Strontium - Helidac (Bismuth Subsalicylate, Metronidazole, Tetracycline) Interaction

Interaction Details

Bismuth Subsalicylate, Metronidazole, Tetracycline is classified as belonging to the following category: Tetracycline Antibiotics

Strontium is a divalent cation with similar properties to calcium. It is likely to form complexes with tetracyclines in the gastrointestinal (GI) tract, preventing absorption of the antibiotic. Recommend taking strontium supplements at least 2 hours before or after tetracyclines to avoid an interaction.
Tetracycline antibiotics include demeclocycline (Declomycin), doxycycline (Vibramycin), minocycline (Minocin), and tetracycline.

Interaction Rating

Likelihood of Occurrence

Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.

References

• Protelos European Summary of Product Characteristics. Les Laboratoires Servier, 2006. Available at: www.servier.com/pro/osteoporose/protelos/protelos_spc.asp. (Accessed 01 August 2006).

Bismuth Subsalicylate, Metronidazole, Tetracycline Overview

• Bismuth, metronidazole, and tetracycline is used along with other ulcer medications to treat duodenal ulcers. It is in a class of medications called antibacterial agents. It works by preventing the growth and spread of Helicobacter pylori bacteria, which often occurs with ulcers. Treating this infection keeps ulcers from coming back.

Strontium - More Interactions

Strontium interacts with 100 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.