Sweet Clover - Femara (Letrozole) Interaction
Herbal: Sweet Clover
Also Known As: Melilotus officinalis, Angipars, Casse Lunettes, Common Melilot, Couronne Royale, Field Melilot, Hart's Tree, Hay Flower, Herbe aux Puces, King's Clover, Luzerne Bâtarde, Melilot, Mélilot, Mélilot des Champs, Mélilot Commun, Mélilot Jaune, Mélilot Officinal
Drug: Letrozole
Brand names:
Femara
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Apr 13, 2024
Interaction Details
There were no interactions found between Letrozole and Sweet Clover. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Sweet Clover Overview
Sweet clover is a tall, herbaceous plant with yellow flowers that belongs to the pea family (Fabaceae). It is native to Europe and Asia, but has been introduced to many other parts of the world, including North America. There are two main species of sweet clover: Melilotus albus, which is white sweet clover, and Melilotus officinalis, which is yellow sweet clover. Sweet clover is purported to have a number of medicinal properties and has been used traditionally to treat a variety of ailments, such as respiratory problems and skin conditions. It has also been used as a phlebotonic (drug that modifies the tone of vein walls) and an antithrombotic.
Letrozole Overview
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Letrozole is used treat early breast cancer in women who have experienced menopause (change of life; end of monthly menstrual periods) and who have had other treatments, such as radiation or surgery to remove the tumor. It is also used to treat early breast cancer in women who have experienced menopause and who have already been treated with a medication called tamoxifen (Nolvadex) for 5 years. Letrozole is also used in women who have experienced menopause as a first treatment of breast cancer that has spread within the breast or to other areas of the body or in women whose breast cancer has worsened while they were taking tamoxifen. Letrozole is in a class of medications called nonsteroidal aromatase inhibitors. It works by decreasing the amount of estrogen produced by the body. This can slow or stop the growth of some types of breast cancer cells that need estrogen to grow.
Sweet Clover - More Interactions
Sweet Clover interacts with 449 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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