Scotch Thistle Interactions Overview
Check For Interactions With Scotch Thistle
Scotch Thistle
- Onopordum acanthium
- Acanthe Sauvage
- Alcachofa Borriquera
- Ansarina
- Cardo Borriquero
- Chardon aux Ânes
- Chardon d'Écosse
- Chardon à Feuilles d'Acanthe
- Herbe aux Ânes
- Onoporde Acanthe
- Onopordon Fausse-Acanthe
- Toba
- Woolly Thistle

Additional Details
Is Scotch Thistle Safe? Are There Any Warnings?
Scotch thistle, scientifically known as Onopordum acanthium, is a distinctive variety of thistle plant distinguished by its spiny leaves. Native to certain regions of Asia and Europe, it has also managed to establish its presence in areas across North America, South America, and Australia. Despite its intriguing potential for various applications, a clear and definitive assessment of its safety profile remains elusive due to a paucity of substantial data.
For individuals who are pregnant or breastfeeding, it is prudent to exercise caution and abstain from using Scotch thistle, as reliable information regarding its effects during these critical periods is currently insufficient.
How Is Scotch Thistle Used and What Is It Known For?
Scotch thistle, an imposing botanical specimen, has historically been employed as a cardiac stimulant. Its spectrum of applications extends to addressing various conditions such as cancer, ulcers, fever, and urogenital diseases. However, the substantiated effectiveness of these applications remains pending further meticulous scientific investigation.
What Is Its Safety Profile?
The comprehensive safety profile of Scotch thistle is not firmly established due to the limited availability of substantiated data. While no reported adverse effects are on record, it's important to acknowledge that a comprehensive safety evaluation has yet to be conducted to conclusively ascertain potential risks associated with its use.
How Does Scotch Thistle Work? What Is the Mechanism of Action?
Delving into the mechanisms underlying the effects of Scotch thistle unveils a complex interplay of constituents found within its aerial parts. This array of components encompasses flavonoids, phenolic acids, lignans, sterols, sesquiterpenoids, and triterpenoids.
The historical use of Scotch thistle as an antibacterial agent aligns with the presence of sesquiterpene lactones, particularly a compound known as onopordopicrin. This compound demonstrates antibacterial effects in vitro, highlighting its potential antimicrobial properties.
Furthermore, insights gleaned from in vitro studies suggest that scotch thistle extract possesses anti-inflammatory properties. This anti-inflammatory activity is attributed to its capacity to inhibit the expression and activity of cyclooxygenase-2 (COX-2) as well as the production of nitric oxide. Active constituents including lignans, flavonoids, and sesquiterpenes contribute to these effects.
Pharmacokinetics
Regrettably, comprehensive information concerning the pharmacokinetics of Scotch thistle remains notably limited. A thorough exploration into aspects such as its absorption, distribution, metabolism, and excretion within human physiological systems is a crucial area that requires dedicated investigation.
Interaction Overview
At present, no documented interactions involving Scotch thistle with pharmaceutical agents or dietary supplements have been substantiated. However, a judicious approach involves seeking consultation with a healthcare professional before incorporating Scotch thistle into existing therapeutic regimens, considering the current dearth of comprehensive interaction data.
Common Side Effects To Watch For
Preliminary information suggests that adverse reactions following the oral administration of Scotch thistle are infrequent. Nevertheless, it is pertinent to acknowledge the absence of a comprehensive safety evaluation. If anomalous reactions or discomfort manifest subsequent to the use of Scotch thistle, seeking medical attention is a prudent course of action.
Are Supplements Standardized?
Information regarding the standardization of supplements containing Scotch thistle is currently lacking. The practice of standardization involves ensuring consistent levels of active constituents in each supplement dose. In light of the absence of comprehensive standardization information, prudent discretion is advised when selecting and utilizing such products.
What Is Scotch Thistle Typically Used For?
Scotch thistle finds its historical employment in a diverse array of health-related applications, encompassing the amelioration of cardiac function as well as addressing conditions such as cancer, ulcers, fever, and urogenital diseases. However, the verifiable effectiveness of these applications awaits further substantiation through rigorous scientific scrutiny.
Drugs that interact with Scotch Thistle
Return to the main supplement interaction checker page
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLCs