Interaction Details

There were no interactions found between Ezetimibe and Holy Basil. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.


Still looking for more information about combining Ezetimibe and Holy Basil? Ask Dr. Brian Staiger about it by contacting him directly.

Pharmacist Analysis

While holy basil is generally considered a safe supplement with many different medications, and there is no known interaction in this case, it is important to be aware of some of its potential interactions.

Blood Thinning Drugs

  • Holy Basil may have mild blood-thinning properties.
  • Combining Holy Basil with medications like Warfarin, aspirin, or other anticoagulants/antiplatelet drugs could increase the risk of bleeding.

Blood Pressure Medications

  • Holy Basil may have mild hypotensive (blood pressure-lowering) effects.
  • Combining Holy Basil with medications used to treat high blood pressure, such as ACE inhibitors or beta-blockers, could potentially enhance the blood pressure-lowering effects.

Diabetes Medications

  • Holy Basil may have a hypoglycemic (blood sugar-lowering) effect.
  • Combining Holy Basil with diabetes medications like insulin or oral hypoglycemic drugs could potentially enhance the blood sugar-lowering effects.

Sedatives

  • Holy Basil has calming properties and may enhance the effects of sedatives or anxiety medications.
  • Combining Holy Basil with medications like benzodiazepines or sleep aids could potentially increase drowsiness or sedation.

Always talk to your healthcare provider or pharmacist before starting any new herbal supplement, including Holy Basil. They can provide personalized advice based on your specific medical history, medications, and overall health condition to ensure your safety and well-being.

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Holy Basil Overview

Holy Basil Holy basil, also known as tulsi (which in Hindi means 'the incomparable one'), is an herb often used in Ayurvedic medicine. It has small, oval-shaped leaves that are typically light green in color, with a slightly bitter/spicy flavor. Holy basil has historically been used to treat a variety of ailments, including stress, anxiety, and respiratory problems. It is also used in traditional Hindu ceremonies. It is important to note that basil and holy basil are two different varieties of herb. While they are both members of the same plant family (Lamiaceae) and are used for similar purposes, they are distinct varieties with different flavors and uses. For example, basil has a slightly sweeter flavor than holy basil.
See More Information Regarding Holy Basil

Ezetimibe Overview

  • Ezetimibe is used together with lifestyle changes (diet, weight-loss, exercise) to reduce the amount of cholesterol (a fat-like substance) and other fatty substances in the blood. It may be used alone or in combination with an HMG-CoA reductase inhibitor (statin). Ezetimibe is in a class of medications called cholesterol-lowering medications. It works by preventing the absorption of cholesterol in the intestine.

  • Buildup of cholesterol and fats along the walls of the blood vessels (a process known as atherosclerosis) decreases blood flow, which decreases the oxygen supply to the heart, brain, and other parts of the body. Lowering blood levels of cholesterol and fats may help reduce this buildup and may decrease your chances of developing heart conditions such as angina (chest pain), strokes, and heart attacks. Results of a clinical study that compared people who took ezetimibe and simvastatin with people who took simvastatin alone found that although the group of people taking ezetimibe and simvastatin had lower amounts of cholesterol in the blood, there was no difference between the two groups in the amount of cholesterol and fat buildup on the insides of the blood vessels in the neck. It is not currently understood why the additional lowering of cholesterol levels in the blood did not lead to a greater decrease in cholesterol and fat buildup along the walls of the blood vessels in people taking ezetimibe and simvastatin. Further studies are underway to compare treatment with ezetimibe and simvastatin to treatment with simvastatin alone to see if there is a difference in the risk of developing heart disease. Talk to your doctor if you have questions about the risks and benefits of treating increased amounts of cholesterol in your blood with ezetimibe and other medications.

  • In addition to taking a cholesterol-lowering medication, making certain changes in your daily habits can also lower your blood cholesterol levels. You should eat a diet that is low in saturated fat and cholesterol (see SPECIAL DIETARY); exercise 30 minutes on most, if not all, days; and lose weight if you are overweight.

See More Information Regarding Ezetimibe

Holy Basil - More Interactions

Holy Basil interacts with 209 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.

Major The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur.
Moderate Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur.
Minor Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction.
Unknown No interactions have been reported or no interaction data is currently available.

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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Drug descriptions are provided by MedlinePlus.

Ask A Pharmacist About Your Herbal Questions!

Dr. Brian Staiger, PharmD

In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!

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