyburide.
Rifamycin	Rifamycin The metabolism of Rifamycin can be increased when combined with Glyburide.
Prucalopride	Prucalopride The metabolism of Prucalopride can be decreased when combined with Glyburide.
Emapalumab-lzsg Injection	Emapalumab-lzsg Injection The metabolism of Glyburide can be increased when combined with Emapalumab.
Siponimod	Siponimod The metabolism of Siponimod can be decreased when combined with Glyburide.
Acyclovir Ophthalmic	Acyclovir Ophthalmic The excretion of Acyclovir can be decreased when combined with Glyburide.
Erdafitinib	Erdafitinib The metabolism of Erdafitinib can be decreased when combined with Glyburide.
Esomeprazole Injection	Esomeprazole Injection The metabolism of Glyburide can be decreased when combined with Esomeprazole.
Alpelisib	Alpelisib The serum concentration of Glyburide can be decreased when it is combined with Alpelisib.
Darolutamide	Darolutamide The serum concentration of Glyburide can be increased when it is combined with Darolutamide.
Triclabendazole	Triclabendazole The metabolism of Triclabendazole can be decreased when combined with Glyburide.
Entrectinib	Entrectinib The metabolism of Entrectinib can be decreased when combined with Glyburide.
Pexidartinib	Pexidartinib The metabolism of Pexidartinib can be decreased when combined with Glyburide.
Istradefylline	Istradefylline The metabolism of Istradefylline can be decreased when combined with Glyburide.
Pitolisant	Pitolisant The serum concentration of Glyburide can be decreased when it is combined with Pitolisant.
Fedratinib	Fedratinib Fedratinib may decrease the excretion rate of Glyburide which could result in a higher serum level.
Lefamulin	Lefamulin The metabolism of Lefamulin can be decreased when combined with Glyburide.
Phenytoin Injection	Phenytoin Injection The therapeutic efficacy of Glyburide can be decreased when used in combination with Phenytoin.
Fosphenytoin Injection	Fosphenytoin Injection The therapeutic efficacy of Fosphenytoin can be decreased when used in combination with Glyburide.
Zanubrutinib	Zanubrutinib The metabolism of Zanubrutinib can be decreased when combined with Glyburide.
Voxelotor	Voxelotor The serum concentration of Voxelotor can be increased when it is combined with Glyburide.
Avapritinib	Avapritinib The metabolism of Avapritinib can be decreased when combined with Glyburide.
Lasmiditan	Lasmiditan The serum concentration of Glyburide can be increased when it is combined with Lasmiditan.
Ubrogepant	Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Glyburide.
Tazemetostat	Tazemetostat The metabolism of Tazemetostat can be decreased when combined with Glyburide.
Cenobamate	Cenobamate The serum concentration of Glyburide can be decreased when it is combined with Cenobamate.
Teprotumumab-trbw Injection	Teprotumumab-trbw Injection The therapeutic efficacy of Glyburide can be decreased when used in combination with Teprotumumab.
Selumetinib	Selumetinib The metabolism of Selumetinib can be decreased when combined with Glyburide.
Tucatinib	Tucatinib The metabolism of Tucatinib can be decreased when combined with Glyburide.
Ripretinib	Ripretinib Ripretinib may decrease the excretion rate of Glyburide which could result in a higher serum level.
Capmatinib	Capmatinib The serum concentration of Glyburide can be increased when it is combined with Capmatinib.
Lemborexant	Lemborexant The metabolism of Lemborexant can be decreased when combined with Glyburide.
Fostemsavir	Fostemsavir Fostemsavir may decrease the excretion rate of Glyburide which could result in a higher serum level.
Octreotide	Octreotide The therapeutic efficacy of Glyburide can be decreased when used in combination with Octreotide.
Belantamab Mafodotin-blmf Injection	Belantamab Mafodotin-blmf Injection Glyburide may decrease the excretion rate of Belantamab mafodotin which could result in a higher serum level.
Pralsetinib	Pralsetinib Pralsetinib may decrease the excretion rate of Glyburide which could result in a higher serum level.
Satralizumab-mwge Injection	Satralizumab-mwge Injection The serum concentration of Glyburide can be decreased when it is combined with Satralizumab.
Progestin-Only (drospirenone) Oral Contraceptives	Progestin-Only (drospirenone) Oral Contraceptives The therapeutic efficacy of Glyburide can be decreased when used in combination with Drospirenone.
Theophylline	Theophylline The metabolism of Theophylline can be decreased when combined with Glyburide.
Fenoprofen	Fenoprofen The protein binding of Glyburide can be decreased when combined with Fenoprofen.
Indomethacin	Indomethacin Glyburide may decrease the excretion rate of Indomethacin which could result in a higher serum level.
Mefenamic Acid	Mefenamic Acid The protein binding of Glyburide can be decreased when combined with Mefenamic acid.
Naproxen	Naproxen Glyburide may decrease the excretion rate of Naproxen which could result in a higher serum level.
Tolmetin	Tolmetin The protein binding of Glyburide can be decreased when combined with Tolmetin.
Sulindac	Sulindac The protein binding of Glyburide can be decreased when combined with Sulindac.
Trazodone	Trazodone The metabolism of Glyburide can be decreased when combined with Trazodone.
Floxuridine	Floxuridine The metabolism of Glyburide can be decreased when combined with Floxuridine.
Phenobarbital	Phenobarbital The metabolism of Phenobarbital can be decreased when combined with Glyburide.
Methotrexate Injection	Methotrexate Injection The metabolism of Methotrexate can be decreased when combined with Glyburide.
Primidone	Primidone The metabolism of Primidone can be decreased when combined with Glyburide.
Methsuximide	Methsuximide The metabolism of Glyburide can be decreased when combined with Methsuximide.
Diethylpropion	Diethylpropion The therapeutic efficacy of Glyburide can be decreased when used in combination with Diethylpropion.
Chlorpromazine	Chlorpromazine The therapeutic efficacy of Glyburide can be decreased when used in combination with Chlorpromazine.
Diazepam	Diazepam The metabolism of Diazepam can be decreased when combined with Glyburide.
Lorazepam	Lorazepam The metabolism of Glyburide can be decreased when combined with Lorazepam.
Bromocriptine	Bromocriptine The risk or severity of hypoglycemia can be increased when Glyburide is combined with Bromocriptine.
Metaproterenol	Metaproterenol The therapeutic efficacy of Glyburide can be decreased when used in combination with Orciprenaline.
Tranylcypromine	Tranylcypromine The metabolism of Glyburide can be decreased when combined with Tranylcypromine.
Phenelzine	Phenelzine The metabolism of Glyburide can be decreased when combined with Phenelzine.
Procarbazine	Procarbazine Procarbazine may increase the hypoglycemic activities of Glyburide.
Prochlorperazine	Prochlorperazine The therapeutic efficacy of Glyburide can be decreased when used in combination with Prochlorperazine.
Thioridazine	Thioridazine The therapeutic efficacy of Glyburide can be decreased when used in combination with Thioridazine.
Trifluoperazine	Trifluoperazine The therapeutic efficacy of Trifluoperazine can be decreased when used in combination with Glyburide.
Dapsone	Dapsone The metabolism of Dapsone can be decreased when combined with Glyburide.
Sulfadiazine	Sulfadiazine The therapeutic efficacy of Glyburide can be increased when used in combination with Sulfadiazine.
Oxycodone	Oxycodone The metabolism of Glyburide can be decreased when combined with Oxycodone.
Methadone	Methadone The metabolism of Methadone can be decreased when combined with Glyburide.
Oxybutynin	Oxybutynin The metabolism of Oxybutynin can be decreased when combined with Glyburide.
Ibuprofen	Ibuprofen The metabolism of Ibuprofen can be decreased when combined with Glyburide.
Perphenazine	Perphenazine The therapeutic efficacy of Glyburide can be decreased when used in combination with Perphenazine.
Fluphenazine	Fluphenazine The therapeutic efficacy of Glyburide can be decreased when used in combination with Fluphenazine.
Phentermine	Phentermine The therapeutic efficacy of Glyburide can be increased when used in combination with Phentermine.
Amoxapine	Amoxapine Amoxapine may decrease the hypoglycemic activities of Glyburide.
Sulfasalazine	Sulfasalazine Sulfasalazine may increase the hypoglycemic activities of Glyburide.
Hydrocortisone	Hydrocortisone The risk or severity of hyperglycemia can be increased when Hydrocortisone is combined with Glyburide.
Doxorubicin	Doxorubicin The metabolism of Doxorubicin can be decreased when combined with Glyburide.
Carbamazepine	Carbamazepine The metabolism of Carbamazepine can be decreased when combined with Glyburide.
Clonidine	Clonidine The metabolism of Glyburide can be decreased when combined with Clonidine.
Cimetidine	Cimetidine The serum concentration of Glyburide can be increased when it is combined with Cimetidine.
Warfarin	Warfarin The serum concentration of Warfarin can be increased when it is combined with Glyburide.
Loperamide	Loperamide The risk or severity of hypoglycemia can be increased when Loperamide is combined with Glyburide.
Promethazine	Promethazine The therapeutic efficacy of Glyburide can be decreased when used in combination with Promethazine.
Meclofenamate	Meclofenamate The protein binding of Glyburide can be decreased when combined with Meclofenamic acid.
Daunorubicin	Daunorubicin Glyburide may decrease the excretion rate of Daunorubicin which could result in a higher serum level.
Nitrofurantoin	Nitrofurantoin Glyburide may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level.
Digoxin	Digoxin Glyburide may decrease the excretion rate of Digoxin which could result in a higher serum level.
Chloroquine	Chloroquine The metabolism of Glyburide can be decreased when combined with Chloroquine.
Quinine	Quinine The metabolism of Quinine can be decreased when combined with Glyburide.
Ethosuximide	Ethosuximide The risk or severity of hypoglycemia can be increased when Ethosuximide is combined with Glyburide.
Sulfinpyrazone	Sulfinpyrazone Glyburide may decrease the excretion rate of Sulfinpyrazone which could result in a higher serum level.
Chlorothiazide	Chlorothiazide The therapeutic efficacy of Glyburide can be decreased when used in combination with Chlorothiazide.
Chlorthalidone	Chlorthalidone The therapeutic efficacy of Glyburide can be decreased when used in combination with Chlorthalidone.
Metolazone	Metolazone The therapeutic efficacy of Glyburide can be decreased when used in combination with Metolazone.
Isosorbide	Isosorbide The therapeutic efficacy of Glyburide can be decreased when used in combination with Isosorbide.
Clindamycin Injection	Clindamycin Injection The metabolism of Clindamycin can be decreased when combined with Glyburide.
Desipramine	Desipramine Desipramine may decrease the hypoglycemic activities of Glyburide.
Amitriptyline	Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Glyburide.
Imipramine	Imipramine The metabolism of Glyburide can be decreased when combined with Imipramine.
Probenecid	Probenecid The protein binding of Glyburide can be decreased when combined with Probenecid.
Quinidine	Quinidine The metabolism of Quinidine can be decreased when combined with Glyburide.
Isoniazid	Isoniazid The therapeutic efficacy of Glyburide can be decreased when used in combination with Isoniazid.
Rifampin	Rifampin The serum concentration of Glyburide can be decreased when it is combined with Rifampicin.
Disopyramide	Disopyramide The risk or severity of hypoglycemia can be increased when Disopyramide is combined with Glyburide.
Valproic Acid	Valproic Acid The metabolism of Glyburide can be decreased when combined with Valproic acid.
Tamoxifen	Tamoxifen The metabolism of Glyburide can be decreased when combined with Tamoxifen.
Levothyroxine	Levothyroxine The therapeutic efficacy of Levothyroxine can be decreased when used in combination with Glyburide.
Liothyronine	Liothyronine The therapeutic efficacy of Glyburide can be decreased when used in combination with Liothyronine.
Methimazole	Methimazole The therapeutic efficacy of Glyburide can be decreased when used in combination with Methimazole.
Propylthiouracil	Propylthiouracil The therapeutic efficacy of Glyburide can be decreased when used in combination with Propylthiouracil.
Chlorpropamide	Chlorpropamide The metabolism of Chlorpropamide can be decreased when combined with Glyburide.
Tolbutamide	Tolbutamide The metabolism of Tolbutamide can be decreased when combined with Glyburide.
Tolazamide	Tolazamide The metabolism of Tolazamide can be decreased when combined with Glyburide.
Dextromethorphan	Dextromethorphan The metabolism of Dextromethorphan can be decreased when combined with Glyburide.
