Pumpkin - Lucentis (Ranibizumab) Interaction
Herbal: Pumpkin
Also Known As: Cucurbita pepo, Calabaza, Citrouille, Cucurbitea Peponis Semen, Field Pumpkin, Graine de Citrouille, Great Pumpkin, Huile de Graines de Citrouille, Pepo, Pumpkin Seed Oil, Styrian Pumpkin
Drug: Ranibizumab
Brand names:
Lucentis, Susvimo
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jun 15, 2025
Interaction Details
There were no interactions found between Ranibizumab and Pumpkin. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Pumpkin Overview
Pumpkin is a type of squash native to North America. Pumpkin is a good source of nutrients, including vitamin A, vitamin C, potassium, and fiber. It is also a rich source of antioxidants, particularly beta-carotene, which is converted to vitamin A in the body.
Pumpkin has been used historically as a dietary supplement for supporting eye health, boosting the immune system, reducing the symptoms of benign prostatic hyperplasia, and helping to reduce the risk of certain types of cancer. Pumpkin is also a good source of fiber, which can help improve digestion and lower cholesterol levels.
Both pumpkin and pumpkin seed extracts have been utilized for dietary supplement purposes.
Ranibizumab Overview
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Ranibizumab injection products are used to treat wet age-related macular degeneration (AMD; an ongoing disease of the eye that causes loss of the ability to see straight ahead and may make it more difficult to read, drive, or perform other daily activities). Ranibizumab implant (Susvimo) is also used to treat wet age-related macular degeneration after at least two successful treatments with ranibizumab or a similar medication. Ranibizumab injection products are also used to treat myopic choroidal neovascularization (mCNV; a complication in near-sighted people where new blood vessels can grow in the back of the eye) and to treat macular edema after retinal vein occlusion (an eye disease caused by blockage of blood flow from the eye that leads to blurry vision and vision loss). Ranibizumab injection (Lucentis) is also used to treat diabetic macular edema (an eye disease caused by diabetes that can lead to vision loss) and diabetic retinopathy (damage to the eyes caused by diabetes). Ranibizumab is in a class of medications called vascular endothelial growth factor A (VEGF-A) antagonists. It works by stopping abnormal blood vessel growth and leakage in the eye(s) that may cause vision loss.
Pumpkin - More Interactions
Pumpkin interacts with 1 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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