Interaction Details

There were no interactions found between Denosumab and Miracle Fruit. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.


Still looking for more information about combining Denosumab and Miracle Fruit? Ask Dr. Brian Staiger about it by contacting him directly.

Miracle Fruit Overview

Miracle Fruit Miracle fruit, also known as synsepalum dulcificum, is a small red berry native to West Africa. The active ingredient in the berry, called miraculin, temporarily alters the taste buds on the tongue, making sour and acidic foods taste sweet. Due to the effects of miraculin, it is sometimes used as a sugar substitute for people with diabetes or for those looking to reduce their sugar intake. The effects of miraculin can last for up to an hour after consumption. In addition to its use as a natural medicine, miracle berry is also commonly used as a novelty product (e.g., 'mberry miracle berry tablets'), promoted as a fun addition to parties and gatherings, where it is often used as part of a “flavor tripping” experience, where people consume sour and acidic foods, such as lemons or vinegar, and experience the change in taste sensation.
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Denosumab Overview

  • Denosumab injection (Prolia) is used

    • to treat osteoporosis (a condition in which the bones become thin and weak and break easily) in women who have undergone menopause (''change of life;'' end of menstrual periods) who have an increased risk for fractures (broken bones) or who cannot take or did not respond to other medication treatments for osteoporosis.

    • to treat men who have an increased risk for fractures (broken bones) or who cannot take or did not respond to other medication treatments for osteoporosis.

    • treat osteoporosis that is caused by corticosteroid medications in men and women who will be taking corticosteroid medications for at least 6 months and have an increased risk for fractures or who cannot take or did not respond to other medication treatments for osteoporosis.

    • to treat bone loss in men who are being treated for prostate cancer with certain medications that cause bone loss,

    • to treat bone loss in women with breast cancer who are receiving certain medications that increase their risk for fractures.

  • Denosumab injection (Xgeva) is used

    • to reduce the risk of fractures in people who have multiple myeloma (cancer that begins in the plasma cells and causes bone damage), and in people who have certain types of cancer that began in another part of the body but has spread to the bones.

    • in adults and some adolescents to treat giant cell tumor of bone (GCTB; a type of bone tumor) that cannot be treated with surgery.

    • to treat high calcium levels that are caused by cancer in people who did not respond to other medications.

    Denosumab injection is in a class of medications called RANK ligand inhibitors. It works to prevent bone loss by blocking a certain receptor in the body to decrease bone breakdown. It works to treat GCTB by blocking a certain receptor in the tumor cells which slows the tumor growth. It works to treat high calcium levels by decreasing bone breakdown as the breakdown of bones releases calcium.

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Miracle Fruit - More Interactions

Miracle Fruit interacts with 84 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.

Major The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur.
Moderate Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur.
Minor Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction.
Unknown No interactions have been reported or no interaction data is currently available.

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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Drug descriptions are provided by MedlinePlus.

Ask A Pharmacist About Your Herbal Questions!

Dr. Brian Staiger, PharmD

In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!

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