Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

B12 B6 & Folate Cherry Ingredients & Drug Interactions

by Hallelujah Diet

B12 B6 & Folate Cherry label
See full label image
Tablet Or Pill Category: Vitamin
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking B12 B6 & Folate Cherry against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

B12 B6 & Folate Cherry is a dietary supplement by Hallelujah Diet with 3 active ingredients. Its ingredients are commonly taken for treating or preventing b12 deficiency, pernicious anemia, low energy and fatigue.Based on those ingredients, 230 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin B-6, Vitamin B12. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against B12 B6 & Folate Cherry by Hallelujah Diet

Ask about any prescription or over-the-counter medication and we check it for interactions with B12 B6 & Folate Cherry by Hallelujah Diet — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of B12 B6 & Folate Cherry by Hallelujah Diet

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains three active B vitamins. Vitamin B12 supports energy and nerve health and is used to treat B12 deficiency.

Vitamin B6 (pyridoxine) plays a role in brain development and immune function. Folate (also called folic acid) is essential for cell division and DNA synthesis.

The remaining ingredients are inactive—fillers and binders like mannitol, croscarmellose sodium, and magnesium stearate that help form the tablet, plus natural cherry flavor.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Energy, fatigue, depression, anemia support.
  • We looked for evidence on: Fatigue, Depression, Dementia, Peripheral neuropathy, Chemotherapy-induced peripheral neuropathy, Diabetic neuropathy — and 4 related terms.
  • The strongest evidence on file: Vitamin B6 is rated "Possibly Effective" for Premenstrual syndrome (PMS) (Natural Medicines).
  • Also on file: Vitamin B6 is rated "Possibly Ineffective" for Carpal tunnel syndrome.
  • Also on file: Vitamin B12 is rated "Insufficient Reliable Evidence To Rate" for Chemotherapy-induced peripheral neuropathy, Dementia, Depression, Diabetic neuropathy, and more.

Vitamin B12 is effective for treating B12 deficiency and a rare condition called Imerslund-Grasbeck disease, and is likely effective for cyanide poisoning. It's possibly effective for canker sores and a nerve pain condition called postherpetic neuralgia.

Vitamin B6 is effective for sideroblastic anemia and B6 deficiency, and likely effective for a condition called hyperhomocysteinemia. It's possibly effective for pregnancy-related nausea and vomiting.

We hold no effectiveness data for folate in this product.

The evidence, ingredient by ingredient Vitamin B12 Vitamin B6

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both B12 and B6 are generally well tolerated when taken by mouth. B12 is very safe—excess is cleared through the urine, and there's no established upper limit.

It's considered safe in pregnancy and while breastfeeding at normal recommended amounts. B6 is safe at normal dietary amounts and standard supplement doses, but high doses taken over a long time can damage nerves (a condition called sensory neuropathy).

High-dose B6 over extended periods poses the greatest risk, though nerve damage can happen even at lower doses in some cases. If you're pregnant, check with your provider before use, as the safety data shows B6 as possibly unsafe in pregnancy despite also being listed as likely safe at recommended amounts—your doctor's guidance matters here.

Rare allergic reactions like rash or itching can occur with B12, and some people have developed contact dermatitis, possibly linked to cobalt in the B12 molecule.

Side effects, ingredient by ingredient Vitamin B12 Vitamin B6

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Vitamin B12, Vitamin B6.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: Parkinson's medications.
  • For scale: 230 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take metformin, antihypertensive drugs, amiodarone, phenobarbital, phenytoin, or levodopa without carbidopa, check with your pharmacist first. The vitamin B6 in this product can have moderate effects on blood pressure medications, heart rhythm drugs, and seizure medications at higher doses, and a minor effect on Parkinson's medication.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a straightforward B-vitamin combination well suited for people with B12 or B6 deficiency or those at risk of low levels. If you take metformin for diabetes, blood pressure drugs, heart rhythm medications, or seizure medications, talk to your pharmacist before starting—the interactions are manageable with the right timing and monitoring.

Pregnant women should check with their doctor before use.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 24, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about B12 B6 & Folate Cherry, straight from the product label.

