Tocilizumab Injection

Tocilizumab injection is used alone or in combination with other medications to relieve the symptoms of certain types of arthritis and other conditions including:

• rheumatoid arthritis (a condition in which the body attacks its own joints, causing pain, swelling, and loss of function) in adults who have not been helped by other disease-modifying antirheumatic drugs (DMARDs),

• giant cell arteritis (a condition that causes swelling of blood vessels, especially in the scalp and head) in adults,

• systemic sclerosis-associated interstitial lung disease (SSc-ILD; also known as scleroderma-associated ILD: a lung disease that involves scarring of the lungs) in adults,

• polyarticular juvenile idiopathic arthritis (PJIA; a type of childhood arthritis that affects five or more joints during the first six months of the condition, causing pain, swelling, and loss of function) in children 2 years of age or older.

• systemic juvenile idiopathic arthritis (SJIA; a condition in children that causes inflammation in different areas of the body, causing fever, joint pain and swelling, loss of function, and delays in growth and development) in children 2 years of age or older,

• cytokine release syndrome (a severe and possibly life-threatening reaction) in adults and children 2 years of age or older after receiving certain immunotherapy infusions.

Tocilizumab injection is in a class of medications called interleukin-6 (IL-6) receptor inhibitors. It works by blocking the activity of interleukin-6, a substance in the body that causes inflammation.

Tocilizumab injection comes as a solution (liquid) to be injected intravenously (into a vein) about over 1 hour by a doctor or nurse in a medical office or hospital outpatient clinic or as a prefilled syringe to inject subcutaneously (just under the skin) by yourself at home.

When tocilizumab is given to treat rheumatoid arthritis, it is usually given intravenously once every 4 weeks or subcutaneously once every week or every other week.

When tocilizumab is given to treat giant cell arteritis, it is usually given subcutaneously once every week or every other week.

When tocilizumab is given to treat systemic sclerosis-associated interstitial lung disease, it is usually given subcutaneously once weekly.

When tocilizumab is given to treat polyarticular juvenile idiopathic arthritis, it is usually given intravenously once every 4 weeks or subcutaneously once every 2 or 3 weeks.

When tocilizumab is given to treat systemic juvenile idiopathic arthritis, it is usually given intravenously once every 2 weeks or subcutaneously once every week or once every 2 weeks.

When tocilizumab is given intravenously to treat cytokine release syndrome, it is usually given as one dose, but up to 3 additional doses may be given at least 8 hours apart.

You will receive your first subcutaneous dose of tocilizumab injection in your doctor's office. If you will be injecting tocilizumab injection subcutaneously by yourself at home or having a friend or relative inject the medication for you, your doctor will show you or the person who will be injecting the medication how to inject it. You and the person who will be injecting the medication should also read the written instructions for use that come with the medication.

Thirty minutes before you are ready to inject tocilizumab injection, you will need to remove the medication from the refrigerator, take it out of its carton, and allow it to reach room temperature. When removing a prefilled syringe from the box, be careful not to touch the trigger fingers on the syringe. Do not try to warm the medication by heating it in a microwave, placing it in warm water, or through any other method.

Do not remove the cap from the prefilled syringe while the medication is warming. You should remove the cap no more than 5 minutes before you inject the medication. Do not replace the cap after you remove it. Do not use the syringe if you drop it on the floor.

Check the prefilled syringe to be sure that the expiration date printed on the package has not passed, Holding the syringe with the covered needle pointing down, look closely at the liquid in the syringe. The liquid should be clear or pale yellow and should not be cloudy or discolored or contain lumps or particles. Call your pharmacist if there are any problems with the package or the syringe and do not inject the medication.

You may inject tocilizumab injection on the front of the thighs or anywhere on your stomach except your navel (belly button) and the area 2 inches around it. If another person is injecting your medication, the outer area of the upper arms also may be used. Do not inject the medication into skin that is tender, bruised, red, hard, or not intact, or that has scars, moles, or bruises. Choose a different spot each time you inject the medication, at least 1 inch away from a spot that you have used before. If the full dose is not injected, call your doctor or pharmacist.

Do not reuse tocilizumab prefilled syringes and do not recap the syringes after use. Discard any used syringes in a puncture-resistant container and ask your pharmacist how to throw away the container.

Tocilizumab injection may help control your symptoms, but it will not cure your condition. Your doctor will watch you carefully to see how well tocilizumab injection works for you. Your doctor may adjust your dose or delay your treatment if you have certain changes in your laboratory results. It is important to tell your doctor how you are feeling during your treatment.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before receiving tocilizumab injection,

• tell your doctor and pharmacist if you are allergic to tocilizumab, any other medications, or any of the ingredients in tocilizumab injection. Ask your pharmacist or check the Medication Guide for a list of the ingredients.

• tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin, others) and naproxen (Aleve, Naprosyn, others); cholesterol-lowering medications (statins) such as atorvastatin (Lipitor, in Caduet), lovastatin (Altoprev, in Advicor), and simvastatin (Zocor, in Vytorin); oral contraceptives (birth control pills); or theophylline (Elixophyllin, Theo-24, others). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with tocilizumab injection, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

• tell your doctor if you have or have ever had cancer; diverticulitis (small pouches in the lining of the large intestine that can become inflamed); ulcers in your stomach or intestines; high cholesterol and triglycerides; any condition that affects the nervous system such as multiple sclerosis (MS; a disease in which the nerves do not function properly and people may experience weakness, numbness, loss of muscle coordination and problems with vision, speech, and bladder control) or chronic inflammatory demyelinating polyneuropathy (CIDP; a disorder of the immune and nervous systems); or liver disease.

• tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while receiving tocilizumab injection, call your doctor.

• if you are having surgery, including dental surgery, tell the doctor or dentist that you are receiving tocilizumab injection.

• ask your doctor whether you should receive any vaccinations before you begin your treatment with tocilizumab injection. If possible, all vaccinations for children should be brought up to date before beginning treatment. Do not have any vaccinations during your treatment without talking to your doctor.

Unless your doctor tells you otherwise, continue your normal diet.

If you miss an appointment to receive a tocilizumab infusion, call your doctor.

If you forget to inject a subcutaneous dose of tocilizumab, inject the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not inject a double dose to make up for a missed one. Call your doctor or pharmacist if you do not know when to inject tocilizumab injection.

• Tocilizumab injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • headache

  • runny nose or sneezing

  • redness, itching, pain, or swelling in the place where tocilizumab was injected

• Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately or get emergency medical treatment:

  • rash

  • flushing

  • hives

  • itching

  • swelling of the eyes, face, lips, tongue, throat, arms, hands, feet, ankles, or lower legs

  • difficulty breathing or swallowing

  • chest pain

  • dizziness or fainting

  • fever, ongoing stomach-area pain, or change in bowel habits

  • yellow eyes or skin; right upper abdominal pain; unexplained bruising or bleeding; loss of appetite; confusion; yellow or brown-colored urine; or pale stools

• Tocilizumab may increase the risk of developing certain types of cancer. Talk to your doctor about the risks of receiving this medication.

• Tocilizumab injection may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.

• If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the package it came in, away from light, tightly closed, and out of reach of children. Store tocilizumab injection in the refrigerator, but do not freeze it. Keep the prefilled syringes dry. Discard any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Ask your pharmacist any questions you have about tocilizumab injection.

Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug	Interaction
Repaglinide	Repaglinide The metabolism of Repaglinide can be increased when combined with Tocilizumab.
Montelukast	Montelukast The metabolism of Montelukast can be increased when combined with Tocilizumab.
Leflunomide	Leflunomide The risk or severity of adverse effects can be increased when Tocilizumab is combined with Leflunomide.
Delavirdine	Delavirdine The metabolism of Delavirdine can be increased when combined with Tocilizumab.
Nevirapine	Nevirapine The metabolism of Nevirapine can be increased when combined with Tocilizumab.
Atorvastatin	Atorvastatin The metabolism of Atorvastatin can be increased when combined with Tocilizumab.
Dolasetron	Dolasetron The metabolism of Dolasetron can be increased when combined with Tocilizumab.
Aminophylline	Aminophylline The metabolism of Aminophylline can be increased when combined with Tocilizumab.
Anagrelide	Anagrelide The metabolism of Anagrelide can be increased when combined with Tocilizumab.
Candesartan	Candesartan The metabolism of Candesartan can be increased when combined with Tocilizumab.
Cilostazol	Cilostazol The metabolism of Cilostazol can be increased when combined with Tocilizumab.
Clopidogrel	Clopidogrel The metabolism of Clopidogrel can be increased when combined with Tocilizumab.
Erythromycin and Sulfisoxazole	Erythromycin and Sulfisoxazole The metabolism of Erythromycin can be increased when combined with Tocilizumab.
Estrogen and Progestin (Oral Contraceptives)	Estrogen and Progestin (Oral Contraceptives) The metabolism of Conjugated estrogens can be increased when combined with Tocilizumab.
Fenofibrate	Fenofibrate The metabolism of Fenofibrate can be increased when combined with Tocilizumab.
Mycophenolate	Mycophenolate The risk or severity of adverse effects can be increased when Mycophenolic acid is combined with Tocilizumab.
Paregoric	Paregoric The metabolism of Morphine can be increased when combined with Tocilizumab.
Penbutolol	Penbutolol The metabolism of Acebutolol can be increased when combined with Tocilizumab.
Prednisone	Prednisone The risk or severity of adverse effects can be increased when Prednisone is combined with Tocilizumab.
Ranitidine	Ranitidine The metabolism of Ranitidine can be increased when combined with Tocilizumab.
Tacrolimus	Tacrolimus Tacrolimus may increase the immunosuppressive activities of Tocilizumab.
Tizanidine	Tizanidine The metabolism of Tizanidine can be increased when combined with Tocilizumab.
Triamcinolone	Triamcinolone The metabolism of Triamcinolone can be increased when combined with Tocilizumab.
Zolmitriptan	Zolmitriptan The metabolism of Zolmitriptan can be increased when combined with Tocilizumab.
Hydromorphone Injection	Hydromorphone Injection The metabolism of Hydromorphone can be increased when combined with Tocilizumab.
Interferon Beta-1b Injection	Interferon Beta-1b Injection The risk or severity of adverse effects can be increased when Interferon beta-1b is combined with Tocilizumab.
Interferon Gamma-1b Injection	Interferon Gamma-1b Injection The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Tocilizumab.
Meperidine Injection	Meperidine Injection The metabolism of Meperidine can be increased when combined with Tocilizumab.
Methylprednisolone Injection	Methylprednisolone Injection The risk or severity of adverse effects can be increased when Methylprednisolone is combined with Tocilizumab.
Metoclopramide Injection	Metoclopramide Injection The metabolism of Metoclopramide can be increased when combined with Tocilizumab.
Metronidazole Injection	Metronidazole Injection The metabolism of Metronidazole can be increased when combined with Tocilizumab.
Morphine Injection	Morphine Injection The metabolism of Morphine can be increased when combined with Tocilizumab.
Zidovudine Injection	Zidovudine Injection The metabolism of Zidovudine can be increased when combined with Tocilizumab.
Altretamine	Altretamine The metabolism of Amphetamine can be increased when combined with Tocilizumab.
Cyclosporine	Cyclosporine Tocilizumab may increase the immunosuppressive activities of Cyclosporine.
Ondansetron	Ondansetron The metabolism of Ondansetron can be increased when combined with Tocilizumab.
Torsemide	Torsemide The metabolism of Torasemide can be increased when combined with Tocilizumab.
Olanzapine	Olanzapine The metabolism of Olanzapine can be increased when combined with Tocilizumab.
Alosetron	Alosetron The metabolism of Alosetron can be increased when combined with Tocilizumab.
Dofetilide	Dofetilide The metabolism of Dofetilide can be increased when combined with Tocilizumab.
Hydroxychloroquine	Hydroxychloroquine The metabolism of Tocilizumab can be increased when combined with Hydroxychloroquine.
Meloxicam	Meloxicam The metabolism of Meloxicam can be increased when combined with Tocilizumab.
Pantoprazole	Pantoprazole The metabolism of Pantoprazole can be increased when combined with Tocilizumab.
Temozolomide	Temozolomide The risk or severity of adverse effects can be increased when Temozolomide is combined with Tocilizumab.
Zaleplon	Zaleplon The metabolism of Zaleplon can be increased when combined with Tocilizumab.
Anakinra	Anakinra The risk or severity of adverse effects can be increased when Anakinra is combined with Tocilizumab.
Linezolid	Linezolid The risk or severity of adverse effects can be increased when Linezolid is combined with Tocilizumab.
Trimipramine	Trimipramine The metabolism of Trimipramine can be increased when combined with Tocilizumab.
Etanercept Injection	Etanercept Injection Tocilizumab may increase the immunosuppressive activities of Etanercept.
Tenofovir	Tenofovir The metabolism of Tenofovir can be increased when combined with Tocilizumab.
Sirolimus	Sirolimus The metabolism of Sirolimus can be increased when combined with Tocilizumab.
Dutasteride	Dutasteride The metabolism of Dutasteride can be increased when combined with Tocilizumab.
Epirubicin	Epirubicin The risk or severity of adverse effects can be increased when Epirubicin is combined with Tocilizumab.
Eplerenone	Eplerenone The metabolism of Eplerenone can be increased when combined with Tocilizumab.
Escitalopram	Escitalopram The metabolism of Escitalopram can be increased when combined with Tocilizumab.
Zonisamide	Zonisamide The metabolism of Zonisamide can be increased when combined with Tocilizumab.
Adalimumab Injection	Adalimumab Injection Tocilizumab may increase the immunosuppressive activities of Adalimumab.
Aripiprazole	Aripiprazole The metabolism of Aripiprazole can be increased when combined with Tocilizumab.
Atomoxetine	Atomoxetine The metabolism of Atomoxetine can be increased when combined with Tocilizumab.
Glatiramer Injection	Glatiramer Injection The risk or severity of adverse effects can be increased when Glatiramer is combined with Tocilizumab.
Atazanavir	Atazanavir The metabolism of Atazanavir can be increased when combined with Tocilizumab.
Almotriptan	Almotriptan The metabolism of Almotriptan can be increased when combined with Tocilizumab.
Eletriptan	Eletriptan The metabolism of Eletriptan can be increased when combined with Tocilizumab.
Omalizumab Injection	Omalizumab Injection The risk or severity of adverse effects can be increased when Omalizumab is combined with Tocilizumab.
Rosuvastatin	Rosuvastatin The metabolism of Rosuvastatin can be increased when combined with Tocilizumab.
Vardenafil	Vardenafil The metabolism of Vardenafil can be increased when combined with Tocilizumab.
Aprepitant	Aprepitant The metabolism of Aprepitant can be increased when combined with Tocilizumab.
Tegaserod	Tegaserod The metabolism of Tegaserod can be increased when combined with Tocilizumab.
Tadalafil	Tadalafil The metabolism of Tadalafil can be increased when combined with Tocilizumab.
Frovatriptan	Frovatriptan The metabolism of Frovatriptan can be increased when combined with Tocilizumab.
Progesterone	Progesterone The metabolism of Progesterone can be increased when combined with Tocilizumab.
Apomorphine Injection	Apomorphine Injection The metabolism of Apomorphine can be increased when combined with Tocilizumab.
Infliximab Injection	Infliximab Injection Tocilizumab may increase the immunosuppressive activities of Infliximab.
Protriptyline	Protriptyline The metabolism of Protriptyline can be increased when combined with Tocilizumab.
Duloxetine	Duloxetine The metabolism of Duloxetine can be increased when combined with Tocilizumab.
Norethindrone	Norethindrone The metabolism of Norethisterone can be increased when combined with Tocilizumab.
Bosentan	Bosentan The metabolism of Bosentan can be increased when combined with Tocilizumab.
Cinacalcet	Cinacalcet The metabolism of Cinacalcet can be increased when combined with Tocilizumab.
Natalizumab Injection	Natalizumab Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Natalizumab.
Erlotinib	Erlotinib The serum concentration of Erlotinib can be decreased when it is combined with Tocilizumab.
Eszopiclone	Eszopiclone The serum concentration of Eszopiclone can be decreased when it is combined with Tocilizumab.
Solifenacin	Solifenacin The metabolism of Solifenacin can be increased when combined with Tocilizumab.
Voriconazole	Voriconazole The metabolism of Voriconazole can be increased when combined with Tocilizumab.
Dextroamphetamine	Dextroamphetamine The metabolism of Amphetamine can be increased when combined with Tocilizumab.
