Major interaction on record — check this product against your medications before combining. Based on 8 of 11 ingredients. Check your meds →
Dietary supplement

China Tung Hsueh Pills Ingredients & Drug Interactions

by Plum Flower

Tablet Or Pill Category: Botanical
Most serious interaction: Major
The interaction bottom line Most serious interaction: Major

China Tung Hsueh Pills is a dietary supplement by Plum Flower with 11 active ingredients. Its ingredients are commonly taken for menopause symptoms, menstrual cramps and irregular periods, premenstrual syndrome (pms).Based on those ingredients, 1,326 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Corydalis yanhusuo extract, Cinnamomum cassia extract, Rehmannia glutinosa extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of China Tung Hsueh Pills by Plum Flower

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 11 active ingredients.
  • “Proprietary Extract Blend” is a proprietary blend — the label gives one combined amount (1,250 mg) without saying how much of each component you get.

China Tung Hsueh Pills contains 11 ingredients, most of them traditional herbal extracts. The active ingredients include Dong Quai (Angelica sinensis), Frankincense (Boswellia carterii), Myrrh (Commiphora myrrha), Elecampane (Inula helenium), Cassia Cinnamon (Cinnamomum cassia), Rehmannia (Rehmannia glutinosa), Sangre de Grado (Daemonorops draco), and Corydalis yanhusuo.

The product also contains a proprietary extract blend—the exact amounts of each herb aren't listed. Three other ingredients—Salvia miltiorrhiza, Styrax tonkinensis, and Dipsacus asper—round out the formula.

Inactive ingredients include hydrated magnesium silicate, activated carbon, and China wax.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: HIV/AIDS-related diarrhea — rated "Possibly Effective" (Sangre De Grado) (Natural Medicines).
  • On file: Travelers' diarrhea — rated "Possibly Effective" (Sangre De Grado) (Natural Medicines).
  • On file: Genital herpes — rated "Possibly Effective" (Sangre De Grado) (Natural Medicines).
  • On file: Chronic kidney disease (CKD) — rated "Possibly Effective" (Rehmannia) (Natural Medicines).

The evidence base for most of these ingredients is limited. Rehmannia is possibly effective for chronic kidney disease, and Sangre de Grado is possibly effective for HIV/AIDS-related diarrhea and traveler's diarrhea.

For the other conditions the formula may address—anemia, bone health, heart disease, migraines, eczema, acne, back pain, and others—the data we hold shows insufficient reliable evidence to rate whether these ingredients work. That doesn't mean they don't; it means rigorous clinical trials haven't yet established it.

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 8 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 8 of 8.
  • General safety write-ups exist for 8 of 8.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Dong Quai is generally well tolerated but can cause burping and flatulence. Frankincense and Myrrh are generally well tolerated short-term.

Elecampane can trigger allergic skin reactions and stomach upset, especially in people sensitive to ragweed or related plants. Cassia Cinnamon is safe in food amounts but at supplement doses may stress the liver over time due to its coumarin content; rare cases of rash and allergy have been reported.

Corydalis yanhusuo has limited human safety data. Pregnancy and breastfeeding are concerns with several ingredients.

Dong Quai and Myrrh are possibly unsafe or likely unsafe in pregnancy; both may stimulate the uterus. Frankincense, Elecampane, Corydalis yanhusuo, Rehmannia, and Sangre de Grado lack enough safety information—avoid them in pregnancy and while breastfeeding unless your doctor advises otherwise.

Cassia Cinnamon is likely safe in food amounts but avoid medicinal doses in pregnancy. We hold no pregnancy or lactation data for Salvia miltiorrhiza, Styrax tonkinensis, or Dipsacus asper.

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 6 of the 8 matched ingredients can interact with medications — Elecampane, Corydalis Yanhusuo, Myrrh, Dong Quai, Cassia Cinnamon, among others.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 1,327 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your pharmacist if you take blood thinners or antiplatelet drugs (including warfarin and aspirin)—Dong Quai and Corydalis yanhusuo raise bleeding risk. Also watch for blood sugar medications, blood pressure medications, CNS depressants (sleep aids and sedatives), estrogen-based birth control or hormone therapy, or any drug your liver metabolizes.

