Gardenia - Psyllium Hydrophilic Mucilloid , Sennosides (OTC drug) Interaction
Herbal: Gardenia
Also Known As: Gardenia jasminoides, Cape Jasmine, Cape Jessamine, Danh Danh, E500, Fleur Jaune, Gardênia, Gardénia, Gardénia Jasminoïdes, Gardenia Yellow, Jasmin, Jasmin Do Cabo, Jasmin du Cap, Zhi Zi
Drug: Psyllium Hydrophilic Mucilloid , Sennosides (OTC drug)
Brand names:
Prompt

Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 04, 2025
Interaction Details
Psyllium Hydrophilic Mucilloid , Sennosides (OTC drug) is classified as belonging to the following category: Stimulant Laxatives
Theoretically, gardenia might increase the effects and adverse effects of stimulant laxatives.
Animal research shows that geniposide, a glucoside found in gardenia fruit, may function as a laxative and cause diarrhea when taken orally.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Yamauchi, K., Fujimoto, N., Kuwano, S., Inouye, H., and Inoue, K. The mechanism of purgative action of geniposide, an iridoid glucoside of the fruit of Gardenia, in mice. Planta Med 1976;30(1):39-47.
Gardenia Overview

Gardenia - More Interactions
Gardenia interacts with 21 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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Drug descriptions are provided by MedlinePlus.