Perilla - Nuvigil (Armodafinil) Interaction
Herbal: Perilla
Also Known As: Dentidia nankinensis, Ocimum frutescens, Perilla arguta, Perilla nankinensis, Perilla ocymoides, Beefsteak Plant, Huile de Pérille, Ja-So-Yeop, Japanese Basil, Japanese Melissea, Menthe Pourpre, Perilla Oil, Perilla Seed Oil, Pérille, Purple Mint, Purple Perilla, Shiso
Drug: Armodafinil
Brand names:
Nuvigil
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 26, 2024
Interaction Details
There were no interactions found between Armodafinil and Perilla. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Perilla Overview
Perilla frutescens, an annual plant native to Asia, is valued for its diverse applications in cooking, manufacturing, and traditional medicine. Its leaves, stem, and seeds are utilized in traditional Chinese medicine for their rich content of flavones like apigenin, luteolin, shishonin, and vicenin-2, as well as beneficial compounds such as alpha-linolenic acid, rosmarinic acid, and policosanol. These components are purported to contribute to a range of health benefits, including potential anti-allergy properties that may alleviate symptoms like atopic dermatitis and airway inflammation, possibly by reducing inflammatory mediators and mast cell activity. Its anti-inflammatory effects, which may involve inhibiting cytokine production and modulating immune cell activity, align with its traditional uses for allergies, asthma, and gastrointestinal issues. Moreover, perilla is said to exhibit antimicrobial effects, with its seed extract, oil, and essential oil showing potential activity against bacteria and fungi. Laboratory research suggests potential nephroprotective effects, indicating that perilla may inhibit the proliferation of mesangial cells in kidney disorders.
Armodafinil Overview
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Armodafinil is used to treat excessive sleepiness caused by narcolepsy (a condition that causes excessive daytime sleepiness) or shift work sleep disorder (sleepiness during scheduled waking hours and difficulty falling asleep or staying asleep during scheduled sleeping hours in people who work at night or on rotating shifts). Armodafinil is also used along with breathing devices or other treatments to prevent excessive sleepiness caused by obstructive sleep apnea/hypopnea syndrome (OSAHS; a sleep disorder in which the patient briefly stops breathing or breathes shallowly many times during sleep and therefore does not get enough restful sleep). Armodafinil is in a class of medications called wakefulness-promoting agents. It works by changing the amounts of certain natural substances in the area of the brain that controls sleep and wakefulness.
Perilla - More Interactions
Perilla interacts with 0 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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