No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 3 of 8 ingredients. Check your meds →
Dietary supplement

Evozyme Ingredients & Drug Interactions

by Evogen

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Evozyme is a dietary supplement by Evogen with 8 active ingredients. Its ingredients are commonly taken for lactose intolerance, gas and bloating after dairy, diarrhea from dairy foods.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Evozyme by Evogen

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 8 active ingredients.
  • “Evozyme Enzyme Blend” is a proprietary blend — the label gives one combined amount (150 mg) without saying how much of each component you get.
  • “Amylase” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

Evozyme is a capsule containing eight active enzymes. Lactase breaks down lactose (milk sugar), protease breaks down protein, and the others — beta-glucanase, phytase, xylanase, glucoamylase, diastase, and cellulase — work on different carbohydrates and fiber in food.

The capsule itself and maltodextrin are inactive ingredients that help deliver the enzymes.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Digestive enzyme support.
  • We looked for evidence on: Lactose intolerance, Gas and bloating, Diarrhea, Mineral absorption.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).

Lactase is effective for lactose intolerance. For the other seven ingredients — protease, beta-glucanase, phytase, xylanase, glucoamylase, diastase, and cellulase — we hold either no effectiveness data or only ratings of insufficient evidence.

That means we don't have enough solid trial data to say whether they work for any particular condition. If you're considering this product for a specific reason, talk it over with your doctor or pharmacist about what the evidence actually supports.

The evidence, ingredient by ingredient Lactase Proteolytic Enzymes (proteases) Phytase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactase is generally well tolerated and rated likely safe in pregnancy and lactation, though you should still check with your doctor before regular use during pregnancy. Protease is generally well tolerated for most adults but may cause digestive upset or allergic reactions; safety has not been established in pregnancy, so it should be avoided unless your doctor prescribes it, and there is little data during breastfeeding so medical advice is needed first.

Phytase is considered low-risk in foods but has limited human supplement data; there is not enough reliable safety information in pregnancy (avoid unless your doctor advises otherwise), and safety while breastfeeding has not been well studied. Rare allergic reactions to airborne enzyme exposure have been reported in occupational settings, including contact dermatitis, allergic rhinitis, and in some cases occupational asthma or hypersensitivity pneumonitis (a lung inflammation from repeated exposure).

Side effects, ingredient by ingredient Lactase Proteolytic Enzymes (proteases) Phytase

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 3 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Still, we could not verify five of the eight active ingredients (beta-glucanase, xylanase, glucoamylase, diastase, and cellulase), so confirm your exact medications with your doctor or pharmacist before you start.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This product may help if you have lactose intolerance, but the evidence for the other enzymes isn't clear. If you're pregnant, breastfeeding, or taking any medications, talk with your own doctor or pharmacist first — especially about protease and phytase, where pregnancy and breastfeeding safety data are limited or not established.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 21, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Evozyme, straight from the product label.

Brand Evogen
Barcode (UPC) 817189027496
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Jul 21, 2022
DSLD ID 264877
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Evozyme by Evogen, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
817189027496
IngredientAmount% DV
Lactase0 NP--
Protease0 NP--
Beta-Glucanase0 NP--
Phytase0 NP--
Xylanase0 NP--
Glucoamylase0 NP--
Diastase0 NP--
Evozyme Enzyme Blend150 mg--
Amylase0 NP--
Cellulase0 NP--

Other ingredients: Maltodextrin, Vegetable Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions for use: Take 1 capsule with each meal.

Precautions

Warning: Not for use by individuals under the age of 18. Keep out of reach of children.

Do not use if pregnant, expect to become pregnant, or nursing. Consult with a qualified healthcare professional prior to using this product, especially if you are taking any prescription medications.

Do not take this product if you have any prior medical condition, including diabetes or high blood pressure. Discontinue use two weeks prior to surgery or if upset stomach occurs. Do not use if safety seal is broken or missing. This product may contain ingredients banned by certain organizations. User assumes all risks, liabilities or consequences regarding testing.

Do not use if you are allergic or contraindicated to aspirin.

Allergen warning: Manufactured in a facility that manufactures milk, soy, and wheat ingredients.

Storage

Store at room temperature. Keep bottle tightly closed.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

Copyright 2021 Evogen Inc. All rights reserved. Evozyme is a trademark and Evogen is a registered trademark of Evogen Inc.

