Dolomite - K-Phos Neutral (Dibasic Sodium Phosphate, Monobasic Potassium Phosphate, Monobasic Sodium Phosphate Monohydrate (prescription drug)) Interaction
Herbal: Dolomite
Also Known As: Calcium magnesium carbonate, Calcaire Dolomitique, Dolomita, Dolomitic Limestone, Dolostone
Drug: Dibasic Sodium Phosphate, Monobasic Potassium Phosphate, Monobasic Sodium Phosphate Monohydrate (prescription drug)
Brand names:
K-Phos Neutral
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 25, 2025
Interaction Details
Dibasic Sodium Phosphate, Monobasic Potassium Phosphate, Monobasic Sodium Phosphate Monohydrate (prescription drug) is classified as belonging to the following category: Potassium-Sparing Diuretics
Theoretically, serum magnesium levels might increase when dolomite is taken with potassium-sparing diuretics.
Potassium-sparing diuretics also have magnesium-sparing properties, which can counteract the magnesium losses associated with loop and thiazide diuretics. Dolomite contains magnesium, which may increase the risk for hypermagnesemia.
Interaction Rating
Likelihood of Occurrence
ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
References
- Ryan MP. Diuretics and potassium/magnesium depletion. Directions for treatment. Am J Med 1987;82:38-47..
- Hollifield JW. Magnesium depletion, diuretics, and arrhythmias. Am J Med 1987;82:30-7..
- Heidenreich O. Mode of action of conventional and potassium-sparing diuretics--aspects with relevance to Mg-sparing effects. Magnesium 1984;3:248-56..
Dolomite Overview
Dolomite is a mineral that is composed of calcium magnesium carbonate. It is 60% calcium carbonate and 40% magnesium carbonate. Medicinally, dolomite is used as a source of both calcium and magnesium, but its use is not recommended due to concerns it may be contaminated with heavy metals such as aluminum, arsenic, lead, mercury, and nickel.
Dolomite - More Interactions
Dolomite interacts with 127 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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