Herb & supplement monograph

Burr Marigold Drug Interactions, Uses, Safety & More

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Interaction report

Drugs that interact with Burr Marigold

0 medications have a known interaction with Burr Marigold, graded by severity. Select any drug for the full evidence-based detail.

We don’t currently list any known drug interactions for Burr Marigold. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Burr Marigold combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Monograph

Burr Marigold: Uses, Safety & Side Effects

The bottom line

Burr Marigold (Bidens tripartita) is a wetland plant used in traditional medicine for wounds, urinary complaints, and digestive issues, but high-quality human research is lacking. Because its effectiveness and safety have not been well studied, it should be used cautiously, and avoided in pregnancy, breastfeeding, and in young children. Talk to a pharmacist or doctor before trying it.

Burr Marigold
Scientific name
Bidens tripartita
Family
Asteraceae
Part used
Above-ground parts (herb), including leaves, stems, and flowering tops
Common forms
Tea (dried herb infusion), tincture, liquid extract, dried herb
People commonly use it for
  • Minor wounds and skin irritation
  • Mild urinary complaints
  • Digestive upset
  • Coughs and colds
  • General 'cleansing' or diuretic effect

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallUse caution

Limited human safety data, so use cautiously and discuss with a healthcare professional first.

PregnancyInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full pregnancy detail
BreastfeedingInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

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Overview

Burr Marigold is a flowering plant in the daisy family (Asteraceae). The name is most often linked to Bidens tripartita, also called water agrimony or three-lobe beggarticks. A closely related plant, Bidens pilosa (often called beggarticks or sticktight), is used in similar ways in many parts of the world.

These plants grow in damp places like the edges of ponds, ditches, and marshes across Europe, Asia, and other temperate and tropical regions. They are well known for their small, barbed seeds that stick to clothing and animal fur, which is how the plant spreads.

In traditional herbal medicine, the above-ground parts of the plant have been used to make teas and extracts. People have used it for skin problems, urinary complaints, digestive issues, and minor coughs and colds.

Uses & effectiveness

Burr Marigold has a long history in folk medicine, but modern scientific evidence in humans is very limited. Most of what we know comes from laboratory studies, test-tube experiments, or animal research, which cannot tell us how well the plant works in people.

Common traditional uses include:

  • Wounds and skin irritation — applied to help with minor cuts or inflammation. Evidence is mostly traditional and laboratory-based.
  • Urinary and 'cleansing' uses — taken as a mild diuretic. This is not well proven.
  • Digestive upset — used as a bitter tonic for the stomach. Supported only by tradition.
  • Coughs and colds — used in folk remedies. Human evidence is lacking.

Laboratory studies suggest the plant may have antioxidant and antimicrobial activity, but these findings have not been confirmed by well-designed human trials. Overall, the evidence is insufficient to say that Burr Marigold is effective for any health condition.

How it works

Burr Marigold contains a mix of natural plant compounds, including flavonoids, polyacetylenes, tannins, and essential oils. Some of these compounds have shown antioxidant and germ-fighting activity in laboratory tests.

Researchers think the tannins may explain its traditional use for wounds and skin, since tannins can have a drying, astringent effect. Flavonoids may contribute to possible anti-inflammatory or antioxidant effects.

It is important to understand that these proposed mechanisms come mostly from test-tube and animal studies. They do not prove that the plant works the same way, or at all, when used by people.

Safety & precautions

There is not enough reliable human research to know how safe Burr Marigold is, especially with regular or long-term use. Because of this, it should be used cautiously.

People who are allergic to plants in the daisy (Asteraceae) family — such as ragweed, marigolds, daisies, and chrysanthemums — may be more likely to have an allergic reaction.

Pregnancy and breastfeeding: There is no good safety data, so it is best to avoid Burr Marigold if you are pregnant, trying to become pregnant, or breastfeeding.

It is also best to avoid giving it to infants and young children. People with kidney problems should be especially careful, since the plant is sometimes used as a diuretic. Always talk to a pharmacist or doctor before starting any new herbal product.

Side effects

Because Burr Marigold has not been carefully studied in people, its full side effect profile is unknown. Possible side effects, based on its plant family and general herbal use, may include:

  • Allergic reactions, especially in people sensitive to daisy-family plants, ranging from skin rash to more serious reactions.
  • Stomach upset or digestive discomfort.
  • Skin irritation when applied directly to the skin.

Stop using it and seek medical care if you notice signs of a serious allergic reaction, such as swelling of the face, lips, or throat, or trouble breathing.

Dosing

There is no established standard dose for Burr Marigold. Traditional use has involved teas made from the dried herb, as well as tinctures and liquid extracts, but reliable dosing guidelines from clinical research do not exist.

If you choose to use a commercial product, follow the directions on the label and do not exceed the recommended amount. Because product strength and quality can vary a lot between brands, it is wise to check with a pharmacist or doctor first, especially if you take other medicines or have a health condition.

Pregnancy & Breastfeeding

Burr Marigold & Pregnancy

Insufficient reliable information

Insufficient reliable information available; avoid using.

Burr Marigold & Breastfeeding

Insufficient reliable information

Insufficient reliable information available; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 2 sources that drive our Burr Marigold monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing.

  1. MedlinePlus: Herbal Medicine — MedlinePlus (NIH) Source
  2. Using Dietary Supplements Wisely — NIH NCCIH Source
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Pharmacist Counseling Corner

Burr Marigold: Common Questions

Does Burr Marigold interact with prescription medications?
We do not currently list any known drug interactions for Burr Marigold. This does not guarantee that none exist, so always confirm with your pharmacist before combining it with your medications.
How are Burr Marigold interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Burr Marigold with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Burr Marigold interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
What is Burr Marigold used for?
It is used in traditional medicine for minor wounds, skin irritation, mild urinary complaints, digestive upset, and coughs and colds. However, there is little high-quality human evidence to confirm it works for any of these.
Is Burr Marigold safe to take?
Its safety has not been well studied in people. Use it cautiously, avoid it if you are allergic to daisy-family plants, and check with a pharmacist or doctor before trying it.
Can I use Burr Marigold during pregnancy or while breastfeeding?
No reliable safety information is available, so it is best to avoid Burr Marigold if you are pregnant or breastfeeding.
How is Burr Marigold usually taken?
It is most often taken as a tea made from the dried herb, or as a tincture or liquid extract. Because there is no standard dose, follow the product label and ask a healthcare professional for guidance.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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