Brand Hallelujah Diet
Net contents 60 Sublingual Tablet(s)
Market status On market
Date entered into DSLD Mar 24, 2017
DSLD ID 71511
Product type Vitamin
Supplement form Tablet Or Pill
Dietary claims / uses Nutrient, All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for B12 B6 & Folate Cherry by Hallelujah Diet, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Sublingual Tablet(s)
Maximum serving Sizes:
1 Sublingual Tablet(s)
Servings per container
60
IngredientAmount% DV
Folate400 mcg--
Vitamin B121000 mcg--
Vitamin B-625 mg--

Other ingredients: Mannitol, Fructose, Croscarmellose Sodium, natural Cherry flavor, Silicon Dioxide, Magnesium Stearate, Stearic Acid

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Copyright 2015 Hallelujah Diet. All right reserved.

Further research conducted by Hallelujah Diet Research Director Dr. Michael Donaldson revealed low levels of B12 in 47% of the 54 test subjects.

All Hallelujah Diet supplements and snack foods pass our rigorous high standards. We don't sell anything that we wouldn't use ourselves.

General Statements

Feeling tired and run down? Depressed? You’re not alone. Many people lack sufficient B12 in their blood. Our sublingual (can dissolve under the tongue for best results), bio-active B12, B6 and folate: ~ Play a vital role in energizing the body, and cleaning and nourishing the body by removing harmful toxins ~ Deliver excellent support for better mood ~ Fight fatigue and improve nerve health ~ Provide a potent antioxidant to help prevent harmful oxidation of cells ~ Reduces oxidative stress that can lead to chronic inflammation ~ Prevents lipid peroxidation and cell damage

Description Vitamin B12 is often overlooked as a key, missing factor when the body is dealing with fatigue, anemia, depression and developmental delay issues in children and dementia. The best way to rule out the possibility of a B12 deficiency (and to prevent one) is to use a sublingual, bio-active B12 supplement, formulated along with co-factors B6 and folate, also in their bio-active forms. Because B12, B6 and Folate play such a vital role in energy production and detoxification, results from one bottle will usually reveal whether you need more B12.

Vegans and vegetarians are typically low in vitamin B12 because it is not found in plant foods. However, people who eat meat are often low in B12 as well. An article in the American Journal of Clinical Nutrition in 2000 revealed that 39% of individuals tested had low-to-normal levels of B12 in their blood, and 17% had levels low enough to cause symptoms of deficiency. The most reliable source of B12 for people in this study was supplemental B12 from breakfast cereal. As we age, most of us do not absorb B12 efficiently from animal source foods, so supplements become the best source of dietary B12.

Thus, it became clear that it is wise for everyone to be aware of their need for B12, regardless of their diet. And for those following a vegan or vegetarian diet, including The Hallelujah Diet, it is vital to use a B12 supplement, preferably one formulated with methylcobalamin, the active form of B12, not cyanocobalamin, which the body must convert before it can be used.

Additional benefits are as follows… Health benefits of vitamin B12 ~ Vitamin B12 is especially important for rapidly dividing cells (like blood cells, skin, lining of digestive tract, and more) ~ Vitamin B12 helps the liver detoxify effectively by supporting the Methylation (Methyl) Cycle’s production of glutathione ~ The Methyl Cycle also helps your body produce melatonin, dopamine, serotonin and other molecules important to mood and energy levels Health benefits of vitamin B6 ~ Vitamin B6 is important for recycling homocysteine for production of glutathione (part of the Methyl Cycle) Health benefits of folate ~ Folate is important for production of DNA ~ Folate is critical for optimization of the Methyl Cycle ~ For pregnant women or women who hope to become pregnant, folate plays a role in the healthy development of the baby in your womb For more information on B12 and misdiagnosed health issues, see the book: Could It Be B12?. You can also read more about the vitamin on the National Institute of Health, Office of Dietary Supplements website here.

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Formula

Vitamins B12 and B6 and folate are all critical elements of the methyl cycle, and work best in their activated forms as provided in the Hallelujah Diet B12, B6 and folate supplement.

Suggested/Recommended/Usage/Directions

Suggested Use: 1 sublingual tablet daily or as directed by a healthcare professional. For best results, dissolve under the tongue.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

B12 B6 & Folate Cherry by Hallelujah Diet label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

B12 B6 & Folate Cherry label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in B12 B6 & Folate Cherry by Hallelujah Diet

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Sublingual Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Folate

400 mcg per serving

Vitamin B12

Interacts with
20 drugs
1000 mcg per serving Form: Methylcobalamin

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very h...