Dinoprostone	Dinoprostone The excretion of Dinoprostone can be decreased when combined with Glyburide.
Niacin	Niacin The therapeutic efficacy of Glyburide can be decreased when used in combination with Niacin.
Baclofen	Baclofen The therapeutic efficacy of Glyburide can be decreased when used in combination with Baclofen.
Chlorpheniramine	Chlorpheniramine The metabolism of Chlorpheniramine can be decreased when combined with Glyburide.
Methyclothiazide	Methyclothiazide The therapeutic efficacy of Glyburide can be decreased when used in combination with Methyclothiazide.
Hydrochlorothiazide	Hydrochlorothiazide The therapeutic efficacy of Glyburide can be decreased when used in combination with Hydrochlorothiazide.
Carisoprodol	Carisoprodol The metabolism of Glyburide can be decreased when combined with Carisoprodol.
Danazol	Danazol The therapeutic efficacy of Glyburide can be decreased when used in combination with Danazol.
Disulfiram	Disulfiram Glyburide may decrease the excretion rate of Disulfiram which could result in a higher serum level.
Propranolol (Cardiovascular)	Propranolol (Cardiovascular) The therapeutic efficacy of Glyburide can be increased when used in combination with Propranolol.
Pseudoephedrine	Pseudoephedrine The therapeutic efficacy of Glyburide can be decreased when used in combination with Pseudoephedrine.
Nortriptyline	Nortriptyline The metabolism of Glyburide can be decreased when combined with Nortriptyline.
Spironolactone	Spironolactone Glyburide may decrease the excretion rate of Spironolactone which could result in a higher serum level.
Nadolol	Nadolol The therapeutic efficacy of Glyburide can be increased when used in combination with Nadolol.
Fluoxymesterone	Fluoxymesterone Fluoxymesterone may increase the hypoglycemic activities of Glyburide.
Fluorouracil Injection	Fluorouracil Injection The metabolism of Glyburide can be decreased when combined with Fluorouracil.
Colchicine	Colchicine The metabolism of Colchicine can be decreased when combined with Glyburide.
Cefaclor	Cefaclor Glyburide may decrease the excretion rate of Cefaclor which could result in a higher serum level.
Cefazolin Injection	Cefazolin Injection The excretion of Cefazolin can be decreased when combined with Glyburide.
Cephalexin	Cephalexin The metabolism of Cephalexin can be decreased when combined with Glyburide.
Acetazolamide	Acetazolamide The therapeutic efficacy of Glyburide can be increased when used in combination with Acetazolamide.
Calcitonin Salmon Injection	Calcitonin Salmon Injection The therapeutic efficacy of Glyburide can be decreased when used in combination with Salmon calcitonin.
Ketoconazole	Ketoconazole The metabolism of Ketoconazole can be decreased when combined with Glyburide.
Thiotepa Injection	Thiotepa Injection The metabolism of Thiotepa can be decreased when combined with Glyburide.
Vincristine Injection	Vincristine Injection The metabolism of Glyburide can be decreased when combined with Vincristine.
Captopril	Captopril The excretion of Captopril can be decreased when combined with Glyburide.
Dipyridamole	Dipyridamole Glyburide may decrease the excretion rate of Dipyridamole which could result in a higher serum level.
Isoxsuprine	Isoxsuprine The therapeutic efficacy of Glyburide can be decreased when used in combination with Isoxsuprine.
Vinblastine	Vinblastine The metabolism of Glyburide can be decreased when combined with Vinblastine.
Ethacrynic Acid	Ethacrynic Acid The therapeutic efficacy of Glyburide can be decreased when used in combination with Etacrynic acid.
Metoprolol	Metoprolol The therapeutic efficacy of Glyburide can be increased when used in combination with Metoprolol.
Hydroxyzine	Hydroxyzine The metabolism of Glyburide can be decreased when combined with Hydroxyzine.
Aspirin	Aspirin The risk or severity of hypoglycemia can be increased when Acetylsalicylic acid is combined with Glyburide.
Salsalate	Salsalate The protein binding of Glyburide can be decreased when combined with Salsalate.
Alprazolam	Alprazolam The metabolism of Alprazolam can be decreased when combined with Glyburide.
Triazolam	Triazolam The metabolism of Glyburide can be decreased when combined with Triazolam.
