Lily-of-the-valley - Ponvory (Ponesimod) Interaction
Herbal: Lily-of-the-valley
Also Known As: Convallaria majalis, Clochette des Bois, Constancy, Convallaria, Convallaria Herba, Convall-Lily, Gazon de Parnasse, Jacob's Ladder, Ladder-To-Heaven, Lily, Lirio de los Valles, Lis des Vallées, Lys des Vallées, May Bells, May Lily, Muguet, Muguet de Mai
Drug: Ponesimod
Brand names:
Ponvory
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 04, 2025
Interaction Details
There were no interactions found between Ponesimod and Lily-of-the-valley. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Lily-of-the-valley Overview
Lily of the valley (Convallaria majalis) is a small, herbaceous plant that is native to Europe and Asia and is known for its bell-shaped flowers and its red berries, which grow in the summer and fall. It is a popular ornamental plant.
Lily of the valley has been traditionally used for cardiovascular conditions but is not recommended due to safety concerns. It contains cardiac glycosides, similar to digoxin, which are extremely poisonous if used incorrectly. Lily of the valley gained popular notoriety from the television show 'Breaking Bad' in the United States as the plant used by Walter White to poison another individual.
Ponesimod Overview
-
Ponesimod is used to prevent episodes of symptoms and slow the worsening of disability in adults who have relapsing forms of multiple sclerosis (MS; a disease in which the nerves do not function properly and people may experience weakness, numbness, loss of muscle coordination, and problems with vision, speech, and bladder control), including:
-
clinically isolated syndrome (CIS; first nerve symptom episode that lasts at least 24 hours),
-
relapsing-remitting disease (course of disease where symptoms flare up from time to time),
-
active secondary progressive disease (later stage of disease with continuous worsening of symptoms.)
-
-
Ponesimod is in a class of medications called sphingosine l-phosphate receptor modulators. It works by decreasing the action of immune cells that may cause nerve damage.
Lily-of-the-valley - More Interactions
Lily-of-the-valley interacts with 157 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
Return to the main supplement interaction checker page
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
Ask A Pharmacist About Your Herbal Questions!
Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
Ask A Pharmacist