Vitamin B12 monograph & interactions

Vitamin B-6

Interacts with
210 drugs
25 mg per serving Form: Pyridoxal 5-Phosphate

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is b...

Vitamin B-6 monograph & interactions

Other (inactive) ingredients: Mannitol, Fructose, Croscarmellose Sodium, Natural Cherry flavor, Silicon Dioxide, Magnesium Stearate, Stearic Acid. These complete the product’s ingredient list but are not active constituents.

Interaction report

B12 B6 & Folate Cherry by Hallelujah Diet Drug Interactions

Want to check YOUR meds against B12 B6 & Folate Cherry?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
230Drugs
205 Moderate 25 Minor

Ingredients driving the most interactions

Vitamin B-6 210
Vitamin B12 20

Individual Drug Interactions

The ingredients in B12 B6 & Folate Cherry interact with 230 drugs. Click any drug to see the details.

2 of the 3 ingredients in B12 B6 & Folate Cherry interact with drugs. Each result below shows which ingredient is responsible. Vitamin B-6 Vitamin B12

Each ingredient & the kinds of drugs it affects

For each ingredient in B12 B6 & Folate Cherry with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin B-65 drug types · 210 drugs

Amiodarone (Cordarone)

Theoretically, vitamin B6 might increase the photosensitivity caused by amiodarone.
Despite initial case reports suggesting that pyridoxine may have a protective effect against amiodarone-induced photosensitivity, preliminary clinical research suggests that pyridoxine may actually exacerbate this adverse effect.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Research in hypertensive rats shows that vitamin B6 can decrease systolic blood pressure. Similarly, clinical research in patients with hypertension shows that taking high doses of vitamin B6 may reduce systolic and diastolic blood pressure, possibly by reducing plasma levels of epinephrine and norepinephrine.

Likelihood Possible Evidence B
Phenobarbital (Luminal)

High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenobarbital, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenobarbital to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

High doses of vitamin B6 may reduce the levels and clinical effects of phenytoin.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenytoin, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenytoin to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Levodopa

Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Vitamin B6 (pyridoxine) enhances the metabolism of levodopa, reducing its clinical effects. However, this interaction does not occur when carbidopa is used concurrently with levodopa (Sinemet). Therefore, it is not likely to be a problem in most people.

Likelihood Unlikely Evidence D
Vitamin B-6 full monograph & interactions

Vitamin B121 drug type · 20 drugs

Metformin (Glucophage)

Metformin, a common medication used to manage type 2 diabetes, has been associated with lower vitamin B12 levels in some individuals. Prolonged use of metformin can interfere with the absorption of B12 in the digestive system, potentially leading to a deficiency in this essential vitamin.

Likelihood Possible Evidence A
Vitamin B12 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for B12 B6 & Folate Cherry, from the product label.

Hallelujah Diet

See all Hallelujah Diet products
Street Address
916 Cox Road, Suite 210
City
Gastonia
State
NC
ZipCode
28054
Phone Number
800-915-9355
Pharmacist Counseling Corner

B12 B6 & Folate Cherry by Hallelujah Diet: Common Questions

Does B12 B6 & Folate Cherry by Hallelujah Diet interact with any medications?
Yes. Based on its ingredients, B12 B6 & Folate Cherry has a known interaction with 230 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
B12 B6 & Folate Cherry contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my energy?
B12 supports energy and overall metabolism, so if you're deficient in B12, supplementing it should help. If your energy is normal and your B12 levels are adequate, this product won't give you an extra boost. A simple blood test can tell you where you stand.
Can I take this if I'm pregnant?
B12 is considered safe in pregnancy at recommended amounts and is actually needed. B6 is listed as both likely safe and possibly unsafe in pregnancy, so you'll want to talk with your doctor or midwife before starting—they can give you personalized advice based on your situation. We don't have safety data on file for folate in this product.
What if I take it and get a rash or itching?
Allergic reactions to B12 are rare but can happen, sometimes in people with a cobalt allergy. If you develop a rash, itching, or any skin reaction, stop taking it and talk with your pharmacist or doctor right away.
Is this safe for people on seizure medications?
At the doses typically found in a standard supplement like this, probably yes—but at high doses (200 mg daily or more), B6 can reduce how well phenobarbital and phenytoin work. That's why it's important to check with your pharmacist before starting if you take either of those medications.
Why can't you tell me about folate interactions?
We don't hold monograph data for folate, so we can't check what it might interact with. If you have questions about folate specifically, your pharmacist can look that up for you or recommend a reference.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if B12 B6 & Folate Cherry is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

B12 B6 & Folate Cherry label
Go deeper

The Full Monographs Behind B12 B6 & Folate Cherry’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin B12

Interacts with 20 drugs

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very helpful for people who are deficient — su...

