Interaction Details

There were no interactions found between Riociguat and Stinging Nettle. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.


Still looking for more information about combining Riociguat and Stinging Nettle? Ask Dr. Brian Staiger about it by contacting him directly.

Stinging Nettle Overview

Stinging Nettle Stinging nettle (Urtica dioica) is a perennial flowering plant that belongs to the Urticaceae family. It is native to Europe, Asia, and North America, and is characterized by its green leaves and small, greenish-white flowers. Stinging nettle has small, stinging hairs on its leaves and stems, which can cause a painful rash when touched. The leaves and the roots of stinging nettle have been used in traditional medicine to treat a variety of conditions such as joint pain, diabetes, enlarged prostate, anemia, and urinary tract infections. It is also used as a diuretic and to help with allergies as it contains the compound quercetin. The leaves and stems of the plant are edible and can be consumed as a vegetable, usually after boiling or steaming to remove the stinging hairs, as the plant is rich in vitamins, minerals, and antioxidants.
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Riociguat Overview

  • Riociguat is used to treat pulmonary arterial hypertension (PAH; high blood pressure in the vessels that carry blood to the lungs). Riociguat is also used to treat chronic thromboembolic pulmonary hypertension (CTEPH; high blood pressure in the lung arteries caused by blood clots that narrow or block blood flow) in adults who cannot have surgery or for those treated with surgery who continue to have high lung blood pressure levels after surgery. Riociguat may improve the ability to exercise in people with PAH and CTEPH and may slow the worsening of symptoms in people with PAH. Riociguat is in a class of medications called soluble guanylate cyclase (sGC) stimulators. It works by relaxing the blood vessels in the lungs to allow blood to flow easily.

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Stinging Nettle - More Interactions

Stinging Nettle interacts with 162 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.

Major The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur.
Moderate Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur.
Minor Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction.
Unknown No interactions have been reported or no interaction data is currently available.

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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Drug descriptions are provided by MedlinePlus.

Ask A Pharmacist About Your Herbal Questions!

Dr. Brian Staiger, PharmD

In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!

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