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Dietary supplement

David Winston's Women's Transition Compound Ingredients & Drug Interactions

by Herbalist & Alchemist

David Winston's Women's Transition Compound label
See full label image
Liquid Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking David Winston's Women's Transition Compound against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

David Winston's Women's Transition Compound is a dietary supplement by Herbalist & Alchemist with 7 active ingredients. Its ingredients are commonly taken for menopause symptoms, menstrual cramps and irregular periods, premenstrual syndrome (pms).Based on those ingredients, 1,545 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Sage herb extract, Black Cohosh Root Extract, Dong Quai root extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against David Winston's Women's Transition Compound by Herbalist & Alchemist

Ask about any prescription or over-the-counter medication and we check it for interactions with David Winston's Women's Transition Compound by Herbalist & Alchemist — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of David Winston's Women's Transition Compound by Herbalist & Alchemist

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 7 active ingredients.
  • “Proprietary Blend Extract” is a proprietary blend — the label gives one combined amount (3 mL) without saying how much of each component you get.

This liquid formula contains 7 active ingredients. The core extract is Dong Quai root, which has been used traditionally in Chinese herbalism.

The blend also includes Shatavari root extract (also called asparagus racemosus), Black Cohosh root extract, Sage herb extract, Night Blooming Cereus stem extract, Oat Milky Seed extract, and Chaste Tree Berry extract (vitex agnus-castus). The product is suspended in ethyl alcohol and distilled water as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: balancing for perimenopause.
  • We looked for evidence on: Menopausal symptoms, Dysmenorrhea, Amenorrhea, Mastalgia, Anxiety, Insomnia — and 4 related terms.
  • The strongest evidence on file: Sage is rated "Possibly Effective" for Menopausal symptoms (Natural Medicines).
  • Also on file: Black Cohosh is rated "Possibly Effective" for Menopausal symptoms.
  • Also on file: Vitex Agnus-castus is rated "Possibly Effective" for Mastalgia, Premenstrual syndrome (PMS).

Evidence for most ingredients in this blend remains limited. Black Cohosh has Possibly Effective evidence for menopausal symptoms.

Sage herb extract is rated Possibly Effective for menopausal symptoms, cognitive function, and high cholesterol (hyperlipidemia). Chaste Tree Berry is Possibly Effective for premenstrual syndrome (PMS) and breast pain (mastalgia).

Oat Milky Seed extract is rated Likely Effective for high cholesterol and heart disease. For the other ingredients—Dong Quai, Shatavari, and Night Blooming Cereus—the evidence we hold shows Insufficient Reliable Evidence To Rate them for their traditional uses, or no effectiveness ratings are on file.

The evidence, ingredient by ingredient Dong Quai Asparagus Racemosus Black Cohosh Sage Cereus Oats Vitex Agnus-castus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 7 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 7 of 7.
  • General safety write-ups exist for 7 of 7.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most ingredients are generally well tolerated in typical doses. Dong Quai may increase bleeding risk and cause skin sensitivity to sunlight; it should be avoided in pregnancy and during breastfeeding due to insufficient safety data and possible effects on the uterus.

Black Cohosh is generally well tolerated short-term but carries a rare risk of liver problems, so medical guidance is wise; avoid in pregnancy and while breastfeeding. Sage is considered safe as a food and short-term tea but should be used cautiously in concentrated extract form; avoid medicinal amounts in pregnancy due to thujone content, and avoid during breastfeeding because sage traditionally reduces milk supply.

Night Blooming Cereus has limited safety data and possible heart effects—professional guidance is important; avoid in pregnancy and while breastfeeding. Shatavari is traditionally well tolerated but high-quality safety data are limited; safety in pregnancy is not well established, and reliable breastfeeding data are lacking.

Chaste Tree Berry is often well tolerated short-term but may affect hormones; it is not recommended in pregnancy or while breastfeeding. Oat Milky Seed extract is safe when eaten as food in pregnancy and while breastfeeding; concentrated supplement forms are less studied.