Myrrh may make warfarin less effective, and Cassia Cinnamon at high doses may stress the liver alongside other liver-stressing drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Major medication interactions have been identified, and safety information is well characterized.

This is a traditional herbal formula with limited clinical evidence for most of its uses. It's not suitable during pregnancy or breastfeeding.

If you take blood thinners, blood pressure or blood sugar medications, sedatives, or any drug metabolized by the liver, you need to check your medications against the tool on this page before starting. Talk to your pharmacist about whether this product fits your health picture.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 8 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 27, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about China Tung Hsueh Pills, straight from the product label.

Brand Plum Flower
Barcode (UPC) 739934860120
Net contents 100 Pill(s); 0.88 Ounce(s); 25 Gram(s)
Market status On market
Date entered into DSLD Jul 27, 2021
DSLD ID 251967
Product type Botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for China Tung Hsueh Pills by Plum Flower, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 Pill(s)
Maximum serving Sizes:
5 Pill(s)
Servings per container
20
UPC/BARCODE
739934860120
IngredientAmount% DV
Proprietary Extract Blend1250 mg--
Salvia miltiorrhiza extract0 NP--
Angelica sinensis extract0 NP--
Styrax tonkinensis0 NP--
Boswellia carterii extract0 NP--
Commiphora myrrha extract0 NP--
Inula helenium extract0 NP--
Cinnamomum cassia extract0 NP--
Rehmannia glutinosa extract0 NP--
Dipsacus asper extract0 NP--
Daemonorops draco extract0 NP--
Corydalis yanhusuo extract0 NP--

Other ingredients: hydrated Magnesium Silicate, activated Carbon, China Wax

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

GMP Quality

Made in China Plum Flower quality guaranteed

No pharmaceuticals or dyes Unsulfured, preservative-free herbs when available

Microbial and heavy metal tested Produced at a Good Manufacturing Practices (GMP) certified factory

FDA Statement of Identity

Herbal Supplement

Suggested/Recommended/Usage/Directions

Take 5 pills 3 times daily or as directed by your health care practitioner.

Precautions

Not for use during pregnancy.

Keep out of reach of children.

General Statements

US owned and operated since 1969.

Formula

Scientifically authenticated herbs

See for yourself

China Tung Hsueh Pills by Plum Flower label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in China Tung Hsueh Pills by Plum Flower

These are the 11 active ingredients this product is made of. Select any to open its full monograph.

Serving size5 Pill(s) Dosage formTablet Or Pill Servings per container20 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Extract Blend

1250 mg per serving

Other (inactive) ingredients: Hydrated Magnesium Silicate, Activated Carbon, China Wax. These complete the product’s ingredient list but are not active constituents.

Interaction report

China Tung Hsueh Pills by Plum Flower Drug Interactions

Want to check YOUR meds against China Tung Hsueh Pills?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1,326Drugs
2 Major 1,324 Moderate

Each ingredient & the kinds of drugs it affects

For each ingredient in China Tung Hsueh Pills with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Corydalis yanhusuo extract14 drug types · 1,160 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, Corydalis yanhusuo might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Corydalis yanhusuo contains berberine. In vitro and in vivo research suggest that berberine can inhibit platelet aggregation. Theoretically, Corydalis yanhusuo might also inhibit platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, Corydalis yanhusuo may increase the risk of hypoglycemia when taken with antidiabetes drugs.
Corydalis yanhusuo contains berberine. Clinical research shows that berberine may lower blood glucose levels. Theoretically, Corydalis yanhusuo might also lower blood glucose levels.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, Corydalis yanhusuo might have additive effects with antihypertensive drugs.
Corydalis yanhusuo contains berberine. Animal research suggests that berberine can have hypotensive effects. Also, a clinical study suggests that taking berberine in combination with amlodipine can lower systolic and diastolic blood pressure when compared with amlodipine alone. Theoretically, Corydalis yanhusuo might also reduce blood pressure.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, Corydalis yanhusuo might increase the sedative effects of CNS depressants.
Corydalis yanhusuo contains berberine. Animal research suggests that berberine may have sedative effects. Theoretically, Corydalis yanhusuo might also have CNS depressants effects.

