Infliximab

21 interactions 1 explained in plain English
Also sold as: Avsola Inflectra Remicade Renflexis Zymfentra
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Abatacept Injection Golimumab Injection Brodalumab Injection Anifrolumab-Fnia Injection Natalizumab Injection Cyclosporine Injection
18 Major 3 Moderate
All (21) Major (18) Moderate (3)

Major

Infliximab Abatacept Injection Orencia An increased risk of infection Details Infliximab Adalimumab Injection Abrilada Increased immunosuppression and an increased risk of infections Details Infliximab Anakinra Kineret An increased risk of serious infections Details Infliximab Anifrolumab-Fnia Injection Saphnelo Additive effects due to duplication of therapy Details Infliximab Azathioprine Azasan An increased risk of hepatotoxicity Details Infliximab Abatacept Orencia Explained An increased risk of infection Details Infliximab Baricitinib Olumiant An increased risk of infection Details Infliximab Brodalumab Injection Siliq Increased immunosuppression and an increased risk of infections Details Infliximab Certolizumab Injection Cimzia Increased immunosuppression and an increased risk of infections Details Infliximab Cyclosporine Injection Atopica Reduced cycloSPORINE exposure Details Infliximab Cyclosporine Ophthalmic Cequa Reduced cycloSPORINE exposure Details Infliximab Golimumab Injection Simponi Increased immunosuppression and an increased risk of infections Details Infliximab Guselkumab Injection Tremfya Increased immunosuppression and an increased risk of infections Details Infliximab Ixekizumab Injection Taltz Increased immunosuppression and an increased risk of infections Details Infliximab Mercaptopurine Purinethol® An increased risk of hepatotoxicity Details Infliximab Methotrexate Jylamvo Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Infliximab Methotrexate Injection Abitrexate® Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Infliximab Natalizumab Injection Tyruko Increased immunosuppression and an increased risk of infections Details

Moderate

Infliximab Dihydroergotamine Injection DHE-45® Injection Decreased dihydroergotamine plasma concentrations Details Infliximab Dihydroergotamine Nasal Spray Migranal Decreased dihydroergotamine plasma concentrations Details Infliximab Fentanyl Transdermal Patch Duragesic® Decreased fentanyl plasma concentrations Details

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