Common side effects across the blend may include nausea, diarrhea, headache, dizziness, and digestive upset.

Side effects, ingredient by ingredient Dong Quai Asparagus Racemosus Black Cohosh Sage Cereus Oats Vitex Agnus-castus

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 7 of the 7 matched ingredients can interact with medications — Sage, Cereus, Oats, Black Cohosh, Dong Quai, among others.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; seizure medications; diabetes medications; heart-rhythm medications; lithium.
  • For scale: 1,546 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, have your pharmacist check: blood thinners and antiplatelet drugs (Major risk with Dong Quai and warfarin specifically), hormone replacement therapy and oral contraceptives, insulin and diabetes medications, antidepressants (especially SSRIs and SNRIs), blood pressure medications, liver-metabolized drugs (the product inhibits multiple liver enzymes), cardiac medications including digoxin, antipsychotics, and dopamine agonists.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This product is formulated for women's transition years, but its ingredients interact with several important medication classes. If you take a blood thinner, hormone therapy, diabetes medication, antidepressant, heart medication, blood pressure drug, or antipsychotic, check your specific medications with the tool on this page before starting.

Talk with your pharmacist or doctor—especially if you're pregnant, breastfeeding, or have liver concerns.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 7 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about David Winston's Women's Transition Compound, straight from the product label.

Brand Herbalist & Alchemist
Barcode (UPC) 667056130398
Net contents 2 Fluid Ounce(s); 60 mL
Market status On market
Date entered into DSLD Sep 25, 2025
DSLD ID 340217
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Kosher, Women (not pregnant or lactating), Adult Female (18 - 50 Years), Menopause, Seniors/Mature (>50 Years) - Women ONLY
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for David Winston's Women's Transition Compound by Herbalist & Alchemist, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 mL
Maximum serving Sizes:
3 mL
Servings per container
20
UPC/BARCODE
667056130398
IngredientAmount% DV
Proprietary Blend Extract3 mL--
Dong Quai root extract0 NP--
Shatavari root extract0 NP--
Black Cohosh Root Extract0 NP--
Sage herb extract0 NP--
Night Blooming Cereus stem extract0 NP--
Oat Milky Seed Extract0 NP--
Chaste Tree Berry Extract0 NP--

Other ingredients: Ethyl Alcohol, Water, Distilled

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Balancing for perimenopause

OK (Kosher)

FDA Statement of Identity

Herbal Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: 40-60 drops (2-3 mL) in juice or water. Take 3-4 times per day. Shake well before using.

Precautions

Contraindications: Do not use during pregnancy.

Keep out of children's reach

FDA Disclaimer Statement

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Certified B Corporation OK (Kosher)

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

David Winston's Women's Transition Compound by Herbalist & Alchemist label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

David Winston's Women's Transition Compound label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in David Winston's Women's Transition Compound by Herbalist & Alchemist

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 mL Dosage formLiquid Servings per container20 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Other (inactive) ingredients: Ethyl Alcohol, Water, Distilled. These complete the product’s ingredient list but are not active constituents.

Interaction report

David Winston's Women's Transition Compound by Herbalist & Alchemist Drug Interactions

Want to check YOUR meds against David Winston's Women's Transition Compound?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,545Drugs
2 Major 1,536 Moderate 7 Minor

Ingredients driving the most interactions

Sage herb extract 1,296
Black Cohosh Root Extract 652
Dong Quai root extract 163
Chaste Tree Berry Extract 121
Oat Milky Seed Extract 86

Individual Drug Interactions

The ingredients in David Winston's Women's Transition Compound interact with 1,545 drugs. Click any drug to see the details.