Entecavir	Entecavir The metabolism of Entecavir can be increased when combined with Tocilizumab.
Peginterferon Alfa-2a Injection	Peginterferon Alfa-2a Injection The risk or severity of adverse effects can be increased when Peginterferon alfa-2a is combined with Tocilizumab.
Peginterferon Alfa-2b (PEG-Intron)	Peginterferon Alfa-2b (PEG-Intron) The risk or severity of adverse effects can be increased when Peginterferon alfa-2b is combined with Tocilizumab.
Ramelteon	Ramelteon The metabolism of Ramelteon can be increased when combined with Tocilizumab.
Darifenacin	Darifenacin The metabolism of Darifenacin can be increased when combined with Tocilizumab.
Fentanyl	Fentanyl The metabolism of Fentanyl can be increased when combined with Tocilizumab.
Tipranavir	Tipranavir The metabolism of Tipranavir can be increased when combined with Tocilizumab.
Felbamate	Felbamate The metabolism of Felbamate can be increased when combined with Tocilizumab.
Ranolazine	Ranolazine The metabolism of Ranolazine can be increased when combined with Tocilizumab.
Abatacept Injection	Abatacept Injection The risk or severity of adverse effects can be increased when Abatacept is combined with Tocilizumab.
Rasagiline	Rasagiline The metabolism of Rasagiline can be increased when combined with Tocilizumab.
Imatinib	Imatinib The metabolism of Imatinib can be increased when combined with Tocilizumab.
Sitagliptin	Sitagliptin The metabolism of Sitagliptin can be increased when combined with Tocilizumab.
Bevacizumab Injection	Bevacizumab Injection The risk or severity of adverse effects can be increased when Bevacizumab is combined with Tocilizumab.
Gefitinib	Gefitinib The metabolism of Gefitinib can be increased when combined with Tocilizumab.
Paliperidone	Paliperidone The metabolism of Paliperidone can be increased when combined with Tocilizumab.
Bortezomib	Bortezomib The metabolism of Bortezomib can be increased when combined with Tocilizumab.
Clofarabine Injection	Clofarabine Injection The risk or severity of adverse effects can be increased when Clofarabine is combined with Tocilizumab.
Hepatitis B Vaccine	Hepatitis B Vaccine The therapeutic efficacy of Hepatitis B Vaccine (Recombinant) can be decreased when used in combination with Tocilizumab.
Influenza Vaccine, Inactivated or Recombinant	Influenza Vaccine, Inactivated or Recombinant The therapeutic efficacy of Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) can be decreased when used in combination with Tocilizumab.
Influenza Vaccine, Live Intranasal	Influenza Vaccine, Live Intranasal The risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Tocilizumab.
Live Shingles (Zoster) Vaccine (ZVL)	Live Shingles (Zoster) Vaccine (ZVL) The risk or severity of infection can be increased when Varicella Zoster Vaccine (Live/attenuated) is combined with Tocilizumab.
Oxaliplatin Injection	Oxaliplatin Injection The risk or severity of adverse effects can be increased when Oxaliplatin is combined with Tocilizumab.
Primaquine	Primaquine The metabolism of Primaquine can be increased when combined with Tocilizumab.
Rituximab Injection	Rituximab Injection The risk or severity of adverse effects can be increased when Rituximab is combined with Tocilizumab.
Cetuximab Injection	Cetuximab Injection The risk or severity of adverse effects can be increased when Cetuximab is combined with Tocilizumab.
Pemetrexed Injection	Pemetrexed Injection The metabolism of Pemetrexed can be increased when combined with Tocilizumab.
Ranibizumab Injection	Ranibizumab Injection The risk or severity of adverse effects can be increased when Ranibizumab is combined with Tocilizumab.
Lisdexamfetamine	Lisdexamfetamine The metabolism of Lisdexamfetamine can be increased when combined with Tocilizumab.
Retapamulin	Retapamulin The metabolism of Retapamulin can be increased when combined with Tocilizumab.
Vorinostat	Vorinostat The risk or severity of adverse effects can be increased when Vorinostat is combined with Tocilizumab.
Sorafenib	Sorafenib The metabolism of Sorafenib can be increased when combined with Tocilizumab.
Sunitinib	Sunitinib The metabolism of Sunitinib can be increased when combined with Tocilizumab.
Dronabinol	Dronabinol The metabolism of Dronabinol can be increased when combined with Tocilizumab.
Lapatinib	Lapatinib The metabolism of Lapatinib can be increased when combined with Tocilizumab.
Dasatinib	Dasatinib The metabolism of Dasatinib can be increased when combined with Tocilizumab.
Mexiletine	Mexiletine The metabolism of Mexiletine can be increased when combined with Tocilizumab.
Panitumumab Injection	Panitumumab Injection The risk or severity of adverse effects can be increased when Panitumumab is combined with Tocilizumab.
Azacitidine Injection	Azacitidine Injection The risk or severity of adverse effects can be increased when Azacitidine is combined with Tocilizumab.
Temsirolimus	Temsirolimus The metabolism of Temsirolimus can be increased when combined with Tocilizumab.
Nelarabine Injection	Nelarabine Injection The risk or severity of adverse effects can be increased when Nelarabine is combined with Tocilizumab.
Lenalidomide	Lenalidomide The risk or severity of adverse effects can be increased when Lenalidomide is combined with Tocilizumab.
Nilotinib	Nilotinib The metabolism of Tocilizumab can be increased when combined with Nilotinib.
Bexarotene	Bexarotene The metabolism of Bexarotene can be increased when combined with Tocilizumab.
Budesonide	Budesonide The risk or severity of adverse effects can be increased when Budesonide is combined with Tocilizumab.
Chloramphenicol Injection	Chloramphenicol Injection The risk or severity of adverse effects can be increased when Chloramphenicol is combined with Tocilizumab.
Decitabine Injection	Decitabine Injection The risk or severity of adverse effects can be increased when Decitabine is combined with Tocilizumab.
Etravirine	Etravirine The metabolism of Etravirine can be increased when combined with Tocilizumab.
Arsenic Trioxide Injection	Arsenic Trioxide Injection The risk or severity of adverse effects can be increased when Arsenic trioxide is combined with Tocilizumab.
Mitoxantrone Injection	Mitoxantrone Injection The risk or severity of adverse effects can be increased when Mitoxantrone is combined with Tocilizumab.
Cevimeline	Cevimeline The metabolism of Cevimeline can be increased when combined with Tocilizumab.
Nebivolol	Nebivolol The metabolism of Nebivolol can be increased when combined with Tocilizumab.
Tretinoin	Tretinoin The metabolism of Tretinoin can be increased when combined with Tocilizumab.
Bendamustine Injection	Bendamustine Injection The metabolism of Bendamustine can be increased when combined with Tocilizumab.
Flecainide	Flecainide The metabolism of Flecainide can be increased when combined with Tocilizumab.
Certolizumab Injection	Certolizumab Injection Tocilizumab may increase the immunosuppressive activities of Certolizumab pegol.
Ixabepilone Injection	Ixabepilone Injection The metabolism of Tocilizumab can be increased when combined with Ixabepilone.
Irinotecan Injection	Irinotecan Injection The metabolism of Irinotecan can be increased when combined with Tocilizumab.
Estramustine	Estramustine The risk or severity of adverse effects can be increased when Estramustine is combined with Tocilizumab.
Praziquantel	Praziquantel The metabolism of Praziquantel can be increased when combined with Tocilizumab.
Alemtuzumab Injection (Chronic Lymphocytic Leukemia)	Alemtuzumab Injection (Chronic Lymphocytic Leukemia) The risk or severity of adverse effects can be increased when Alemtuzumab is combined with Tocilizumab.
Rufinamide	Rufinamide The metabolism of Rufinamide can be increased when combined with Tocilizumab.
Midazolam	Midazolam The metabolism of Midazolam can be increased when combined with Tocilizumab.
Dexrazoxane Injection	Dexrazoxane Injection The risk or severity of adverse effects can be increased when Dexrazoxane is combined with Tocilizumab.
Eltrombopag	Eltrombopag The metabolism of Eltrombopag can be increased when combined with Tocilizumab.
Ibritumomab Injection	Ibritumomab Injection The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with Tocilizumab.
Milnacipran	Milnacipran The metabolism of Milnacipran can be increased when combined with Tocilizumab.
Dexlansoprazole	Dexlansoprazole The metabolism of Dexlansoprazole can be increased when combined with Tocilizumab.
Fesoterodine	Fesoterodine The metabolism of Fesoterodine can be increased when combined with Tocilizumab.
Betaxolol	Betaxolol The metabolism of Betaxolol can be increased when combined with Tocilizumab.
Iloperidone	Iloperidone The metabolism of Iloperidone can be increased when combined with Tocilizumab.
Prasugrel	Prasugrel The metabolism of Prasugrel can be increased when combined with Tocilizumab.
Lacosamide	Lacosamide The metabolism of Lacosamide can be increased when combined with Tocilizumab.
Everolimus	Everolimus The metabolism of Everolimus can be increased when combined with Tocilizumab.
Tolvaptan (low blood sodium)	Tolvaptan (low blood sodium) The metabolism of Tolvaptan can be increased when combined with Tocilizumab.
Dronedarone	Dronedarone The metabolism of Dronedarone can be increased when combined with Tocilizumab.
Pralatrexate Injection	Pralatrexate Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Pralatrexate.