Likelihood Possible Evidence D
Cyclosporine (Neoral, Sandimmune)

Theoretically, Corydalis yanhusuo might increase blood levels of cyclosporine.
Corydalis yanhusuo contains berberine. Preliminary clinical research shows that berberine can reduce metabolism of cyclosporine and increase serum levels, likely through inhibition of cytochrome P450 3A4 (CYP3A4), which metabolizes cyclosporine. Theoretically, Corydalis yanhusuo might also reduce the metabolism of cyclosporine.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, Corydalis yanhusuo might increase serum levels of drugs metabolized by CYP2C9.
Corydalis yanhusuo contains berberine. Preliminary clinical research shows that berberine can inhibit CYP2C9. Theoretically, Corydalis yanhusuo might also inhibit CYP2C9.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, Corydalis yanhusuo might increase serum levels of drugs metabolized by CYP2D6.
Corydalis yanhusuo contains berberine. In vitro research and preliminary clinical evidence show that berberine can inhibit CYP2D6. Theoretically, Corydalis yanhusuo might also inhibit CYP2D6.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, Corydalis yanhusuo might increase serum levels of drugs metabolized by CYP3A4.
Corydalis yanhusuo contains berberine. In vitro research and preliminary clinical research show that berberine moderately inhibits CYP3A4. Theoretically, Corydalis yanhusuo might also inhibit CYP3A4.

Likelihood Possible Evidence D
Dextromethorphan (Robitussin Dm, Others)

Theoretically, Corydalis yanhusuo may increase serum levels of dextromethorphan.
Corydalis yanhusuo contains berberine. Preliminary clinical research shows that berberine can inhibit cytochrome P450 2D6 (CYP2D6) activity and reduce the metabolism of dextromethorphan. Theoretically, Corydalis yanhusuo may also inhibit the metabolism of dextromethorphan.

Likelihood Possible Evidence D
Losartan (Cozaar)

Theoretically, Corydalis yanhusuo might reduce the therapeutic effects of losartan by decreasing its conversion to its active form.
Corydalis yanhusuo contains berberine. Preliminary clinical research suggests that berberine can inhibit cytochrome P450 2C9 (CYP2C9) activity and reduce metabolism of losartan. Theoretically, Corydalis yanhusuo might also inhibit the metabolism of losartan.

Likelihood Possible Evidence D
Metformin (Glucophage)

Theoretically, Corydalis yanhusuo might increase the therapeutic and adverse effects of metformin.
Corydalis yanhusuo contains berberine. In vitro and animal studies show that berberine can increase the systemic exposure and half-life of metformin, potentially increasing metformin's effects and side effects. This interaction seems to be most apparent when berberine is administered 2 hours prior to metformin. Taking berberine and metformin at the same time does not appear to increase systemic exposure to metformin. It is unclear if Corydalis yanhusuo might have this same effect.

Likelihood Possible Evidence D
Midazolam (Versed)

Theoretically, Corydalis yanhusuo might reduce metabolism of midazolam, which might increase the risk of severe adverse effects.
Corydalis yanhusuo contains berberine. Preliminary clinical research shows that berberine can inhibit cytochrome P450 3A4 (CYP3A4) activity and reduce metabolism of midazolam. Theoretically, Corydalis yanhusuo might also inhibit the metabolism of midazolam.

Likelihood Possible Evidence D
Pentobarbital (Nembutal)

Theoretically, Corydalis yanhusuo might increase the sedative effect of pentobarbital.
Corydalis yanhusuo contains berberine. Animal research shows that berberine can prolong pentobarbital-induced sleeping time. Theoretically, Corydalis yanhusuo might increase the sedative effects of pentobarbital.

