Vitamin B12 - Actemra (Tocilizumab) Interaction
Herbal: Vitamin B12
Also Known As: B-12, B12, B Complex, Bedumil, Cobalamin, Cobalamin Enzyme, Coenzyme B12, Co-Enzyme B12, Coenzyme B-12, Co-Enzyme B-12, Cycobemin, Dibencozide, Dibencozida, Hydroxycobalamine, Hydroxocobalaminum, Vitadurin, Vitadurine, Vitamina B12, methylcobalamin
Drug: Tocilizumab
Brand names:
Actemra
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 26, 2024
Interaction Details
There were no interactions found between Tocilizumab and Vitamin B12. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Vitamin B12 Overview
Vitamin B12, also known as cobalamin, is a water-soluble vitamin crucial for several bodily functions. It plays a pivotal role in the formation of red blood cells, aiding in the prevention of anemia. Vitamin B12 is essential for maintaining a healthy nervous system and proper brain function, as it is involved in the synthesis of myelin, the protective sheath around nerve fibers. This vitamin is primarily found in animal-based foods such as meat, fish, dairy products, and eggs, making it important for vegetarians and vegans to consider supplementation. A deficiency in vitamin B12 can lead to neurological issues, fatigue, and cognitive impairment.
Tocilizumab Overview
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Tocilizumab injection is used alone or in combination with other medications to relieve the symptoms of certain types of arthritis and other conditions including:
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rheumatoid arthritis (a condition in which the body attacks its own joints, causing pain, swelling, and loss of function) in adults who have not been helped by other disease-modifying antirheumatic drugs (DMARDs),
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giant cell arteritis (a condition that causes swelling of blood vessels, especially in the scalp and head) in adults,
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systemic sclerosis-associated interstitial lung disease (SSc-ILD; also known as scleroderma-associated ILD: a lung disease that involves scarring of the lungs) in adults,
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polyarticular juvenile idiopathic arthritis (PJIA; a type of childhood arthritis that affects five or more joints during the first six months of the condition, causing pain, swelling, and loss of function) in children 2 years of age or older.
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systemic juvenile idiopathic arthritis (SJIA; a condition in children that causes inflammation in different areas of the body, causing fever, joint pain and swelling, loss of function, and delays in growth and development) in children 2 years of age or older,
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cytokine release syndrome (a severe and possibly life-threatening reaction) in adults and children 2 years of age or older after receiving certain immunotherapy infusions.
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Tocilizumab injection is in a class of medications called interleukin-6 (IL-6) receptor inhibitors. It works by blocking the activity of interleukin-6, a substance in the body that causes inflammation.
Vitamin B12 - More Interactions
Vitamin B12 interacts with 19 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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