Drug & supplement interaction

Body Protective Compound 157 + Apraclonidine

Apraclonidine brand name: Iopidine.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Body Protective Compound 157 and Apraclonidine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Body Protective Compound 157 and Apraclonidine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Apraclonidine and Body Protective Compound 157 in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Body Protective Compound 157 at all — not against Apraclonidine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Body Protective Compound 157 safety at a glance

Body Protective Co... overall Not established Human safety data is very limited, and quality of products sold online is often unverified.
Pregnancy Avoid No safety data exists in pregnancy, so it should be avoided.
Breastfeeding Avoid No safety data exists while breastfeeding, so it should be avoided.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Apraclonidine and Body Protective Compound 157? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Apraclonidine’s Own FDA Label Lists

This is not an interaction — none of it involves Body Protective Compound 157. These are the most notable effects listed in the ADVERSE REACTIONS section of Apraclonidine’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 7 of them are worth acting on rather than waiting out — marked below.

  • A slow heartbeat Worth acting on
  • Wheezing Worth acting on
  • An irregular heartbeat Worth acting on
  • Shortness of breath Worth acting on mentioned in 4.7% of FDA reports for Apraclonidine
  • Chest pain Worth acting on
  • Low mood Worth acting on
  • An allergic reaction Worth acting on
  • Dry eyes
  • Blurred vision mentioned in 5.7% of FDA reports for Apraclonidine
  • Dry mouth mentioned in 4.7% of FDA reports for Apraclonidine

Showing the 10 most notable of 25 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Apraclonidine. Read the label on DailyMed › Where a percentage is shown, it is the share of 106 voluntary FDA FAERS reports for Apraclonidine that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Body Protective Compound 157’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Body Protective Compound 157 side to compare — that is a limit of the record, not a statement that Body Protective Compound 157 has no side effects.

Everything else you take

See Every Supplement That Interacts With Apraclonidine

This page covers Body Protective Compound 157 only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Apraclonidine page lists 18 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Butcher's Broom (moderate), Coffee Charcoal (moderate), European Mandrake (moderate) and Glucomannan (moderate).

By severity: 1 major · 8 moderate · 9 minor.

From our pharmacist’s overview on the Apraclonidine page

“Apraclonidine (Iopidine) is an eye drop that lowers pressure inside the eye, most often around laser procedures, and its interaction list deserves a careful read rather than a shrug. Of the 18 supplement and herbal ingredients on file, only one rates major, and that one is activated charcoal, which binds many drugs and can reduce their…”

Reviewed by 2 · Jul 18, 2026

Open the Apraclonidine interaction page

How much people look this up

Where Body Protective Compound 157 and Apraclonidine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Body Protective Compound 157
Steady interest

#1,436 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Apraclonidine
Steady interest

#2,015 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Body Protective Compound 157 is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Body Protective Compound 157 reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Body Protective Compound 157 and Apraclonidine records this page draws on were last updated June 20, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Body Protective Compound 157

What is Body Protective Compound 157?

Body Protective Compound 157
  • Tendon, ligament, and muscle injuries
  • Joint pain and recovery from sports injuries
  • Gut healing and inflammation
  • Wound healing
  • General tissue repair and recovery

BPC 157 is a synthetic peptide that has shown promising healing effects in animal and laboratory studies, but it has not been proven safe or effective in well-designed human trials. It is not an approved drug or a legal dietary supplement in many places, so we cannot recommend it; talk to your doctor or pharmacist before considering it.

Synthetic peptide (a lab-made chain of 15 amino acids based on a sequence found in human gastric juice) · Injectable solution, oral capsules, nasal sprays, and topical preparations sold as research chemicals or compounded products

An interaction check asks whether these two react with each other — it does not ask whether Body Protective Compound 157 is a good idea for someone in your situation. Here is what our Body Protective Compound 157 record says about it on its own.

Body Protective Compound 157: dosing

There is no established, scientifically validated dose for BPC 157 in humans. Because it has not gone through proper clinical testing, no health authority has set a safe or effective amount.Doses suggested on websites and forums are not backed by solid human research, and we will not list specific amounts because doing so could imply they are safe or proven.

From our Body Protective Compound 157 monograph — the full record covers uses, side effects and every documented interaction.

Read the full Body Protective Compound 157 monograph & all interactions
Medication

About Apraclonidine Ophthalmic

What Is Apraclonidine Ophthalmic Used For?

Brand name: Iopidine

Apraclonidine ophthalmic solution 0.5% is indicated as a short-term add-on therapy for patients with glaucoma who are already on the maximum tolerated medical treatment but still need additional reduction in intraocular pressure (IOP — the pressure inside the eye). It may be used to help delay the need for surgery while other options are explored.

It's worth knowing that if you're already using two aqueous-suppressing drugs (medicines that reduce fluid production in the eye) — such as a beta-blocker combined with a carbonic anhydrase inhibitor — adding apraclonidine may not provide much additional benefit, since it works by the same mechanism.

Most-Reported Side Effects for Apraclonidine

From FAERS, the FDA’s public side-effect reporting system (106 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Somnolence 7 reports
Eyelid ptosis 6 reports
Vision blurred 6 reports
Constipation 5 reports
Dry mouth 5 reports
See full Apraclonidine Ophthalmic drug information
Keep checking

Other Drugs & Body Protective Compound 157

Browse every other medication we’ve checked against Body Protective Compound 157 — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Body Protective Compound 157 References

The 1 sources that drive our Body Protective Compound 157 monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Body Protective Compound 157 is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Body Protective Compound 157 and Apraclonidine Together: Common Questions

Is it safe to take Body Protective Compound 157 with Apraclonidine?
We do not list a known interaction between Body Protective Compound 157 and Apraclonidine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Apraclonidine interact with any supplements?
Yes. Apraclonidine has documented interactions with 18 supplements in our database — Body Protective Compound 157 is not one of them. The Apraclonidine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Apraclonidine and Body Protective Compound 157?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.