Parsley - Eminase (anistreplase, APSAC) Interaction
Herbal: Parsley
Also Known As: Petroselinum crispum, Common Parsley, Garden Parsley, Hamburg Parsley, Parsley Fruit, Parsley Oil, Parsley Seed, Perejil, Persely, Persil, Persil Cultivé, Persil Plat, Persin, Petersylinge, Petroselini Herba, Petrosilini Radix, Prajmoda, Racine de Persil, Rock Parsley
Drug: anistreplase, APSAC
Brand names:
Eminase
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jul 22, 2023
Interaction Details
anistreplase, APSAC is classified as belonging to the following category: Anticoagulant/Antiplatelet Drugs
Animal research suggests that parsley has antiplatelet effects. Theoretically, concomitant use of parsley with other anticoagulant/antiplatelet drugs might reduce platelet aggregation and increase the risk of bleeding.
Some anticoagulant/antiplatelet drugs include aspirin, clopidogrel (Plavix), ticagrelor (Brilinta) diclofenac (Voltaren, Cataflam), ibuprofen (Advil, Motrin), naproxen (Anaprox, Naprosyn), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Gadi, D., Bnouham, M., Aziz, M., Ziyyat, A., Legssyer, A., Legrand, C., Lafeve, F. F., and Mekhfi, H. Parsley extract inhibits in vitro and ex vivo platelet aggregation and prolongs bleeding time in rats. J Ethnopharmacol 8-17-2009;125(1):170-174.
Parsley Overview
Parsley is a herb that is native to the Mediterranean region and is widely cultivated for its leaves, which are used as a spice in cooking. In traditional medicine, parsley is believed to have a number of health benefits and is often used as a natural diuretic, increasing urine production. This property may make parsley useful in the treatment of certain conditions, such as bloating and water retention. It is also commonly used for gastrointestinal problems.
Parsley - More Interactions
Parsley interacts with 435 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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