Trimethoprim	Trimethoprim The metabolism of Trimethoprim can be decreased when combined with Glyburide.
Diltiazem	Diltiazem The metabolism of Diltiazem can be decreased when combined with Glyburide.
Nifedipine	Nifedipine Glyburide may decrease the excretion rate of Nifedipine which could result in a higher serum level.
Timolol	Timolol The therapeutic efficacy of Glyburide can be increased when used in combination with Timolol.
Verapamil	Verapamil The metabolism of Glyburide can be decreased when combined with Verapamil.
Atenolol	Atenolol The therapeutic efficacy of Atenolol can be increased when used in combination with Glyburide.
Pindolol	Pindolol The therapeutic efficacy of Glyburide can be increased when used in combination with Pindolol.
Cisplatin Injection	Cisplatin Injection The metabolism of Glyburide can be decreased when combined with Cisplatin.
Diflunisal	Diflunisal Diflunisal may increase the hypoglycemic activities of Glyburide.
Piroxicam	Piroxicam The protein binding of Glyburide can be decreased when combined with Piroxicam.
Bumetanide	Bumetanide The therapeutic efficacy of Glyburide can be increased when used in combination with Bumetanide.
Etoposide	Etoposide The metabolism of Glyburide can be decreased when combined with Etoposide.
Glipizide	Glipizide Glyburide may decrease the excretion rate of Glipizide which could result in a higher serum level.
Indapamide	Indapamide The therapeutic efficacy of Glyburide can be decreased when used in combination with Indapamide.
Pentamidine Injection	Pentamidine Injection The therapeutic efficacy of Glyburide can be decreased when used in combination with Pentamidine.
Labetalol	Labetalol The therapeutic efficacy of Glyburide can be decreased when used in combination with Labetalol.
Leuprolide Injection	Leuprolide Injection The therapeutic efficacy of Glyburide can be decreased when used in combination with Leuprolide.
Gemfibrozil	Gemfibrozil The metabolism of Glyburide can be decreased when combined with Gemfibrozil.
Dipivefrin Ophthalmic	Dipivefrin Ophthalmic The excretion of Adefovir dipivoxil can be decreased when combined with Glyburide.
Ketoprofen	Ketoprofen The protein binding of Glyburide can be decreased when combined with Ketoprofen.
Pimozide	Pimozide The metabolism of Pimozide can be decreased when combined with Glyburide.
Flurbiprofen	Flurbiprofen The protein binding of Glyburide can be decreased when combined with Flurbiprofen.
Amiodarone	Amiodarone The metabolism of Amiodarone can be decreased when combined with Glyburide.
Buspirone	Buspirone The metabolism of Glyburide can be decreased when combined with Buspirone.
Lovastatin	Lovastatin The metabolism of Lovastatin can be decreased when combined with Glyburide.
Ciprofloxacin	Ciprofloxacin The therapeutic efficacy of Glyburide can be increased when used in combination with Ciprofloxacin.
Mesalamine	Mesalamine Mesalazine may increase the hypoglycemic activities of Glyburide.
Diclofenac	Diclofenac Glyburide may decrease the excretion rate of Diclofenac which could result in a higher serum level.
Fluoxetine	Fluoxetine The metabolism of Glyburide can be decreased when combined with Fluoxetine.
Nimodipine	Nimodipine The risk or severity of hypoglycemia can be increased when Nimodipine is combined with Glyburide.
Clozapine	Clozapine The therapeutic efficacy of Glyburide can be decreased when used in combination with Clozapine.
Idarubicin	Idarubicin The metabolism of Idarubicin can be decreased when combined with Glyburide.
Ofloxacin	Ofloxacin Glyburide may decrease the excretion rate of Ofloxacin which could result in a higher serum level.
Didanosine	Didanosine The excretion of Didanosine can be decreased when combined with Glyburide.
Clarithromycin	Clarithromycin The serum concentration of Glyburide can be increased when it is combined with Clarithromycin.
Benazepril	Benazepril The risk or severity of hypoglycemia can be increased when Benazepril is combined with Glyburide.
Etodolac	Etodolac The protein binding of Glyburide can be decreased when combined with Etodolac.
Felodipine	Felodipine The metabolism of Felodipine can be decreased when combined with Glyburide.
Nabumetone	Nabumetone The protein binding of Glyburide can be decreased when combined with Nabumetone.
