Avapritinib

Contraindicated

Avapritinib Bacillus Of Calmette And Guerin Vaccine, Live An increased risk of infection by the live vaccine Details Avapritinib Dengue Tetravalent Vaccine, Live An increased risk of infection by the live vaccine Details Avapritinib Ensitrelvir Increased CYP3A substrates exposure and an increased risk of CYP3A substrates-related adverse effects Details Avapritinib Levoketoconazole Recorlev Increased CYP3A4 substrate exposure and an increased risk of sensitive CYP3A4 substrate-related adverse reaction Details Avapritinib Measles Virus Vaccine, Live An increased risk of infection by the live vaccine Details Avapritinib Mumps Virus Vaccine, Live An increased risk of infection by the live vaccine Details Avapritinib Rubella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Avapritinib Smallpox Monkeypox Vaccine An increased risk of infection by the live vaccine Details Avapritinib Typhoid Vaccine Typhim VI® An increased risk of infection by the live vaccine Details Avapritinib Varicella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Avapritinib Yellow Fever Vaccine Stamaril An increased risk of infection by the live vaccine Details

Major

Avapritinib Adagrasib Krazati Increased CYP3A4 substrate exposure Details Avapritinib Adenovirus Vaccine Type 4, Live An increased risk of infection by the live vaccine Details Avapritinib Adenovirus Vaccine Type 7, Live An increased risk of infection by the live vaccine Details Avapritinib Amprenavir Increased avapritinib exposure and an increased risk of the incidence and severity of adverse reactions Details Avapritinib Apalutamide Erleada Reduced avapritinib exposure and reduced efficacy of avapritinib Details Avapritinib Aprepitant Aponvie Increased avapritinib exposure and an increased risk of the incidence and severity of adverse reactions Details Avapritinib Atazanavir Reyataz Increased avapritinib exposure and an increased risk of the incidence and severity of adverse reactions Details Avapritinib Avacopan Tavneos Increased CYP3A4 substrate exposure Details Avapritinib Berotralstat Orladeyo Increased avapritinib exposure and an increased risk of the incidence and severity of adverse reactions Details Avapritinib Boceprevir Increased avapritinib exposure and increased incidence and severity of adverse reactions Details Avapritinib Bosentan Reduced avapritinib exposure and reduced efficacy of avapritinib Details Avapritinib Carbamazepine Carbatrol Reduced avapritinib exposure and reduced efficacy of avapritinib Details Avapritinib Cenobamate Xcopri Reduced avapritinib exposure and reduced efficacy of avapritinib Details Avapritinib Ceritinib Zykadia Increased avapritinib exposure and increased incidence and severity of adverse reactions Details Avapritinib Cholera Vaccine Ipol An increased risk of infection by the live vaccine Details Avapritinib Ciprofloxacin Increased avapritinib exposure and an increased risk of the incidence and severity of adverse reactions Details Avapritinib Clarithromycin Biaxin Increased avapritinib exposure and increased incidence and severity of adverse reactions Details Avapritinib Clofazimine Increased avapritinib exposure and an increased risk of the incidence and severity of adverse reactions Details Avapritinib Cobicistat Tybost Increased avapritinib exposure and increased incidence and severity of adverse reactions Details Avapritinib Conivaptan Vaprisol Increased avapritinib exposure and an increased risk of the incidence and severity of adverse reactions Details Avapritinib Crizotinib Xalkori Increased avapritinib exposure and an increased risk of the incidence and severity of adverse reactions Details Avapritinib Dabrafenib Tafinlar Reduced sensitive CYP3A4 substrate exposure Details Avapritinib Darunavir Increased avapritinib exposure and an increased risk of the incidence and severity of adverse reactions Details Avapritinib Diltiazem Cardizem Increased avapritinib exposure and an increased risk of the incidence and severity of adverse reactions Details Avapritinib Dipyrone Reduced avapritinib exposure and reduced efficacy of avapritinib Details Avapritinib Dronedarone Multaq Increased avapritinib exposure and an increased risk of the incidence and severity of adverse reactions Details Avapritinib Duvelisib Copiktra Increased exposure of sensitive CYP3A4 substrates and risk of toxicity Details Avapritinib Ebola Zaire Vaccine, Live An increased risk of infection by the live vaccine Details Avapritinib Efavirenz Reduced avapritinib exposure and reduced efficacy of avapritinib Details