Likelihood Possible Evidence D
Tacrolimus (Prograf)

Theoretically, Corydalis yanhusuo might increase blood levels of tacrolimus.
Corydalis yanhusuo contains berberine. In a 16-year-old patient with idiopathic nephrotic syndrome who was being treated with tacrolimus 6.5 mg twice daily, intake of berberine 200 mg three times daily increased the blood concentration of tacrolimus from 8 to 22 ng/mL. Following a reduction of the tacrolimus dose to 3 mg daily, blood levels of tacrolimus decreased to 12 ng/mL. It is unclear if Corydalis yanhusuo might have this same effect.

Likelihood Possible Evidence D

Cinnamomum cassia extract2 drug types · 442 drugs

Antidiabetes Drugs

Theoretically, cassia cinnamon may have additive effects with antidiabetes drugs.
Cassia cinnamon may lower blood glucose levels, and have additive effects in patients treated with antidiabetic agents. Dose adjustments to diabetes medications might be necessary.

Likelihood Possible Evidence B
Hepatotoxic Drugs

Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
There is some concern that ingesting large amounts of cassia cinnamon for an extended duration might cause hepatotoxicity in some people. Cassia cinnamon contains coumarin, which can cause hepatotoxicity in animal models. In humans, very high doses of coumarin from 50-7000 mg/day can result in hepatotoxicity that resolves when coumarin use is discontinued. Lower amounts might also cause liver problems in sensitive people, such as those with liver disease or those taking potentially hepatotoxic agents.

Likelihood Possible Evidence D

Rehmannia glutinosa extract2 drug types · 258 drugs

Antidiabetes Drugs

Theoretically, rehmannia might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research shows that rehmannia may have hypoglycemic effects.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, rehmannia might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research shows that rehmannia may have hypotensive effects. Laboratory research shows that formulations of dried and processed rehmannia root inhibit angiotensin-converting enzyme (ACE).

Likelihood Possible Evidence D

Inula helenium extract1 drug type · 248 drugs

Cns Depressants

Theoretically, elecampane may cause additive sedative effects when taken with CNS depressants.
Elecampane might have sedative effects.

Likelihood Possible Evidence D

Angelica sinensis extract3 drug types · 163 drugs

Warfarin (Coumadin)

Dong quai may increase the risk of bleeding when used with warfarin.
Case reports suggest that concomitant use of dong quai with warfarin can increase the anticoagulant effects of warfarin and increase the risk of bleeding. In one case, after 4 weeks of taking dong quai 565 mg once or twice daily, the international normalized ratio (INR) increased to 4.9. The INR normalized 4 weeks after discontinuation of dong quai.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, dong quai may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Animal studies suggest that dong quai has antithrombin activity and inhibits platelet aggregation due to its coumarin components. Additionally, some case reports in humans suggest that dong quai can increase the anticoagulant effects of warfarin. However, clinical research in healthy adults shows that taking 1 gram of dong quai root daily for 3 weeks does not significantly inhibit platelet aggregation or cause bleeding. Until more is known, use dong quai with caution in patients taking antiplatelet/anticoagulant drugs.

Likelihood Possible Evidence D
Estrogens

Theoretically, dong quai may reduce the effects of estrogens.
Dong quai has estrogenic effects. Theoretically, concomitant use of large amounts of dong quai might interfere with hormone replacement therapy due to competition for estrogen receptors.

Likelihood Possible Evidence D

Commiphora myrrha extract2 drug types · 88 drugs

Antidiabetes Drugs

Theoretically, myrrh might increase the risk of hypoglycemia when taken with antidiabetes drugs.
In vitro and animal research suggests that myrrh has hypoglycemic effects.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, myrrh might decrease the effectiveness of warfarin.
In one case, a patient who was previously stable on warfarin had a significant decline in international normalized ratio (INR) following consumption of an aqueous extract of myrrh.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for China Tung Hsueh Pills, from the product label.