Read the full Vitamin B12 monograph → Herb & supplement monograph

Vitamin B6

Interacts with 210 drugs

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is best known for helping with pregnancy-rel...

Read the full Vitamin B6 monograph →
Sources

Sources & How We Checked

B12 B6 & Folate Cherry's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 62 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin B12 30 references
  1. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  2. Hartman TJ, Woodson K, Stolzenberg-Solomon R, et al. Association of the B-vitamins pyridoxal 5'-phosphate (B6), B12, and folate with lung cancer risk in older men. Am J Epidemiol 2001;153:688-94.. DOI
  3. Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
  4. Lange H, Suryapranata H, De Luca G, et al. Folate therapy and in-stent restenosis after coronary stenting. N Engl J Med 2004;350:2673-81. PubMed
  5. Collin, S. M., Metcalfe, C., Refsum, H., Lewis, S. J., Zuccolo, L., Smith, G. D., Chen, L., Harris, R., Davis, M., Marsden, G., Johnston, C., Lane, J. A., Ebbing, M., Bonaa, K. H., Nygard, O., Ueland, P. M., Grau, M. V., Baron, J. A., Donovan, J. L., Nea
  6. Geissbuhler, P., Mermillod, B., and Rapin, C. H. Elevated serum vitamin B12 levels associated with CRP as a predictive factor of mortality in palliative care cancer patients: a prospective study over five years. J.Pain Symptom.Manage. 2000;20(2):93-103. PubMed
  7. Salles, N., Herrmann, F., Sakbani, K., Rapin, C. H., and Sieber, C. High vitamin B12 level: a strong predictor of mortality in elderly inpatients. J Am Geriatr.Soc 2005;53(5):917-918.
  8. Looker, H. C., Fagot-Campagna, A., Gunter, E. W., Pfeiffer, C. M., Sievers, M. L., Bennett, P. H., Nelson, R. G., Hanson, R. L., and Knowler, W. C. Homocysteine and vitamin B(12) concentrations and mortality rates in type 2 diabetes. Diabetes Metab Res R
  9. Uhl, W., Nolting, A., Golor, G., Rost, K. L., and Kovar, A. Safety of hydroxocobalamin in healthy volunteers in a randomized, placebo-controlled study. Clin Toxicol (Phila) 2006;44 Suppl 1:17-28. PubMed
  10. Borron, S. W., Baud, F. J., Barriot, P., Imbert, M., and Bismuth, C. Prospective study of hydroxocobalamin for acute cyanide poisoning in smoke inhalation. Ann Emerg.Med 2007;49(6):794-801, 801. PubMed
  11. Borron, S. W., Baud, F. J., Megarbane, B., and Bismuth, C. Hydroxocobalamin for severe acute cyanide poisoning by ingestion or inhalation. Am J Emerg.Med 2007;25(5):551-558. PubMed
  12. Lewis, J. G. Gout, Steatorrhoea, and Megaloblastic Anaemia. Ann Rheum.Dis 1962;21(3):284-286. PubMed
  13. Tal, S., Shavit, Y., Stern, F., and Malnick, S. Association between vitamin B12 levels and mortality in hospitalized older adults. J Am Geriatr.Soc 2010;58(3):523-526. PubMed
  14. Baztan, J. J., Gavidia, J. J., Gomez-Pavon, J., Esteve, A., and Ruiperez, I. High vitamin B12 levels and in-hospital mortality. J Am Geriatr.Soc 2010;58(11):2237-2238. PubMed
  15. Omboni, E., Checchini, M., and Longoni, F. [Hypopotassemia and megaloblastic anemia. Presentation of a case]. Minerva Med 8-31-1987;78(16):1255-1257.
  16. Aalfs As, Scholvinck LH, Horvath B. Acneiform eruption in a 5-year old due to vitamin B12 supplementation. Eur J Dermatol 2013;23(5):726-7. PubMed
  17. Balta I, Ozuguz P. Vitamin B12-induced acneiform eruption. Cutan Ocul Toxicol 2014;33(2):94-5. PubMed
  18. Carman KB, Belgemen T, Yis U. Involuntary movements misdiagnosed as seizure during vitamin B12 treatment. Pediatr Emerg Care 2013;29(11):1223-4. PubMed
  19. Djuric V, Bogic M, Popadic AP, et al. Anaphylactic reaction to hydroxycobalamin with tolerance to cyanocobalamin. Ann Allergy Asthma Immunol 2012;108(3):207-8. PubMed
  20. Kartel O, Gulec M, Demirel F, et al. Vitamin B12 allergy and successful desensitization with cyanocobalamin: A case report. Allergol Immunopath (Madr) 2012;40(5):324-5.
  21. Patiroglu T, Unal E, Yildirim S. Infantile tremor syndrome associated with cobalamin therapy: A case report. Clin Neurol Neurosurg 2013;115(9):1903-5. PubMed
  22. Schulte S, Barkema LW, Kardaun SH. Long-lasting atypical acneiform eruption with prominent comedones induced by hydroxocobalamin (vitamin B12). J Dtsch Dermatol Ges 2014;12(6):502-3.
  23. Zanus C, Alberini E, Costa P, et al. Involuntary movements after correction of vitamin B12 deficiency: A video-case report. Epileptic Disord 2012;14(2):174-80. PubMed
  24. Fanidi A, Carreras-Torres R, Larose TL, et al. Is high vitamin B12 status a cause of lung cancer? Int J Cancer. 2019 Sep 15;145(6):1499-1503. PubMed
  25. Fujita Y, Mizukami T, Maya Y, et al. Vitamin B12 allergy manifesting as lymphomatoid contact dermatitis. Eur J Dermatol. 2020;30(3):304-305. PubMed
  26. Dépret F, Hoffmann C, Daoud L, et al. Association between hydroxocobalamin administration and acute kidney injury after smoke inhalation: a multicenter retrospective study. Crit Care. 2019;23(1):421. PubMed
  27. Khairan P, Sobue T, Eshak ES, et al. Association of dietary intakes of vitamin B12, vitamin B6, folate, and methionine with the risk of esophageal cancer: the Japan Public Health Center-based (JPHC) prospective study. BMC Cancer 2021;21(1):982. PubMed
  28. Evans J, Pandya A, Ding Y, Qunibi WY. Hydroxocobalamin-Induced Oxalate Nephropathy in a Patient With Smoke Inhalation. Kidney Int Rep 2021;6(8):2228-2231. PubMed
  29. Lacombe V, Chabrun F, Lacout C, et al. Persistent elevation of plasma vitamin B12 is strongly associated with solid cancer. Sci Rep 2021;11(1):13361. PubMed
  30. Pegalajar-García MD, Cebolla-Verdugo M, Prados-Carmona Á, Llamas-Segura C, Navarro-Triviño FJ. Systemic allergic dermatitis to cobalt present in cyanocobalamin supplementation. Contact Dermatitis 2023;89(3):203-205. PubMed