Pravastatin	Pravastatin Glyburide may decrease the excretion rate of Pravastatin which could result in a higher serum level.
Simvastatin	Simvastatin The metabolism of Glyburide can be decreased when combined with Simvastatin.
Amlodipine	Amlodipine The risk or severity of hypoglycemia can be increased when Amlodipine is combined with Glyburide.
Teniposide Injection	Teniposide Injection The metabolism of Glyburide can be decreased when combined with Teniposide.
Itraconazole	Itraconazole The metabolism of Itraconazole can be decreased when combined with Glyburide.
Oxaprozin	Oxaprozin The protein binding of Glyburide can be decreased when combined with Oxaprozin.
Atovaquone	Atovaquone The metabolism of Glyburide can be decreased when combined with Atovaquone.
Rifabutin	Rifabutin The metabolism of Glyburide can be increased when combined with Rifabutin.
Sotalol	Sotalol The risk or severity of hypoglycemia can be increased when Sotalol is combined with Glyburide.
Bisoprolol	Bisoprolol The therapeutic efficacy of Glyburide can be increased when used in combination with Bisoprolol.
Zolpidem	Zolpidem The metabolism of Glyburide can be decreased when combined with Zolpidem.
Doxazosin	Doxazosin The metabolism of Doxazosin can be decreased when combined with Glyburide.
Isradipine	Isradipine Glyburide may decrease the excretion rate of Isradipine which could result in a higher serum level.
Omeprazole	Omeprazole Omeprazole may decrease the excretion rate of Glyburide which could result in a higher serum level.
Cisapride	Cisapride The metabolism of Cisapride can be decreased when combined with Glyburide.
Fluvastatin	Fluvastatin The metabolism of Fluvastatin can be decreased when combined with Glyburide.
Venlafaxine	Venlafaxine The metabolism of Glyburide can be decreased when combined with Venlafaxine.
Stavudine	Stavudine The excretion of Stavudine can be decreased when combined with Glyburide.
Famciclovir	Famciclovir The metabolism of Glyburide can be decreased when combined with Famciclovir.
Fluvoxamine	Fluvoxamine The metabolism of Fluvoxamine can be decreased when combined with Glyburide.
Nefazodone	Nefazodone The risk or severity of hypoglycemia can be increased when Glyburide is combined with Nefazodone.
Lamotrigine	Lamotrigine The risk or severity of hypoglycemia can be increased when Lamotrigine is combined with Glyburide.
Losartan	Losartan Glyburide may decrease the excretion rate of Losartan which could result in a higher serum level.
Tramadol	Tramadol The metabolism of Tramadol can be decreased when combined with Glyburide.
Vinorelbine Injection	Vinorelbine Injection The metabolism of Vinorelbine can be decreased when combined with Glyburide.
Lansoprazole	Lansoprazole The metabolism of Lansoprazole can be decreased when combined with Glyburide.
Alprostadil Urogenital	Alprostadil Urogenital The excretion of Alprostadil can be decreased when combined with Glyburide.
Ifosfamide Injection	Ifosfamide Injection The metabolism of Ifosfamide can be decreased when combined with Glyburide.
Nicardipine	Nicardipine The metabolism of Glyburide can be decreased when combined with Nicardipine.
Bupropion	Bupropion The metabolism of Bupropion can be decreased when combined with Glyburide.
Ticlopidine	Ticlopidine The metabolism of Glyburide can be decreased when combined with Ticlopidine.
Saquinavir	Saquinavir The metabolism of Glyburide can be decreased when combined with Saquinavir.
Nisoldipine	Nisoldipine The risk or severity of hypoglycemia can be increased when Nisoldipine is combined with Glyburide.
Lamivudine	Lamivudine The excretion of Lamivudine can be decreased when combined with Glyburide.
Acarbose	Acarbose The risk or severity of hypoglycemia can be increased when Acarbose is combined with Glyburide.
Glimepiride	Glimepiride Glyburide may decrease the excretion rate of Glimepiride which could result in a higher serum level.
Indinavir	Indinavir Indinavir may decrease the excretion rate of Glyburide which could result in a higher serum level.
Ritonavir	Ritonavir The serum concentration of Ritonavir can be increased when it is combined with Glyburide.