Palonosetron Injection	Palonosetron Injection The metabolism of Palonosetron can be increased when combined with Tocilizumab.
Saxagliptin	Saxagliptin The metabolism of Saxagliptin can be increased when combined with Tocilizumab.
Romidepsin Injection	Romidepsin Injection The metabolism of Romidepsin can be increased when combined with Tocilizumab.
Tapentadol	Tapentadol The metabolism of Tapentadol can be increased when combined with Tocilizumab.
Topotecan	Topotecan The risk or severity of adverse effects can be increased when Topotecan is combined with Tocilizumab.
Ofatumumab Injection (Chronic Lymphocytic Leukemia)	Ofatumumab Injection (Chronic Lymphocytic Leukemia) The risk or severity of adverse effects can be increased when Tocilizumab is combined with Ofatumumab.
Golimumab Injection	Golimumab Injection Tocilizumab may increase the immunosuppressive activities of Golimumab.
Pazopanib	Pazopanib The metabolism of Pazopanib can be increased when combined with Tocilizumab.
Asenapine	Asenapine The metabolism of Asenapine can be increased when combined with Tocilizumab.
Pitavastatin	Pitavastatin The metabolism of Pitavastatin can be increased when combined with Tocilizumab.
Albendazole	Albendazole The metabolism of Albendazole can be increased when combined with Tocilizumab.
Ulipristal	Ulipristal The metabolism of Ulipristal can be increased when combined with Tocilizumab.
Levonorgestrel	Levonorgestrel The metabolism of Levonorgestrel can be increased when combined with Tocilizumab.
Oxymorphone	Oxymorphone The metabolism of Oxymorphone can be increased when combined with Tocilizumab.
Denosumab Injection	Denosumab Injection The risk or severity of adverse effects can be increased when Denosumab is combined with Tocilizumab.
Fingolimod	Fingolimod Tocilizumab may increase the immunosuppressive activities of Fingolimod.
Eribulin Injection	Eribulin Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Eribulin.
Cabazitaxel Injection	Cabazitaxel Injection The metabolism of Cabazitaxel can be increased when combined with Tocilizumab.
Ustekinumab Injection	Ustekinumab Injection The risk or severity of adverse effects can be increased when Ustekinumab is combined with Tocilizumab.
Acetaminophen Injection	Acetaminophen Injection The metabolism of Acetaminophen can be increased when combined with Tocilizumab.
Vilazodone	Vilazodone The metabolism of Vilazodone can be increased when combined with Tocilizumab.
Ipilimumab Injection	Ipilimumab Injection The risk or severity of adverse effects can be increased when Ipilimumab is combined with Tocilizumab.
Denileukin Diftitox Injection	Denileukin Diftitox Injection The risk or severity of adverse effects can be increased when Aldesleukin is combined with Tocilizumab.
Sipuleucel-T Injection	Sipuleucel-T Injection The therapeutic efficacy of Sipuleucel-T can be decreased when used in combination with Tocilizumab.
Belimumab Injection	Belimumab Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Belimumab.
Busulfan Injection	Busulfan Injection The metabolism of Busulfan can be increased when combined with Tocilizumab.
Roflumilast	Roflumilast Tocilizumab may increase the immunosuppressive activities of Roflumilast.
Linagliptin	Linagliptin The metabolism of Linagliptin can be increased when combined with Tocilizumab.
Cyclophosphamide Injection	Cyclophosphamide Injection The metabolism of Cyclophosphamide can be increased when combined with Tocilizumab.
Rivaroxaban	Rivaroxaban The metabolism of Rivaroxaban can be increased when combined with Tocilizumab.
Brentuximab Vedotin Injection	Brentuximab Vedotin Injection The metabolism of Brentuximab vedotin can be increased when combined with Tocilizumab.
Ruxolitinib	Ruxolitinib The metabolism of Ruxolitinib can be increased when combined with Tocilizumab.
Vandetanib	Vandetanib The metabolism of Vandetanib can be increased when combined with Tocilizumab.
Clobazam	Clobazam The metabolism of Clobazam can be increased when combined with Tocilizumab.
Vemurafenib	Vemurafenib The metabolism of Vemurafenib can be increased when combined with Tocilizumab.
Vismodegib	Vismodegib The metabolism of Vismodegib can be increased when combined with Tocilizumab.
Belatacept Injection	Belatacept Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Belatacept.
Ivacaftor	Ivacaftor The metabolism of Ivacaftor can be increased when combined with Tocilizumab.
Basiliximab Injection	Basiliximab Injection The risk or severity of adverse effects can be increased when Basiliximab is combined with Tocilizumab.
Axitinib	Axitinib The metabolism of Axitinib can be increased when combined with Tocilizumab.
Crizotinib	Crizotinib The metabolism of Crizotinib can be increased when combined with Tocilizumab.
Melphalan Injection	Melphalan Injection The risk or severity of adverse effects can be increased when Melphalan is combined with Tocilizumab.
Cabergoline	Cabergoline The metabolism of Cabergoline can be increased when combined with Tocilizumab.
Ambrisentan	Ambrisentan The metabolism of Ambrisentan can be increased when combined with Tocilizumab.
Eculizumab Injection	Eculizumab Injection The risk or severity of adverse effects can be increased when Eculizumab is combined with Tocilizumab.
Pertuzumab Injection	Pertuzumab Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Pertuzumab.
Carfilzomib Injection	Carfilzomib Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Carfilzomib.
Enzalutamide	Enzalutamide The metabolism of Enzalutamide can be increased when combined with Tocilizumab.
Mirabegron	Mirabegron The metabolism of Mirabegron can be increased when combined with Tocilizumab.
Regorafenib	Regorafenib The metabolism of Regorafenib can be increased when combined with Tocilizumab.
Bosutinib	Bosutinib The metabolism of Bosutinib can be increased when combined with Tocilizumab.
Corticotropin, Repository Injection	Corticotropin, Repository Injection The risk or severity of adverse effects can be increased when Corticotropin is combined with Tocilizumab.
Teriflunomide	Teriflunomide The risk or severity of adverse effects can be increased when Tocilizumab is combined with Teriflunomide.
Cabozantinib (thyroid cancer)	Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be increased when combined with Tocilizumab.
Tofacitinib	Tofacitinib The risk or severity of adverse effects can be increased when Tocilizumab is combined with Tofacitinib.
Alogliptin	Alogliptin The metabolism of Alogliptin can be increased when combined with Tocilizumab.
Dimethyl Fumarate	Dimethyl Fumarate The risk or severity of adverse effects can be increased when Tocilizumab is combined with Dimethyl fumarate.
Ponatinib	Ponatinib The metabolism of Ponatinib can be increased when combined with Tocilizumab.
Pomalidomide	Pomalidomide The metabolism of Pomalidomide can be increased when combined with Tocilizumab.
Ado-trastuzumab Emtansine Injection	Ado-trastuzumab Emtansine Injection The metabolism of Trastuzumab emtansine can be increased when combined with Tocilizumab.
Apixaban	Apixaban The metabolism of Apixaban can be increased when combined with Tocilizumab.
Dabrafenib	Dabrafenib The metabolism of Dabrafenib can be increased when combined with Tocilizumab.
Ospemifene	Ospemifene The metabolism of Ospemifene can be increased when combined with Tocilizumab.
Levomilnacipran	Levomilnacipran The metabolism of Levomilnacipran can be increased when combined with Tocilizumab.
Vortioxetine	Vortioxetine The metabolism of Vortioxetine can be increased when combined with Tocilizumab.
Perampanel	Perampanel The metabolism of Perampanel can be increased when combined with Tocilizumab.
Ibrutinib	Ibrutinib The metabolism of Ibrutinib can be increased when combined with Tocilizumab.
Lomitapide	Lomitapide The metabolism of Lomitapide can be increased when combined with Tocilizumab.
Ketorolac Injection	Ketorolac Injection The metabolism of Ketorolac can be increased when combined with Tocilizumab.
Obinutuzumab Injection	Obinutuzumab Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Obinutuzumab.
Dapagliflozin	Dapagliflozin The metabolism of Dapagliflozin can be increased when combined with Tocilizumab.
Apremilast	Apremilast The therapeutic efficacy of Apremilast can be decreased when used in combination with Tocilizumab.
Ramucirumab Injection	Ramucirumab Injection The risk or severity of adverse effects can be increased when Ramucirumab is combined with Tocilizumab.
Ceritinib	Ceritinib The metabolism of Ceritinib can be increased when combined with Tocilizumab.
Siltuximab Injection	Siltuximab Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Siltuximab.
Vedolizumab Injection	Vedolizumab Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Vedolizumab.
Belinostat Injection	Belinostat Injection The risk or severity of adverse effects can be increased when Belinostat is combined with Tocilizumab.
Idelalisib	Idelalisib The metabolism of Idelalisib can be increased when combined with Tocilizumab.
Testosterone Injection	Testosterone Injection The metabolism of Testosterone can be increased when combined with Tocilizumab.
Vorapaxar	Vorapaxar The metabolism of Vorapaxar can be increased when combined with Tocilizumab.
Hydrocodone	Hydrocodone The metabolism of Hydrocodone can be increased when combined with Tocilizumab.