7 of the 7 ingredients in David Winston's Women's Transition Compound interact with drugs. Each result below shows which ingredient is responsible. Sage herb extract Black Cohosh Root Extract Dong Quai root extract Chaste Tree Berry Extract Oat Milky Seed Extract Shatavari root extract Night Blooming Cereus stem extract

Each ingredient & the kinds of drugs it affects

For each ingredient in David Winston's Women's Transition Compound with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Sage herb extract14 drug types · 1,296 drugs

Anticholinergic Drugs

Theoretically, sage might decrease the clinical effects of anticholinergic drugs.
In vitro evidence suggests that common sage (Salvia officinalis) and Spanish sage (Salvia lavandulaefolia) can inhibit acetylcholinesterase and might increase acetylcholine levels.

Likelihood Possible Evidence D
Anticonvulsants

Theoretically, sage might interfere with the clinical effects of anticonvulsant drugs.
Some species of sage can cause convulsions when consumed in large quantities.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking sage with antidiabetes drugs might increase the risk of hypoglycemia.
In patients with polycystic ovary syndrome (PCOS) or inadequately controlled type 2 diabetes, common sage (Salvia officinalis) has demonstrated hypoglycemic activity. However, other clinical research in patients with inadequately controlled type 2 diabetes shows that common sage extract does not lower fasting blood glucose levels.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, sage might increase or decrease the effects of antihypertensive drugs.
Animal research suggests that common sage (Salvia officinalis) can cause prolonged blood pressure reduction. However, clinical research suggests that Spanish sage (Salvia lavandulaefolia) can increase blood pressure in some people with hypertension. Until more is known, use with caution.

Likelihood Possible Evidence D
Benzodiazepines

Theoretically, taking sage might increase the sedative and adverse effects of benzodiazepines.
In vitro evidence suggests that certain components of common sage (Salvia officinalis) can bind to benzodiazepine receptors. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cholinergic Drugs

Theoretically, sage might have additive effects when used with cholinergic drugs.
In vitro evidence suggests that common sage (Salvia officinalis) and Spanish sage (Salvia lavandulaefolia) can inhibit acetylcholinesterase and might increase acetylcholine levels.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, taking sage might increase the sedative and adverse effects of CNS depressants.
Some constituents of sage have CNS depressant activity.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP2C19.
In vitro evidence suggests that aqueous extracts of sage can inhibit CYP2C19. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP2C9.
In vitro evidence suggests that aqueous extracts of sage can inhibit CYP2C9. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP2D6.
In vitro evidence suggests that aqueous extracts of sage can inhibit CYP2D6. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Theoretically, sage might decrease the levels and clinical effects of drugs metabolized by CYP2E1.
Animal research suggests that drinking common sage (Salvia officinalis) tea increases the expression of CYP2E1. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP3A4.
In vitro evidence suggests that aqueous extracts of sage can inhibit CYP3A4. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Estrogens

Theoretically, sage might interfere with hormone therapy.
In vitro evidence suggests that geraniol, a constituent of Spanish sage (Salvia lavandulaefolia), exerts estrogenic activity. The clinical significance of this effect is unclear.

Likelihood Possible Evidence D
P-Glycoprotein Substrates

Theoretically, sage might increase levels of drugs transported by P-glycoprotein.
In vitro research suggests that common sage (Salvia officinalis) can inhibit the multi-drug transporter protein, P-glycoprotein. This effect has not been reported in humans.

Likelihood Possible Evidence D
Sage herb extract full monograph & interactions

Black Cohosh Root Extract7 drug types · 652 drugs

Atorvastatin (Lipitor)

Taking black cohosh with atorvastatin might increase the risk for elevated liver function tests.
In one case report, a patient taking atorvastatin (Lipitor) developed significantly elevated liver function enzymes after starting black cohosh 100 mg four times daily. Liver enzymes returned to normal when black cohosh was discontinued. It is unclear whether the elevated liver enzymes were due to black cohosh itself or an interaction between atorvastatin and black cohosh.