Plum Flower

Name
Mayway Herbs
City
Oakland
State
CA
Web Address
www.plumflowerherbs.com
Pharmacist Counseling Corner

China Tung Hsueh Pills by Plum Flower: Common Questions

Does China Tung Hsueh Pills by Plum Flower interact with any medications?
Yes. Based on its ingredients, China Tung Hsueh Pills has a known interaction with 1,326 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
China Tung Hsueh Pills contains 11 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No. Dong Quai and Myrrh are possibly or likely unsafe in pregnancy and may stimulate the uterus. Frankincense, Elecampane, Corydalis yanhusuo, Rehmannia, and Sangre de Grado don't have enough safety data—you shouldn't use them while pregnant or nursing. Talk to your doctor or pharmacist before taking any supplement if you're pregnant, planning pregnancy, or breastfeeding.
What's Dong Quai, and why is it in this formula?
Dong Quai is the root of Angelica sinensis, a traditional Chinese herb. It's used in formulas like this one for blood circulation and women's health. In this product it's paired with other herbs, though the exact amounts aren't labeled.
Does this actually work for what it claims?
The evidence is mixed. Rehmannia is possibly effective for chronic kidney disease, and Sangre de Grado is possibly effective for certain types of diarrhea. For most other uses—anemia, bone health, migraines—the data we hold just isn't strong enough to say either way yet.
What side effects should I watch for?
Most users tolerate it fine. Dong Quai may cause burping and gas. Elecampane can trigger allergic skin reactions or stomach upset, especially if you're sensitive to ragweed or related plants. At high doses, Cassia Cinnamon may stress your liver. If you notice a rash, trouble breathing, or unusual pain, stop and call your pharmacist.
Can I take this with my birth control pills?
Dong Quai has estrogenic effects and theoretically may interfere with estrogen-based contraceptives. Check the checker tool with your specific pill, and ask your pharmacist or doctor to be sure.
Is this safe long-term?
Most of these herbs have limited long-term human safety data. Cassia Cinnamon, if taken at high doses for months, raises concern about liver stress over time. Frankincense and most others are generally used short-term in traditional practice. Talk to your pharmacist about your timeline and health before committing to long-term use.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

China Tung Hsueh Pills label
Go deeper

The Full Monographs Behind China Tung Hsueh Pills’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Dong Quai

Interacts with 163 drugs

Dong Quai is a traditional Chinese herb often called "female ginseng" and is mostly used for menstrual and menopausal complaints. High-quality scientific evidence that it works for these use...

Read the full Dong Quai monograph →
Herb & supplement monograph

Frankincense

Frankincense is the aromatic resin of the Boswellia tree and is best known for its boswellic acids, which may help with inflammation and joint pain. Early research is promising for condition...

Read the full Frankincense monograph →
Herb & supplement monograph

Myrrh

Interacts with 88 drugs

Myrrh is a fragrant gum resin from Commiphora trees that has long been used in mouthwashes, throat remedies, and skin care. Modern evidence for most of its uses is limited and comes mostly f...

Read the full Myrrh monograph →
Herb & supplement monograph

Elecampane

Interacts with 248 drugs

Elecampane is a traditional herb used mainly for coughs and other respiratory complaints, and as a bitter for digestion. Modern human evidence is very limited, so it should be seen as a folk...

Read the full Elecampane monograph →
Herb & supplement monograph

Cassia Cinnamon

Interacts with 442 drugs

Cassia cinnamon is the common, inexpensive cinnamon used in cooking, and it is also taken as a supplement, most often for blood sugar support. The evidence for its health benefits is mixed a...

Read the full Cassia Cinnamon monograph →
Herb & supplement monograph

Rehmannia

Interacts with 258 drugs

Rehmannia is a root used for centuries in Traditional Chinese Medicine, often to 'tonify' the kidneys and support energy or blood health. Human evidence for most modern uses is limited, so i...

Read the full Rehmannia monograph →
Herb & supplement monograph

Sangre De Grado

Sangre de Grado is a red tree sap from the Amazon rainforest used traditionally for diarrhea, wounds, and skin problems. Some of its compounds have been studied scientifically, and one purif...

Read the full Sangre De Grado monograph →
Herb & supplement monograph

Corydalis Yanhusuo

Interacts with 1,160 drugs

Corydalis yanhusuo is a traditional Chinese herb used mainly for pain. Some early laboratory and animal research suggests its compounds may affect pain and the nervous system, but high-quali...