Suvorexant	Suvorexant The metabolism of Suvorexant can be increased when combined with Tocilizumab.
Dulaglutide Injection	Dulaglutide Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Dulaglutide.
Pembrolizumab Injection	Pembrolizumab Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Pembrolizumab.
Nivolumab Injection	Nivolumab Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Nivolumab.
Peginterferon Beta-1a Injection	Peginterferon Beta-1a Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Peginterferon beta-1a.
Olaparib	Olaparib The metabolism of Olaparib can be increased when combined with Tocilizumab.
Blinatumomab Injection	Blinatumomab Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Blinatumomab.
Methamphetamine	Methamphetamine The metabolism of Metamfetamine can be increased when combined with Tocilizumab.
Tasimelteon	Tasimelteon The metabolism of Tasimelteon can be increased when combined with Tocilizumab.
Riociguat	Riociguat The metabolism of Riociguat can be increased when combined with Tocilizumab.
Pirfenidone	Pirfenidone The metabolism of Pirfenidone can be increased when combined with Tocilizumab.
Nintedanib	Nintedanib The metabolism of Nintedanib can be increased when combined with Tocilizumab.
Secukinumab Injection	Secukinumab Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Secukinumab.
Risperidone Injection	Risperidone Injection The metabolism of Risperidone can be increased when combined with Tocilizumab.
Palbociclib	Palbociclib The metabolism of Palbociclib can be increased when combined with Tocilizumab.
Panobinostat	Panobinostat The metabolism of Panobinostat can be increased when combined with Tocilizumab.
Dinutuximab Injection	Dinutuximab Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Dinutuximab.
Haloperidol Injection	Haloperidol Injection The metabolism of Haloperidol can be increased when combined with Tocilizumab.
Sonidegib	Sonidegib The metabolism of Sonidegib can be increased when combined with Tocilizumab.
Alirocumab Injection	Alirocumab Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Alirocumab.
Prednisolone	Prednisolone The risk or severity of adverse effects can be increased when Prednisolone is combined with Tocilizumab.
Evolocumab Injection	Evolocumab Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Evolocumab.
Daclatasvir	Daclatasvir The metabolism of Daclatasvir can be increased when combined with Tocilizumab.
Brexpiprazole	Brexpiprazole The metabolism of Brexpiprazole can be increased when combined with Tocilizumab.
Ziprasidone Injection	Ziprasidone Injection The metabolism of Ziprasidone can be increased when combined with Tocilizumab.
Cariprazine	Cariprazine The metabolism of Cariprazine can be increased when combined with Tocilizumab.
Cobimetinib	Cobimetinib The metabolism of Cobimetinib can be increased when combined with Tocilizumab.
Mepolizumab Injection	Mepolizumab Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Mepolizumab.
Trabectedin Injection	Trabectedin Injection The metabolism of Trabectedin can be increased when combined with Tocilizumab.
Elotuzumab Injection	Elotuzumab Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Elotuzumab.
Daratumumab Injection	Daratumumab Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Daratumumab.
Osimertinib	Osimertinib The metabolism of Osimertinib can be increased when combined with Tocilizumab.
Alectinib	Alectinib The metabolism of Alectinib can be increased when combined with Tocilizumab.
Ixazomib	Ixazomib The metabolism of Ixazomib can be increased when combined with Tocilizumab.
Necitumumab Injection	Necitumumab Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Necitumumab.
Lesinurad	Lesinurad The metabolism of Lesinurad can be increased when combined with Tocilizumab.
Dexamethasone Injection	Dexamethasone Injection The metabolism of Tocilizumab can be increased when combined with Dexamethasone.
Reslizumab Injection	Reslizumab Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Reslizumab.
Ixekizumab Injection	Ixekizumab Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Ixekizumab.
Brivaracetam Injection	Brivaracetam Injection The metabolism of Brivaracetam can be increased when combined with Tocilizumab.
Venetoclax	Venetoclax The metabolism of Venetoclax can be increased when combined with Tocilizumab.
Cobicistat	Cobicistat The metabolism of Cobicistat can be increased when combined with Tocilizumab.
Selexipag	Selexipag The metabolism of Selexipag can be increased when combined with Tocilizumab.
Atezolizumab Injection	Atezolizumab Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Atezolizumab.
Diphenhydramine Injection	Diphenhydramine Injection The metabolism of Diphenhydramine can be increased when combined with Tocilizumab.
Olaratumab Injection	Olaratumab Injection The risk or severity of adverse effects can be increased when Olaratumab is combined with Tocilizumab.
Rucaparib	Rucaparib The metabolism of Rucaparib can be increased when combined with Tocilizumab.
Bezlotoxumab Injection	Bezlotoxumab Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Bezlotoxumab.
Avelumab Injection	Avelumab Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Avelumab.
Ribociclib	Ribociclib The metabolism of Ribociclib can be increased when combined with Tocilizumab.
Brodalumab Injection	Brodalumab Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Brodalumab.
Brigatinib	Brigatinib The metabolism of Brigatinib can be increased when combined with Tocilizumab.
Doxepin (Insomnia)	Doxepin (Insomnia) The metabolism of Doxepin can be increased when combined with Tocilizumab.
Dupilumab Injection	Dupilumab Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Dupilumab.
Deutetrabenazine	Deutetrabenazine The metabolism of Deutetrabenazine can be increased when combined with Tocilizumab.
Valbenazine	Valbenazine The metabolism of Valbenazine can be increased when combined with Tocilizumab.
Deflazacort	Deflazacort The risk or severity of adverse effects can be increased when Tocilizumab is combined with Deflazacort.
Ocrelizumab Injection	Ocrelizumab Injection Ocrelizumab may increase the immunosuppressive activities of Tocilizumab.
Durvalumab Injection	Durvalumab Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Durvalumab.
Sarilumab Injection	Sarilumab Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Sarilumab.
Midostaurin	Midostaurin The metabolism of Midostaurin can be increased when combined with Tocilizumab.
Neratinib	Neratinib The metabolism of Neratinib can be increased when combined with Tocilizumab.
Guselkumab Injection	Guselkumab Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Guselkumab.
Enasidenib	Enasidenib The metabolism of Enasidenib can be increased when combined with Tocilizumab.
Inotuzumab Ozogamicin Injection	Inotuzumab Ozogamicin Injection The risk or severity of adverse effects can be increased when Inotuzumab ozogamicin is combined with Tocilizumab.
Aprepitant/Fosaprepitant Injection	Aprepitant/Fosaprepitant Injection The metabolism of Fosaprepitant can be increased when combined with Tocilizumab.
Copanlisib Injection	Copanlisib Injection The metabolism of Copanlisib can be increased when combined with Tocilizumab.
Abemaciclib	Abemaciclib The metabolism of Abemaciclib can be increased when combined with Tocilizumab.
Benralizumab Injection	Benralizumab Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Benralizumab.
Acalabrutinib	Acalabrutinib The metabolism of Acalabrutinib can be increased when combined with Tocilizumab.
Gemtuzumab Ozogamicin Injection	Gemtuzumab Ozogamicin Injection The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Tocilizumab.
Letermovir	Letermovir The metabolism of Letermovir can be increased when combined with Tocilizumab.
Tetrabenazine	Tetrabenazine The metabolism of Tetrabenazine can be increased when combined with Tocilizumab.
Buprenorphine Injection	Buprenorphine Injection The metabolism of Buprenorphine can be increased when combined with Tocilizumab.
Apalutamide	Apalutamide The metabolism of Apalutamide can be increased when combined with Tocilizumab.
Ibalizumab-uiyk Injection	Ibalizumab-uiyk Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Ibalizumab.
Penicillamine	Penicillamine The risk or severity of adverse effects can be increased when Penicillamine is combined with Tocilizumab.
Tildrakizumab-asmn injection	Tildrakizumab-asmn injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Tildrakizumab.
Erenumab-aooe Injection	Erenumab-aooe Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Erenumab.
Baricitinib	Baricitinib The metabolism of Baricitinib can be increased when combined with Tocilizumab.
Burosumab-twza Injection	Burosumab-twza Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Burosumab.
Lofexidine	Lofexidine The metabolism of Lofexidine can be increased when combined with Tocilizumab.
Eliglustat	Eliglustat The metabolism of Eliglustat can be increased when combined with Tocilizumab.
Encorafenib	Encorafenib The metabolism of Encorafenib can be increased when combined with Tocilizumab.
Binimetinib	Binimetinib The metabolism of Binimetinib can be increased when combined with Tocilizumab.
Ivosidenib	Ivosidenib The metabolism of Ivosidenib can be increased when combined with Tocilizumab.
Elagolix	Elagolix The metabolism of Elagolix can be increased when combined with Tocilizumab.
Doravirine	Doravirine The metabolism of Doravirine can be increased when combined with Tocilizumab.