Docetaxel Injection	Docetaxel Injection The metabolism of Docetaxel can be decreased when combined with Glyburide.
Cidofovir Injection	Cidofovir Injection The excretion of Cidofovir can be decreased when combined with Glyburide.
Clomipramine	Clomipramine The metabolism of Glyburide can be decreased when combined with Clomipramine.
Zafirlukast	Zafirlukast The metabolism of Glyburide can be decreased when combined with Zafirlukast.
Topiramate	Topiramate The serum concentration of Topiramate can be decreased when it is combined with Glyburide.
Zileuton	Zileuton The metabolism of Zileuton can be decreased when combined with Glyburide.
Valsartan	Valsartan The metabolism of Glyburide can be decreased when combined with Valsartan.
Insulin Lispro Injection	Insulin Lispro Injection The risk or severity of hypoglycemia can be increased when Insulin lispro is combined with Glyburide.
Donepezil	Donepezil The metabolism of Donepezil can be decreased when combined with Glyburide.
Nelfinavir	Nelfinavir The metabolism of Nelfinavir can be decreased when combined with Glyburide.
Azithromycin	Azithromycin The metabolism of Azithromycin can be decreased when combined with Glyburide.
Loratadine	Loratadine Glyburide may decrease the excretion rate of Loratadine which could result in a higher serum level.
Carvedilol	Carvedilol The therapeutic efficacy of Glyburide can be increased when used in combination with Carvedilol.
Nilutamide	Nilutamide The metabolism of Glyburide can be decreased when combined with Nilutamide.
Flutamide	Flutamide The metabolism of Glyburide can be decreased when combined with Flutamide.
Selegiline	Selegiline The metabolism of Selegiline can be decreased when combined with Glyburide.
Bicalutamide	Bicalutamide The metabolism of Glyburide can be decreased when combined with Bicalutamide.
Sertraline	Sertraline The metabolism of Sertraline can be decreased when combined with Glyburide.
Propafenone	Propafenone The therapeutic efficacy of Glyburide can be increased when used in combination with Propafenone.
Letrozole	Letrozole The metabolism of Glyburide can be decreased when combined with Letrozole.
Irbesartan	Irbesartan The metabolism of Irbesartan can be decreased when combined with Glyburide.
Tamsulosin	Tamsulosin The therapeutic efficacy of Glyburide can be increased when used in combination with Tamsulosin.
Finasteride	Finasteride The metabolism of Finasteride can be decreased when combined with Glyburide.
Quetiapine	Quetiapine The therapeutic efficacy of Quetiapine can be decreased when used in combination with Glyburide.
Paroxetine	Paroxetine The metabolism of Glyburide can be decreased when combined with Paroxetine.
Tolcapone	Tolcapone The metabolism of Glyburide can be decreased when combined with Tolcapone.
Citalopram	Citalopram The metabolism of Glyburide can be decreased when combined with Citalopram.
Capecitabine	Capecitabine The metabolism of Glyburide can be decreased when combined with Capecitabine.
Efavirenz	Efavirenz The metabolism of Glyburide can be increased when combined with Efavirenz.
Sildenafil	Sildenafil The metabolism of Sildenafil can be decreased when combined with Glyburide.
Pioglitazone	Pioglitazone The therapeutic efficacy of Pioglitazone can be increased when used in combination with Glyburide.
Celecoxib	Celecoxib The risk or severity of liver damage can be increased when Celecoxib is combined with Glyburide.
Rosiglitazone	Rosiglitazone The therapeutic efficacy of Rosiglitazone can be increased when used in combination with Glyburide.
Tolterodine	Tolterodine The metabolism of Tolterodine can be decreased when combined with Glyburide.
Thalidomide	Thalidomide The metabolism of Thalidomide can be decreased when combined with Glyburide.
Colesevelam	Colesevelam The serum concentration of Glyburide can be decreased when it is combined with Colesevelam.
Balsalazide	Balsalazide Balsalazide may increase the hypoglycemic activities of Glyburide.
Nateglinide	Nateglinide The metabolism of Nateglinide can be decreased when combined with Glyburide.
Rabeprazole	Rabeprazole Rabeprazole may decrease the excretion rate of Glyburide which could result in a higher serum level.
Terbinafine	Terbinafine The metabolism of Terbinafine can be decreased when combined with Glyburide.