Levothyroxine Interactions
Levothyroxine is used to treat hypothyroidism (condition where the thyroid gland does not produce enough thyroid hormone). It is also used with surgery and radioactive iodine therapy to treat thyroid cancer. Levothyroxine is in a class of medications called hormones. It works by replacing thyroid hormone that is normally produced by the body.
Without thyroid hormone, your body cannot function properly, which may result in poor growth, slow speech, lack of energy, excessive tiredness, constipation, weight gain, hair loss, dry, thick skin, increased sensitivity to cold, joint and muscle pain, heavy or irregular menstrual periods, and depression. When taken correctly, levothyroxine reverses these symptoms.
Brand Names Associated with Levothyroxine
- Levo-T®
- Levothroid®
- Levothyroxine
- Levoxyl®
- Synthroid®
- Tirosint®
- Unithroid®
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- Major
- Moderate
- Aluminum Carbonate, Basic
- Aluminum Hydroxide
- Aluminum Phosphate
- Bugleweed
- Calcium Acetate
- Calcium Carbonate
- Calcium Citrate
- Calcium Polystyrene Sulfonate
- Chlorotrianisene
- Cholestyramine
- Chromium
- Ciprofloxacin
- Colesevelam
- Colestipol
- Conjugated Estrogens
- Conjugated Estrogens Synthetic A
- Conjugated Estrogens Synthetic B
- Dexlansoprazole
- Dienestrol
- Diethylstilbestrol
- Dihydroxyaluminum Aminoacetate
- Dihydroxyaluminum Sodium Carbonate
- Esterified Estrogens
- Estradiol
- Estramustine
- Estriol
- Estropipate
- Ethinyl Estradiol
- Fosphenytoin
- Imatinib
- Insulin
- Insulin Lispro, Recombinant
- Iron
- Kelp
- Lansoprazole
- Lanthanum Carbonate
- Lithospermum
- Lopinavir
- Magaldrate
- Magnesium Carbonate
- Magnesium Hydroxide
- Magnesium Oxide
- Magnesium Trisilicate
- Mestranol
- Metformin
- Omeprazole
- Orlistat
- Pantoprazole
- Patiromer
- Phenytoin
- Polyestradiol Phosphate
- Promestriene
- Quinestrol
- Rabeprazole
- Rifampin
- Ritonavir
- Sevelamer
- Simethicone
- Simvastatin
- Sodium Polystyrene Sulfonate
- Sucralfate
- Sucroferric Oxyhydroxide
- Teduglutide
- Tibolone
- Esomeprazole
- Ethinyl Estradiol; Norethindrone
- Minor
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What Do The Severity Ratings Mean?
Contraindicated
These drugs, generally, should not be used together simultaneously due to the high risk of severe adverse effects. Combining these medications can lead to dangerous health outcomes and should be strictly avoided unless otherwise instructed by your provider.
Major
This interaction could result in very serious and potentially life-threatening consequences. If you are taking this drug combination, it is very important to be under close medical supervision to minimize severe side effects and ensure your safety. It may be necessary to change a medication or dosage to prevent harm.
Moderate
This interaction has the potential to worsen your medical condition or alter the effectiveness of your treatment. It's important that you are monitored closely and you potentially may need to make adjustments in your treatment plan or drug dosage to maintain optimal health.
Minor
While this interaction is unlikely to cause significant problems, it could intensify side effects or reduce the effectiveness of one or both medications. Monitoring for changes in symptoms and your condition is recommended, and adjustments may be made if needed to manage any increased or more pronounced side effects.
Disclaimer: The information provided on this page is for informational purposes only and should not be considered medical advice. Always consult with a qualified healthcare professional regarding your specific circumstances and medical conditions.
Drug interaction information is compilated from several drug compendia, including:
- Gold Standard Drug Database
- Micromedix
- Lexicomp
- PubMed
The information posted is fact-checked by HelloPharmacist clinicians and reviewed quarterly.