Xanthan Gum - Metronidazole, Tetracyline, Bismuth Subcitrate Potassium Interaction
Herbal: Xanthan Gum
Also Known As: Bacterial Polysaccharide, Corn Sugar Gum, Goma Xantana, Gomme de Sucre de Maïs, Gomme de Xanthane, Gomme Xanthane, Polysaccharide Bactérien, Polysaccharide de Type Xanthane, Polysaccharide Xanthane, Xanthan
Drug: Metronidazole, Tetracyline, Bismuth Subcitrate Potassium
Brand names:
Pylera
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 11, 2025
Interaction Details
Metronidazole, Tetracyline, Bismuth Subcitrate Potassium is classified as belonging to the following category: Oral Drugs
Theoretically, xanthan gum can alter the absorption of oral drugs due to its fiber qualities. Xanthan gum slows gastric emptying and has been used to control the release of drugs in tablet formulations. To avoid any alterations in drug absorption, xanthan gum should be taken 30-60 minutes after oral medications.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Osilesi O, Trout DL, Glover EE, et al. Use of xanthan gum in dietary management of diabetes mellitus. Am J Clin Nutr 1985;42: 597-603.
- Beneke CE, Viljoen AM, Hamman JH. Polymeric plant-derived excipients in drug delivery. Molecules. 2009;14(7):2602-20.
Xanthan Gum Overview
Xanthan gum is a type of polysaccharide that is produced by the bacterium Xanthomonas campestris. It is commonly used as a food additive and is known for its ability to improve the texture and stability of foods. Medicinally, it is used as a bulk-forming laxative and a liquid thickening agent.
Metronidazole, Tetracyline, Bismuth Subcitrate Potassium Overview
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Bismuth, metronidazole, and tetracycline is used along with other ulcer medications to treat duodenal ulcers. It is in a class of medications called antibacterial agents. It works by preventing the growth and spread of Helicobacter pylori bacteria, which often occurs with ulcers. Treating this infection keeps ulcers from coming back.
Xanthan Gum - More Interactions
Xanthan Gum interacts with 1987 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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