No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Benfotiamine 300 mg Ingredients & Drug Interactions

by NusaPure

Capsule Category: Vitamin
No known interaction
The interaction bottom line No known interaction

Benfotiamine 300 mg is a dietary supplement by NusaPure with 1 active ingredient. Its ingredients are commonly taken for diabetic nerve pain (neuropathy), supporting healthy nerve function, thiamine deficiency.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Benfotiamine 300 mg by NusaPure

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: benfotiamine, a fat-soluble form of thiamine (vitamin B1). The capsule also contains inactive ingredients — cellulose, rice flour, silica, and magnesium stearate — which serve as fillers and binders.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Benfotiamine's overall clinical evidence instead.

Moderate

Some clinical evidence supports Benfotiamine for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Diabetic neuropathy — rated "Possibly Effective" (Natural Medicines).

Benfotiamine is possibly effective for diabetic neuropathy (nerve pain related to diabetes). For diabetic kidney disease (diabetic nephropathy), the evidence suggests it's probably not effective.

The evidence for alcohol use disorder, Alzheimer disease, and general nerve pain (peripheral neuropathy) is too limited or unreliable to say whether it works.

The evidence, ingredient by ingredient Benfotiamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Benfotiamine is generally well tolerated in studies, though long-term safety data is limited. In one 6-week trial, a small number of participants reported allergic skin reactions and mild stomach discomfort, at rates no different from placebo.

Safety during pregnancy hasn't been adequately studied — there isn't enough data to know whether it's safe, so talk with your doctor or pharmacist for personalized guidance. The same goes for breastfeeding: caution is advised because safety data is sparse.

Side effects, ingredient by ingredient Benfotiamine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for benfotiamine. Still, mention this supplement to your doctor or pharmacist so they can flag any concerns specific to your medications and health.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

If you're dealing with diabetic nerve pain, this might be worth discussing with your doctor — the evidence leans toward possibly helpful. For other uses listed here, the evidence is either weak or missing.

Talk with your doctor or pharmacist about whether benfotiamine fits your situation and whether it makes sense alongside anything else you're taking.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Benfotiamine 300 mg, straight from the product label.

Brand NusaPure
Barcode (UPC) X001HVMPI7
Net contents 180 Veg Cap(s)
Market status On market
Date entered into DSLD Feb 22, 2024
DSLD ID 307280
Product type Vitamin
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Benfotiamine 300 mg by NusaPure, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veggie Capsule(s)
Maximum serving Sizes:
1 Veggie Capsule(s)
Servings per container
180
UPC/BARCODE
X001HVMPI7
IngredientAmount% DV
Benfotiamine300 mg--

Other ingredients: Cellulose, Rice Flour, Silica, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: For adults, take one (1) capsule daily, preferably with meals.

Precautions

Warning: Do not exceed recommended dose. Do not use if either tamper-evident seal is broken or missing.

If you are pregnant, may become pregnant, or breastfeeding, consult your health care professional before using this product.

Keep out of reach of children.

Allergen information: Not manufactured with yeast, wheat, gluten, soy, corn, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Formulation

Natural color variation may occur in this product.

GMO free Made with Non-GMO ingredients Gluten free FDA Registered Facility

Assembled in USA Tested Supports normal nutritional supplementation Made under strict GMP guidelines Max strength

Suitable for vegetarians/vegans

Allergen information: Not manufactured with yeast, wheat, gluten, soy, corn, milk, egg, fish, shellfish or tree nut ingredients.

Storage

Store in cool dry place. Avoid excessive heat or moisture.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Premium quality Assembled in USA

cGMP Manufactured in a cGMP Inspected Facility

FDA Statement of Identity

Dietary Supplement

See for yourself

Benfotiamine 300 mg by NusaPure label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Benfotiamine 300 mg by NusaPure

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Veggie Capsule(s) Dosage formCapsule Servings per container180 Amounts shown are per serving.

Benfotiamine

No known
interactions
300 mg per serving

Benfotiamine is a man-made, fat-soluble form of vitamin B1 (thiamine) that the body may absorb more easily than regular thiamine. It is mostly studied...

Benfotiamine monograph & interactions

Other (inactive) ingredients: Cellulose, Rice Flour, Silica, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Benfotiamine 300 mg by NusaPure Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Benfotiamine 300 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Benfotiamine 300 mg, from the product label.

NusaPure

See all NusaPure products
Name
Gmax Central, LLC
Street Address
500 Westover Dr. #92909
City
Sanford
State
NC
ZipCode
27330
Pharmacist Counseling Corner

Benfotiamine 300 mg by NusaPure: Common Questions

Does Benfotiamine 300 mg by NusaPure interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Benfotiamine 300 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Benfotiamine 300 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does benfotiamine actually work for diabetic nerve pain?
The evidence suggests it's possibly effective for that. It's one of the clearer uses we have data for, though it's not a guarantee it'll work for you — talk with your doctor about whether to try it.
What side effects should I watch for?
In a clinical trial, a small number of people reported allergic skin reactions or mild stomach upset, but these showed up at the same rate in the placebo group. Most people tolerate it well.
Is it safe to take if I'm pregnant?
There isn't enough safety data during pregnancy to say either way. Talk with your doctor or pharmacist — they can weigh the risks and benefits for your situation.
Can I take this while breastfeeding?
Safety during breastfeeding hasn't been well studied. Caution is advised. Check with your doctor or pharmacist before starting, since they know your full health picture.
What is benfotiamine exactly?
It's a fat-soluble form of thiamine, a B vitamin. Because it dissolves in fat, your body can absorb and use it differently than regular thiamine.
Does it interact with any medications?
No interactions are documented for benfotiamine in our data. That doesn't guarantee none exist, so mention it to your doctor or pharmacist when you talk about your other medicines.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Benfotiamine 300 mg label
Go deeper

The Full Monographs Behind Benfotiamine 300 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Benfotiamine 300 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Benfotiamine 1 reference
  1. Stracke H, Gaus W, Achenbach U, Federlin K, Bretzel RG. Benfotiamine in diabetic polyneuropathy (BENDIP): results of a randomised, double blind, placebo-controlled clinical study. Exp Clin Endocrinol Diabetes 2008;116(10):600-5. PubMed

See these in context on the Benfotiamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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