Likelihood Possible Evidence D
Cisplatin (Platinol-Aq)

Theoretically, black cohosh may reduce the clinical effects of cisplatin.
Animal research suggests that black cohosh might decrease the cytotoxic effect of cisplatin on breast cancer cells.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Some research suggests that black cohosh might inhibit CYP2D6, but there is conflicting evidence.
Some clinical research suggests that black cohosh might modestly inhibit CYP2D6 and increase levels of drugs metabolized by this enzyme. However, contradictory clinical research shows a specific black cohosh product (Remifemin, Enzymatic Therapy) 40 mg twice daily does not significantly inhibit metabolism of a CYP2D6 substrate in healthy study volunteers. Until more is known, use black cohosh cautiously in patients taking drugs metabolized by CYP2D6.

Likelihood Possible Evidence B
Estrogens

Theoretically, black cohosh may alter the effects of estrogen therapy.
Some research suggests that black cohosh has estrogenic effects. This may enhance or inhibit the effects of estrogen therapy.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, taking black cohosh with hepatotoxic drugs may increase the risk of liver damage.
There is concern that black cohosh might be linked to cases of liver failure and autoimmune hepatitis.

Likelihood Possible Evidence D
Serotonergic Drugs

Combining serotonergic drugs with black cohosh might cause additive serotonergic effects.
Black cohosh might increase the risk of serotonin syndrome when combined with other serotonergic drugs. Black cohosh acts as an agonist at several serotonin receptor subtypes and might interact with other serotonergic medications. In one case, a 55-year-old female who had been on stable treatment with sertraline 50 mg and duloxetine 60 mg daily developed serotonin syndrome after taking black cohosh extract 40 mg daily for 3 days.

Likelihood Possible Evidence D
Organic Anion-Transporting Polypeptide Substrates (Oatp)

Black cohosh may inhibit one form of OATP, OATP2B1, which could reduce the bioavailability and clinical effects of OATP2B1 substrates.
In vitro research shows that black cohosh modestly inhibits OATP2B1. OATPs are expressed in the small intestine and liver and are responsible for the uptake of drugs and other compounds into the body. Inhibition of OATP may reduce the bioavailability of oral drugs that are substrates of OATP.

Likelihood Possible Evidence D
Black Cohosh Root Extract full monograph & interactions

Dong Quai root extract3 drug types · 163 drugs

Warfarin (Coumadin)

Dong quai may increase the risk of bleeding when used with warfarin.
Case reports suggest that concomitant use of dong quai with warfarin can increase the anticoagulant effects of warfarin and increase the risk of bleeding. In one case, after 4 weeks of taking dong quai 565 mg once or twice daily, the international normalized ratio (INR) increased to 4.9. The INR normalized 4 weeks after discontinuation of dong quai.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, dong quai may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Animal studies suggest that dong quai has antithrombin activity and inhibits platelet aggregation due to its coumarin components. Additionally, some case reports in humans suggest that dong quai can increase the anticoagulant effects of warfarin. However, clinical research in healthy adults shows that taking 1 gram of dong quai root daily for 3 weeks does not significantly inhibit platelet aggregation or cause bleeding. Until more is known, use dong quai with caution in patients taking antiplatelet/anticoagulant drugs.

Likelihood Possible Evidence D
Estrogens

Theoretically, dong quai may reduce the effects of estrogens.
Dong quai has estrogenic effects. Theoretically, concomitant use of large amounts of dong quai might interfere with hormone replacement therapy due to competition for estrogen receptors.

Likelihood Possible Evidence D
Dong Quai root extract full monograph & interactions

Chaste Tree Berry Extract5 drug types · 121 drugs

Antipsychotic Drugs

Theoretically, vitex agnus-castus could interfere with the activity of antipsychotic drugs.
Vitex agnus-castus might interfere with the action of dopamine antagonists such as antipsychotic drugs due to its dopamine agonist effects.

Likelihood Possible Evidence D
Contraceptive Drugs

Theoretically, vitex agnus-castus could interfere with oral contraceptives.
Vitex agnus-castus might interfere with the efficacy of oral contraceptives due to possible hormone modulating activity.