Tafenoquine	Tafenoquine The metabolism of Tafenoquine can be increased when combined with Tocilizumab.
Cannabidiol	Cannabidiol The metabolism of Cannabidiol can be increased when combined with Tocilizumab.
Cemiplimab-rwlc Injection	Cemiplimab-rwlc Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Cemiplimab.
Dacomitinib	Dacomitinib The metabolism of Dacomitinib can be increased when combined with Tocilizumab.
Duvelisib	Duvelisib The metabolism of Duvelisib can be increased when combined with Tocilizumab.
Galcanezumab-gnlm Injection	Galcanezumab-gnlm Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Galcanezumab.
Mogamulizumab-kpkc Injection	Mogamulizumab-kpkc Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Mogamulizumab.
Stiripentol	Stiripentol The metabolism of Stiripentol can be increased when combined with Tocilizumab.
Gilteritinib	Gilteritinib The metabolism of Gilteritinib can be increased when combined with Tocilizumab.
Glasdegib	Glasdegib The metabolism of Glasdegib can be increased when combined with Tocilizumab.
Lorlatinib	Lorlatinib The metabolism of Lorlatinib can be increased when combined with Tocilizumab.
Paclitaxel (with albumin) Injection	Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be increased when combined with Tocilizumab.
Prucalopride	Prucalopride The metabolism of Prucalopride can be increased when combined with Tocilizumab.
Ravulizumab-cwvz Injection	Ravulizumab-cwvz Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Ravulizumab.
Emapalumab-lzsg Injection	Emapalumab-lzsg Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Emapalumab.
Romosozumab-aqqg Injection	Romosozumab-aqqg Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Romosozumab.
Siponimod	Siponimod The metabolism of Siponimod can be increased when combined with Tocilizumab.
Acyclovir Ophthalmic	Acyclovir Ophthalmic The metabolism of Acyclovir can be increased when combined with Tocilizumab.
Caplacizumab-yhdp Injection	Caplacizumab-yhdp Injection The risk or severity of adverse effects can be increased when Caplacizumab is combined with Tocilizumab.
Erdafitinib	Erdafitinib The metabolism of Erdafitinib can be increased when combined with Tocilizumab.
Esomeprazole Injection	Esomeprazole Injection The metabolism of Esomeprazole can be increased when combined with Tocilizumab.
Risankizumab-rzaa Injection	Risankizumab-rzaa Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Risankizumab.
Alpelisib	Alpelisib The metabolism of Alpelisib can be increased when combined with Tocilizumab.
Cladribine	Cladribine The risk or severity of adverse effects can be increased when Cladribine is combined with Tocilizumab.
Polatuzumab vedotin-piiq Injection	Polatuzumab vedotin-piiq Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Polatuzumab vedotin.
Triclabendazole	Triclabendazole The metabolism of Triclabendazole can be increased when combined with Tocilizumab.
Entrectinib	Entrectinib The metabolism of Entrectinib can be increased when combined with Tocilizumab.
Pexidartinib	Pexidartinib The metabolism of Pexidartinib can be increased when combined with Tocilizumab.
Istradefylline	Istradefylline The metabolism of Istradefylline can be increased when combined with Tocilizumab.
Pitolisant	Pitolisant The metabolism of Pitolisant can be increased when combined with Tocilizumab.
Fedratinib	Fedratinib The metabolism of Fedratinib can be increased when combined with Tocilizumab.
Lefamulin	Lefamulin The metabolism of Lefamulin can be increased when combined with Tocilizumab.
Phenytoin Injection	Phenytoin Injection The metabolism of Phenytoin can be increased when combined with Tocilizumab.
Fosphenytoin Injection	Fosphenytoin Injection The metabolism of Fosphenytoin can be increased when combined with Tocilizumab.
Brolucizumab-dbll Injection	Brolucizumab-dbll Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Brolucizumab.
Fam-trastuzumab deruxtecan-nxki Injection	Fam-trastuzumab deruxtecan-nxki Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Trastuzumab deruxtecan.
Zanubrutinib	Zanubrutinib The metabolism of Zanubrutinib can be increased when combined with Tocilizumab.
Voxelotor	Voxelotor The metabolism of Voxelotor can be increased when combined with Tocilizumab.
Avapritinib	Avapritinib The metabolism of Avapritinib can be increased when combined with Tocilizumab.
Lumateperone	Lumateperone The serum concentration of Lumateperone can be decreased when it is combined with Tocilizumab.
Ubrogepant	Ubrogepant The serum concentration of Ubrogepant can be decreased when it is combined with Tocilizumab.
Tazemetostat	Tazemetostat The metabolism of Tazemetostat can be increased when combined with Tocilizumab.
Cenobamate	Cenobamate The metabolism of Cenobamate can be increased when combined with Tocilizumab.
Isatuximab-irfc Injection	Isatuximab-irfc Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Isatuximab.
Teprotumumab-trbw Injection	Teprotumumab-trbw Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Teprotumumab.
Ozanimod	Ozanimod The risk or severity of adverse effects can be increased when Tocilizumab is combined with Ozanimod.
Selumetinib	Selumetinib The metabolism of Selumetinib can be increased when combined with Tocilizumab.
Rimegepant	Rimegepant The metabolism of Rimegepant can be increased when combined with Tocilizumab.
Tucatinib	Tucatinib The metabolism of Tucatinib can be increased when combined with Tocilizumab.
Sacituzumab govitecan-hziy Injection	Sacituzumab govitecan-hziy Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Sacituzumab govitecan.
Selpercatinib	Selpercatinib The serum concentration of Selpercatinib can be decreased when it is combined with Tocilizumab.
Capmatinib	Capmatinib The serum concentration of Capmatinib can be decreased when it is combined with Tocilizumab.
Lemborexant	Lemborexant The serum concentration of Lemborexant can be decreased when it is combined with Tocilizumab.
Luspatercept-aamt Injection	Luspatercept-aamt Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Luspatercept.
Belantamab Mafodotin-blmf Injection	Belantamab Mafodotin-blmf Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Belantamab mafodotin.
Tafasitamab-cxix Injection	Tafasitamab-cxix Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Tafasitamab.
Margetuximab-cmkb Injection	Margetuximab-cmkb Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Margetuximab.
Progestin-Only (drospirenone) Oral Contraceptives	Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Drospirenone can be increased when combined with Tocilizumab.
Evinacumab-dgnb Injection	Evinacumab-dgnb Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Evinacumab.
Aducanumab-avwa Injection	Aducanumab-avwa Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Aducanumab.
Anifrolumab-fnia Injection	Anifrolumab-fnia Injection The risk or severity of adverse effects can be increased when Tocilizumab is combined with Anifrolumab.
Theophylline	Theophylline The metabolism of Theophylline can be increased when combined with Tocilizumab.
Indomethacin	Indomethacin The metabolism of Indomethacin can be increased when combined with Tocilizumab.
Mefenamic Acid	Mefenamic Acid The metabolism of Mefenamic acid can be increased when combined with Tocilizumab.
Naproxen	Naproxen The metabolism of Naproxen can be increased when combined with Tocilizumab.
Trazodone	Trazodone The metabolism of Trazodone can be increased when combined with Tocilizumab.
Hydroxyurea	Hydroxyurea The risk or severity of adverse effects can be increased when Hydroxyurea is combined with Tocilizumab.
Floxuridine	Floxuridine The risk or severity of adverse effects can be increased when Floxuridine is combined with Tocilizumab.
Phenobarbital	Phenobarbital The metabolism of Phenobarbital can be increased when combined with Tocilizumab.
Methotrexate Injection	Methotrexate Injection The metabolism of Tocilizumab can be increased when combined with Methotrexate.
Primidone	Primidone The metabolism of Primidone can be increased when combined with Tocilizumab.
Methsuximide	Methsuximide The metabolism of Methsuximide can be increased when combined with Tocilizumab.
Chlorpromazine	Chlorpromazine The metabolism of Chlorpromazine can be increased when combined with Tocilizumab.
Diazepam	Diazepam The metabolism of Diazepam can be increased when combined with Tocilizumab.
Flurazepam	Flurazepam The metabolism of Flurazepam can be increased when combined with Tocilizumab.
Lorazepam	Lorazepam The metabolism of Lorazepam can be increased when combined with Tocilizumab.
Carmustine	Carmustine The metabolism of Carmustine can be increased when combined with Tocilizumab.
Codeine	Codeine The metabolism of Codeine can be increased when combined with Tocilizumab.
Procarbazine	Procarbazine The risk or severity of adverse effects can be increased when Procarbazine is combined with Tocilizumab.
Thioguanine	Thioguanine The risk or severity of adverse effects can be increased when Tioguanine is combined with Tocilizumab.
Prochlorperazine	Prochlorperazine The metabolism of Prochlorperazine can be increased when combined with Tocilizumab.
Thioridazine	Thioridazine The metabolism of Thioridazine can be increased when combined with Tocilizumab.
Trifluoperazine	Trifluoperazine The metabolism of Trifluoperazine can be increased when combined with Tocilizumab.