Read the full Corydalis Yanhusuo monograph →
Sources

Sources & How We Checked

China Tung Hsueh Pills's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 87 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Dong Quai 19 references
  1. Hirata JD, Swiersz LM, Zell B, et al. Does dong quai have estrogenic effects in postmenopausal women? A double-blind, placebo-controlled trial. Fertil Steril 1997;68:981-6. PubMed
  2. Page RL II, Lawrence JD. Potentiation of warfarin by dong quai. Pharmacotherapy 1999;19:870-6. PubMed
  3. Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
  4. Eagon PK, Elm MS, Hunter DS, et al. Medicinal herbs: modulation of estrogen action. Era of Hope Mtg, Dept Defense; Breast Cancer Res Prog, Atlanta, GA 2000;Jun 8-11.
  5. Dr. Duke's Phytochemical and Ethnobotanical Databases. Available at: http://www.ars-grin.gov/duke/.
  6. Amato P, Christophe S, Mellon PL. Estrogenic activity of herbs commonly used as remedies for menopausal symptoms. Menopause 2002;9:145-50. PubMed
  7. Shi M, Chang L, He G. [Stimulating action of Carthamus tinctorius L., Angelica sinensis (Oliv.) Diels and Leonurus sibiricus L. on the uterus]. Zhongguo Zhong Yao Za Zhi 1995;20:173-5, 192.
  8. Hoult JR, Paya M. Pharmacological and biochemical actions of simple coumarins: natural products with therapeutic potential. Gen Pharmacol 1996;27:713-22.. PubMed
  9. Cheong JL, Bucknall R. Retinal vein thrombosis associated with a herbal phytoestrogen preparation in a susceptible patient. Postgrad Med J 2005;81:266-7.. PubMed
  10. Chang CJ, Chiu JH, Tseng LM, et al. Modulation of HER2 expression by ferulic acid on human breast cancer MCF7 cells. Eur J Clin Invest 2006;36:588-96. PubMed
  11. Chuang CH, Doyle P, Wang JD, et al. Herbal medicines used during the first trimester and major congenital malformations: an analysis of data from a pregnancy cohort study. Drug Saf 2006;29:537-48. PubMed
  12. Lau CBS, Ho TCY, Chan TWL, Kim SCF. Use of dong quai (Angelica sinensis) to treat peri- and postmenopausal symptoms in women with breast cancer: is it appropriate? Menopause 2005;12:734-40.
  13. Ellis GR, Stephens MR. Untitled (photograph and a brief case report). BMJ 1999;319:650.
  14. Nambiar, S., Schwartz, R. H., and Constantino, A. Hypertension in mother and baby linked to ingestion of Chinese herbal medicine. West J Med 1999;171(3):152.
  15. Lee, S. K., Cho, H. K., Cho, S. H., Kim, S. S., Nahm, D. H., and Park, H. S. Occupational asthma and rhinitis caused by multiple herbal agents in a pharmacist. Ann.Allergy Asthma Immunol. 2001;86(4):469-474. PubMed
  16. Xu, J. and Li, G. [Observation on short-term effects of Angelica injection on chronic obstructive pulmonary disease patients with pulmonary hypertension]. Zhongguo Zhong Xi Yi Jie He Za Zhi 2000;20(3):187-189.
  17. Scott, G. N. and Elmer, G. W. Update on natural product--drug interactions. Am J Health Syst.Pharm 2-15-2002;59(4):339-347. PubMed
  18. Circosta, C., Pasquale, R. D., Palumbo, D. R., Samperi, S., and Occhiuto, F. Estrogenic activity of standardized extract of Angelica sinensis. Phytother.Res. 2006;20(8):665-669.
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Frankincense 2 references
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Myrrh 8 references
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Elecampane 5 references
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Cassia Cinnamon 20 references
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Rehmannia 3 references
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Sangre De Grado 9 references
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Corydalis Yanhusuo 21 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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