Likelihood Possible Evidence B
Dopamine Agonists

Theoretically, vitex agnus-castus could interfere with dopamine agonists.
Vitex agnus-castus might potentiate the actions of dopaminergic agonists due to possible dopaminergic effects.

Likelihood Possible Evidence D
Estrogens

Theoretically, vitex agnus-castus could interfere with the activity of estrogens.
Vitex agnus-castus has hormone modulating activity that can interfere with the efficacy of hormone replacement therapy.

Likelihood Probable Evidence D
Metoclopramide (Reglan)

Theoretically, dopaminergic effects of vitex agnus-castus could interfere with metoclopramide.
Vitex agnus-castus might interfere with the action of dopamine antagonists such as metoclopramide due to its possible dopaminergic effects.

Likelihood Possible Evidence D
Chaste Tree Berry Extract full monograph & interactions

Oat Milky Seed Extract2 drug types · 86 drugs

Antidiabetes Drugs

Theoretically, oats may have additive effects with antidiabetic agents and might increase the risk of hypoglycemia.
Consuming oats can decrease blood glucose in patients with diabetes. In those who require insulin, taking oats 100 grams daily for 2 days reduces the insulin dose required to achieve metabolic control.

Likelihood Possible Evidence D
Insulin

Concomitant use of oats and insulin might increase the risk of hypoglycemia.
In patients with insulin-dependent type 2 diabetes, taking oats 100 grams daily for 2 days reduces the insulin dose required to achieve metabolic control.

Likelihood Possible Evidence B
Oat Milky Seed Extract full monograph & interactions

Shatavari root extract2 drug types · 76 drugs

Diuretic Drugs

Theoretically, asparagus racemosus root might increase diuresis and electrolyte loss when used with diuretic drugs.
Animal studies show that asparagus racemosus root has diuretic effects when used in high doses. This effect has not been reported in humans.

Likelihood Possible Evidence D
Lithium

Theoretically, Asparagus racemosus root could reduce excretion and increase levels of lithium.
Animal research suggests that Asparagus racemosus root has diuretic properties when used in high doses. Therefore, it might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Shatavari root extract full monograph & interactions

Night Blooming Cereus stem extract2 drug types · 10 drugs

Digoxin (Lanoxin)

Cereus may potentiate the actions of cardiac glycosides and may enhance the effect of other cardiac drugs.

Likelihood Possible Evidence D
Monoamine Oxidase Inhibitors (Maois)

Theoretically, excessive doses of cereus may interact with MAOIs, because of the tyramine content.

Likelihood Possible Evidence D
Night Blooming Cereus stem extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for David Winston's Women's Transition Compound, from the product label.

Herbalist & Alchemist

See all Herbalist & Alchemist products
Name
Herbalist & Alchemist, Inc.
City
Washington
State
NJ
ZipCode
07882
Phone Number
800-611-8235
Web Address
www.herbalist-alchemist.com
Pharmacist Counseling Corner

David Winston's Women's Transition Compound by Herbalist & Alchemist: Common Questions