Bleomycin	Bleomycin The risk or severity of adverse effects can be increased when Bleomycin is combined with Tocilizumab.
Dapsone	Dapsone The metabolism of Dapsone can be increased when combined with Tocilizumab.
Sulfadiazine	Sulfadiazine The metabolism of Sulfadiazine can be increased when combined with Tocilizumab.
Oxycodone	Oxycodone The metabolism of Oxycodone can be increased when combined with Tocilizumab.
Methadone	Methadone The metabolism of Methadone can be increased when combined with Tocilizumab.
Oxybutynin	Oxybutynin The metabolism of Oxybutynin can be increased when combined with Tocilizumab.
Benztropine	Benztropine The metabolism of Benzatropine can be increased when combined with Tocilizumab.
Maprotiline	Maprotiline The metabolism of Maprotiline can be increased when combined with Tocilizumab.
Ibuprofen	Ibuprofen The metabolism of Ibuprofen can be increased when combined with Tocilizumab.
Perphenazine	Perphenazine The metabolism of Perphenazine can be increased when combined with Tocilizumab.
Azathioprine	Azathioprine The metabolism of Azathioprine can be increased when combined with Tocilizumab.
Phentermine	Phentermine The metabolism of Phentermine can be increased when combined with Tocilizumab.
Amoxapine	Amoxapine The metabolism of Amoxapine can be increased when combined with Tocilizumab.
Sulfasalazine	Sulfasalazine The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Tocilizumab.
Hydrocortisone	Hydrocortisone The metabolism of Hydrocortisone can be increased when combined with Tocilizumab.
Lomustine	Lomustine The risk or severity of adverse effects can be increased when Lomustine is combined with Tocilizumab.
Doxorubicin	Doxorubicin The metabolism of Tocilizumab can be increased when combined with Doxorubicin.
Cytarabine	Cytarabine The risk or severity of adverse effects can be increased when Cytarabine is combined with Tocilizumab.
Mechlorethamine	Mechlorethamine The risk or severity of adverse effects can be increased when Mechlorethamine is combined with Tocilizumab.
Dactinomycin	Dactinomycin The risk or severity of adverse effects can be increased when Dactinomycin is combined with Tocilizumab.
Carbamazepine	Carbamazepine The metabolism of Tocilizumab can be increased when combined with Carbamazepine.
Clonidine	Clonidine The metabolism of Clonidine can be increased when combined with Tocilizumab.
Warfarin	Warfarin The metabolism of Warfarin can be increased when combined with Tocilizumab.
Clonazepam	Clonazepam The metabolism of Clonazepam can be increased when combined with Tocilizumab.
Loperamide	Loperamide The metabolism of Loperamide can be increased when combined with Tocilizumab.
Promethazine	Promethazine The metabolism of Promethazine can be increased when combined with Tocilizumab.
Daunorubicin	Daunorubicin The risk or severity of adverse effects can be increased when Daunorubicin is combined with Tocilizumab.
Chloroquine	Chloroquine The metabolism of Chloroquine can be increased when combined with Tocilizumab.
Quinine	Quinine The metabolism of Quinine can be increased when combined with Tocilizumab.
Ethosuximide	Ethosuximide The metabolism of Ethosuximide can be increased when combined with Tocilizumab.
Triamterene	Triamterene The metabolism of Triamterene can be increased when combined with Tocilizumab.
Isosorbide	Isosorbide The metabolism of Isosorbide can be increased when combined with Tocilizumab.
Clindamycin Injection	Clindamycin Injection The metabolism of Clindamycin can be increased when combined with Tocilizumab.
Desipramine	Desipramine The metabolism of Desipramine can be increased when combined with Tocilizumab.
Amitriptyline	Amitriptyline The metabolism of Amitriptyline can be increased when combined with Tocilizumab.
Imipramine	Imipramine The metabolism of Imipramine can be increased when combined with Tocilizumab.
Quinidine	Quinidine The metabolism of Quinidine can be increased when combined with Tocilizumab.
Procainamide	Procainamide The metabolism of Procainamide can be increased when combined with Tocilizumab.
Disopyramide	Disopyramide The metabolism of Disopyramide can be increased when combined with Tocilizumab.
Valproic Acid	Valproic Acid The metabolism of Valproic acid can be increased when combined with Tocilizumab.
Tamoxifen	Tamoxifen The metabolism of Tamoxifen can be increased when combined with Tocilizumab.
Mitomycin	Mitomycin The risk or severity of adverse effects can be increased when Mitomycin is combined with Tocilizumab.
Methimazole	Methimazole The risk or severity of adverse effects can be increased when Methimazole is combined with Tocilizumab.
Propylthiouracil	Propylthiouracil The risk or severity of adverse effects can be increased when Propylthiouracil is combined with Tocilizumab.
Chlorpropamide	Chlorpropamide The metabolism of Chlorpropamide can be increased when combined with Tocilizumab.
Tolbutamide	Tolbutamide The metabolism of Tolbutamide can be increased when combined with Tocilizumab.
Tolazamide	Tolazamide The metabolism of Tolazamide can be increased when combined with Tocilizumab.
Dextromethorphan	Dextromethorphan The metabolism of Dextromethorphan can be increased when combined with Tocilizumab.
Cyclobenzaprine	Cyclobenzaprine The metabolism of Cyclobenzaprine can be increased when combined with Tocilizumab.
Chlorpheniramine	Chlorpheniramine The metabolism of Chlorpheniramine can be increased when combined with Tocilizumab.
Brompheniramine	Brompheniramine The metabolism of Brompheniramine can be increased when combined with Tocilizumab.
Meclizine	Meclizine The metabolism of Meclizine can be increased when combined with Tocilizumab.
Chlorzoxazone	Chlorzoxazone The metabolism of Chlorzoxazone can be increased when combined with Tocilizumab.
Carisoprodol	Carisoprodol The metabolism of Carisoprodol can be increased when combined with Tocilizumab.
Disulfiram	Disulfiram The metabolism of Disulfiram can be increased when combined with Tocilizumab.
Propranolol (Cardiovascular)	Propranolol (Cardiovascular) The metabolism of Propranolol can be increased when combined with Tocilizumab.
Nortriptyline	Nortriptyline The metabolism of Nortriptyline can be increased when combined with Tocilizumab.
Mercaptopurine	Mercaptopurine The risk or severity of adverse effects can be increased when Mercaptopurine is combined with Tocilizumab.
Nadolol	Nadolol The metabolism of Nadolol can be increased when combined with Tocilizumab.
Fluorouracil Injection	Fluorouracil Injection The metabolism of Fluorouracil can be increased when combined with Tocilizumab.
Colchicine	Colchicine The risk or severity of adverse effects can be increased when Colchicine is combined with Tocilizumab.
Cephalexin	Cephalexin The metabolism of Cephalexin can be increased when combined with Tocilizumab.
Dacarbazine	Dacarbazine The metabolism of Dacarbazine can be increased when combined with Tocilizumab.
Bacillus Calmette-Guerin (BCG) Vaccine	Bacillus Calmette-Guerin (BCG) Vaccine The risk or severity of infection can be increased when Bacillus calmette-guerin substrain tice live antigen is combined with Tocilizumab.
Thiotepa Injection	Thiotepa Injection The metabolism of Tocilizumab can be increased when combined with Thiotepa.
Vincristine Injection	Vincristine Injection The metabolism of Vincristine can be increased when combined with Tocilizumab.
Vinblastine	Vinblastine The metabolism of Tocilizumab can be increased when combined with Vinblastine.
Metoprolol	Metoprolol The metabolism of Metoprolol can be increased when combined with Tocilizumab.
Hydroxyzine	Hydroxyzine The metabolism of Hydroxyzine can be increased when combined with Tocilizumab.
Thiothixene	Thiothixene The metabolism of Thiothixene can be increased when combined with Tocilizumab.
Aspirin	Aspirin The metabolism of Acetylsalicylic acid can be increased when combined with Tocilizumab.
Chlorambucil	Chlorambucil The risk or severity of adverse effects can be increased when Chlorambucil is combined with Tocilizumab.
Alprazolam	Alprazolam The metabolism of Alprazolam can be increased when combined with Tocilizumab.
Triazolam	Triazolam The metabolism of Triazolam can be increased when combined with Tocilizumab.
Trimethoprim	Trimethoprim The metabolism of Trimethoprim can be increased when combined with Tocilizumab.
Diltiazem	Diltiazem The metabolism of Diltiazem can be increased when combined with Tocilizumab.
Nifedipine	Nifedipine The metabolism of Nifedipine can be increased when combined with Tocilizumab.
Timolol	Timolol The metabolism of Timolol can be increased when combined with Tocilizumab.
Verapamil	Verapamil The metabolism of Verapamil can be increased when combined with Tocilizumab.
Atenolol	Atenolol The metabolism of Atenolol can be increased when combined with Tocilizumab.
Pindolol	Pindolol The metabolism of Pindolol can be increased when combined with Tocilizumab.
Cisplatin Injection	Cisplatin Injection The risk or severity of adverse effects can be increased when Cisplatin is combined with Tocilizumab.
Piroxicam	Piroxicam The metabolism of Piroxicam can be increased when combined with Tocilizumab.
Streptozocin	Streptozocin The risk or severity of adverse effects can be increased when Streptozocin is combined with Tocilizumab.
Etoposide	Etoposide The metabolism of Etoposide can be increased when combined with Tocilizumab.
Glyburide	Glyburide The metabolism of Glyburide can be increased when combined with Tocilizumab.