See these in context on the Vitamin B12 monograph →

Vitamin B6 32 references
  1. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Geerling BJ, Dagnelie PC, Badart-Smook A, et al. Diet as a risk factor for the development of ulcerative colitis. Am J Gastroenterol 2000;95:1008-13. PubMed
  4. South M. Neonatal seizures after pyridoxine use -- reply. Lancet 1999;354:2083. PubMed
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  6. Baxter P, Aicardi J. Neonatal seizures after pyridoxine use. Lancet 1999;354:2082-3. PubMed
  7. Bendich A, Cohen M. Vitamin B6 safety issues. Ann N Y Acad Sci 1990;585:321-30.
  8. Schaumburg H, Kaplan J, Windebank A. Sensory neuropathy from pyridoxine abuse. A new megavitamin syndrome. N Engl J Med 1983;309:445-8. PubMed
  9. Gordon N. Pyridoxine dependency: an update. Dev Med Child Neurol 1997;39:63-5. PubMed
  10. Lewis PJ. Pain in the hand and wrist. Pyridoxine supplements may help patients with carpal tunnel syndrome. BMJ 1995;310:1534. PubMed
  11. Kaufman G. Pyridoxine against amiodarone-induced photosensitivity (letter). Lancet 1984;1:51-2. PubMed
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See these in context on the Vitamin B6 monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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