Does David Winston's Women's Transition Compound by Herbalist & Alchemist interact with any medications?
Yes. Based on its ingredients, David Winston's Women's Transition Compound has a known interaction with 1,545 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
David Winston's Women's Transition Compound contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this product work for hot flashes and night sweats?
Black Cohosh and Sage extract in the blend are both rated Possibly Effective for menopausal symptoms based on our data. The other ingredients don't have established evidence for hot flashes. Individual results vary, so talk with your doctor about whether this blend makes sense for you.
Can I take this while pregnant?
No. Dong Quai should be avoided in pregnancy because it may stimulate the uterus and affect bleeding. Black Cohosh and Chaste Tree Berry are also not recommended due to possible effects on the uterus and limited safety data. Sage should not be taken in medicinal amounts during pregnancy. Talk with your doctor before using any herbal supplement while pregnant.
Can I take this while breastfeeding?
The safety data are not clear for most ingredients in this formula while breastfeeding. Dong Quai is best avoided. Black Cohosh and Night Blooming Cereus should be avoided, and Chaste Tree Berry is not recommended because it may affect milk-related hormones. Sage traditionally reduces milk supply, so medicinal amounts should be avoided. Oat extract is generally safe as food. Talk with your pharmacist or doctor about safety for breastfeeding.
What are the most common side effects?
The blend may cause nausea, diarrhea, headache, dizziness, abdominal pain, or flatulence. Black Cohosh may cause breast tenderness, irritability, or rash. Sage can cause agitation or skin reactions. Chaste Tree Berry may cause irregular menstrual bleeding. These are usually mild and may subside with continued use.
Does this product contain any ingredients I couldn't check for interactions?
No. All active ingredients in this product have interaction monographs we could check. However, we hold no interaction data for one ingredient—the proprietary blend extract container itself (its components are the individual ingredients listed). Always verify your own medications with the tool on this page.
Is this product safe for most people?
The product is generally well tolerated by many people at typical doses, but it contains ingredients with significant interactions and cautions. Because it affects hormones, liver enzymes, bleeding risk, and heart function, it's not appropriate for everyone. Check with your pharmacist about your individual situation before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

David Winston's Women's Transition Compound label
Go deeper

The Full Monographs Behind David Winston's Women's Transition Compound’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Dong Quai

Interacts with 163 drugs

Dong Quai is a traditional Chinese herb often called "female ginseng" and is mostly used for menstrual and menopausal complaints. High-quality scientific evidence that it works for these use...

Read the full Dong Quai monograph → Herb & supplement monograph

Asparagus Racemosus

Interacts with 76 drugs

Asparagus racemosus, often called shatavari, is an Ayurvedic herb traditionally used to support women's health, digestion, and overall vitality. Human evidence for most of these uses is limi...

Read the full Asparagus Racemosus monograph → Herb & supplement monograph

Black Cohosh

Interacts with 652 drugs

Black cohosh is a North American plant most often used to ease menopause symptoms like hot flashes, but the research is mixed and far from settled. It is generally well tolerated for short-t...

Read the full Black Cohosh monograph → Herb & supplement monograph

Sage

Interacts with 1,296 drugs

Sage is a common kitchen herb that is generally safe in food amounts and is traditionally used for sore throats, digestion, sweating, and memory. Some early research is encouraging for sore...

Read the full Sage monograph → Herb & supplement monograph

Cereus

Interacts with 10 drugs

Cereus (often called night-blooming cereus) is a cactus traditionally used in folk and homeopathic medicine for heart-related complaints like palpitations. High-quality human evidence suppor...

Read the full Cereus monograph → Herb & supplement monograph

Oats

Interacts with 86 drugs

Oats are a well-studied whole grain whose soluble fiber (beta-glucan) can help lower cholesterol and support heart health when eaten regularly. As a food, oats are safe for most people, and...

Read the full Oats monograph → Herb & supplement monograph

Vitex Agnus-castus

Interacts with 121 drugs

Vitex (chasteberry) is an herbal remedy most often used for PMS and menstrual cycle problems, and the strongest evidence is for easing some PMS symptoms. It is generally well tolerated by ma...

Read the full Vitex Agnus-castus monograph →
Sources

Sources & How We Checked

David Winston's Women's Transition Compound's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 154 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Dong Quai 19 references
  1. Hirata JD, Swiersz LM, Zell B, et al. Does dong quai have estrogenic effects in postmenopausal women? A double-blind, placebo-controlled trial. Fertil Steril 1997;68:981-6. PubMed
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Asparagus Racemosus 1 reference
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Black Cohosh 68 references
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Sage 27 references
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Cereus 3 references
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Oats 13 references
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See these in context on the Vitex Agnus-castus monograph →

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