Formulation

Made in the USA with domestic & international ingredients Premium digestive enzyme support Maximum digestion Absorption Utilization

FDA Statement of Identity

Dietary Supplement

See for yourself

Evozyme by Evogen label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Evozyme by Evogen

These are the 8 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Evozyme Enzyme Blend

150 mg per serving
  • Lactase
  • Protease
  • › Beta-Glucanase
  • Phytase
  • › Xylanase
  • › Glucoamylase
  • › Amylase
  • › Cellulase

Other (inactive) ingredients: Maltodextrin, Vegetable Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Evozyme by Evogen Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Evozyme. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Evozyme, from the product label.

Evogen

See all Evogen products
Name
Evogen Inc.
Street Address
271 E. Hacienda Ave.
City
Campbell
State
CA
ZipCode
95008
Phone Number
1.408.364.1650
Web Address
EvogenNutrition.com
Pharmacist Counseling Corner

Evozyme by Evogen: Common Questions

Does Evozyme by Evogen interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Evozyme. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Evozyme contains 8 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this help with lactose intolerance?
Yes — lactase, one of the active ingredients, is effective for lactose intolerance. The other enzymes in the blend target different carbohydrates and fiber, but we don't have strong evidence they work for any specific condition.
Can I take this while pregnant?
Lactase is rated likely safe in pregnancy, but protease and phytase lack established safety data — the safety notes advise against protease unless your doctor prescribes it, and to avoid phytase unless your doctor advises otherwise. Talk with your own doctor about what's right for you.
Can I take this while breastfeeding?
Lactase is rated likely safe during breastfeeding. Protease and phytase have very limited breastfeeding data, so medical advice is needed before using them. Check with your doctor or pharmacist first.
What are these enzymes for?
Lactase breaks down milk sugar; protease breaks down protein; the others break down different carbohydrates and fiber. Together they're meant to help digest a range of foods.
Are there any side effects?
Protease may cause digestive upset or allergic reactions in some people. Rare allergic reactions to enzyme exposure have been reported, including contact dermatitis, allergic rhinitis, and in occupational settings, asthma or lung inflammation from repeated airborne exposure. If you notice any unusual symptoms, talk to your pharmacist.
Does this interact with my medications?
No interactions are documented in our data for the ingredients we could check. But we couldn't verify five of the eight enzymes, so run your exact medications through the search tool on this page and confirm with your own doctor or pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Evozyme is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Evozyme label
Sources

Sources & How We Checked

Evozyme's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Phytase 7 references
  1. Lei XG, Weaver JD, Mullaney E, Ullah AH, Azain MJ. Phytase, a new life for an "old" enzyme. Annu Rev Anim Biosci. 2013;1:283-309. PubMed
  2. Smuts CM, Matsungo TM, Malan L, et al. Effect of small-quantity lipid-based nutrient supplements on growth, psychomotor development, iron status, and morbidity among 6- to 12-mo-old infants in South Africa: a randomized controlled trial. Am J Clin Nutr. 2 PubMed
  3. van Heemst RC, Sander I, Rooyackers J, et al. Hypersensitivity pneumonitis caused by occupational exposure to phytase. Eur Respir J. 2009;33(6):1507-9. PubMed
  4. Baur X, Melching-Kollmuss S, Koops F, Strassburger K, Zober A. IgE-mediated allergy to phytase -- a new animal feed additive. Allergy. 2002;57(10):943-5. PubMed
  5. Doekes G, Kamminga N, Helwegen L, Heederik D. Occupational IgE sensitisation to phytase, a phosphatase derived from Aspergillus niger. Occup Environ Med. 1999;56(7):454-9. PubMed
  6. Brnic M, Hurrell RF, Songré-Ouattara LT, et al. Effect of phytase on zinc absorption from a millet-based porridge fed to young Burkinabe children. Eur J Clin Nutr. 2017;71(1):137-141. PubMed
  7. Koshy JC, Sharabi SE, Feldman EM, Hollier LH Jr, Patrinely JR, Soparkar CN. Effect of dietary zinc and phytase supplementation on botulinum toxin treatments. J Drugs Dermatol. 2012;11(4):507-12.

See these in context on the Phytase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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