Glipizide	Glipizide The metabolism of Glipizide can be increased when combined with Tocilizumab.
Pentoxifylline	Pentoxifylline The metabolism of Pentoxifylline can be increased when combined with Tocilizumab.
Pentamidine Injection	Pentamidine Injection The metabolism of Pentamidine can be increased when combined with Tocilizumab.
Labetalol	Labetalol The metabolism of Labetalol can be increased when combined with Tocilizumab.
Guanabenz	Guanabenz The metabolism of Guanabenz can be increased when combined with Tocilizumab.
Pimozide	Pimozide The metabolism of Pimozide can be increased when combined with Tocilizumab.
Flurbiprofen	Flurbiprofen The metabolism of Flurbiprofen can be increased when combined with Tocilizumab.
Amiodarone	Amiodarone The metabolism of Amiodarone can be increased when combined with Tocilizumab.
Buspirone	Buspirone The metabolism of Buspirone can be increased when combined with Tocilizumab.
Lovastatin	Lovastatin The metabolism of Lovastatin can be increased when combined with Tocilizumab.
Diclofenac	Diclofenac The metabolism of Diclofenac can be increased when combined with Tocilizumab.
Fluoxetine	Fluoxetine The metabolism of Fluoxetine can be increased when combined with Tocilizumab.
Interferon Alfa-2b Injection	Interferon Alfa-2b Injection The risk or severity of adverse effects can be increased when Interferon alfa-2b is combined with Tocilizumab.
Clozapine	Clozapine The metabolism of Clozapine can be increased when combined with Tocilizumab.
Idarubicin	Idarubicin The metabolism of Idarubicin can be increased when combined with Tocilizumab.
Fludarabine Injection	Fludarabine Injection The risk or severity of adverse effects can be increased when Fludarabine is combined with Tocilizumab.
Pentostatin Injection	Pentostatin Injection The risk or severity of adverse effects can be increased when Pentostatin is combined with Tocilizumab.
Clarithromycin	Clarithromycin The metabolism of Clarithromycin can be increased when combined with Tocilizumab.
Etodolac	Etodolac The metabolism of Etodolac can be increased when combined with Tocilizumab.
Felodipine	Felodipine The metabolism of Felodipine can be increased when combined with Tocilizumab.
Nabumetone	Nabumetone The metabolism of Nabumetone can be increased when combined with Tocilizumab.
Simvastatin	Simvastatin The metabolism of Simvastatin can be increased when combined with Tocilizumab.
Amlodipine	Amlodipine The metabolism of Amlodipine can be increased when combined with Tocilizumab.
Teniposide Injection	Teniposide Injection The metabolism of Teniposide can be increased when combined with Tocilizumab.
Sotalol	Sotalol The metabolism of Sotalol can be increased when combined with Tocilizumab.
Zolpidem	Zolpidem The metabolism of Zolpidem can be increased when combined with Tocilizumab.
Doxazosin	Doxazosin The metabolism of Doxazosin can be increased when combined with Tocilizumab.
Omeprazole	Omeprazole The metabolism of Omeprazole can be increased when combined with Tocilizumab.
Cisapride	Cisapride The metabolism of Cisapride can be increased when combined with Tocilizumab.
Fluvastatin	Fluvastatin The metabolism of Fluvastatin can be increased when combined with Tocilizumab.
Venlafaxine	Venlafaxine The metabolism of Venlafaxine can be increased when combined with Tocilizumab.
Famciclovir	Famciclovir The metabolism of Famciclovir can be increased when combined with Tocilizumab.
Fluvoxamine	Fluvoxamine The metabolism of Fluvoxamine can be increased when combined with Tocilizumab.
Nefazodone	Nefazodone The metabolism of Nefazodone can be increased when combined with Tocilizumab.
Losartan	Losartan The metabolism of Losartan can be increased when combined with Tocilizumab.
Tramadol	Tramadol The metabolism of Tramadol can be increased when combined with Tocilizumab.
Vinorelbine Injection	Vinorelbine Injection The metabolism of Tocilizumab can be increased when combined with Vinorelbine.
Carboplatin Injection	Carboplatin Injection The risk or severity of adverse effects can be increased when Carboplatin is combined with Tocilizumab.
Lansoprazole	Lansoprazole The metabolism of Lansoprazole can be increased when combined with Tocilizumab.
Ifosfamide Injection	Ifosfamide Injection The metabolism of Ifosfamide can be increased when combined with Tocilizumab.
Pegaspargase Injection	Pegaspargase Injection The risk or severity of adverse effects can be increased when Pegaspargase is combined with Tocilizumab.
Nicardipine	Nicardipine The metabolism of Nicardipine can be increased when combined with Tocilizumab.
Bupropion	Bupropion The metabolism of Bupropion can be increased when combined with Tocilizumab.
Ticlopidine	Ticlopidine The metabolism of Ticlopidine can be increased when combined with Tocilizumab.
Saquinavir	Saquinavir The metabolism of Saquinavir can be increased when combined with Tocilizumab.
Nisoldipine	Nisoldipine The metabolism of Nisoldipine can be increased when combined with Tocilizumab.
Riluzole	Riluzole The metabolism of Riluzole can be increased when combined with Tocilizumab.
Glimepiride	Glimepiride The metabolism of Glimepiride can be increased when combined with Tocilizumab.
Anastrozole	Anastrozole The metabolism of Anastrozole can be increased when combined with Tocilizumab.
Gemcitabine Injection	Gemcitabine Injection The risk or severity of adverse effects can be increased when Gemcitabine is combined with Tocilizumab.
Indinavir	Indinavir The metabolism of Indinavir can be increased when combined with Tocilizumab.
Ritonavir	Ritonavir The metabolism of Ritonavir can be increased when combined with Tocilizumab.
Docetaxel Injection	Docetaxel Injection The metabolism of Docetaxel can be increased when combined with Tocilizumab.
Clomipramine	Clomipramine The metabolism of Clomipramine can be increased when combined with Tocilizumab.
Zafirlukast	Zafirlukast The metabolism of Zafirlukast can be increased when combined with Tocilizumab.
Mirtazapine	Mirtazapine The metabolism of Mirtazapine can be increased when combined with Tocilizumab.
Zileuton	Zileuton The metabolism of Zileuton can be increased when combined with Tocilizumab.
Valsartan	Valsartan The metabolism of Valsartan can be increased when combined with Tocilizumab.
Donepezil	Donepezil The metabolism of Donepezil can be increased when combined with Tocilizumab.
Azithromycin	Azithromycin The metabolism of Azithromycin can be increased when combined with Tocilizumab.
Carvedilol	Carvedilol The metabolism of Carvedilol can be increased when combined with Tocilizumab.
Flutamide	Flutamide The metabolism of Flutamide can be increased when combined with Tocilizumab.
Selegiline	Selegiline The metabolism of Selegiline can be increased when combined with Tocilizumab.
Bicalutamide	Bicalutamide The metabolism of Bicalutamide can be increased when combined with Tocilizumab.
Sertraline	Sertraline The metabolism of Sertraline can be increased when combined with Tocilizumab.
Propafenone	Propafenone The metabolism of Propafenone can be increased when combined with Tocilizumab.
Letrozole	Letrozole The metabolism of Letrozole can be increased when combined with Tocilizumab.
Irbesartan	Irbesartan The metabolism of Irbesartan can be increased when combined with Tocilizumab.
Tamsulosin	Tamsulosin The metabolism of Tamsulosin can be increased when combined with Tocilizumab.
Ropinirole	Ropinirole The metabolism of Ropinirole can be increased when combined with Tocilizumab.
Finasteride	Finasteride The metabolism of Finasteride can be increased when combined with Tocilizumab.
Quetiapine	Quetiapine The metabolism of Quetiapine can be increased when combined with Tocilizumab.
Paroxetine	Paroxetine The metabolism of Paroxetine can be increased when combined with Tocilizumab.
Palivizumab Injection	Palivizumab Injection The risk or severity of adverse effects can be increased when Palivizumab is combined with Tocilizumab.
Citalopram	Citalopram The metabolism of Citalopram can be increased when combined with Tocilizumab.
Capecitabine	Capecitabine The metabolism of Tocilizumab can be increased when combined with Capecitabine.
Efavirenz	Efavirenz The metabolism of Efavirenz can be increased when combined with Tocilizumab.
Sildenafil	Sildenafil The metabolism of Sildenafil can be increased when combined with Tocilizumab.
Pioglitazone	Pioglitazone The metabolism of Pioglitazone can be increased when combined with Tocilizumab.
Trastuzumab Injection	Trastuzumab Injection Trastuzumab may increase the neutropenic activities of Tocilizumab.
Celecoxib	Celecoxib The metabolism of Celecoxib can be increased when combined with Tocilizumab.
Rosiglitazone	Rosiglitazone The metabolism of Rosiglitazone can be increased when combined with Tocilizumab.
Tolterodine	Tolterodine The metabolism of Tolterodine can be increased when combined with Tocilizumab.
Thalidomide	Thalidomide The metabolism of Thalidomide can be increased when combined with Tocilizumab.
Nateglinide	Nateglinide The metabolism of Nateglinide can be increased when combined with Tocilizumab.
Galantamine	Galantamine The metabolism of Galantamine can be increased when combined with Tocilizumab.
Rabeprazole	Rabeprazole The metabolism of Rabeprazole can be increased when combined with Tocilizumab.
Terbinafine	Terbinafine The metabolism of Terbinafine can be increased when combined with Tocilizumab.